AKAP5 (A-kinase anchoring protein 5)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9495 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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A-kinase anchoring protein 5 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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AKAP5 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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AKAP75, AKAP79, H21 |
Chromosome
Chromosome number
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14 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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14q23.3 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P24588 | ||||||||||
Protein name | A-kinase anchor protein 5 (AKAP-5) (A-kinase anchor protein 79 kDa) (AKAP 79) (H21) (cAMP-dependent protein kinase regulatory subunit II high affinity-binding protein) | ||||||||||
Protein function | Multivalent scaffold protein that anchors the cAMP-dependent protein kinase/PKA to cytoskeletal and/or organelle-associated proteins, targeting the signal carried by cAMP to specific intracellular effectors (PubMed:1512224). Association with the | ||||||||||
PDB | 2H9R , 3LL8 , 5NIN | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Predominantly in the cerebral cortex and the postsynaptic densities of the forebrain, and to a lesser extent in adrenal medulla, lung and anterior pituitary. | ||||||||||
Sequence |
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Sequence length | 427 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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