IER3 (immediate early response 3)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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8870 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Immediate early response 3 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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IER3 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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DIF-2, DIF2, GLY96, IEX-1, IEX-1L, IEX1, PRG1 |
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Chromosome
Chromosome number
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6 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6p21.33 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene functions in the protection of cells from Fas- or tumor necrosis factor type alpha-induced apoptosis. Partially degraded and unspliced transcripts are found after virus infection in vitro, but these transcripts are not found in vivo and do not g |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||
| UniProt ID | P46695 | |
| Protein name | Radiation-inducible immediate-early gene IEX-1 (Differentiation-dependent gene 2 protein) (Protein DIF-2) (Immediate early protein GLY96) (Immediate early response 3 protein) (PACAP-responsive gene 1 protein) (Protein PRG1) | |
| Protein function | May play a role in the ERK signaling pathway by inhibiting the dephosphorylation of ERK by phosphatase PP2A-PPP2R5C holoenzyme. Also acts as an ERK downstream effector mediating survival. As a member of the NUPR1/RELB/IER3 survival pathway, may | |
| Family and domains | ||
| Sequence |
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| Sequence length | 156 | |
| Interactions | View interactions | |
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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