Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
9114
Gene name Gene Name - the full gene name approved by the HGNC.
ATPase H+ transporting V0 subunit d1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
ATP6V0D1
Synonyms (NCBI Gene) Gene synonyms aliases
ATP6D, ATP6DV, P39, VATX, VMA6, VPATPD
Chromosome Chromosome number
16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
16q22.1
Summary Summary of gene provided in NCBI Entrez Gene.
This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sort
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT028941 hsa-miR-26b-5p Microarray 19088304
MIRT042487 hsa-miR-423-3p CLASH 23622248
MIRT504690 hsa-miR-8485 HITS-CLIP 23824327
MIRT504689 hsa-miR-130a-3p HITS-CLIP 23824327
MIRT504688 hsa-miR-130b-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 16713569, 18752060, 20093472, 29644770, 30374053, 32296183, 32814053
GO:0005765 Component Lysosomal membrane HDA 17897319
GO:0005765 Component Lysosomal membrane IBA 21873635
GO:0005769 Component Early endosome IBA 21873635
GO:0005813 Component Centrosome IDA 21844891
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
607028 13724 ENSG00000159720
Protein
UniProt ID P61421
Protein name V-type proton ATPase subunit d 1 (V-ATPase subunit d 1) (32 kDa accessory protein) (V-ATPase 40 kDa accessory protein) (V-ATPase AC39 subunit) (p39) (Vacuolar proton pump subunit d 1)
Protein function Subunit of the V0 complex of vacuolar(H+)-ATPase (V-ATPase), a multisubunit enzyme composed of a peripheral complex (V1) that hydrolyzes ATP and a membrane integral complex (V0) that translocates protons (PubMed:28296633, PubMed:30374053, PubMed
PDB 6WLW , 6WM2 , 6WM3 , 6WM4 , 7U4T , 7UNF
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF01992 vATP-synt_AC39 16 347 ATP synthase (C/AC39) subunit Family
Tissue specificity TISSUE SPECIFICITY: Ubiquitous. {ECO:0000269|PubMed:12384298, ECO:0000269|PubMed:8250920}.
Sequence
Sequence length 351
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Oxidative phosphorylation
Metabolic pathways
Lysosome
Phagosome
Synaptic vesicle cycle
Collecting duct acid secretion
Vibrio cholerae infection
Epithelial cell signaling in Helicobacter pylori infection
Tuberculosis
Human papillomavirus infection
Viral carcinogenesis
Rheumatoid arthritis
  ROS and RNS production in phagocytes
XBP1(S) activates chaperone genes
Insulin receptor recycling
Transferrin endocytosis and recycling
Amino acids regulate mTORC1
Ion channel transport
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Age-related macular degeneration Age related macular degeneration rs199474657, rs61750120, rs1800728, rs62654397, rs61749423, rs61751412, rs61749439, rs61751398, rs61752417, rs62645946, rs1801269, rs62646860, rs61750142, rs61750145, rs61750152
View all (20 more)
29346644
Associations from Text Mining
Disease Name Relationship Type References
Alzheimer Disease Associate 32812023