Amyotrophic lateral sclerosis

Cytoskeleton in muscle cells

Axon guidance Sema3A PAK dependent Axon repulsion SEMA3A-Plexin repulsion signaling by inhibiting Integrin adhesion CRMPs in Sema3A signaling Other semaphorin interactions +2 more

Complement and coagulation cascades Common Pathway of Fibrin Clot Formation Cell surface interactions at the vascular wall

Endocytosis

Neuroactive ligand-receptor interaction Class B/2 (Secretin family receptors) G alpha (s) signalling events ADORA2B mediated anti-inflammatory cytokines production +1 more

G alpha (i) signalling events Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding

Gluconeogenesis Aspartate and asparagine metabolism

Sodium/Proton exchangers Defective SLC9A9 causes autism 16 (AUTS16)

Platelet degranulation Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs) Post-translational protein phosphorylation

Mucin type O-glycan biosynthesis Glycosphingolipid biosynthesis - ganglio series Metabolic pathways Sialic acid metabolism Termination of O-glycan biosynthesis +2 more

Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis

Cargo recognition for clathrin-mediated endocytosis Clathrin-mediated endocytosis

Lysosome Glycosphingolipid metabolism The activation of arylsulfatases

Cytoskeleton in muscle cells

Basal transcription factors RNA polymerase II transcribes snRNA genes

Arachidonic acid metabolism Metabolic pathways Platelet activation Eicosanoids Synthesis of Prostaglandins (PG) and Thromboxanes (TX) Defective TBXAS1 causes Ghosal hematodiaphyseal dysplasia (GHDD) +3 more

Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors Negative regulation of activity of TFAP2 (AP-2) family transcription factors TFAP2 (AP-2) family regulates transcription of other transcription factors Activation of the TFAP2 (AP-2) family of transcription factors TFAP2 (AP-2) family regulates transcription of growth factors and their receptors TFAP2 (AP-2) family regulates transcription of cell cycle factors TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation +4 more

Inflammatory mediator regulation of TRP channels TRP channels

Cell cycle Separation of Sister Chromatids Establishment of Sister Chromatid Cohesion Cohesin Loading onto Chromatin Resolution of Sister Chromatid Cohesion +2 more