Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	9616
Gene name Gene Name - the full gene name approved by the HGNC.	Ring finger protein 7
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	RNF7
Synonyms (NCBI Gene) Gene synonyms aliases	CKBBP1, ROC2, SAG, rbx2
Chromosome Chromosome number	3
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	3q23
Summary Summary of gene provided in NCBI Entrez Gene.	The protein encoded by this gene is a highly conserved ring finger protein. It is an essential subunit of SKP1-cullin/CDC53-F box protein ubiquitin ligases, which are a part of the protein degradation machinery important for cell cycle progression and sig

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miRTarBase ID	miRNA	Experiments	Reference
MIRT019231	hsa-miR-331-3p	Sequencing	20371350
MIRT439146	hsa-let-7c-5p	3'LIFE	25074381
MIRT439146	hsa-let-7c-5p	3'LIFE	25074381
MIRT1313647	hsa-miR-1183	CLIP-seq
MIRT1313648	hsa-miR-1293	CLIP-seq
MIRT1313649	hsa-miR-1827	CLIP-seq
MIRT1313650	hsa-miR-2110	CLIP-seq
MIRT1313651	hsa-miR-34b	CLIP-seq
MIRT1313652	hsa-miR-3614-5p	CLIP-seq
MIRT1313653	hsa-miR-3622a-3p	CLIP-seq
MIRT1313654	hsa-miR-3622b-3p	CLIP-seq
MIRT1313655	hsa-miR-3672	CLIP-seq
MIRT1313656	hsa-miR-3926	CLIP-seq
MIRT1313657	hsa-miR-3929	CLIP-seq
MIRT1313658	hsa-miR-4271	CLIP-seq
MIRT1313659	hsa-miR-4325	CLIP-seq
MIRT1313660	hsa-miR-4419b	CLIP-seq
MIRT1313661	hsa-miR-4433	CLIP-seq
MIRT1313662	hsa-miR-4459	CLIP-seq
MIRT1313663	hsa-miR-4478	CLIP-seq
MIRT1313664	hsa-miR-4483	CLIP-seq
MIRT1313665	hsa-miR-451b	CLIP-seq
MIRT1313666	hsa-miR-4649-3p	CLIP-seq
MIRT1313667	hsa-miR-4649-5p	CLIP-seq
MIRT1313668	hsa-miR-4693-5p	CLIP-seq
MIRT1313669	hsa-miR-4722-5p	CLIP-seq
MIRT1313670	hsa-miR-4725-3p	CLIP-seq
MIRT1313671	hsa-miR-4768-3p	CLIP-seq
MIRT1313672	hsa-miR-4786-5p	CLIP-seq
MIRT1313673	hsa-miR-4793-3p	CLIP-seq
MIRT1313674	hsa-miR-485-5p	CLIP-seq
MIRT1313675	hsa-miR-508-5p	CLIP-seq
MIRT1313676	hsa-miR-544b	CLIP-seq
MIRT1313677	hsa-miR-548g	CLIP-seq
MIRT1313678	hsa-miR-548s	CLIP-seq
MIRT1313679	hsa-miR-605	CLIP-seq
MIRT1313680	hsa-miR-658	CLIP-seq
MIRT1313681	hsa-miR-661	CLIP-seq
MIRT1313682	hsa-miR-766	CLIP-seq
MIRT1313683	hsa-miR-769-5p	CLIP-seq
MIRT1313684	hsa-miR-940	CLIP-seq
MIRT1313685	hsa-let-7a	CLIP-seq
MIRT1313686	hsa-let-7b	CLIP-seq
MIRT1313687	hsa-let-7c	CLIP-seq
MIRT1313688	hsa-let-7d	CLIP-seq
MIRT1313689	hsa-let-7e	CLIP-seq
MIRT1313690	hsa-let-7f	CLIP-seq
MIRT1313691	hsa-let-7g	CLIP-seq
MIRT1313692	hsa-let-7i	CLIP-seq
MIRT1313647	hsa-miR-1183	CLIP-seq
MIRT1313693	hsa-miR-1228	CLIP-seq
MIRT1313694	hsa-miR-1243	CLIP-seq
MIRT1313695	hsa-miR-140-3p	CLIP-seq
MIRT1313696	hsa-miR-142-3p	CLIP-seq
MIRT1313649	hsa-miR-1827	CLIP-seq
MIRT1313697	hsa-miR-194	CLIP-seq
MIRT1313698	hsa-miR-3143	CLIP-seq
MIRT1313699	hsa-miR-3174	CLIP-seq
MIRT1313700	hsa-miR-3185	CLIP-seq
MIRT1313701	hsa-miR-329	CLIP-seq
MIRT1313651	hsa-miR-34b	CLIP-seq
MIRT1313702	hsa-miR-3614-3p	CLIP-seq
MIRT1313652	hsa-miR-3614-5p	CLIP-seq
MIRT1313653	hsa-miR-3622a-3p	CLIP-seq
MIRT1313654	hsa-miR-3622b-3p	CLIP-seq
MIRT1313703	hsa-miR-362-3p	CLIP-seq
MIRT1313704	hsa-miR-3653	CLIP-seq
MIRT1313705	hsa-miR-3674	CLIP-seq
MIRT1313657	hsa-miR-3929	CLIP-seq
MIRT1313706	hsa-miR-3940-5p	CLIP-seq
MIRT1313707	hsa-miR-4255	CLIP-seq
MIRT1313708	hsa-miR-4257	CLIP-seq
MIRT1313709	hsa-miR-4259	CLIP-seq
MIRT1313659	hsa-miR-4325	CLIP-seq
MIRT1313660	hsa-miR-4419b	CLIP-seq
MIRT1313661	hsa-miR-4433	CLIP-seq
MIRT1313710	hsa-miR-4436b-3p	CLIP-seq
MIRT1313711	hsa-miR-4455	CLIP-seq
MIRT1313712	hsa-miR-4458	CLIP-seq
MIRT1313662	hsa-miR-4459	CLIP-seq
MIRT1313713	hsa-miR-4476	CLIP-seq
MIRT1313663	hsa-miR-4478	CLIP-seq
MIRT1313714	hsa-miR-4500	CLIP-seq
MIRT1313715	hsa-miR-4507	CLIP-seq
MIRT1313716	hsa-miR-4533	CLIP-seq
MIRT1313717	hsa-miR-4539	CLIP-seq
MIRT1313666	hsa-miR-4649-3p	CLIP-seq
MIRT1313667	hsa-miR-4649-5p	CLIP-seq
MIRT1313718	hsa-miR-4685-5p	CLIP-seq
MIRT1313668	hsa-miR-4693-5p	CLIP-seq
MIRT1313719	hsa-miR-4709-3p	CLIP-seq
MIRT1313669	hsa-miR-4722-5p	CLIP-seq
MIRT1313720	hsa-miR-4733-3p	CLIP-seq
MIRT1313721	hsa-miR-4760-3p	CLIP-seq
MIRT1313722	hsa-miR-4761-3p	CLIP-seq
MIRT1313671	hsa-miR-4768-3p	CLIP-seq
MIRT1313673	hsa-miR-4793-3p	CLIP-seq
MIRT1313674	hsa-miR-485-5p	CLIP-seq
MIRT1313723	hsa-miR-543	CLIP-seq
MIRT1313676	hsa-miR-544b	CLIP-seq
MIRT1313677	hsa-miR-548g	CLIP-seq
MIRT1313724	hsa-miR-629	CLIP-seq
MIRT1313680	hsa-miR-658	CLIP-seq
MIRT1313725	hsa-miR-760	CLIP-seq
MIRT1313684	hsa-miR-940	CLIP-seq
MIRT1313726	hsa-miR-98	CLIP-seq
MIRT1313693	hsa-miR-1228	CLIP-seq
MIRT1313648	hsa-miR-1293	CLIP-seq
MIRT1313695	hsa-miR-140-3p	CLIP-seq
MIRT1313649	hsa-miR-1827	CLIP-seq
MIRT1313699	hsa-miR-3174	CLIP-seq
MIRT1313701	hsa-miR-329	CLIP-seq
MIRT1313651	hsa-miR-34b	CLIP-seq
MIRT1313652	hsa-miR-3614-5p	CLIP-seq
MIRT1313703	hsa-miR-362-3p	CLIP-seq
MIRT1313657	hsa-miR-3929	CLIP-seq
MIRT1313706	hsa-miR-3940-5p	CLIP-seq
MIRT2093383	hsa-miR-4252	CLIP-seq
MIRT1313709	hsa-miR-4259	CLIP-seq
MIRT2093384	hsa-miR-4263	CLIP-seq
MIRT1313660	hsa-miR-4419b	CLIP-seq
MIRT1313711	hsa-miR-4455	CLIP-seq
MIRT1313663	hsa-miR-4478	CLIP-seq
MIRT1313664	hsa-miR-4483	CLIP-seq
MIRT1313715	hsa-miR-4507	CLIP-seq
MIRT1313665	hsa-miR-451b	CLIP-seq
MIRT1313666	hsa-miR-4649-3p	CLIP-seq
MIRT2093385	hsa-miR-4696	CLIP-seq
MIRT1313669	hsa-miR-4722-5p	CLIP-seq
MIRT1313721	hsa-miR-4760-3p	CLIP-seq
MIRT2093386	hsa-miR-4760-5p	CLIP-seq
MIRT1313671	hsa-miR-4768-3p	CLIP-seq
MIRT1313673	hsa-miR-4793-3p	CLIP-seq
MIRT1313674	hsa-miR-485-5p	CLIP-seq
MIRT1313675	hsa-miR-508-5p	CLIP-seq
MIRT2093387	hsa-miR-571	CLIP-seq
MIRT1313724	hsa-miR-629	CLIP-seq
MIRT1313680	hsa-miR-658	CLIP-seq
MIRT1313681	hsa-miR-661	CLIP-seq
MIRT1313682	hsa-miR-766	CLIP-seq
MIRT1313684	hsa-miR-940	CLIP-seq
MIRT2317908	hsa-miR-3913-3p	CLIP-seq
MIRT2093384	hsa-miR-4263	CLIP-seq
MIRT2317909	hsa-miR-489	CLIP-seq
MIRT2093387	hsa-miR-571	CLIP-seq
MIRT1313685	hsa-let-7a	CLIP-seq
MIRT1313686	hsa-let-7b	CLIP-seq
MIRT1313687	hsa-let-7c	CLIP-seq
MIRT1313688	hsa-let-7d	CLIP-seq
MIRT1313689	hsa-let-7e	CLIP-seq
MIRT1313690	hsa-let-7f	CLIP-seq
MIRT1313691	hsa-let-7g	CLIP-seq
MIRT1313692	hsa-let-7i	CLIP-seq
MIRT2317910	hsa-miR-1247	CLIP-seq
MIRT1313648	hsa-miR-1293	CLIP-seq
MIRT1313695	hsa-miR-140-3p	CLIP-seq
MIRT1313649	hsa-miR-1827	CLIP-seq
MIRT1313650	hsa-miR-2110	CLIP-seq
MIRT2317911	hsa-miR-3122	CLIP-seq
MIRT1313699	hsa-miR-3174	CLIP-seq
MIRT1313701	hsa-miR-329	CLIP-seq
MIRT1313651	hsa-miR-34b	CLIP-seq
MIRT1313652	hsa-miR-3614-5p	CLIP-seq
MIRT1313703	hsa-miR-362-3p	CLIP-seq
MIRT2317912	hsa-miR-3689a-3p	CLIP-seq
MIRT2317913	hsa-miR-3689c	CLIP-seq
MIRT2317914	hsa-miR-3913-5p	CLIP-seq
MIRT1313656	hsa-miR-3926	CLIP-seq
MIRT1313657	hsa-miR-3929	CLIP-seq
MIRT2093383	hsa-miR-4252	CLIP-seq
MIRT1313708	hsa-miR-4257	CLIP-seq
MIRT2093384	hsa-miR-4263	CLIP-seq
MIRT1313658	hsa-miR-4271	CLIP-seq
MIRT1313660	hsa-miR-4419b	CLIP-seq
MIRT1313711	hsa-miR-4455	CLIP-seq
MIRT1313712	hsa-miR-4458	CLIP-seq
MIRT1313713	hsa-miR-4476	CLIP-seq
MIRT1313663	hsa-miR-4478	CLIP-seq
MIRT1313664	hsa-miR-4483	CLIP-seq
MIRT1313714	hsa-miR-4500	CLIP-seq
MIRT1313716	hsa-miR-4533	CLIP-seq
MIRT1313666	hsa-miR-4649-3p	CLIP-seq
MIRT1313667	hsa-miR-4649-5p	CLIP-seq
MIRT2317915	hsa-miR-4684-5p	CLIP-seq
MIRT1313669	hsa-miR-4722-5p	CLIP-seq
MIRT1313670	hsa-miR-4725-3p	CLIP-seq
MIRT2317916	hsa-miR-4728-5p	CLIP-seq
MIRT1313671	hsa-miR-4768-3p	CLIP-seq
MIRT1313672	hsa-miR-4786-5p	CLIP-seq
MIRT1313673	hsa-miR-4793-3p	CLIP-seq
MIRT1313674	hsa-miR-485-5p	CLIP-seq
MIRT1313675	hsa-miR-508-5p	CLIP-seq
MIRT2317917	hsa-miR-541	CLIP-seq
MIRT1313678	hsa-miR-548s	CLIP-seq
MIRT2093387	hsa-miR-571	CLIP-seq
MIRT1313679	hsa-miR-605	CLIP-seq
MIRT2317918	hsa-miR-654-5p	CLIP-seq
MIRT1313680	hsa-miR-658	CLIP-seq
MIRT1313681	hsa-miR-661	CLIP-seq
MIRT1313682	hsa-miR-766	CLIP-seq
MIRT1313683	hsa-miR-769-5p	CLIP-seq
MIRT2317919	hsa-miR-933	CLIP-seq
MIRT1313684	hsa-miR-940	CLIP-seq
MIRT1313726	hsa-miR-98	CLIP-seq
MIRT1313693	hsa-miR-1228	CLIP-seq
MIRT1313694	hsa-miR-1243	CLIP-seq
MIRT2317910	hsa-miR-1247	CLIP-seq
MIRT1313648	hsa-miR-1293	CLIP-seq
MIRT1313695	hsa-miR-140-3p	CLIP-seq
MIRT1313696	hsa-miR-142-3p	CLIP-seq
MIRT2613569	hsa-miR-142-5p	CLIP-seq
MIRT1313649	hsa-miR-1827	CLIP-seq
MIRT1313650	hsa-miR-2110	CLIP-seq
MIRT2613570	hsa-miR-2115	CLIP-seq
MIRT2613571	hsa-miR-219-1-3p	CLIP-seq
MIRT2613572	hsa-miR-3074-3p	CLIP-seq
MIRT2317911	hsa-miR-3122	CLIP-seq
MIRT2613573	hsa-miR-3124-3p	CLIP-seq
MIRT2613574	hsa-miR-3136-3p	CLIP-seq
MIRT1313699	hsa-miR-3174	CLIP-seq
MIRT1313700	hsa-miR-3185	CLIP-seq
MIRT2613575	hsa-miR-320e	CLIP-seq
MIRT1313701	hsa-miR-329	CLIP-seq
MIRT2613576	hsa-miR-340	CLIP-seq
MIRT1313651	hsa-miR-34b	CLIP-seq
MIRT2613577	hsa-miR-3613-5p	CLIP-seq
MIRT1313702	hsa-miR-3614-3p	CLIP-seq
MIRT1313652	hsa-miR-3614-5p	CLIP-seq
MIRT1313653	hsa-miR-3622a-3p	CLIP-seq
MIRT1313654	hsa-miR-3622b-3p	CLIP-seq
MIRT1313703	hsa-miR-362-3p	CLIP-seq
MIRT1313704	hsa-miR-3653	CLIP-seq
MIRT1313655	hsa-miR-3672	CLIP-seq
MIRT1313705	hsa-miR-3674	CLIP-seq
MIRT2317912	hsa-miR-3689a-3p	CLIP-seq
MIRT2317913	hsa-miR-3689c	CLIP-seq
MIRT2317914	hsa-miR-3913-5p	CLIP-seq
MIRT1313656	hsa-miR-3926	CLIP-seq
MIRT1313657	hsa-miR-3929	CLIP-seq
MIRT2093383	hsa-miR-4252	CLIP-seq
MIRT1313707	hsa-miR-4255	CLIP-seq
MIRT2093384	hsa-miR-4263	CLIP-seq
MIRT1313658	hsa-miR-4271	CLIP-seq
MIRT2613578	hsa-miR-4287	CLIP-seq
MIRT1313660	hsa-miR-4419b	CLIP-seq
MIRT1313661	hsa-miR-4433	CLIP-seq
MIRT1313710	hsa-miR-4436b-3p	CLIP-seq
MIRT2613579	hsa-miR-4436b-5p	CLIP-seq
MIRT1313711	hsa-miR-4455	CLIP-seq
MIRT1313662	hsa-miR-4459	CLIP-seq
MIRT2613580	hsa-miR-4469	CLIP-seq
MIRT1313663	hsa-miR-4478	CLIP-seq
MIRT1313664	hsa-miR-4483	CLIP-seq
MIRT2613581	hsa-miR-4484	CLIP-seq
MIRT2613582	hsa-miR-4506	CLIP-seq
MIRT1313665	hsa-miR-451b	CLIP-seq
MIRT1313717	hsa-miR-4539	CLIP-seq
MIRT2613583	hsa-miR-4633-3p	CLIP-seq
MIRT1313667	hsa-miR-4649-5p	CLIP-seq
MIRT2613584	hsa-miR-4668-3p	CLIP-seq
MIRT2317915	hsa-miR-4684-5p	CLIP-seq
MIRT2613585	hsa-miR-4685-3p	CLIP-seq
MIRT1313718	hsa-miR-4685-5p	CLIP-seq
MIRT2093385	hsa-miR-4696	CLIP-seq
MIRT2613586	hsa-miR-4698	CLIP-seq
MIRT1313719	hsa-miR-4709-3p	CLIP-seq
MIRT2613587	hsa-miR-4722-3p	CLIP-seq
MIRT1313669	hsa-miR-4722-5p	CLIP-seq
MIRT1313670	hsa-miR-4725-3p	CLIP-seq
MIRT2317916	hsa-miR-4728-5p	CLIP-seq
MIRT1313720	hsa-miR-4733-3p	CLIP-seq
MIRT2613588	hsa-miR-4738-3p	CLIP-seq
MIRT1313721	hsa-miR-4760-3p	CLIP-seq
MIRT1313722	hsa-miR-4761-3p	CLIP-seq
MIRT1313671	hsa-miR-4768-3p	CLIP-seq
MIRT1313672	hsa-miR-4786-5p	CLIP-seq
MIRT1313673	hsa-miR-4793-3p	CLIP-seq
MIRT1313674	hsa-miR-485-5p	CLIP-seq
MIRT2613589	hsa-miR-490-5p	CLIP-seq
MIRT2613590	hsa-miR-500a	CLIP-seq
MIRT1313675	hsa-miR-508-5p	CLIP-seq
MIRT2613591	hsa-miR-516a-3p	CLIP-seq
MIRT2317917	hsa-miR-541	CLIP-seq
MIRT1313676	hsa-miR-544b	CLIP-seq
MIRT2613592	hsa-miR-548an	CLIP-seq
MIRT2613593	hsa-miR-548c-3p	CLIP-seq
MIRT2613594	hsa-miR-548m	CLIP-seq
MIRT1313678	hsa-miR-548s	CLIP-seq
MIRT2613595	hsa-miR-555	CLIP-seq
MIRT2613596	hsa-miR-568	CLIP-seq
MIRT2093387	hsa-miR-571	CLIP-seq
MIRT1313679	hsa-miR-605	CLIP-seq
MIRT2613597	hsa-miR-642a	CLIP-seq
MIRT2317918	hsa-miR-654-5p	CLIP-seq
MIRT1313680	hsa-miR-658	CLIP-seq
MIRT1313681	hsa-miR-661	CLIP-seq
MIRT1313725	hsa-miR-760	CLIP-seq
MIRT1313682	hsa-miR-766	CLIP-seq
MIRT1313683	hsa-miR-769-5p	CLIP-seq
MIRT2613598	hsa-miR-802	CLIP-seq
MIRT2317919	hsa-miR-933	CLIP-seq
MIRT1313684	hsa-miR-940	CLIP-seq
MIRT1313693	hsa-miR-1228	CLIP-seq
MIRT1313694	hsa-miR-1243	CLIP-seq
MIRT2317910	hsa-miR-1247	CLIP-seq
MIRT1313648	hsa-miR-1293	CLIP-seq
MIRT1313695	hsa-miR-140-3p	CLIP-seq
MIRT1313696	hsa-miR-142-3p	CLIP-seq
MIRT2613569	hsa-miR-142-5p	CLIP-seq
MIRT1313649	hsa-miR-1827	CLIP-seq
MIRT1313650	hsa-miR-2110	CLIP-seq
MIRT2613570	hsa-miR-2115	CLIP-seq
MIRT2613571	hsa-miR-219-1-3p	CLIP-seq
MIRT2317911	hsa-miR-3122	CLIP-seq
MIRT2613573	hsa-miR-3124-3p	CLIP-seq
MIRT1313699	hsa-miR-3174	CLIP-seq
MIRT1313700	hsa-miR-3185	CLIP-seq
MIRT2613575	hsa-miR-320e	CLIP-seq
MIRT1313701	hsa-miR-329	CLIP-seq
MIRT2613576	hsa-miR-340	CLIP-seq
MIRT1313651	hsa-miR-34b	CLIP-seq
MIRT2613577	hsa-miR-3613-5p	CLIP-seq
MIRT1313702	hsa-miR-3614-3p	CLIP-seq
MIRT1313652	hsa-miR-3614-5p	CLIP-seq
MIRT1313653	hsa-miR-3622a-3p	CLIP-seq
MIRT1313654	hsa-miR-3622b-3p	CLIP-seq
MIRT1313703	hsa-miR-362-3p	CLIP-seq
MIRT1313655	hsa-miR-3672	CLIP-seq
MIRT1313705	hsa-miR-3674	CLIP-seq
MIRT2317912	hsa-miR-3689a-3p	CLIP-seq
MIRT2317913	hsa-miR-3689c	CLIP-seq
MIRT2317914	hsa-miR-3913-5p	CLIP-seq
MIRT1313656	hsa-miR-3926	CLIP-seq
MIRT1313657	hsa-miR-3929	CLIP-seq
MIRT2093383	hsa-miR-4252	CLIP-seq
MIRT1313707	hsa-miR-4255	CLIP-seq
MIRT2093384	hsa-miR-4263	CLIP-seq
MIRT1313658	hsa-miR-4271	CLIP-seq
MIRT1313660	hsa-miR-4419b	CLIP-seq
MIRT1313661	hsa-miR-4433	CLIP-seq
MIRT1313710	hsa-miR-4436b-3p	CLIP-seq
MIRT2613579	hsa-miR-4436b-5p	CLIP-seq
MIRT1313711	hsa-miR-4455	CLIP-seq
MIRT1313662	hsa-miR-4459	CLIP-seq
MIRT1313663	hsa-miR-4478	CLIP-seq
MIRT1313664	hsa-miR-4483	CLIP-seq
MIRT2613582	hsa-miR-4506	CLIP-seq
MIRT1313665	hsa-miR-451b	CLIP-seq
MIRT1313717	hsa-miR-4539	CLIP-seq
MIRT2613583	hsa-miR-4633-3p	CLIP-seq
MIRT1313667	hsa-miR-4649-5p	CLIP-seq
MIRT2317915	hsa-miR-4684-5p	CLIP-seq
MIRT1313718	hsa-miR-4685-5p	CLIP-seq
MIRT2093385	hsa-miR-4696	CLIP-seq
MIRT2613586	hsa-miR-4698	CLIP-seq
MIRT1313719	hsa-miR-4709-3p	CLIP-seq
MIRT1313669	hsa-miR-4722-5p	CLIP-seq
MIRT1313670	hsa-miR-4725-3p	CLIP-seq
MIRT2317916	hsa-miR-4728-5p	CLIP-seq
MIRT1313720	hsa-miR-4733-3p	CLIP-seq
MIRT2613588	hsa-miR-4738-3p	CLIP-seq
MIRT1313721	hsa-miR-4760-3p	CLIP-seq
MIRT1313722	hsa-miR-4761-3p	CLIP-seq
MIRT1313671	hsa-miR-4768-3p	CLIP-seq
MIRT1313672	hsa-miR-4786-5p	CLIP-seq
MIRT1313673	hsa-miR-4793-3p	CLIP-seq
MIRT1313674	hsa-miR-485-5p	CLIP-seq
MIRT1313675	hsa-miR-508-5p	CLIP-seq
MIRT2613591	hsa-miR-516a-3p	CLIP-seq
MIRT2317917	hsa-miR-541	CLIP-seq
MIRT1313676	hsa-miR-544b	CLIP-seq
MIRT2613593	hsa-miR-548c-3p	CLIP-seq
MIRT2613594	hsa-miR-548m	CLIP-seq
MIRT1313678	hsa-miR-548s	CLIP-seq
MIRT2613595	hsa-miR-555	CLIP-seq
MIRT2613596	hsa-miR-568	CLIP-seq
MIRT2093387	hsa-miR-571	CLIP-seq
MIRT1313679	hsa-miR-605	CLIP-seq
MIRT2317918	hsa-miR-654-5p	CLIP-seq
MIRT1313680	hsa-miR-658	CLIP-seq
MIRT1313681	hsa-miR-661	CLIP-seq
MIRT1313725	hsa-miR-760	CLIP-seq
MIRT1313682	hsa-miR-766	CLIP-seq
MIRT1313683	hsa-miR-769-5p	CLIP-seq
MIRT2317919	hsa-miR-933	CLIP-seq
MIRT1313684	hsa-miR-940	CLIP-seq

Transcription factors

Show/Hide all(1)

Transcription factor	Regulation	Reference
NR4A1	Repression	22159226

Show/Hide all(24)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005507	Function	Copper ion binding	TAS	10082581
GO:0005515	Function	Protein binding	IPI	16325183, 19250909, 20098747, 21145461, 21516116, 22190034, 25416956, 26030842, 26906416, 32296183
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005634	Component	Nucleus	NAS	10082581
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	NAS	10082581
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IBA	21873635
GO:0008270	Function	Zinc ion binding	IEA
GO:0016567	Process	Protein ubiquitination	IBA	21873635
GO:0016567	Process	Protein ubiquitination	IEA
GO:0018215	Process	Protein phosphopantetheinylation	IEA
GO:0019788	Function	NEDD8 transferase activity	TAS
GO:0031461	Component	Cullin-RING ubiquitin ligase complex	IBA	21873635
GO:0031466	Component	Cul5-RING ubiquitin ligase complex	IBA	21873635
GO:0031466	Component	Cul5-RING ubiquitin ligase complex	IDA	22405651
GO:0043687	Process	Post-translational protein modification	TAS
GO:0045116	Process	Protein neddylation	IDA	19250909
GO:0051775	Process	Response to redox state	TAS	10082581
GO:0061630	Function	Ubiquitin protein ligase activity	IBA	21873635
GO:0061663	Function	NEDD8 ligase activity	IDA	19250909
GO:0097602	Function	Cullin family protein binding	IBA	21873635
GO:0097602	Function	Cullin family protein binding	IDA	10230407

MIM	HGNC	e!Ensembl
603863	10070	ENSG00000114125

Protein

UniProt ID

Q9UBF6

Protein name

RING-box protein 2 (Rbx2) (EC 2.3.2.27) (EC 2.3.2.32) (CKII beta-binding protein 1) (CKBBP1) (RING finger protein 7) (Regulator of cullins 2) (Sensitive to apoptosis gene protein)

Protein function

Catalytic component of multiple cullin-5-RING E3 ubiquitin-protein ligase complexes (ECS complexes), which mediate the ubiquitination and subsequent proteasomal degradation of target proteins (PubMed:21980433, PubMed:33268465, PubMed:38418882, P

PDB

2ECL , 7ONI

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF12678	zf-rbx1	48 → 103	RING-H2 zinc finger domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in heart, liver, skeletal muscle and pancreas. At very low levels expressed in brain, placenta and lung. {ECO:0000269|PubMed:10512750}.

Sequence

MADVEDGEETCALASHSGSSGSKSGGDKMFSLKKWNAVAMWSWDVECDTCAICRVQVMDA
CLRCQAENKQEDCVVVWGECNHSFHNCCMSLWVKQNNRCPLCQQDWVVQRIGK

Sequence length

113

Interactions

View interactions

	KEGG		Reactome
	Ubiquitin mediated proteolysis Human immunodeficiency virus 1 infection		Neddylation Antigen processing: Ubiquitination & Proteasome degradation

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Colorectal Cancer	Colorectal Cancer	In summary, our data strongly demonstrated that upregulation of GRB7 conferred MEKi resistance in CRC cells with KRAS mutations by mediating RTK signaling through the recruitment of PLK1.		GWAS, CBGDA

Show/Hide Text Mining Associations (16)

Disease Name	Relationship Type	References
Associations from Text Mining
Adenocarcinoma	Associate	24299561
Carcinogenesis	Associate	28252001, 36644576
Carcinoma Non Small Cell Lung	Associate	24299561
Coronary Artery Disease	Associate	36743388
Endometrial Neoplasms	Associate	34082605
Fibrosis	Associate	22841784, 28338112, 28860020
Glioblastoma	Associate	31674730
Hepatitis C	Associate	22841784
Hepatitis C Chronic	Associate	28860020
Liver Cirrhosis	Associate	28338112, 28860020
Lung Neoplasms	Associate	24299561
Neoplasms	Associate	28252001, 36059474, 36644576
Pancreatic Neoplasms	Stimulate	36644576
Polycystic Ovary Syndrome	Associate	34477128
Prostatic Neoplasms	Associate	28252001, 34897998
Prostatic Neoplasms Castration Resistant	Associate	28252001

RNF7 (ring finger protein 7)