Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9904
Gene name Gene Name - the full gene name approved by the HGNC.
RNA binding motif protein 19
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
RBM19
Synonyms (NCBI Gene) Gene synonyms aliases
Mrd1
Chromosome Chromosome number
12
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
12q24.13-q24.21
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a nucleolar protein that contains six RNA-binding motifs. The encoded protein may be involved in regulating ribosome biogenesis. Multiple alternatively spliced variants, encoding the same protein, have been identified.[provided by RefSeq
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT001601 hsa-let-7b-5p pSILAC 18668040
MIRT027657 hsa-miR-98-5p Microarray 19088304
MIRT029422 hsa-miR-26b-5p Microarray 19088304
MIRT001601 hsa-let-7b-5p Proteomics;Other 18668040
MIRT1295156 hsa-miR-1262 CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000398 Process MRNA splicing, via spliceosome IBA 21873635
GO:0003723 Function RNA binding HDA 22658674, 22681889
GO:0003723 Function RNA binding IBA 21873635
GO:0005654 Component Nucleoplasm ISS
GO:0005694 Component Chromosome IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
616444 29098 ENSG00000122965
Protein
UniProt ID Q9Y4C8
Protein name Probable RNA-binding protein 19 (RNA-binding motif protein 19)
Protein function Plays a role in embryo pre-implantation development.
PDB 2DGW
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00076 RRM_1 4 73 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF00076 RRM_1 296 363 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF00076 RRM_1 404 474 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF00076 RRM_1 589 653 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF00076 RRM_1 732 805 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
PF00076 RRM_1 834 906 RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain) Domain
Tissue specificity TISSUE SPECIFICITY: Expressed in the crypts of Lieberkuhn of the intestine and in intestinal neoplasia (at protein level). {ECO:0000269|PubMed:16027046}.
Sequence
MSRLIVKNLPNGMKEERFRQLFAAFGTLTDCSLKFTKDGKFRKFGFIGFKSEEEAQKAQK
HFNKSFIDTSRIT
VEFCKSFGDPAKPRAWSKHAQKPSQPKQPPKDSTTPEIKKDEKKKKV
AGQLEKLKEDTEFQEFLSVHQRRAQAATWANDGLDAEPSKGKSKPASDYLNFDSDSGQES
EEEGAGEDLEEEASLEPKAAVQKELSDMDYLKSKMVKAGSSSSSEEEESEDEAVHCDEGS
EAEEEDSSATPVLQERDSKGAGQEQGMPAGKKRPPEARAETEKPANQKEPTTCHTVKLRG
APFNVTEKNVMEFLAPLKPVAIRIVRNAHGNKTGYIFVDFSNEEEVKQALKCNREYMGGR
YIE
VFREKNVPTTKGAPKNTTKSWQGRILGENEEEEDLAESGRLFVRNLPYTSTEEDLEK
LFSKYGPLSELHYPIDSLTKKPKGFAFITFMFPEHAVKAYSEVDGQVFQGRMLH
VLPSTI
KKEASEDASALGSSSYKKKKEAQDKANSASSHNWNTLFMGPNAVADAIAQKYNATKSQVF
DHETKGSVAVRVALGETQLVQEVRRFLIDNGVSLDSFSQAAAERSKTVILVKNLPAGTLA
AQLQETFGHFGSLGRVLLPEGGITAIVEFLEPLEARKAFRHLAYSKFHHVPLY
LEWAPVG
VFSSTAPQKKKLQDTPSEPMEKDPAEPETVPDGETPEDENPTEEGADNSSAKMEEEEEEE
EEEEESLPGCTLFIKNLNFDTTEEKLKEVFSKVGTVKSCSISKKKNKAGVLLSMGFGFVE
YRKPEQAQKALKQLQGHVVDGHKLE
VRISERATKPAVTLARKKQVPRKQTTSKILVRNIP
FQAHSREIRELFSTFGELKTVRLPKKMTGTGTHRGFGFVDFLTKQDAKRAFNALCHSTHL
YGRRLV
LEWADSEVTLQALRRKTAAHFHEPPKKKRSVVLDEILEQLEGSDSDSEEQTLQL
Sequence length 960
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Diabetes mellitus Diabetes Mellitus, Non-Insulin-Dependent rs587776515, rs61730328, rs606231121, rs606231122, rs79020217, rs77625743, rs78378398, rs606231123, rs1362648752, rs104893649, rs80356624, rs80356616, rs80356625, rs80356611, rs104894237
View all (293 more)
28736931
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 33411682
Ermine phenotype Associate 26449790
Inflammatory Bowel Diseases Associate 26449790
Pulmonary Disease Chronic Obstructive Associate 26423011