COPS2 (COP9 signalosome subunit 2)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9318 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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COP9 signalosome subunit 2 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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COPS2 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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ALIEN, CSN2, SGN2, TRIP15 |
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Chromosome
Chromosome number
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15 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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15q21.1 |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | P61201 | ||||||||||
| Protein name | COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15) | ||||||||||
| Protein function | Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of | ||||||||||
| PDB | 4D10 , 4D18 , 4WSN , 6A73 , 6R6H , 6R7F , 6R7H , 6R7I , 6R7N , 8H38 , 8H3A , 8H3F | ||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 443 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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