IER3 (immediate early response 3)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 8870 |
| Gene name | Immediate early response 3 |
| Gene symbol | IER3 |
| Synonyms (NCBI Gene) |
DIF-2DIF2GLY96IEX-1IEX-1LIEX1PRG1
|
| Chromosome | 6 |
| Chromosome location | 6p21.33 |
| Summary | This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not g |
|
miRNA
miRNA information provided by mirtarbase database.
451
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Transcription factors
Transcription factors information provided by TRRUST V2 database.
6
|
|||||||||||||||||||
|
|||||||||||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
26
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
P46695 | |
| Protein name | Radiation-inducible immediate-early gene IEX-1 (Differentiation-dependent gene 2 protein) (Protein DIF-2) (Immediate early protein GLY96) (Immediate early response 3 protein) (PACAP-responsive gene 1 protein) (Protein PRG1) | |
| Protein function | May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Also acts as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may | |
| Family and domains | ||
| Sequence |
|
|
| Sequence length | 156 | |
| Interactions | View interactions | |
|
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
|
|||||||
|
|||||||