Pathways column key: KEGG Reactome

Disease Term	Disease ID	Gene Symbol	Classification	References	Source	Pathways
ATTENTION DEFICIT HYPERACTIVITY DISORDER	EFO_0003888 C1263846	CYRIA	Unknown	40962958	GWAS catalog	Regulation of actin cytoskeleton
		CYSTM1	Unknown	35764056	GWAS catalog	Neutrophil degranulation
		DAB1	Unknown	34446935	GWAS catalog	Spinocerebellar ataxia Reelin signalling pathway
		DACH1	Unknown	34446935	GWAS catalog	—
		DAGLA	Unknown	—	Disgenet	Retrograde endocannabinoid signaling Aldosterone synthesis and secretion Arachidonate production from DAG
		DAGLB	Unknown	32595297	GWAS catalog	Retrograde endocannabinoid signaling Aldosterone synthesis and secretion Arachidonate production from DAG
		DBN1	Unknown	35764056	GWAS catalog	—
		DCAF4	Unknown	35764056	GWAS catalog	Neddylation
		DCAF6	Unknown	40962958	GWAS catalog	Neddylation
		DCC	Unknown	31835028 32606422 33479212 34446935 35764056 35927488 36137488 36702997 38565336 40962958	GWAS catalog	Axon guidance Pathways in cancer Colorectal cancer +3 more
		DCDC1	Unknown	34446935	GWAS catalog	—
		DDB2	Unknown	34446935	GWAS catalog	Nucleotide excision repair p53 signaling pathway Ubiquitin mediated proteolysis +23 more
		DDN	Unknown	35764056	GWAS catalog	—
		DDX27	Unknown	35764056	GWAS catalog	—
		DEFB112	Unknown	35764056	GWAS catalog	—
		DENND1A	Unknown	34446935 38565336	GWAS catalog	RAB GEFs exchange GTP for GDP on RABs
		DENND1B	Unknown	34446935	GWAS catalog	RAB GEFs exchange GTP for GDP on RABs
		DENND5B	Unknown	29325848	GWAS catalog	RAB GEFs exchange GTP for GDP on RABs
		DESI1	Unknown	35764056	GWAS catalog	—
		DGKI	Unknown	31835028 33686288	GWAS catalog	Glycerolipid metabolism Glycerophospholipid metabolism Metabolic pathways +4 more
		DHH	Unknown	33686288	GWAS catalog	Hedgehog signaling pathway Hedgehog ligand biogenesis Release of Hh-Np from the secreting cell +3 more
		DHRS11	Unknown	35764056	GWAS catalog	Steroid hormone biosynthesis
		DISP3	Unknown	32595297	GWAS catalog	—
		DLC1	Unknown	30563984 32279069	GWAS catalog	Rho GTPase cycle
		DLEU7	Unknown	32595297	GWAS catalog	—
		DLG2	Unknown	34446935	GWAS catalog	Hippo signaling pathway Tight junction Human papillomavirus infection +3 more
		DLK1	Unknown	40962958	GWAS catalog	—
		DLX6	Unknown	34446935	GWAS catalog	—
		DMAC1	Unknown	18951430	GWAS catalog	—
		DMXL2	Unknown	35764056 36738649	GWAS catalog	Lysosome
		DNAJC1	Unknown	34446935	GWAS catalog	Protein processing in endoplasmic reticulum
		DNAJC10	Unknown	34446935	GWAS catalog	Protein processing in endoplasmic reticulum
		DNAJC11	Unknown	34446935	GWAS catalog	—
		DNM1	Unknown	18839057	GWAS catalog	Phospholipase D signaling pathway Endocytosis Synaptic vesicle cycle +9 more
		DNMT3B	Unknown	23527680	GWAS catalog	Cysteine and methionine metabolism Metabolic pathways MicroRNAs in cancer +2 more
		DOCK10	Unknown	18937294 34446935	GWAS catalog	Factors involved in megakaryocyte development and platelet production
		DPF3	Unknown	35764056	GWAS catalog	ATP-dependent chromatin remodeling Thermogenesis Hepatocellular carcinoma
		DPP10	Unknown	18821565	GWAS catalog	—
		DPP4	Unknown	35764056	GWAS catalog	Virion - Hepatitis viruses Protein digestion and absorption Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) +1 more
		DPP6	Unknown	23527680	GWAS catalog	—
		DPP8	Unknown	35764056	GWAS catalog	—
		DUSP26	Unknown	38565336	GWAS catalog	—
		DUSP6	Unknown	29325848 30478444 30610198 32279069 32606422 33686288 34446935 35764056 36702997 36753304 37689771 38036780 38565336 40962958	GWAS catalog	MAPK signaling pathway Transcriptional misregulation in cancer Acute myeloid leukemia +3 more
		DYSF	Unknown	35764056	GWAS catalog	Smooth Muscle Contraction
		E2F3	Unknown	36738649	GWAS catalog	Endocrine resistance Cell cycle Cellular senescence +26 more
		EED	Unknown	34446935	GWAS catalog	Polycomb repressive complex PRC2 methylates histones and DNA Oxidative Stress Induced Senescence +4 more
		EFCAB8	Unknown	23527680	GWAS catalog	—
		EFL1	Unknown	35764056	GWAS catalog	Ribosome biogenesis in eukaryotes
		EFNA5	Unknown	34446935 35764056	GWAS catalog	MAPK signaling pathway Ras signaling pathway Rap1 signaling pathway +6 more
		EFNB1	Unknown	33479212	GWAS catalog	Axon guidance EPH-Ephrin signaling EPHB-mediated forward signaling +2 more

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Attention deficit hyperactivity disorder

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