SLC4A7 (solute carrier family 4 member 7)
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9497 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Solute carrier family 4 member 7 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SLC4A7 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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NBC2, NBC3, NBCN1, SBC2, SLC4A6 |
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Chromosome
Chromosome number
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3 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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3p24.1 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This locus encodes a sodium bicarbonate cotransporter. The encoded transmembrane protein appears to transport sodium and bicarbonate ions in a 1:1 ratio, and is thus considered an electroneutral cotransporter. The encoded protein likely plays a critical r |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q9Y6M7 | |||||||||||||||
| Protein name | Sodium bicarbonate cotransporter 3 (Electroneutral Na/HCO(3) cotransporter) (Sodium bicarbonate cotransporter 2) (Sodium bicarbonate cotransporter 2b) (Bicarbonate transporter) (Solute carrier family 4 member 7) | |||||||||||||||
| Protein function | Electroneutral sodium- and bicarbonate-dependent cotransporter with a Na(+):HCO3(-) 1:1 stoichiometry (PubMed:10347222, PubMed:12403779, PubMed:14578046, PubMed:14736710). Mediates the sodium-dependent bicarbonate transport important for pH reco | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Highly expressed in testis and spleen. Also expressed in retina, colon, small intestine, ovary, thymus, prostate, muscle, heart and kidney. {ECO:0000269|PubMed:9610397}.; TISSUE SPECIFICITY: [Isoform 1]: Expressed in skeletal muscle an | |||||||||||||||
| Sequence | ||||||||||||||||
| Sequence length | 1214 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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