RPH3AL (rabphilin 3A like (without C2 domains))
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9501 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Rabphilin 3A like (without C2 domains) |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RPH3AL |
Synonyms (NCBI Gene)
Gene synonyms aliases
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NOC2 |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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NOC2 |
Chromosome
Chromosome number
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17 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17p13.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene plays a direct regulatory role in calcium-ion-dependent exocytosis in both endocrine and exocrine cells and plays a key role in insulin secretion by pancreatic cells. This gene is likely a tumor suppressor. Alternative spl |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9UNE2 | ||||||||||
Protein name | Rab effector Noc2 (No C2 domains protein) (Rabphilin-3A-like protein) | ||||||||||
Protein function | Rab GTPase effector involved in the late steps of regulated exocytosis, both in endocrine and exocrine cells (By similarity). Acts as a potential RAB3B effector protein in epithelial cells. | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Moderate to high levels of expression in thyroid, ovary, stomach, heart, pancreas, skeletal muscle, kidney and liver. Also detected in epithelial cells. {ECO:0000269|PubMed:10395805, ECO:0000269|PubMed:15003533}. | ||||||||||
Sequence |
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Sequence length | 315 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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