Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9678
Gene name Gene Name - the full gene name approved by the HGNC.
PHD finger protein 14
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PHF14
Synonyms (NCBI Gene) Gene synonyms aliases
-
Chromosome Chromosome number
7
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
7p21.3
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT020981 hsa-miR-155-5p Reporter assay;Other 20584899
MIRT022055 hsa-miR-128-3p Microarray 17612493
MIRT023375 hsa-miR-122-5p Microarray 17612493
MIRT047036 hsa-miR-183-5p CLASH 23622248
MIRT444900 hsa-miR-200b-3p PAR-CLIP 22291592
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000122 Process Negative regulation of transcription by RNA polymerase II IEA
GO:0000122 Process Negative regulation of transcription by RNA polymerase II ISS
GO:0000785 Component Chromatin IDA 23688586
GO:0002314 Process Germinal center B cell differentiation IEA
GO:0002314 Process Germinal center B cell differentiation ISS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
619907 22203 ENSG00000106443
Protein
UniProt ID O94880
Protein name PHD finger protein 14
Protein function Histone-binding protein (PubMed:23688586). Binds preferentially to unmodified histone H3 but can also bind to a lesser extent to histone H3 trimethylated at 'Lys-9' (H3K9me3) as well as to histone H3 monomethylated at 'Lys-27' (H3K27ac) and trim
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00628 PHD 321 380 PHD-finger Domain
PF13832 zf-HC5HC2H_2 383 498 Domain
PF00628 PHD 727 779 PHD-finger Domain
Sequence
MDRSSKRRQVKPLAASLLEALDYDSSDDSDFKVGDASDSEGSGNGSEDASKDSGEGSCSD
SEENILEEELNEDIKVKEEQLKNSAEEEVLSSEKQLIKMEKKEEEENGERPRKKKEKEKE
KEKEKEKEKEREKEKEKATVSENVAASAAATTPATSPPAVNTSPSVPTTTTATEEQVSEP
KKWNLRRNRPLLDFVSMEELNDMDDYDSEDDNDWRPTVVKRKGRSASQKEGSDGDNEDDE
DEGSGSDEDENDEGNDEDHSSPASEGGCKKKKSKVLSRNSADDEELTNDSLTLSQSKSNE
DSLILEKSQNWSSQKMDHILICCVCLGDNSEDADEIIQCDNCGITVHEGCYGVDGESDSI
MSSASENSTEPWFCDACKCG
VSPSCELCPNQDGIFKETDAGRWVHIVCALYVPGVAFGDI
DKLRPVTLTEMNYSKYGAKECSFCEDPRFARTGVCISCDAGMCRAYFHVTCAQKEGLLSE
AAAEEDIADPFFAYCKQH
ADRLDRKWKRKNYLALQSYCKMSLQEREKQLSPEAQARINAR
LQQYRAKAELARSTRPQAWVPREKLPRPLTSSASAIRKLMRKAELMGISTDIFPVDNSDT
SSSVDGRRKHKQPALTADFVNYYFERNMRMIQIQENMAEQKNIKDKLENEQEKLHVEYNK
LCESLEELQNLNGKLRSEGQGIWALLGRITGQKLNIPAILRAPKERKPSKKEGGTQKTST
LPAVLYSCGICKKNHDQHLLLLCDTCKLHYHLGCLDPPLTRMPRKTKNSYWQCSECDQAG
SSDMEADMAMETLPDGTKRSRRQIKEPVKFVPQDVPPEPKKIPIRNTRTRGRKRSFVPEE
EKHEERVPRERRQRQSVLQKKPKAEDLRTECATCKGTGDNENLVRYPS
Sequence length 888
Interactions View interactions
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Associated diseases Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Disease merge term Disease name Evidence References Source
Asthma Self-reported childhood asthma in adult smokers N/A N/A GWAS
Breast Cancer Breast cancer specific mortality in breast cancer N/A N/A GWAS
Insomnia Insomnia N/A N/A GWAS
Prostate cancer Prostate cancer N/A N/A GWAS
Associations from Text Mining Disease associations identified through Pubtator
Disease Name Relationship Type References
Atherosclerosis Associate 30915882
Congenital Abnormalities Associate 28814329
Esophageal Squamous Cell Carcinoma Associate 37768180
Hypertension Associate 26866982
Hypertension Pulmonary Associate 28814329
Lung Diseases Associate 30915882
Respiratory Insufficiency Associate 28814329