Bile duct papillary neoplasm | Gene-Disease Associations & Pathways | GeDiPNet

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Subtype of: Bile duct cancer

Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
bile duct papillary neoplasm	MONDO_0003455	ACVR2A	Unknown	32100878	Open Targets	Cytokine-cytokine receptor interaction TGF-beta signaling pathway Signaling pathways regulating pluripotency of stem cells +3 more
		APC	Unknown	32100878	Open Targets	Wnt signaling pathway Hippo signaling pathway Signaling pathways regulating pluripotency of stem cells +28 more
		ARID1A	Unknown	32100878	Open Targets	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma +2 more
		ARID2	Unknown	32100878	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		BAP1	Unknown	32100878	Open Targets	Polycomb repressive complex UCH proteinases Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks
		BRAF	Unknown	32100878	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +52 more
		CDKN2A	Unknown	32100878	Open Targets	Endocrine resistance Platinum drug resistance Cell cycle +33 more
		CTNNB1	Unknown	32100878	Open Targets	Rap1 signaling pathway Wnt signaling pathway Hippo signaling pathway +51 more
		ELF3	Unknown	32100878	Open Targets	Pre-NOTCH Transcription and Translation
		ERBB2	Unknown	32100878	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance Platinum drug resistance +48 more
		ERBB3	Unknown	32100878	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway ErbB signaling pathway +19 more
		FBXW7	Unknown	32100878	Open Targets	Ubiquitin mediated proteolysis Constitutive Signaling by NOTCH1 PEST Domain Mutants Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling +3 more
		GNAS	Unknown	24312577 24061513 32100878 26506885 23828315	Open Targets	Endocrine resistance Rap1 signaling pathway Calcium signaling pathway +58 more
		KMT2C	Unknown	32100878	Open Targets	Lysine degradation Metabolic pathways PKMTs methylate histone lysines +1 more
		KMT2D	Unknown	32100878	Open Targets	Lysine degradation Metabolic pathways Cushing syndrome +4 more
		KRAS	Unknown	24312577 26506885 32100878 23828315 27410028 8405868 26111977	Open Targets	EGFR tyrosine kinase inhibitor resistance Endocrine resistance MAPK signaling pathway +134 more
		NF1	Unknown	32100878	Open Targets	EGFR tyrosine kinase inhibitor resistance MAPK signaling pathway Ras signaling pathway +2 more
		PBRM1	Unknown	32100878	Open Targets	ATP-dependent chromatin remodeling Hepatocellular carcinoma RMTs methylate histone arginines +1 more
		PIK3CA	Unknown	32100878	Open Targets	Inositol phosphate metabolism Metabolic pathways EGFR tyrosine kinase inhibitor resistance +149 more
		RNF43	Unknown	32100878 27864998	Open Targets	Wnt signaling pathway Regulation of FZD by ubiquitination RNF mutants show enhanced WNT signaling and proliferation
		SMAD4	Unknown	32100878	Open Targets	FoxO signaling pathway Hormone signaling Cell cycle +30 more
		STK11	Unknown	32100878	Open Targets	FoxO signaling pathway Hormone signaling Autophagy - animal +9 more
		TP53	Unknown	32100878	Open Targets	Endocrine resistance Platinum drug resistance MAPK signaling pathway +85 more