Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene SNPs miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	87178
Gene name	Polyribonucleotide nucleotidyltransferase 1
Gene symbol	PNPT1
Synonyms (NCBI Gene)	COXPD13DFNB70OLD35PNPASESCA25old-35
Chromosome	2
Chromosome location	2p16.1
Summary	The protein encoded by this gene belongs to the evolutionary conserved polynucleotide phosphorylase family comprised of phosphate dependent 3`-to-5` exoribonucleases implicated in RNA processing and degradation. This enzyme is predominantly localized in t

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SNP ID	Visualize variation	Clinical significance	Consequence
rs34928857	C>G	Uncertain-significance, conflicting-interpretations-of-pathogenicity	Coding sequence variant, missense variant, non coding transcript variant
rs143712760	C>A	Uncertain-significance, likely-pathogenic	Non coding transcript variant, coding sequence variant, missense variant
rs146571352	C>T	Likely-pathogenic, not-provided, uncertain-significance	Missense variant, coding sequence variant, non coding transcript variant
rs151166046	G>A	Conflicting-interpretations-of-pathogenicity	Non coding transcript variant, missense variant, coding sequence variant
rs200088200	G>C	Likely-pathogenic	Coding sequence variant, non coding transcript variant, missense variant
rs374698153	G>C	Likely-pathogenic, uncertain-significance	Non coding transcript variant, coding sequence variant, missense variant
rs397514598	T>C	Pathogenic	Missense variant, coding sequence variant, non coding transcript variant
rs397514599	T>C	Pathogenic	Missense variant, coding sequence variant, non coding transcript variant
rs746356243	C>G,T	Pathogenic	Missense variant, non coding transcript variant, coding sequence variant
rs752550279	C>A,G	Pathogenic	Genic downstream transcript variant, coding sequence variant, missense variant
rs767310806	T>C,G	Likely-pathogenic	Non coding transcript variant, coding sequence variant, missense variant
rs772153760	C>T	Likely-pathogenic	Non coding transcript variant, coding sequence variant, missense variant
rs774425075	C>T	Likely-pathogenic	Missense variant, non coding transcript variant, coding sequence variant
rs778100619	G>A,C,T	Pathogenic	Missense variant, non coding transcript variant, coding sequence variant, stop gained
rs863225449	C>T	Pathogenic	Splice acceptor variant
rs879255657	C>G	Pathogenic	Coding sequence variant, non coding transcript variant, missense variant
rs1064793593	GT>-	Pathogenic	Coding sequence variant, frameshift variant, non coding transcript variant
rs1365308037	C>A,T	Likely-pathogenic	Missense variant, coding sequence variant, non coding transcript variant
rs1553493871	A>-	Likely-pathogenic	Non coding transcript variant, frameshift variant, coding sequence variant
rs1559094461	C>G	Pathogenic	Non coding transcript variant, coding sequence variant, missense variant
rs1559114055	A>G	Pathogenic	Coding sequence variant, intron variant, 5 prime UTR variant, non coding transcript variant, missense variant
rs1572834021	C>-	Likely-pathogenic	Coding sequence variant, non coding transcript variant, frameshift variant

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miRTarBase ID	miRNA	Experiments	Reference
MIRT020848	hsa-miR-155-5p	Proteomics	18668040
MIRT706636	hsa-miR-6838-3p	HITS-CLIP	21572407
MIRT706635	hsa-miR-4781-3p	HITS-CLIP	21572407
MIRT706634	hsa-miR-370-3p	HITS-CLIP	21572407
MIRT706633	hsa-miR-6893-3p	HITS-CLIP	21572407
MIRT706632	hsa-miR-31-3p	HITS-CLIP	21572407
MIRT706631	hsa-miR-3135b	HITS-CLIP	21572407
MIRT706629	hsa-miR-3652	HITS-CLIP	21572407
MIRT706630	hsa-miR-4430	HITS-CLIP	21572407
MIRT706628	hsa-miR-6501-5p	HITS-CLIP	21572407
MIRT706627	hsa-miR-4423-5p	HITS-CLIP	21572407
MIRT706626	hsa-miR-744-3p	HITS-CLIP	21572407
MIRT625290	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT625289	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT625288	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT625287	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT625286	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT625285	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT625284	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT625283	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT625282	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT625281	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT625280	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT625279	hsa-miR-4284	HITS-CLIP	23824327
MIRT625278	hsa-miR-7977	HITS-CLIP	23824327
MIRT654948	hsa-miR-652-3p	HITS-CLIP	23824327
MIRT625290	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT654947	hsa-miR-3155a	HITS-CLIP	23824327
MIRT654946	hsa-miR-3155b	HITS-CLIP	23824327
MIRT654945	hsa-miR-484	HITS-CLIP	23824327
MIRT625289	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT625288	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT625287	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT625286	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT625285	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT625284	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT625283	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT625282	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT625281	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT625280	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT636935	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT625279	hsa-miR-4284	HITS-CLIP	23824327
MIRT625278	hsa-miR-7977	HITS-CLIP	23824327
MIRT625290	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT625285	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT625284	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT625283	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT625282	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT625281	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT625280	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT636935	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT625279	hsa-miR-4284	HITS-CLIP	23824327
MIRT625278	hsa-miR-7977	HITS-CLIP	23824327
MIRT625290	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT625289	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT625288	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT625287	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT625286	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT625285	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT625284	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT625283	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT625282	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT625281	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT625280	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT625279	hsa-miR-4284	HITS-CLIP	23824327
MIRT625278	hsa-miR-7977	HITS-CLIP	23824327
MIRT625290	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT625289	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT625288	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT625287	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT625286	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT625285	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT625284	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT625283	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT625282	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT625281	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT625280	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT625279	hsa-miR-4284	HITS-CLIP	23824327
MIRT625278	hsa-miR-7977	HITS-CLIP	23824327
MIRT625290	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT625289	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT625288	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT625287	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT625286	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT625285	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT625284	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT625283	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT625282	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT625281	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT625280	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT625279	hsa-miR-4284	HITS-CLIP	23824327
MIRT625278	hsa-miR-7977	HITS-CLIP	23824327
MIRT706636	hsa-miR-6838-3p	HITS-CLIP	21572407
MIRT706635	hsa-miR-4781-3p	HITS-CLIP	21572407
MIRT706634	hsa-miR-370-3p	HITS-CLIP	21572407
MIRT706633	hsa-miR-6893-3p	HITS-CLIP	21572407
MIRT706632	hsa-miR-31-3p	HITS-CLIP	21572407
MIRT706631	hsa-miR-3135b	HITS-CLIP	21572407
MIRT706629	hsa-miR-3652	HITS-CLIP	21572407
MIRT706630	hsa-miR-4430	HITS-CLIP	21572407
MIRT706628	hsa-miR-6501-5p	HITS-CLIP	21572407
MIRT706627	hsa-miR-4423-5p	HITS-CLIP	21572407
MIRT706626	hsa-miR-744-3p	HITS-CLIP	21572407
MIRT625290	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT625289	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT625288	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT625287	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT625286	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT625285	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT625284	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT625283	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT625282	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT625281	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT625280	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT625279	hsa-miR-4284	HITS-CLIP	23824327
MIRT625278	hsa-miR-7977	HITS-CLIP	23824327
MIRT654948	hsa-miR-652-3p	HITS-CLIP	23824327
MIRT625290	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT654947	hsa-miR-3155a	HITS-CLIP	23824327
MIRT654946	hsa-miR-3155b	HITS-CLIP	23824327
MIRT654945	hsa-miR-484	HITS-CLIP	23824327
MIRT625289	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT625288	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT625287	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT625286	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT625285	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT625284	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT625283	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT625282	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT625281	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT625280	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT636935	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT625279	hsa-miR-4284	HITS-CLIP	23824327
MIRT625278	hsa-miR-7977	HITS-CLIP	23824327
MIRT625290	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT625285	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT625284	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT625283	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT625282	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT625281	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT625280	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT636935	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT625279	hsa-miR-4284	HITS-CLIP	23824327
MIRT625278	hsa-miR-7977	HITS-CLIP	23824327
MIRT625290	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT625289	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT625288	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT625287	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT625286	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT625285	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT625284	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT625283	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT625282	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT625281	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT625280	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT625279	hsa-miR-4284	HITS-CLIP	23824327
MIRT625278	hsa-miR-7977	HITS-CLIP	23824327
MIRT625290	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT625289	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT625288	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT625287	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT625286	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT625285	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT625284	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT625283	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT625282	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT625281	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT625280	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT625279	hsa-miR-4284	HITS-CLIP	23824327
MIRT625278	hsa-miR-7977	HITS-CLIP	23824327
MIRT625290	hsa-miR-6890-3p	HITS-CLIP	23824327
MIRT625289	hsa-miR-6840-3p	HITS-CLIP	23824327
MIRT625288	hsa-miR-1915-3p	HITS-CLIP	23824327
MIRT625287	hsa-miR-6764-5p	HITS-CLIP	23824327
MIRT625286	hsa-miR-4726-3p	HITS-CLIP	23824327
MIRT625285	hsa-miR-6741-3p	HITS-CLIP	23824327
MIRT625284	hsa-miR-1304-3p	HITS-CLIP	23824327
MIRT625283	hsa-miR-136-5p	HITS-CLIP	23824327
MIRT625282	hsa-miR-1307-3p	HITS-CLIP	23824327
MIRT625281	hsa-miR-4638-5p	HITS-CLIP	23824327
MIRT625280	hsa-miR-4772-3p	HITS-CLIP	23824327
MIRT625279	hsa-miR-4284	HITS-CLIP	23824327
MIRT625278	hsa-miR-7977	HITS-CLIP	23824327
MIRT1245788	hsa-miR-101	CLIP-seq
MIRT1245789	hsa-miR-1183	CLIP-seq
MIRT1245790	hsa-miR-1200	CLIP-seq
MIRT1245791	hsa-miR-122	CLIP-seq
MIRT1245792	hsa-miR-125a-3p	CLIP-seq
MIRT1245793	hsa-miR-1273f	CLIP-seq
MIRT1245794	hsa-miR-1299	CLIP-seq
MIRT1245795	hsa-miR-130a	CLIP-seq
MIRT1245796	hsa-miR-130b	CLIP-seq
MIRT1245797	hsa-miR-1343	CLIP-seq
MIRT1245798	hsa-miR-144	CLIP-seq
MIRT1245799	hsa-miR-1915	CLIP-seq
MIRT1245800	hsa-miR-197	CLIP-seq
MIRT1245801	hsa-miR-1976	CLIP-seq
MIRT1245802	hsa-miR-205	CLIP-seq
MIRT1245803	hsa-miR-2054	CLIP-seq
MIRT1245804	hsa-miR-299-5p	CLIP-seq
MIRT1245805	hsa-miR-300	CLIP-seq
MIRT1245806	hsa-miR-301a	CLIP-seq
MIRT1245807	hsa-miR-301b	CLIP-seq
MIRT1245808	hsa-miR-3147	CLIP-seq
MIRT1245809	hsa-miR-3149	CLIP-seq
MIRT1245810	hsa-miR-3170	CLIP-seq
MIRT1245811	hsa-miR-3187-3p	CLIP-seq
MIRT1245812	hsa-miR-3194-3p	CLIP-seq
MIRT1245813	hsa-miR-3199	CLIP-seq
MIRT1245814	hsa-miR-331-5p	CLIP-seq
MIRT1245815	hsa-miR-335	CLIP-seq
MIRT1245816	hsa-miR-3616-5p	CLIP-seq
MIRT1245817	hsa-miR-3622a-5p	CLIP-seq
MIRT1245818	hsa-miR-3647-5p	CLIP-seq
MIRT1245819	hsa-miR-3662	CLIP-seq
MIRT1245820	hsa-miR-3663-5p	CLIP-seq
MIRT1245821	hsa-miR-3666	CLIP-seq
MIRT1245822	hsa-miR-370	CLIP-seq
MIRT1245823	hsa-miR-381	CLIP-seq
MIRT1245824	hsa-miR-382	CLIP-seq
MIRT1245825	hsa-miR-3934	CLIP-seq
MIRT1245826	hsa-miR-3940-5p	CLIP-seq
MIRT1245827	hsa-miR-410	CLIP-seq
MIRT1245828	hsa-miR-411	CLIP-seq
MIRT1245829	hsa-miR-4269	CLIP-seq
MIRT1245830	hsa-miR-4279	CLIP-seq
MIRT1245831	hsa-miR-4294	CLIP-seq
MIRT1245832	hsa-miR-4295	CLIP-seq
MIRT1245833	hsa-miR-431	CLIP-seq
MIRT1245834	hsa-miR-4324	CLIP-seq
MIRT1245835	hsa-miR-433	CLIP-seq
MIRT1245836	hsa-miR-4425	CLIP-seq
MIRT1245837	hsa-miR-4426	CLIP-seq
MIRT1245838	hsa-miR-4435	CLIP-seq
MIRT1245839	hsa-miR-4438	CLIP-seq
MIRT1245840	hsa-miR-4507	CLIP-seq
MIRT1245841	hsa-miR-454	CLIP-seq
MIRT1245842	hsa-miR-4647	CLIP-seq
MIRT1245843	hsa-miR-4652-3p	CLIP-seq
MIRT1245844	hsa-miR-4662a-5p	CLIP-seq
MIRT1245845	hsa-miR-4662b	CLIP-seq
MIRT1245846	hsa-miR-4666-3p	CLIP-seq
MIRT1245847	hsa-miR-4676-5p	CLIP-seq
MIRT1245848	hsa-miR-4701-5p	CLIP-seq
MIRT1245849	hsa-miR-4715-3p	CLIP-seq
MIRT1245850	hsa-miR-4716-5p	CLIP-seq
MIRT1245851	hsa-miR-4722-3p	CLIP-seq
MIRT1245852	hsa-miR-4724-3p	CLIP-seq
MIRT1245853	hsa-miR-4735-5p	CLIP-seq
MIRT1245854	hsa-miR-4755-3p	CLIP-seq
MIRT1245855	hsa-miR-4763-5p	CLIP-seq
MIRT1245856	hsa-miR-4775	CLIP-seq
MIRT1245857	hsa-miR-4782-5p	CLIP-seq
MIRT1245858	hsa-miR-4795-5p	CLIP-seq
MIRT1245859	hsa-miR-489	CLIP-seq
MIRT1245860	hsa-miR-493	CLIP-seq
MIRT1245861	hsa-miR-5095	CLIP-seq
MIRT1245862	hsa-miR-5096	CLIP-seq
MIRT1245863	hsa-miR-513a-3p	CLIP-seq
MIRT1245864	hsa-miR-516b	CLIP-seq
MIRT1245865	hsa-miR-520d-5p	CLIP-seq
MIRT1245866	hsa-miR-524-5p	CLIP-seq
MIRT1245867	hsa-miR-544b	CLIP-seq
MIRT1245868	hsa-miR-548ag	CLIP-seq
MIRT1245869	hsa-miR-548ai	CLIP-seq
MIRT1245870	hsa-miR-548g	CLIP-seq
MIRT1245871	hsa-miR-548s	CLIP-seq
MIRT1245872	hsa-miR-550a	CLIP-seq
MIRT1245873	hsa-miR-552	CLIP-seq
MIRT1245874	hsa-miR-561	CLIP-seq
MIRT1245875	hsa-miR-573	CLIP-seq
MIRT1245876	hsa-miR-575	CLIP-seq
MIRT1245877	hsa-miR-577	CLIP-seq
MIRT1245878	hsa-miR-588	CLIP-seq
MIRT1245879	hsa-miR-590-3p	CLIP-seq
MIRT1245880	hsa-miR-652	CLIP-seq
MIRT1245881	hsa-miR-656	CLIP-seq
MIRT1245882	hsa-miR-659	CLIP-seq
MIRT1245883	hsa-miR-668	CLIP-seq
MIRT1245884	hsa-miR-764	CLIP-seq
MIRT1245885	hsa-miR-9	CLIP-seq
MIRT1245886	hsa-miR-924	CLIP-seq
MIRT1245884	hsa-miR-764	CLIP-seq
MIRT2072659	hsa-miR-106a	CLIP-seq
MIRT2072660	hsa-miR-106b	CLIP-seq
MIRT1245790	hsa-miR-1200	CLIP-seq
MIRT2072661	hsa-miR-1234	CLIP-seq
MIRT1245792	hsa-miR-125a-3p	CLIP-seq
MIRT1245793	hsa-miR-1273f	CLIP-seq
MIRT2072662	hsa-miR-1287	CLIP-seq
MIRT2072663	hsa-miR-129-5p	CLIP-seq
MIRT2072664	hsa-miR-1307	CLIP-seq
MIRT1245797	hsa-miR-1343	CLIP-seq
MIRT2072665	hsa-miR-150	CLIP-seq
MIRT2072666	hsa-miR-17	CLIP-seq
MIRT1245799	hsa-miR-1915	CLIP-seq
MIRT1245800	hsa-miR-197	CLIP-seq
MIRT1245801	hsa-miR-1976	CLIP-seq
MIRT2072667	hsa-miR-20a	CLIP-seq
MIRT2072668	hsa-miR-20b	CLIP-seq
MIRT2072669	hsa-miR-302a	CLIP-seq
MIRT2072670	hsa-miR-302b	CLIP-seq
MIRT2072671	hsa-miR-302c	CLIP-seq
MIRT2072672	hsa-miR-302d	CLIP-seq
MIRT2072673	hsa-miR-302e	CLIP-seq
MIRT1245809	hsa-miR-3149	CLIP-seq
MIRT2072674	hsa-miR-3159	CLIP-seq
MIRT1245810	hsa-miR-3170	CLIP-seq
MIRT1245811	hsa-miR-3187-3p	CLIP-seq
MIRT1245815	hsa-miR-335	CLIP-seq
MIRT1245816	hsa-miR-3616-5p	CLIP-seq
MIRT1245818	hsa-miR-3647-5p	CLIP-seq
MIRT1245820	hsa-miR-3663-5p	CLIP-seq
MIRT2072675	hsa-miR-372	CLIP-seq
MIRT2072676	hsa-miR-373	CLIP-seq
MIRT1245825	hsa-miR-3934	CLIP-seq
MIRT1245826	hsa-miR-3940-5p	CLIP-seq
MIRT1245828	hsa-miR-411	CLIP-seq
MIRT2072677	hsa-miR-4258	CLIP-seq
MIRT1245830	hsa-miR-4279	CLIP-seq
MIRT1245834	hsa-miR-4324	CLIP-seq
MIRT2072678	hsa-miR-4325	CLIP-seq
MIRT1245838	hsa-miR-4435	CLIP-seq
MIRT1245839	hsa-miR-4438	CLIP-seq
MIRT2072679	hsa-miR-4476	CLIP-seq
MIRT1245840	hsa-miR-4507	CLIP-seq
MIRT2072680	hsa-miR-450b-5p	CLIP-seq
MIRT2072681	hsa-miR-4695-3p	CLIP-seq
MIRT1245848	hsa-miR-4701-5p	CLIP-seq
MIRT2072682	hsa-miR-4707-3p	CLIP-seq
MIRT1245849	hsa-miR-4715-3p	CLIP-seq
MIRT1245850	hsa-miR-4716-5p	CLIP-seq
MIRT1245851	hsa-miR-4722-3p	CLIP-seq
MIRT1245853	hsa-miR-4735-5p	CLIP-seq
MIRT2072683	hsa-miR-4740-3p	CLIP-seq
MIRT1245854	hsa-miR-4755-3p	CLIP-seq
MIRT1245856	hsa-miR-4775	CLIP-seq
MIRT2072684	hsa-miR-4787-3p	CLIP-seq
MIRT1245858	hsa-miR-4795-5p	CLIP-seq
MIRT2072685	hsa-miR-499-3p	CLIP-seq
MIRT2072686	hsa-miR-499a-3p	CLIP-seq
MIRT2072687	hsa-miR-507	CLIP-seq
MIRT1245861	hsa-miR-5095	CLIP-seq
MIRT1245862	hsa-miR-5096	CLIP-seq
MIRT2072688	hsa-miR-512-3p	CLIP-seq
MIRT2072689	hsa-miR-519d	CLIP-seq
MIRT2072690	hsa-miR-520a-3p	CLIP-seq
MIRT2072691	hsa-miR-520b	CLIP-seq
MIRT2072692	hsa-miR-520c-3p	CLIP-seq
MIRT2072693	hsa-miR-520d-3p	CLIP-seq
MIRT2072694	hsa-miR-520e	CLIP-seq
MIRT2072695	hsa-miR-520g	CLIP-seq
MIRT2072696	hsa-miR-520h	CLIP-seq
MIRT1245867	hsa-miR-544b	CLIP-seq
MIRT1245871	hsa-miR-548s	CLIP-seq
MIRT1245873	hsa-miR-552	CLIP-seq
MIRT2072697	hsa-miR-557	CLIP-seq
MIRT1245875	hsa-miR-573	CLIP-seq
MIRT1245878	hsa-miR-588	CLIP-seq
MIRT1245879	hsa-miR-590-3p	CLIP-seq
MIRT1245884	hsa-miR-764	CLIP-seq
MIRT2072698	hsa-miR-93	CLIP-seq
MIRT1245788	hsa-miR-101	CLIP-seq
MIRT1245790	hsa-miR-1200	CLIP-seq
MIRT1245791	hsa-miR-122	CLIP-seq
MIRT2299862	hsa-miR-1254	CLIP-seq
MIRT1245793	hsa-miR-1273f	CLIP-seq
MIRT2072663	hsa-miR-129-5p	CLIP-seq
MIRT2072664	hsa-miR-1307	CLIP-seq
MIRT1245795	hsa-miR-130a	CLIP-seq
MIRT1245796	hsa-miR-130b	CLIP-seq
MIRT1245797	hsa-miR-1343	CLIP-seq
MIRT1245798	hsa-miR-144	CLIP-seq
MIRT2072665	hsa-miR-150	CLIP-seq
MIRT1245799	hsa-miR-1915	CLIP-seq
MIRT1245800	hsa-miR-197	CLIP-seq
MIRT1245801	hsa-miR-1976	CLIP-seq
MIRT1245806	hsa-miR-301a	CLIP-seq
MIRT1245807	hsa-miR-301b	CLIP-seq
MIRT2299863	hsa-miR-3116	CLIP-seq
MIRT1245808	hsa-miR-3147	CLIP-seq
MIRT1245809	hsa-miR-3149	CLIP-seq
MIRT2299864	hsa-miR-3155	CLIP-seq
MIRT2072674	hsa-miR-3159	CLIP-seq
MIRT1245810	hsa-miR-3170	CLIP-seq
MIRT1245811	hsa-miR-3187-3p	CLIP-seq
MIRT1245812	hsa-miR-3194-3p	CLIP-seq
MIRT1245816	hsa-miR-3616-5p	CLIP-seq
MIRT1245818	hsa-miR-3647-5p	CLIP-seq
MIRT1245820	hsa-miR-3663-5p	CLIP-seq
MIRT1245821	hsa-miR-3666	CLIP-seq
MIRT1245825	hsa-miR-3934	CLIP-seq
MIRT1245826	hsa-miR-3940-5p	CLIP-seq
MIRT1245828	hsa-miR-411	CLIP-seq
MIRT2072677	hsa-miR-4258	CLIP-seq
MIRT1245830	hsa-miR-4279	CLIP-seq
MIRT1245831	hsa-miR-4294	CLIP-seq
MIRT1245832	hsa-miR-4295	CLIP-seq
MIRT1245833	hsa-miR-431	CLIP-seq
MIRT1245834	hsa-miR-4324	CLIP-seq
MIRT2072678	hsa-miR-4325	CLIP-seq
MIRT1245836	hsa-miR-4425	CLIP-seq
MIRT1245837	hsa-miR-4426	CLIP-seq
MIRT1245838	hsa-miR-4435	CLIP-seq
MIRT1245839	hsa-miR-4438	CLIP-seq
MIRT1245840	hsa-miR-4507	CLIP-seq
MIRT2299865	hsa-miR-450b-3p	CLIP-seq
MIRT1245841	hsa-miR-454	CLIP-seq
MIRT2299866	hsa-miR-4643	CLIP-seq
MIRT1245842	hsa-miR-4647	CLIP-seq
MIRT2299867	hsa-miR-466	CLIP-seq
MIRT1245845	hsa-miR-4662b	CLIP-seq
MIRT2072681	hsa-miR-4695-3p	CLIP-seq
MIRT1245848	hsa-miR-4701-5p	CLIP-seq
MIRT2072682	hsa-miR-4707-3p	CLIP-seq
MIRT1245849	hsa-miR-4715-3p	CLIP-seq
MIRT1245850	hsa-miR-4716-5p	CLIP-seq
MIRT1245851	hsa-miR-4722-3p	CLIP-seq
MIRT2299868	hsa-miR-4727-5p	CLIP-seq
MIRT1245853	hsa-miR-4735-5p	CLIP-seq
MIRT2072683	hsa-miR-4740-3p	CLIP-seq
MIRT1245854	hsa-miR-4755-3p	CLIP-seq
MIRT1245856	hsa-miR-4775	CLIP-seq
MIRT2072684	hsa-miR-4787-3p	CLIP-seq
MIRT2299869	hsa-miR-4789-3p	CLIP-seq
MIRT1245858	hsa-miR-4795-5p	CLIP-seq
MIRT2072687	hsa-miR-507	CLIP-seq
MIRT1245861	hsa-miR-5095	CLIP-seq
MIRT1245862	hsa-miR-5096	CLIP-seq
MIRT2072695	hsa-miR-520g	CLIP-seq
MIRT2072696	hsa-miR-520h	CLIP-seq
MIRT1245867	hsa-miR-544b	CLIP-seq
MIRT1245871	hsa-miR-548s	CLIP-seq
MIRT1245873	hsa-miR-552	CLIP-seq
MIRT2072697	hsa-miR-557	CLIP-seq
MIRT1245875	hsa-miR-573	CLIP-seq
MIRT1245878	hsa-miR-588	CLIP-seq
MIRT1245879	hsa-miR-590-3p	CLIP-seq
MIRT1245880	hsa-miR-652	CLIP-seq
MIRT2299870	hsa-miR-661	CLIP-seq
MIRT2299871	hsa-miR-769-3p	CLIP-seq
MIRT1245886	hsa-miR-924	CLIP-seq
MIRT1245788	hsa-miR-101	CLIP-seq
MIRT1245791	hsa-miR-122	CLIP-seq
MIRT2072664	hsa-miR-1307	CLIP-seq
MIRT1245795	hsa-miR-130a	CLIP-seq
MIRT1245796	hsa-miR-130b	CLIP-seq
MIRT1245797	hsa-miR-1343	CLIP-seq
MIRT1245798	hsa-miR-144	CLIP-seq
MIRT1245806	hsa-miR-301a	CLIP-seq
MIRT1245807	hsa-miR-301b	CLIP-seq
MIRT2392778	hsa-miR-3160-3p	CLIP-seq
MIRT2392779	hsa-miR-3182	CLIP-seq
MIRT1245816	hsa-miR-3616-5p	CLIP-seq
MIRT1245818	hsa-miR-3647-5p	CLIP-seq
MIRT1245821	hsa-miR-3666	CLIP-seq
MIRT1245826	hsa-miR-3940-5p	CLIP-seq
MIRT1245832	hsa-miR-4295	CLIP-seq
MIRT2392780	hsa-miR-4487	CLIP-seq
MIRT1245840	hsa-miR-4507	CLIP-seq
MIRT1245841	hsa-miR-454	CLIP-seq
MIRT1245858	hsa-miR-4795-5p	CLIP-seq
MIRT2392781	hsa-miR-558	CLIP-seq
MIRT1245875	hsa-miR-573	CLIP-seq
MIRT1245880	hsa-miR-652	CLIP-seq
MIRT1245790	hsa-miR-1200	CLIP-seq
MIRT1245793	hsa-miR-1273f	CLIP-seq
MIRT1245799	hsa-miR-1915	CLIP-seq
MIRT1245801	hsa-miR-1976	CLIP-seq
MIRT1245809	hsa-miR-3149	CLIP-seq
MIRT1245810	hsa-miR-3170	CLIP-seq
MIRT1245815	hsa-miR-335	CLIP-seq
MIRT1245828	hsa-miR-411	CLIP-seq
MIRT2072677	hsa-miR-4258	CLIP-seq
MIRT1245830	hsa-miR-4279	CLIP-seq
MIRT1245834	hsa-miR-4324	CLIP-seq
MIRT1245839	hsa-miR-4438	CLIP-seq
MIRT2072682	hsa-miR-4707-3p	CLIP-seq
MIRT1245849	hsa-miR-4715-3p	CLIP-seq
MIRT1245851	hsa-miR-4722-3p	CLIP-seq
MIRT1245853	hsa-miR-4735-5p	CLIP-seq
MIRT1245856	hsa-miR-4775	CLIP-seq
MIRT1245861	hsa-miR-5095	CLIP-seq
MIRT1245867	hsa-miR-544b	CLIP-seq
MIRT1245879	hsa-miR-590-3p	CLIP-seq
MIRT1245793	hsa-miR-1273f	CLIP-seq
MIRT1245799	hsa-miR-1915	CLIP-seq
MIRT1245801	hsa-miR-1976	CLIP-seq
MIRT1245809	hsa-miR-3149	CLIP-seq
MIRT1245810	hsa-miR-3170	CLIP-seq
MIRT1245815	hsa-miR-335	CLIP-seq
MIRT1245828	hsa-miR-411	CLIP-seq
MIRT2072677	hsa-miR-4258	CLIP-seq
MIRT1245830	hsa-miR-4279	CLIP-seq
MIRT2072682	hsa-miR-4707-3p	CLIP-seq
MIRT1245849	hsa-miR-4715-3p	CLIP-seq
MIRT1245851	hsa-miR-4722-3p	CLIP-seq
MIRT1245853	hsa-miR-4735-5p	CLIP-seq
MIRT1245856	hsa-miR-4775	CLIP-seq
MIRT1245879	hsa-miR-590-3p	CLIP-seq
MIRT1245789	hsa-miR-1183	CLIP-seq
MIRT1245790	hsa-miR-1200	CLIP-seq
MIRT1245791	hsa-miR-122	CLIP-seq
MIRT1245793	hsa-miR-1273f	CLIP-seq
MIRT2072663	hsa-miR-129-5p	CLIP-seq
MIRT2072664	hsa-miR-1307	CLIP-seq
MIRT1245795	hsa-miR-130a	CLIP-seq
MIRT1245796	hsa-miR-130b	CLIP-seq
MIRT1245799	hsa-miR-1915	CLIP-seq
MIRT1245800	hsa-miR-197	CLIP-seq
MIRT1245801	hsa-miR-1976	CLIP-seq
MIRT1245805	hsa-miR-300	CLIP-seq
MIRT1245806	hsa-miR-301a	CLIP-seq
MIRT1245807	hsa-miR-301b	CLIP-seq
MIRT1245809	hsa-miR-3149	CLIP-seq
MIRT1245810	hsa-miR-3170	CLIP-seq
MIRT1245811	hsa-miR-3187-3p	CLIP-seq
MIRT1245815	hsa-miR-335	CLIP-seq
MIRT1245821	hsa-miR-3666	CLIP-seq
MIRT2596573	hsa-miR-369-3p	CLIP-seq
MIRT2596574	hsa-miR-374a	CLIP-seq
MIRT2596575	hsa-miR-374b	CLIP-seq
MIRT1245823	hsa-miR-381	CLIP-seq
MIRT1245828	hsa-miR-411	CLIP-seq
MIRT2596576	hsa-miR-425	CLIP-seq
MIRT2072677	hsa-miR-4258	CLIP-seq
MIRT1245830	hsa-miR-4279	CLIP-seq
MIRT1245832	hsa-miR-4295	CLIP-seq
MIRT1245834	hsa-miR-4324	CLIP-seq
MIRT2072678	hsa-miR-4325	CLIP-seq
MIRT1245837	hsa-miR-4426	CLIP-seq
MIRT1245838	hsa-miR-4435	CLIP-seq
MIRT1245839	hsa-miR-4438	CLIP-seq
MIRT2072679	hsa-miR-4476	CLIP-seq
MIRT2072680	hsa-miR-450b-5p	CLIP-seq
MIRT1245841	hsa-miR-454	CLIP-seq
MIRT1245842	hsa-miR-4647	CLIP-seq
MIRT1245845	hsa-miR-4662b	CLIP-seq
MIRT1245846	hsa-miR-4666-3p	CLIP-seq
MIRT1245848	hsa-miR-4701-5p	CLIP-seq
MIRT2072682	hsa-miR-4707-3p	CLIP-seq
MIRT1245849	hsa-miR-4715-3p	CLIP-seq
MIRT1245850	hsa-miR-4716-5p	CLIP-seq
MIRT1245851	hsa-miR-4722-3p	CLIP-seq
MIRT1245853	hsa-miR-4735-5p	CLIP-seq
MIRT1245854	hsa-miR-4755-3p	CLIP-seq
MIRT1245855	hsa-miR-4763-5p	CLIP-seq
MIRT1245856	hsa-miR-4775	CLIP-seq
MIRT2072684	hsa-miR-4787-3p	CLIP-seq
MIRT2596577	hsa-miR-4803	CLIP-seq
MIRT2072687	hsa-miR-507	CLIP-seq
MIRT1245861	hsa-miR-5095	CLIP-seq
MIRT1245862	hsa-miR-5096	CLIP-seq
MIRT1245865	hsa-miR-520d-5p	CLIP-seq
MIRT1245866	hsa-miR-524-5p	CLIP-seq
MIRT1245867	hsa-miR-544b	CLIP-seq
MIRT1245871	hsa-miR-548s	CLIP-seq
MIRT1245872	hsa-miR-550a	CLIP-seq
MIRT2072697	hsa-miR-557	CLIP-seq
MIRT1245878	hsa-miR-588	CLIP-seq
MIRT1245879	hsa-miR-590-3p	CLIP-seq
MIRT1245880	hsa-miR-652	CLIP-seq
MIRT1245883	hsa-miR-668	CLIP-seq
MIRT1245789	hsa-miR-1183	CLIP-seq
MIRT1245790	hsa-miR-1200	CLIP-seq
MIRT1245791	hsa-miR-122	CLIP-seq
MIRT1245793	hsa-miR-1273f	CLIP-seq
MIRT2072664	hsa-miR-1307	CLIP-seq
MIRT1245795	hsa-miR-130a	CLIP-seq
MIRT1245796	hsa-miR-130b	CLIP-seq
MIRT1245799	hsa-miR-1915	CLIP-seq
MIRT1245800	hsa-miR-197	CLIP-seq
MIRT1245801	hsa-miR-1976	CLIP-seq
MIRT1245805	hsa-miR-300	CLIP-seq
MIRT1245806	hsa-miR-301a	CLIP-seq
MIRT1245807	hsa-miR-301b	CLIP-seq
MIRT1245809	hsa-miR-3149	CLIP-seq
MIRT1245810	hsa-miR-3170	CLIP-seq
MIRT1245811	hsa-miR-3187-3p	CLIP-seq
MIRT1245815	hsa-miR-335	CLIP-seq
MIRT1245821	hsa-miR-3666	CLIP-seq
MIRT1245823	hsa-miR-381	CLIP-seq
MIRT1245828	hsa-miR-411	CLIP-seq
MIRT2072677	hsa-miR-4258	CLIP-seq
MIRT1245830	hsa-miR-4279	CLIP-seq
MIRT1245832	hsa-miR-4295	CLIP-seq
MIRT1245834	hsa-miR-4324	CLIP-seq
MIRT1245837	hsa-miR-4426	CLIP-seq
MIRT1245838	hsa-miR-4435	CLIP-seq
MIRT1245839	hsa-miR-4438	CLIP-seq
MIRT2072679	hsa-miR-4476	CLIP-seq
MIRT1245841	hsa-miR-454	CLIP-seq
MIRT1245842	hsa-miR-4647	CLIP-seq
MIRT1245845	hsa-miR-4662b	CLIP-seq
MIRT1245846	hsa-miR-4666-3p	CLIP-seq
MIRT1245848	hsa-miR-4701-5p	CLIP-seq
MIRT2072682	hsa-miR-4707-3p	CLIP-seq
MIRT1245849	hsa-miR-4715-3p	CLIP-seq
MIRT1245850	hsa-miR-4716-5p	CLIP-seq
MIRT1245851	hsa-miR-4722-3p	CLIP-seq
MIRT1245853	hsa-miR-4735-5p	CLIP-seq
MIRT1245854	hsa-miR-4755-3p	CLIP-seq
MIRT1245855	hsa-miR-4763-5p	CLIP-seq
MIRT1245856	hsa-miR-4775	CLIP-seq
MIRT1245861	hsa-miR-5095	CLIP-seq
MIRT1245862	hsa-miR-5096	CLIP-seq
MIRT1245865	hsa-miR-520d-5p	CLIP-seq
MIRT1245866	hsa-miR-524-5p	CLIP-seq
MIRT1245867	hsa-miR-544b	CLIP-seq
MIRT1245871	hsa-miR-548s	CLIP-seq
MIRT1245872	hsa-miR-550a	CLIP-seq
MIRT1245878	hsa-miR-588	CLIP-seq
MIRT1245879	hsa-miR-590-3p	CLIP-seq
MIRT1245880	hsa-miR-652	CLIP-seq
MIRT1245883	hsa-miR-668	CLIP-seq

Show/Hide all (71)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000175	Function	3'-5'-RNA exonuclease activity	IBA
GO:0000175	Function	3'-5'-RNA exonuclease activity	IDA	19509288
GO:0000175	Function	3'-5'-RNA exonuclease activity	TAS
GO:0000957	Process	Mitochondrial RNA catabolic process	IDA	18501193, 29967381, 39019044
GO:0000957	Process	Mitochondrial RNA catabolic process	TAS
GO:0000958	Process	Mitochondrial mRNA catabolic process	IBA
GO:0000958	Process	Mitochondrial mRNA catabolic process	IDA	20691904
GO:0000958	Process	Mitochondrial mRNA catabolic process	IEA
GO:0000958	Process	Mitochondrial mRNA catabolic process	IMP	22661577
GO:0000962	Process	Positive regulation of mitochondrial RNA catabolic process	IDA	19509288
GO:0000964	Process	Mitochondrial RNA 5'-end processing	IMP	18083837
GO:0000965	Process	Mitochondrial RNA 3'-end processing	IBA
GO:0000965	Process	Mitochondrial RNA 3'-end processing	IMP	18083837
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	HDA	22681889
GO:0003723	Function	RNA binding	IEA
GO:0004518	Function	Nuclease activity	IEA
GO:0004527	Function	Exonuclease activity	IEA
GO:0004654	Function	Polyribonucleotide nucleotidyltransferase activity	IBA
GO:0004654	Function	Polyribonucleotide nucleotidyltransferase activity	IDA	18083836
GO:0004654	Function	Polyribonucleotide nucleotidyltransferase activity	IEA
GO:0005515	Function	Protein binding	IPI	16934922, 19509288, 28514442, 29967381, 32296183, 33961781, 39251607
GO:0005737	Component	Cytoplasm	IDA	16055741
GO:0005737	Component	Cytoplasm	IEA
GO:0005739	Component	Mitochondrion	HTP	34800366
GO:0005739	Component	Mitochondrion	IBA
GO:0005739	Component	Mitochondrion	IDA	16055741, 19864255, 20691904
GO:0005739	Component	Mitochondrion	IEA
GO:0005758	Component	Mitochondrial intermembrane space	IDA	16966381
GO:0005758	Component	Mitochondrial intermembrane space	IEA
GO:0005759	Component	Mitochondrial matrix	IDA	39019044
GO:0005759	Component	Mitochondrial matrix	IEA
GO:0005759	Component	Mitochondrial matrix	TAS
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0005829	Component	Cytosol	IBA
GO:0005829	Component	Cytosol	IDA
GO:0005840	Component	Ribosome	IEA
GO:0006396	Process	RNA processing	IEA
GO:0006397	Process	MRNA processing	IEA
GO:0006401	Process	RNA catabolic process	IDA	18083836
GO:0006402	Process	MRNA catabolic process	IDA	12721301, 16055741
GO:0006402	Process	MRNA catabolic process	IEA
GO:0007005	Process	Mitochondrion organization	IEA
GO:0007005	Process	Mitochondrion organization	ISS
GO:0008266	Function	Poly(U) RNA binding	IDA	18083836
GO:0016020	Component	Membrane	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0016779	Function	Nucleotidyltransferase activity	IEA
GO:0016787	Function	Hydrolase activity	IEA
GO:0034046	Function	Poly(G) binding	IDA	18083836
GO:0034599	Process	Cellular response to oxidative stress	IDA	18501193
GO:0035198	Function	MiRNA binding	IDA	20547861
GO:0035458	Process	Cellular response to interferon-beta	IDA	16410805
GO:0035927	Process	RNA import into mitochondrion	IDA	20691904
GO:0035928	Process	RRNA import into mitochondrion	IDA	20691904
GO:0042802	Function	Identical protein binding	IPI	19509288
GO:0043457	Process	Regulation of cellular respiration	IEA
GO:0043457	Process	Regulation of cellular respiration	ISS
GO:0045025	Component	Mitochondrial degradosome	IDA	19509288, 29967381
GO:0051260	Process	Protein homooligomerization	IDA	20691904
GO:0051591	Process	Response to cAMP	IEA
GO:0060416	Process	Response to growth hormone	IEA
GO:0061014	Process	Positive regulation of mRNA catabolic process	IEA
GO:0061014	Process	Positive regulation of mRNA catabolic process	IMP	16410805
GO:0070207	Process	Protein homotrimerization	IDA	19509288, 20691904
GO:0071042	Process	Nuclear polyadenylation-dependent mRNA catabolic process	IDA	16934922
GO:0097222	Process	Mitochondrial mRNA polyadenylation	IMP	18083837
GO:0097421	Process	Liver regeneration	IEA
GO:1905354	Component	Exoribonuclease complex	IEA
GO:2000627	Process	Positive regulation of miRNA catabolic process	IDA	20547861
GO:2000772	Process	Regulation of cellular senescence	IDA	16055741

MIM	HGNC	e!Ensembl
610316	23166	ENSG00000138035

Q8TCS8

Protein name

Polyribonucleotide nucleotidyltransferase 1, mitochondrial (EC 2.7.7.8) (3'-5' RNA exonuclease OLD35) (PNPase old-35) (Polynucleotide phosphorylase 1) (PNPase 1) (Polynucleotide phosphorylase-like protein)

Protein function

RNA-binding protein implicated in numerous RNA metabolic processes (PubMed:29967381, PubMed:39019044). Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'-to-5' direction (PubMed:29967381, PubMed:39019044).

PDB

3U1K , 5ZF6 , 9KJR , 9KJT

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF01138	RNase_PH	52 → 183		Domain
PF03725	RNase_PH_C	186 → 251		Domain
PF03726	PNPase	282 → 363	Polyribonucleotide nucleotidyltransferase, RNA binding domain	Domain
PF01138	RNase_PH	366 → 501		Domain
PF00013	KH_1	607 → 666	KH domain	Domain
PF00575	S1	675 → 750	S1 RNA binding domain	Domain

Sequence

MAACRYCCSCLRLRPLSDGPFLLPRRDRALTQLQVRALWSSAGSRAVAVDLGNRKLEISS
GKLARFADGSAVVQSGDTAVMVTAVSKTKPSPSQFMPLVVDYRQKAAAAGRIPTNYLRRE
IGTSDKEILTSRIIDRSIRPLFPAGYFYDTQVLCNLLAVDGVNEPDVLAINGASVALSLS
DIPWNGPVGAVRIGIIDGEYVVNPTRKEMSSSTLNLVVAGAPKSQIVMLEASAENILQQD
FCHAIKVGVKYTQQIIQGIQQLVKETGVTKRTPQKLFTPSPEIVKYTHKLAMERLYAVFT
DYEHDKVSRDEAVNKIRLDTEEQLKEKFPEADPYEIIESFNVVAKEVFRSIVLNEYKRCD
GRDLTSLRNVSCEVDMFKTLHGSALFQRGQTQVLCTVTFDSLESGIKSDQVITAINGIKD
KNFMLHYEFPPYATNEIGKVTGLNRRELGHGALAEKALYPVIPRDFPFTIRVTSEVLESN
GSSSMASACGGSLALMDSGVPISSAVAGVAIGLVTKTDPEKGEIEDYRLLTDILGIEDYN
GDMDFKIAGTNKGITALQADIKLPGIPIKIVMEAIQQASVAKKEILQIMNKTISKPRASR
KENGPVVETVQVPLSKRAKFVGPGGYNLKKLQAETGVTISQVDEETFSVFAPTPSAMHEA
RDFITEICKDDQEQQLEFGAVYTATITEIRDTGVMVKLYPNMTAVLLHNTQLDQRKIKHP
TALGLEVGQEIQVKYFGRDPADGRMRLSRKVLQSPATTVVRTLNDRSSIVMGEPISQSSS
NSQ

Sequence length

783

Interactions

View interactions

	KEGG
	RNA degradation

190

Show/Hide Causal Diseases (7)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Causal Diseases associated with Pathogenic or Likely Pathogenic variants in ClinVar
Autosomal recessive nonsyndromic hearing loss 70	Pathogenic; Likely pathogenic	rs1696930196, rs1478363532, rs35239216, rs991366882, rs143712760, rs397514599, rs1049082567	RCV001336838 RCV001336835 RCV002265053 RCV002283958 RCV001089488 RCV000033023 RCV001089489
Combined oxidative phosphorylation defect type 13	Likely pathogenic; Pathogenic	rs1695931094, rs2104038061, rs1329170892, rs775717775, rs143712760, rs780383722, rs863225449, rs879255657, rs778100619, rs755065532, rs397514598, rs746356243, rs1559114055, rs752550279, rs1559094461, rs1365308037, rs1049082567 View all (2 more)	RCV001332754 RCV002274863 RCV002472030 RCV002472072 RCV000680151 RCV003314052 RCV000202393 RCV000239707 RCV000239625 RCV003991950 RCV000033022 RCV000714514 RCV000714515 RCV000714516 RCV000714517 RCV000986759 RCV001089489
Global developmental delay	Likely pathogenic; Pathogenic	rs992877769	RCV002463864
Neurodevelopmental disorder	Likely pathogenic; Pathogenic	rs143712760, rs1572834021	RCV000787360 RCV000787359
Ovarian serous cystadenocarcinoma	Likely pathogenic	rs755065532	RCV005937397
PNPT1-related disorder	Pathogenic; Likely pathogenic	rs1696930196, rs572684828, rs2529522692, rs2529577004, rs1448753696, rs2529560640	RCV004531125 RCV003155418 RCV003226870 RCV003335859 RCV004542643 RCV004579635
Spinocerebellar ataxia type 25	Pathogenic; Likely pathogenic	rs2104026165, rs748445058, rs143712760, rs2529627773	RCV002265066 RCV002265067 RCV003152598 RCV004515752

Show/Hide Unknown Diseases (24)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Adrenocortical carcinoma, hereditary	Benign; Likely benign	rs745754666	RCV005868574
Cervical cancer	Likely benign	rs72807624	RCV005904252
Cholangiocarcinoma	Benign; Likely benign	rs745754666	RCV005868577
Chronic lymphocytic leukemia/small lymphocytic lymphoma	Likely benign	rs72807624	RCV005904263
Colon adenocarcinoma	Benign; Likely benign	rs532500568	RCV005869677
Familial cancer of breast	Benign; Likely benign; Conflicting classifications of pathogenicity	rs532500568, rs745754666, rs200156764, rs76401964	RCV005869676 RCV005868572 RCV005896610 RCV005907728
Familial pancreatic carcinoma	Likely benign	rs72807624	RCV005904254
Gastric cancer	Benign; Likely benign	rs745754666, rs72807624	RCV005868576 RCV005904257
Germ cell tumor of testis	Benign	rs2627765	RCV005886787
Glioma susceptibility 1	Benign; Likely benign	rs745754666	RCV005868573
Hereditary ataxia	Uncertain significance	rs773634635, rs143197548	RCV005622137 RCV005622134
Lung cancer	Likely benign	rs72807624	RCV005904261
Lymphoma	Likely benign	rs72807624	RCV005904258
Malignant lymphoma, large B-cell, diffuse	Likely benign	rs72807624	RCV005904255
Malignant tumor of esophagus	Benign; Likely benign; Uncertain significance	rs72930831, rs202243908, rs72807624, rs778119158	RCV005918714 RCV005898000 RCV005904250 RCV005912434
Nonpapillary renal cell carcinoma	Likely benign	rs72807624	RCV005904251
Ovarian cancer	Likely benign	rs72807624	RCV005904253
Sarcoma	Likely benign	rs72807624	RCV005904256
Schizophrenia	Uncertain significance	rs2529502980	RCV002463508
See cases	Benign; Likely benign	rs202243908	RCV002252124
Thymoma	Likely benign	rs72807624	RCV005904260
Uterine carcinosarcoma	Likely benign	rs72807624	RCV005904259
Uterine corpus endometrial carcinoma	Benign; Likely benign	rs532500568, rs745754666, rs72807624	RCV005869678 RCV005868578 RCV005904262
Uveal melanoma	Benign; Likely benign	rs745754666	RCV005868575

Show/Hide Text Mining Associations (25)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Alcoholic Neuropathy	Associate	27759031
Anemia Pernicious	Associate	34145262
Ataxia	Associate	35411967
Carcinoma Hepatocellular	Associate	36232701, 37400627, 39522317
Carcinoma Non Small Cell Lung	Associate	39788504
Chorioretinitis	Associate	25457163
Disease	Associate	27759031
Eye Abnormalities	Associate	25457163
Hearing Loss	Associate	34194829
Hearing Loss Sensorineural	Associate	25457163
Inflammation	Associate	24143183
Intervertebral Disc Degeneration	Associate	33174041
Melanoma	Associate	16055741, 20547861, 24729470
Microcephaly	Associate	25457163
Mitochondrial Diseases	Associate	22411789, 23084291, 24143183, 27759031, 30020492
Mitochondrial Encephalomyopathies	Associate	23084291
Movement Disorders	Associate	23084291
Myopathy with Giant Abnormal Mitochondria	Associate	30020492
Neoplasms	Associate	36232701
Neuroblastoma	Associate	19202553
Nonsyndromic sensorineural hearing loss	Associate	34194829
Respiratory Insufficiency	Associate	27759031
Seizures	Associate	25457163
Spinocerebellar ataxia 25	Associate	35411967
Spinocerebellar Ataxias	Associate	35411967

PNPT1 (polyribonucleotide nucleotidyltransferase 1)