PKDCC (protein kinase domain containing, cytoplasmic)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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91461 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Protein kinase domain containing, cytoplasmic |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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PKDCC |
Synonyms (NCBI Gene)
Gene synonyms aliases
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RLSDF, SGK493, Vlk |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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RLSDF |
Chromosome
Chromosome number
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2 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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2p21 |
SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q504Y2 | ||||||||||
Protein name | Extracellular tyrosine-protein kinase PKDCC (EC 2.7.10.2) (Protein kinase domain-containing protein, cytoplasmic) (Protein kinase-like protein SgK493) (Sugen kinase 493) (Vertebrate lonesome kinase) | ||||||||||
Protein function | Secreted tyrosine-protein kinase that mediates phosphorylation of extracellular proteins and endogenous proteins in the secretory pathway, which is essential for patterning at organogenesis stages. Mediates phosphorylation of MMP1, MMP13, MMP14, | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Highly expressed in platelets. {ECO:0000269|PubMed:25171405}. | ||||||||||
Sequence |
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Sequence length | 493 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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