Gene Gene information from NCBI Gene database.
Entrez ID 8895
Gene name Copine 3
Gene symbol CPNE3
Synonyms (NCBI Gene)
CPN3PRO1071
Chromosome 8
Chromosome location 8q21.3
Summary Calcium-dependent membrane-binding proteins may regulate molecular events at the interface of the cell membrane and cytoplasm. This gene encodes a protein which contains two type II C2 domains in the amino-terminus and an A domain-like sequence in the car
miRNA miRNA information provided by mirtarbase database.
639
miRTarBase ID miRNA Experiments Reference
MIRT002575 hsa-miR-124-3p Microarray 15685193
MIRT007128 hsa-miR-133b Luciferase reporter assay 23451058
MIRT002575 hsa-miR-124-3p Microarray;Other 15685193
MIRT052920 hsa-miR-451a Luciferase reporter assayqRT-PCRWestern blot 24574214
MIRT052920 hsa-miR-451a Luciferase reporter assayqRT-PCRWestern blot 24574214
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
38
GO ID Ontology Definition Evidence Reference
GO:0003723 Function RNA binding HDA 22658674
GO:0004674 Function Protein serine/threonine kinase activity IDA 11041869
GO:0005515 Function Protein binding IPI 20010870, 21044950
GO:0005544 Function Calcium-dependent phospholipid binding IBA
GO:0005544 Function Calcium-dependent phospholipid binding IDA 9430674, 20010870
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
604207 2316 ENSG00000085719
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
O75131
Protein name Copine-3 (Copine III)
Protein function Calcium-dependent phospholipid-binding protein that plays a role in ERBB2-mediated tumor cell migration in response to growth factor heregulin stimulation (PubMed:20010870).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00168 C2 8 116 C2 domain Domain
PF00168 C2 138 249 C2 domain Domain
PF07002 Copine 310 527 Copine Family
Tissue specificity TISSUE SPECIFICITY: Expressed in breast and weakly in prostate and ovarian tissues (PubMed:20010870). Expressed in neutrophils (at protein level) (PubMed:12949241). Widely expressed (PubMed:11041869). Expressed in the brain. Expressed in neutrophil precur
Sequence
Sequence length 537
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Glycerophospholipid biosynthesis
Neutrophil degranulation