Gene Gene information from NCBI Gene database.
Entrez ID 93611
Gene name F-box protein 44
Gene symbol FBXO44
Synonyms (NCBI Gene)
FBG3FBX30FBX6AFbx44Fbxo6a
Chromosome 1
Chromosome location 1p36.22
Summary This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box
miRNA miRNA information provided by mirtarbase database.
365
miRTarBase ID miRNA Experiments Reference
MIRT043340 hsa-miR-331-3p CLASH 23622248
MIRT658207 hsa-miR-1306-5p HITS-CLIP 23824327
MIRT658206 hsa-miR-129-1-3p HITS-CLIP 23824327
MIRT658205 hsa-miR-129-2-3p HITS-CLIP 23824327
MIRT658204 hsa-miR-6765-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 18203720, 19159283, 25416956, 27705803, 28514442, 32296183, 33961781
GO:0005737 Component Cytoplasm IBA
GO:0005737 Component Cytoplasm IEA
GO:0005829 Component Cytosol TAS
GO:0006516 Process Glycoprotein catabolic process IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
609111 24847 ENSG00000132879
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9H4M3
Protein name F-box only protein 44 (F-box protein FBX30) (F-box/G-domain protein 3)
Protein function Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
PDB 3WSO , 5B4N
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF12937 F-box-like 6 53 F-box-like Domain
PF04300 FBA 72 250 F-box associated region Family
Tissue specificity TISSUE SPECIFICITY: Abundantly expressed in brain and kidney. Expressed at lower levels in heart, spleen and liver. {ECO:0000269|PubMed:12383498}.
Sequence
Sequence length 255
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neddylation
Antigen processing: Ubiquitination & Proteasome degradation