Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
93611
Gene name Gene Name - the full gene name approved by the HGNC.
F-box protein 44
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
FBXO44
Synonyms (NCBI Gene) Gene synonyms aliases
FBG3, FBX30, FBX6A, Fbx44, Fbxo6a
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p36.22
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT043340 hsa-miR-331-3p CLASH 23622248
MIRT658207 hsa-miR-1306-5p HITS-CLIP 23824327
MIRT658206 hsa-miR-129-1-3p HITS-CLIP 23824327
MIRT658205 hsa-miR-129-2-3p HITS-CLIP 23824327
MIRT658204 hsa-miR-6765-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000209 Process Protein polyubiquitination TAS
GO:0005515 Function Protein binding IPI 18203720, 19159283, 25416956, 27705803
GO:0005737 Component Cytoplasm IBA 21873635
GO:0005829 Component Cytosol TAS
GO:0006516 Process Glycoprotein catabolic process IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
609111 24847 ENSG00000132879
Protein
UniProt ID Q9H4M3
Protein name F-box only protein 44 (F-box protein FBX30) (F-box/G-domain protein 3)
Protein function Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex.
PDB 3WSO , 5B4N
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF12937 F-box-like 6 53 F-box-like Domain
PF04300 FBA 72 250 F-box associated region Family
Tissue specificity TISSUE SPECIFICITY: Abundantly expressed in brain and kidney. Expressed at lower levels in heart, spleen and liver. {ECO:0000269|PubMed:12383498}.
Sequence
Sequence length 255
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neddylation
Antigen processing: Ubiquitination & Proteasome degradation
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Prostate cancer Malignant neoplasm of prostate rs121909139, rs121909140, rs121909141, rs121909142, rs121909143, rs606231169, rs606231170, rs137852584, rs137852578, rs137852580, rs137852581, rs137852582 17199135
Associations from Text Mining
Disease Name Relationship Type References
Adenocarcinoma Associate 36774361
Breast Neoplasms Associate 23086937
Neoplasm Metastasis Associate 36774361
Neoplasms Associate 33357448, 36774361