Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9679
Gene name Gene Name - the full gene name approved by the HGNC.
Family with sequence similarity 53 member B
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
FAM53B
Synonyms (NCBI Gene) Gene synonyms aliases
KIAA0140, bA12J10.2, smp
Chromosome Chromosome number
10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
10q26.13
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT039635 hsa-miR-615-3p CLASH 23622248
MIRT614181 hsa-miR-548c-3p HITS-CLIP 23824327
MIRT614180 hsa-miR-6515-3p HITS-CLIP 23824327
MIRT614179 hsa-miR-1236-3p HITS-CLIP 23824327
MIRT614178 hsa-miR-130b-5p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005634 Component Nucleus IBA 21873635
GO:0005634 Component Nucleus IDA 25183871
GO:0006606 Process Protein import into nucleus IBA 21873635
GO:0016055 Process Wnt signaling pathway IEA
GO:0060828 Process Regulation of canonical Wnt signaling pathway IMP 25183871
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
617289 28968 ENSG00000189319
Protein
UniProt ID Q14153
Protein name Protein FAM53B (Protein simplet)
Protein function Acts as a regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) nuclear localization.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15242 FAM53 1 302 Family of FAM53 Family
Tissue specificity TISSUE SPECIFICITY: Detected in skeletal muscle, kidney, spleen, thyroid, testis, ovary, small intestine, colon and peripheral blood. {ECO:0000269|PubMed:8590280}.
Sequence
Sequence length 422
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Gout Gout GWAS
Lung adenocarcinoma Lung adenocarcinoma Validation that loss of Tgfbr2 results in more aggressive and T cell-excluded KP lung tumors GWAS, CBGDA
Associations from Text Mining
Disease Name Relationship Type References
Cocaine Related Disorders Associate 23958962
Neoplasms Associate 21955603
Paranoid Disorders Associate 23958962
Tertiary Lymphoid Structures Associate 21955603