Gene Gene information from NCBI Gene database.
Entrez ID 9114
Gene name ATPase H+ transporting V0 subunit d1
Gene symbol ATP6V0D1
Synonyms (NCBI Gene)
ATP6DATP6DVP39VATXVMA6VPATPD
Chromosome 16
Chromosome location 16q22.1
Summary This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sort
miRNA miRNA information provided by mirtarbase database.
362
miRTarBase ID miRNA Experiments Reference
MIRT028941 hsa-miR-26b-5p Microarray 19088304
MIRT042487 hsa-miR-423-3p CLASH 23622248
MIRT504690 hsa-miR-8485 HITS-CLIP 23824327
MIRT504689 hsa-miR-130a-3p HITS-CLIP 23824327
MIRT504688 hsa-miR-130b-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
44
GO ID Ontology Definition Evidence Reference
GO:0000220 Component Vacuolar proton-transporting V-type ATPase, V0 domain ISS
GO:0005515 Function Protein binding IPI 16713569, 18752060, 20093472, 29644770, 30374053, 32296183, 32814053
GO:0005764 Component Lysosome IEA
GO:0005765 Component Lysosomal membrane HDA 17897319
GO:0005765 Component Lysosomal membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
607028 13724 ENSG00000159720
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
P61421
Protein name V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1)
Protein function Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:28296633, PubMed:30374053, PubMed
PDB 6WLW , 6WM2 , 6WM3 , 6WM4 , 7U4T , 7UNF
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01992 vATP-synt_AC39 16 347 ATP synthase (C/AC39) subunit Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:12384298, ECO:0000269|PubMed:8250920}.
Sequence
Sequence length 351
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  Reactome
  Oxidative phosphorylation
Metabolic pathways
Lysosome
Phagosome
Synaptic vesicle cycle
Collecting duct acid secretion
Vibrio cholerae infection
Epithelial cell signaling in Helicobacter pylori infection
Tuberculosis
Human papillomavirus infection
Viral carcinogenesis
Rheumatoid arthritis
  ROS and RNS production in phagocytes
XBP1(S) activates chaperone genes
Insulin receptor recycling
Transferrin endocytosis and recycling
Amino acids regulate mTORC1
Ion channel transport