COPS2 (COP9 signalosome subunit 2)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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9318 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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COP9 signalosome subunit 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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COPS2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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ALIEN, CSN2, SGN2, TRIP15 |
Chromosome
Chromosome number
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15 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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15q21.1 |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | P61201 | ||||||||||
Protein name | COP9 signalosome complex subunit 2 (SGN2) (Signalosome subunit 2) (Alien homolog) (JAB1-containing signalosome subunit 2) (Thyroid receptor-interacting protein 15) (TR-interacting protein 15) (TRIP-15) | ||||||||||
Protein function | Essential component of the COP9 signalosome complex (CSN), a complex involved in various cellular and developmental processes. The CSN complex is an essential regulator of the ubiquitin (Ubl) conjugation pathway by mediating the deneddylation of | ||||||||||
PDB | 4D10 , 4D18 , 4WSN , 6A73 , 6R6H , 6R7F , 6R7H , 6R7I , 6R7N , 8H38 , 8H3A , 8H3F | ||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 443 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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