PEA15 (proliferation and apoptosis adaptor protein 15)

Gene

• Entrez ID: 8682
• Gene name: Proliferation and apoptosis adaptor protein 15
• Gene symbol: PEA15
• Synonyms (NCBI Gene): HMAT1, HUMMAT1H, MAT1, MAT1H, PEA-15, PED, PED-PEA15, PED/PEA15
• Chromosome: 1
• Chromosome location: 1q23.2
• Summary: This gene encodes a death effector domain-containing protein that functions as a negative regulator of apoptosis. The encoded protein is an endogenous substrate for protein kinase C. This protein is also overexpressed in type 2 diabetes mellitus, where it

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT004501	hsa-miR-212-3p	qRT-PCR, Luciferase reporter assay, Western blot	20388802
MIRT004502	hsa-miR-34a-5p	Western blot	20388802
MIRT004503	hsa-miR-124-3p	Western blot	20388802
MIRT023321	hsa-miR-122-5p	Microarray	17612493
MIRT004502	hsa-miR-34a-5p	Sequencing	20371350
MIRT036926	hsa-miR-877-3p	CLASH	23622248
MIRT036926	hsa-miR-877-3p	CLASH	23622248
MIRT437647	hsa-miR-155-5p	Microarray, qRT-PCR	22815788
MIRT004502	hsa-miR-34a-5p	Microarray, qRT-PCR	22815788
MIRT725231	hsa-miR-3609	HITS-CLIP	19536157
MIRT725232	hsa-miR-548ah-5p	HITS-CLIP	19536157
MIRT725230	hsa-miR-106a-5p	HITS-CLIP	19536157
MIRT725229	hsa-miR-106b-5p	HITS-CLIP	19536157
MIRT725228	hsa-miR-17-5p	HITS-CLIP	19536157
MIRT725227	hsa-miR-20a-5p	HITS-CLIP	19536157
MIRT725226	hsa-miR-20b-5p	HITS-CLIP	19536157
MIRT725225	hsa-miR-519d-3p	HITS-CLIP	19536157
MIRT725224	hsa-miR-526b-3p	HITS-CLIP	19536157
MIRT725223	hsa-miR-93-5p	HITS-CLIP	19536157
MIRT725222	hsa-miR-4796-3p	HITS-CLIP	19536157
MIRT725221	hsa-miR-4323	HITS-CLIP	19536157
MIRT725220	hsa-miR-3943	HITS-CLIP	19536157
MIRT725219	hsa-miR-6769a-3p	HITS-CLIP	19536157
MIRT725218	hsa-miR-3651	HITS-CLIP	19536157
MIRT725217	hsa-miR-1306-5p	HITS-CLIP	19536157
MIRT725216	hsa-miR-1224-3p	HITS-CLIP	19536157
MIRT725215	hsa-miR-5009-3p	HITS-CLIP	19536157
MIRT610730	hsa-miR-5193	HITS-CLIP	19536157
MIRT610729	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT655308	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT610728	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610727	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610726	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT655309	hsa-miR-493-3p	HITS-CLIP	23824327
MIRT610730	hsa-miR-5193	HITS-CLIP	23824327
MIRT610729	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT655308	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT610728	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610727	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610726	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610730	hsa-miR-5193	HITS-CLIP	23824327
MIRT610729	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610728	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610727	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610726	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610730	hsa-miR-5193	HITS-CLIP	23824327
MIRT610729	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610728	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610727	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610726	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT725231	hsa-miR-3609	HITS-CLIP	19536157
MIRT725232	hsa-miR-548ah-5p	HITS-CLIP	19536157
MIRT725230	hsa-miR-106a-5p	HITS-CLIP	19536157
MIRT725229	hsa-miR-106b-5p	HITS-CLIP	19536157
MIRT725228	hsa-miR-17-5p	HITS-CLIP	19536157
MIRT725227	hsa-miR-20a-5p	HITS-CLIP	19536157
MIRT725226	hsa-miR-20b-5p	HITS-CLIP	19536157
MIRT725225	hsa-miR-519d-3p	HITS-CLIP	19536157
MIRT725224	hsa-miR-526b-3p	HITS-CLIP	19536157
MIRT725223	hsa-miR-93-5p	HITS-CLIP	19536157
MIRT725222	hsa-miR-4796-3p	HITS-CLIP	19536157
MIRT725221	hsa-miR-4323	HITS-CLIP	19536157
MIRT725220	hsa-miR-3943	HITS-CLIP	19536157
MIRT725219	hsa-miR-6769a-3p	HITS-CLIP	19536157
MIRT725218	hsa-miR-3651	HITS-CLIP	19536157
MIRT725217	hsa-miR-1306-5p	HITS-CLIP	19536157
MIRT725216	hsa-miR-1224-3p	HITS-CLIP	19536157
MIRT725215	hsa-miR-5009-3p	HITS-CLIP	19536157
MIRT610730	hsa-miR-5193	HITS-CLIP	19536157
MIRT610729	hsa-miR-660-3p	HITS-CLIP	19536157
MIRT655308	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT610728	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610727	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610726	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT655309	hsa-miR-493-3p	HITS-CLIP	23824327
MIRT610730	hsa-miR-5193	HITS-CLIP	23824327
MIRT610729	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT655308	hsa-miR-3667-3p	HITS-CLIP	23824327
MIRT610728	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610727	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610726	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610730	hsa-miR-5193	HITS-CLIP	23824327
MIRT610729	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610728	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610727	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610726	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT610730	hsa-miR-5193	HITS-CLIP	23824327
MIRT610729	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT610728	hsa-miR-4691-5p	HITS-CLIP	23824327
MIRT610727	hsa-miR-6792-3p	HITS-CLIP	23824327
MIRT610726	hsa-miR-6749-3p	HITS-CLIP	23824327
MIRT1224118	hsa-miR-1	CLIP-seq
MIRT1224119	hsa-miR-1183	CLIP-seq
MIRT1224120	hsa-miR-1236	CLIP-seq
MIRT1224121	hsa-miR-1250	CLIP-seq
MIRT1224122	hsa-miR-1257	CLIP-seq
MIRT1224123	hsa-miR-1266	CLIP-seq
MIRT1224124	hsa-miR-1293	CLIP-seq
MIRT1224125	hsa-miR-1324	CLIP-seq
MIRT1224126	hsa-miR-141	CLIP-seq
MIRT1224127	hsa-miR-149	CLIP-seq
MIRT1224128	hsa-miR-153	CLIP-seq
MIRT1224129	hsa-miR-186	CLIP-seq
MIRT1224130	hsa-miR-1913	CLIP-seq
MIRT1224131	hsa-miR-197	CLIP-seq
MIRT1224132	hsa-miR-1973	CLIP-seq
MIRT1224133	hsa-miR-19a	CLIP-seq
MIRT1224134	hsa-miR-19b	CLIP-seq
MIRT1224135	hsa-miR-200a	CLIP-seq
MIRT1224136	hsa-miR-206	CLIP-seq
MIRT1224137	hsa-miR-2114	CLIP-seq
MIRT1224138	hsa-miR-2116	CLIP-seq
MIRT1224139	hsa-miR-216a	CLIP-seq
MIRT1224140	hsa-miR-217	CLIP-seq
MIRT1224141	hsa-miR-219-2-3p	CLIP-seq
MIRT1224142	hsa-miR-24	CLIP-seq
MIRT1224143	hsa-miR-2964a-3p	CLIP-seq
MIRT1224144	hsa-miR-3064-5p	CLIP-seq
MIRT1224145	hsa-miR-3120-3p	CLIP-seq
MIRT1224146	hsa-miR-3125	CLIP-seq
MIRT1224147	hsa-miR-3127-3p	CLIP-seq
MIRT1224148	hsa-miR-3133	CLIP-seq
MIRT1224149	hsa-miR-3150a-3p	CLIP-seq
MIRT1224150	hsa-miR-3154	CLIP-seq
MIRT1224151	hsa-miR-3155	CLIP-seq
MIRT1224152	hsa-miR-3155b	CLIP-seq
MIRT1224153	hsa-miR-3166	CLIP-seq
MIRT1224154	hsa-miR-3170	CLIP-seq
MIRT1224155	hsa-miR-3173-3p	CLIP-seq
MIRT1224156	hsa-miR-3175	CLIP-seq
MIRT1224157	hsa-miR-3183	CLIP-seq
MIRT1224158	hsa-miR-324-3p	CLIP-seq
MIRT1224159	hsa-miR-325	CLIP-seq
MIRT1224160	hsa-miR-329	CLIP-seq
MIRT1224161	hsa-miR-342-3p	CLIP-seq
MIRT1224162	hsa-miR-342-5p	CLIP-seq
MIRT1224163	hsa-miR-3607-5p	CLIP-seq
MIRT1224164	hsa-miR-362-3p	CLIP-seq
MIRT1224165	hsa-miR-3653	CLIP-seq
MIRT1224166	hsa-miR-3658	CLIP-seq
MIRT1224167	hsa-miR-3664-3p	CLIP-seq
MIRT1224168	hsa-miR-3668	CLIP-seq
MIRT1224169	hsa-miR-3672	CLIP-seq
MIRT1224170	hsa-miR-3685	CLIP-seq
MIRT1224171	hsa-miR-384	CLIP-seq
MIRT1224172	hsa-miR-3916	CLIP-seq
MIRT1224173	hsa-miR-3922-5p	CLIP-seq
MIRT1224174	hsa-miR-3925-3p	CLIP-seq
MIRT1224175	hsa-miR-3928	CLIP-seq
MIRT1224176	hsa-miR-3941	CLIP-seq
MIRT1224177	hsa-miR-3942-5p	CLIP-seq
MIRT1224178	hsa-miR-409-3p	CLIP-seq
MIRT1224179	hsa-miR-412	CLIP-seq
MIRT1224180	hsa-miR-4290	CLIP-seq
MIRT1224181	hsa-miR-4329	CLIP-seq
MIRT1224182	hsa-miR-4418	CLIP-seq
MIRT1224183	hsa-miR-4428	CLIP-seq
MIRT1224184	hsa-miR-4447	CLIP-seq
MIRT1224185	hsa-miR-4450	CLIP-seq
MIRT1224186	hsa-miR-4452	CLIP-seq
MIRT1224187	hsa-miR-4472	CLIP-seq
MIRT1224188	hsa-miR-4474-5p	CLIP-seq
MIRT1224189	hsa-miR-448	CLIP-seq
MIRT1224190	hsa-miR-4481	CLIP-seq
MIRT1224191	hsa-miR-4483	CLIP-seq
MIRT1224192	hsa-miR-4488	CLIP-seq
MIRT1224193	hsa-miR-4497	CLIP-seq
MIRT1224194	hsa-miR-450b-3p	CLIP-seq
MIRT1224195	hsa-miR-4518	CLIP-seq
MIRT1224196	hsa-miR-4651	CLIP-seq
MIRT1224197	hsa-miR-4662a-3p	CLIP-seq
MIRT1224198	hsa-miR-4664-5p	CLIP-seq
MIRT1224199	hsa-miR-4666-5p	CLIP-seq
MIRT1224200	hsa-miR-4677-5p	CLIP-seq
MIRT1224201	hsa-miR-4697-5p	CLIP-seq
MIRT1224202	hsa-miR-4703-3p	CLIP-seq
MIRT1224203	hsa-miR-4703-5p	CLIP-seq
MIRT1224204	hsa-miR-4723-3p	CLIP-seq
MIRT1224205	hsa-miR-4736	CLIP-seq
MIRT1224206	hsa-miR-4745-5p	CLIP-seq
MIRT1224207	hsa-miR-4771	CLIP-seq
MIRT1224208	hsa-miR-4773	CLIP-seq
MIRT1224209	hsa-miR-4794	CLIP-seq
MIRT1224210	hsa-miR-484	CLIP-seq
MIRT1224211	hsa-miR-491-5p	CLIP-seq
MIRT1224212	hsa-miR-509-3-5p	CLIP-seq
MIRT1224213	hsa-miR-509-5p	CLIP-seq
MIRT1224214	hsa-miR-518a-5p	CLIP-seq
MIRT1224215	hsa-miR-520a-5p	CLIP-seq
MIRT1224216	hsa-miR-525-5p	CLIP-seq
MIRT1224217	hsa-miR-527	CLIP-seq
MIRT1224218	hsa-miR-541	CLIP-seq
MIRT1224219	hsa-miR-552	CLIP-seq
MIRT1224220	hsa-miR-570	CLIP-seq
MIRT1224221	hsa-miR-603	CLIP-seq
MIRT1224222	hsa-miR-604	CLIP-seq
MIRT1224223	hsa-miR-608	CLIP-seq
MIRT1224224	hsa-miR-613	CLIP-seq
MIRT1224225	hsa-miR-628-3p	CLIP-seq
MIRT1224226	hsa-miR-638	CLIP-seq
MIRT1224227	hsa-miR-647	CLIP-seq
MIRT1224228	hsa-miR-657	CLIP-seq
MIRT1224229	hsa-miR-766	CLIP-seq
MIRT1224230	hsa-miR-769-3p	CLIP-seq
MIRT1224231	hsa-miR-889	CLIP-seq
MIRT1224232	hsa-miR-939	CLIP-seq
MIRT1224124	hsa-miR-1293	CLIP-seq
MIRT1224144	hsa-miR-3064-5p	CLIP-seq
MIRT1224154	hsa-miR-3170	CLIP-seq
MIRT1552211	hsa-miR-338-5p	CLIP-seq
MIRT1552212	hsa-miR-3665	CLIP-seq
MIRT1552213	hsa-miR-4423-5p	CLIP-seq
MIRT1224184	hsa-miR-4447	CLIP-seq
MIRT1224187	hsa-miR-4472	CLIP-seq
MIRT1224191	hsa-miR-4483	CLIP-seq
MIRT1224192	hsa-miR-4488	CLIP-seq
MIRT1224201	hsa-miR-4697-5p	CLIP-seq
MIRT1224205	hsa-miR-4736	CLIP-seq
MIRT1552214	hsa-miR-4747-5p	CLIP-seq
MIRT1552215	hsa-miR-4774-3p	CLIP-seq
MIRT1224222	hsa-miR-604	CLIP-seq
MIRT1224227	hsa-miR-647	CLIP-seq
MIRT1224228	hsa-miR-657	CLIP-seq
MIRT1552216	hsa-miR-940	CLIP-seq
MIRT1224120	hsa-miR-1236	CLIP-seq
MIRT1556779	hsa-miR-1915	CLIP-seq
MIRT1556780	hsa-miR-2115	CLIP-seq
MIRT1224148	hsa-miR-3133	CLIP-seq
MIRT1224149	hsa-miR-3150a-3p	CLIP-seq
MIRT1224153	hsa-miR-3166	CLIP-seq
MIRT1224154	hsa-miR-3170	CLIP-seq
MIRT1224156	hsa-miR-3175	CLIP-seq
MIRT1556781	hsa-miR-3184	CLIP-seq
MIRT1552212	hsa-miR-3665	CLIP-seq
MIRT1556782	hsa-miR-3689d	CLIP-seq
MIRT1556783	hsa-miR-3692	CLIP-seq
MIRT1556784	hsa-miR-4266	CLIP-seq
MIRT1556785	hsa-miR-4268	CLIP-seq
MIRT1556786	hsa-miR-4457	CLIP-seq
MIRT1556787	hsa-miR-4474-3p	CLIP-seq
MIRT1556788	hsa-miR-4496	CLIP-seq
MIRT1556789	hsa-miR-4505	CLIP-seq
MIRT1556790	hsa-miR-4695-5p	CLIP-seq
MIRT1556791	hsa-miR-4713-5p	CLIP-seq
MIRT1556792	hsa-miR-4728-5p	CLIP-seq
MIRT1552214	hsa-miR-4747-5p	CLIP-seq
MIRT1556793	hsa-miR-4779	CLIP-seq
MIRT1224211	hsa-miR-491-5p	CLIP-seq
MIRT1556794	hsa-miR-513b	CLIP-seq
MIRT1556795	hsa-miR-516a-3p	CLIP-seq
MIRT1556796	hsa-miR-544	CLIP-seq
MIRT1556797	hsa-miR-635	CLIP-seq
MIRT1224228	hsa-miR-657	CLIP-seq
MIRT1224232	hsa-miR-939	CLIP-seq
MIRT1224119	hsa-miR-1183	CLIP-seq
MIRT2065338	hsa-miR-1208	CLIP-seq
MIRT1224120	hsa-miR-1236	CLIP-seq
MIRT2065339	hsa-miR-124	CLIP-seq
MIRT1224121	hsa-miR-1250	CLIP-seq
MIRT2065340	hsa-miR-132	CLIP-seq
MIRT1224125	hsa-miR-1324	CLIP-seq
MIRT1224126	hsa-miR-141	CLIP-seq
MIRT1224127	hsa-miR-149	CLIP-seq
MIRT1224132	hsa-miR-1973	CLIP-seq
MIRT1224133	hsa-miR-19a	CLIP-seq
MIRT1224134	hsa-miR-19b	CLIP-seq
MIRT1224135	hsa-miR-200a	CLIP-seq
MIRT1224137	hsa-miR-2114	CLIP-seq
MIRT1556780	hsa-miR-2115	CLIP-seq
MIRT2065341	hsa-miR-212	CLIP-seq
MIRT1224139	hsa-miR-216a	CLIP-seq
MIRT1224141	hsa-miR-219-2-3p	CLIP-seq
MIRT1224143	hsa-miR-2964a-3p	CLIP-seq
MIRT1224144	hsa-miR-3064-5p	CLIP-seq
MIRT1224145	hsa-miR-3120-3p	CLIP-seq
MIRT1224153	hsa-miR-3166	CLIP-seq
MIRT1224154	hsa-miR-3170	CLIP-seq
MIRT2065342	hsa-miR-338-3p	CLIP-seq
MIRT1224161	hsa-miR-342-3p	CLIP-seq
MIRT1224162	hsa-miR-342-5p	CLIP-seq
MIRT1224167	hsa-miR-3664-3p	CLIP-seq
MIRT2065343	hsa-miR-3680	CLIP-seq
MIRT1556783	hsa-miR-3692	CLIP-seq
MIRT2065344	hsa-miR-3714	CLIP-seq
MIRT2065345	hsa-miR-3910	CLIP-seq
MIRT1224173	hsa-miR-3922-5p	CLIP-seq
MIRT1224177	hsa-miR-3942-5p	CLIP-seq
MIRT1224182	hsa-miR-4418	CLIP-seq
MIRT1224185	hsa-miR-4450	CLIP-seq
MIRT1224186	hsa-miR-4452	CLIP-seq
MIRT1556789	hsa-miR-4505	CLIP-seq
MIRT2065346	hsa-miR-4530	CLIP-seq
MIRT1224196	hsa-miR-4651	CLIP-seq
MIRT1224197	hsa-miR-4662a-3p	CLIP-seq
MIRT1224198	hsa-miR-4664-5p	CLIP-seq
MIRT1224202	hsa-miR-4703-3p	CLIP-seq
MIRT1224203	hsa-miR-4703-5p	CLIP-seq
MIRT1224205	hsa-miR-4736	CLIP-seq
MIRT1552214	hsa-miR-4747-5p	CLIP-seq
MIRT1224207	hsa-miR-4771	CLIP-seq
MIRT1224208	hsa-miR-4773	CLIP-seq
MIRT1552215	hsa-miR-4774-3p	CLIP-seq
MIRT1224209	hsa-miR-4794	CLIP-seq
MIRT1224211	hsa-miR-491-5p	CLIP-seq
MIRT2065347	hsa-miR-493	CLIP-seq
MIRT2065348	hsa-miR-506	CLIP-seq
MIRT1224212	hsa-miR-509-3-5p	CLIP-seq
MIRT1224213	hsa-miR-509-5p	CLIP-seq
MIRT1556795	hsa-miR-516a-3p	CLIP-seq
MIRT1224214	hsa-miR-518a-5p	CLIP-seq
MIRT1224217	hsa-miR-527	CLIP-seq
MIRT1556796	hsa-miR-544	CLIP-seq
MIRT1224220	hsa-miR-570	CLIP-seq
MIRT1224223	hsa-miR-608	CLIP-seq
MIRT2065349	hsa-miR-615-5p	CLIP-seq
MIRT2065350	hsa-miR-622	CLIP-seq
MIRT1224226	hsa-miR-638	CLIP-seq
MIRT2065351	hsa-miR-668	CLIP-seq
MIRT1552216	hsa-miR-940	CLIP-seq
MIRT2293159	hsa-miR-103a	CLIP-seq
MIRT1224119	hsa-miR-1183	CLIP-seq
MIRT2065338	hsa-miR-1208	CLIP-seq
MIRT2293160	hsa-miR-1237	CLIP-seq
MIRT2065339	hsa-miR-124	CLIP-seq
MIRT2293161	hsa-miR-1248	CLIP-seq
MIRT1224121	hsa-miR-1250	CLIP-seq
MIRT2293162	hsa-miR-1258	CLIP-seq
MIRT2293163	hsa-miR-1260	CLIP-seq
MIRT2293164	hsa-miR-1260b	CLIP-seq
MIRT2293165	hsa-miR-1280	CLIP-seq
MIRT1224124	hsa-miR-1293	CLIP-seq
MIRT2293166	hsa-miR-1303	CLIP-seq
MIRT2293167	hsa-miR-130a	CLIP-seq
MIRT2293168	hsa-miR-130b	CLIP-seq
MIRT2065340	hsa-miR-132	CLIP-seq
MIRT1224125	hsa-miR-1324	CLIP-seq
MIRT1224126	hsa-miR-141	CLIP-seq
MIRT1224127	hsa-miR-149	CLIP-seq
MIRT2293169	hsa-miR-185	CLIP-seq
MIRT2293170	hsa-miR-188-3p	CLIP-seq
MIRT1224131	hsa-miR-197	CLIP-seq
MIRT1224132	hsa-miR-1973	CLIP-seq
MIRT1224133	hsa-miR-19a	CLIP-seq
MIRT1224134	hsa-miR-19b	CLIP-seq
MIRT1224135	hsa-miR-200a	CLIP-seq
MIRT1224137	hsa-miR-2114	CLIP-seq
MIRT1224138	hsa-miR-2116	CLIP-seq
MIRT2065341	hsa-miR-212	CLIP-seq
MIRT1224139	hsa-miR-216a	CLIP-seq
MIRT1224141	hsa-miR-219-2-3p	CLIP-seq
MIRT2293171	hsa-miR-2682	CLIP-seq
MIRT1224143	hsa-miR-2964a-3p	CLIP-seq
MIRT2293172	hsa-miR-301a	CLIP-seq
MIRT2293173	hsa-miR-301b	CLIP-seq
MIRT1224144	hsa-miR-3064-5p	CLIP-seq
MIRT2293174	hsa-miR-3117-3p	CLIP-seq
MIRT1224145	hsa-miR-3120-3p	CLIP-seq
MIRT1224149	hsa-miR-3150a-3p	CLIP-seq
MIRT1224153	hsa-miR-3166	CLIP-seq
MIRT1224154	hsa-miR-3170	CLIP-seq
MIRT1224155	hsa-miR-3173-3p	CLIP-seq
MIRT1224156	hsa-miR-3175	CLIP-seq
MIRT2293175	hsa-miR-3176	CLIP-seq
MIRT1556781	hsa-miR-3184	CLIP-seq
MIRT1224160	hsa-miR-329	CLIP-seq
MIRT2065342	hsa-miR-338-3p	CLIP-seq
MIRT1224161	hsa-miR-342-3p	CLIP-seq
MIRT1224162	hsa-miR-342-5p	CLIP-seq
MIRT1224164	hsa-miR-362-3p	CLIP-seq
MIRT1552212	hsa-miR-3665	CLIP-seq
MIRT2293176	hsa-miR-3666	CLIP-seq
MIRT2065343	hsa-miR-3680	CLIP-seq
MIRT1556782	hsa-miR-3689d	CLIP-seq
MIRT2065344	hsa-miR-3714	CLIP-seq
MIRT2065345	hsa-miR-3910	CLIP-seq
MIRT2293177	hsa-miR-3922-3p	CLIP-seq
MIRT1224173	hsa-miR-3922-5p	CLIP-seq
MIRT2293178	hsa-miR-3934	CLIP-seq
MIRT2293179	hsa-miR-3936	CLIP-seq
MIRT2293180	hsa-miR-3939	CLIP-seq
MIRT1224176	hsa-miR-3941	CLIP-seq
MIRT1224177	hsa-miR-3942-5p	CLIP-seq
MIRT1224179	hsa-miR-412	CLIP-seq
MIRT2293181	hsa-miR-4261	CLIP-seq
MIRT1224180	hsa-miR-4290	CLIP-seq
MIRT2293182	hsa-miR-4295	CLIP-seq
MIRT2293183	hsa-miR-4305	CLIP-seq
MIRT2293184	hsa-miR-4306	CLIP-seq
MIRT1224182	hsa-miR-4418	CLIP-seq
MIRT2293185	hsa-miR-4424	CLIP-seq
MIRT1224183	hsa-miR-4428	CLIP-seq
MIRT2293186	hsa-miR-4433	CLIP-seq
MIRT1224184	hsa-miR-4447	CLIP-seq
MIRT1224185	hsa-miR-4450	CLIP-seq
MIRT1224186	hsa-miR-4452	CLIP-seq
MIRT1556786	hsa-miR-4457	CLIP-seq
MIRT2293187	hsa-miR-4459	CLIP-seq
MIRT2293188	hsa-miR-4464	CLIP-seq
MIRT1224187	hsa-miR-4472	CLIP-seq
MIRT1224190	hsa-miR-4481	CLIP-seq
MIRT1224191	hsa-miR-4483	CLIP-seq
MIRT1224192	hsa-miR-4488	CLIP-seq
MIRT1556788	hsa-miR-4496	CLIP-seq
MIRT1224193	hsa-miR-4497	CLIP-seq
MIRT2293189	hsa-miR-449c	CLIP-seq
MIRT1556789	hsa-miR-4505	CLIP-seq
MIRT1224194	hsa-miR-450b-3p	CLIP-seq
MIRT2065346	hsa-miR-4530	CLIP-seq
MIRT2293190	hsa-miR-454	CLIP-seq
MIRT2293191	hsa-miR-455-3p	CLIP-seq
MIRT2293192	hsa-miR-4644	CLIP-seq
MIRT1224196	hsa-miR-4651	CLIP-seq
MIRT2293193	hsa-miR-4653-3p	CLIP-seq
MIRT1224197	hsa-miR-4662a-3p	CLIP-seq
MIRT1224198	hsa-miR-4664-5p	CLIP-seq
MIRT2293194	hsa-miR-4666-3p	CLIP-seq
MIRT1224200	hsa-miR-4677-5p	CLIP-seq
MIRT2293195	hsa-miR-4682	CLIP-seq
MIRT1556790	hsa-miR-4695-5p	CLIP-seq
MIRT1224201	hsa-miR-4697-5p	CLIP-seq
MIRT1224202	hsa-miR-4703-3p	CLIP-seq
MIRT1224203	hsa-miR-4703-5p	CLIP-seq
MIRT2293196	hsa-miR-4705	CLIP-seq
MIRT2293197	hsa-miR-4709-5p	CLIP-seq
MIRT2293198	hsa-miR-4714-3p	CLIP-seq
MIRT2293199	hsa-miR-4722-5p	CLIP-seq
MIRT1556792	hsa-miR-4728-5p	CLIP-seq
MIRT2293200	hsa-miR-4731-5p	CLIP-seq
MIRT1224205	hsa-miR-4736	CLIP-seq
MIRT1224206	hsa-miR-4745-5p	CLIP-seq
MIRT1552214	hsa-miR-4747-5p	CLIP-seq
MIRT2293201	hsa-miR-4748	CLIP-seq
MIRT1224207	hsa-miR-4771	CLIP-seq
MIRT1224208	hsa-miR-4773	CLIP-seq
MIRT2293202	hsa-miR-4778-3p	CLIP-seq
MIRT1224209	hsa-miR-4794	CLIP-seq
MIRT2293203	hsa-miR-4802-3p	CLIP-seq
MIRT2293204	hsa-miR-485-5p	CLIP-seq
MIRT1224211	hsa-miR-491-5p	CLIP-seq
MIRT2065348	hsa-miR-506	CLIP-seq
MIRT1224212	hsa-miR-509-3-5p	CLIP-seq
MIRT1224213	hsa-miR-509-5p	CLIP-seq
MIRT1556794	hsa-miR-513b	CLIP-seq
MIRT1224214	hsa-miR-518a-5p	CLIP-seq
MIRT1224217	hsa-miR-527	CLIP-seq
MIRT2293205	hsa-miR-532-3p	CLIP-seq
MIRT1224218	hsa-miR-541	CLIP-seq
MIRT1224219	hsa-miR-552	CLIP-seq
MIRT1224220	hsa-miR-570	CLIP-seq
MIRT1224221	hsa-miR-603	CLIP-seq
MIRT1224222	hsa-miR-604	CLIP-seq
MIRT1224223	hsa-miR-608	CLIP-seq
MIRT2065349	hsa-miR-615-5p	CLIP-seq
MIRT2065350	hsa-miR-622	CLIP-seq
MIRT1556797	hsa-miR-635	CLIP-seq
MIRT1224226	hsa-miR-638	CLIP-seq
MIRT1224227	hsa-miR-647	CLIP-seq
MIRT2065351	hsa-miR-668	CLIP-seq
MIRT1224230	hsa-miR-769-3p	CLIP-seq
MIRT2293206	hsa-miR-933	CLIP-seq
MIRT1224232	hsa-miR-939	CLIP-seq
MIRT1552216	hsa-miR-940	CLIP-seq
MIRT1224139	hsa-miR-216a	CLIP-seq
MIRT1224145	hsa-miR-3120-3p	CLIP-seq
MIRT1224153	hsa-miR-3166	CLIP-seq
MIRT1224155	hsa-miR-3173-3p	CLIP-seq
MIRT1224161	hsa-miR-342-3p	CLIP-seq
MIRT1224177	hsa-miR-3942-5p	CLIP-seq
MIRT1224183	hsa-miR-4428	CLIP-seq
MIRT1224203	hsa-miR-4703-5p	CLIP-seq
MIRT1224211	hsa-miR-491-5p	CLIP-seq
MIRT2432096	hsa-miR-1206	CLIP-seq
MIRT2432097	hsa-miR-1283	CLIP-seq
MIRT1224124	hsa-miR-1293	CLIP-seq
MIRT2293170	hsa-miR-188-3p	CLIP-seq
MIRT1224139	hsa-miR-216a	CLIP-seq
MIRT1224145	hsa-miR-3120-3p	CLIP-seq
MIRT1224155	hsa-miR-3173-3p	CLIP-seq
MIRT1224161	hsa-miR-342-3p	CLIP-seq
MIRT2432098	hsa-miR-3545-3p	CLIP-seq
MIRT2432099	hsa-miR-3675-3p	CLIP-seq
MIRT2432100	hsa-miR-3679-3p	CLIP-seq
MIRT1224177	hsa-miR-3942-5p	CLIP-seq
MIRT1224183	hsa-miR-4428	CLIP-seq
MIRT1224188	hsa-miR-4474-5p	CLIP-seq
MIRT1224190	hsa-miR-4481	CLIP-seq
MIRT1224191	hsa-miR-4483	CLIP-seq
MIRT1224197	hsa-miR-4662a-3p	CLIP-seq
MIRT1224203	hsa-miR-4703-5p	CLIP-seq
MIRT1224205	hsa-miR-4736	CLIP-seq
MIRT1224206	hsa-miR-4745-5p	CLIP-seq
MIRT2432101	hsa-miR-4760-5p	CLIP-seq
MIRT1224218	hsa-miR-541	CLIP-seq
MIRT1224228	hsa-miR-657	CLIP-seq
MIRT2065338	hsa-miR-1208	CLIP-seq
MIRT2293161	hsa-miR-1248	CLIP-seq
MIRT2591217	hsa-miR-1256	CLIP-seq
MIRT1224122	hsa-miR-1257	CLIP-seq
MIRT2293162	hsa-miR-1258	CLIP-seq
MIRT2293163	hsa-miR-1260	CLIP-seq
MIRT2293164	hsa-miR-1260b	CLIP-seq
MIRT2591218	hsa-miR-1269	CLIP-seq
MIRT2591219	hsa-miR-1269b	CLIP-seq
MIRT2293165	hsa-miR-1280	CLIP-seq
MIRT2591220	hsa-miR-129-5p	CLIP-seq
MIRT1224140	hsa-miR-217	CLIP-seq
MIRT2591221	hsa-miR-28-3p	CLIP-seq
MIRT2293174	hsa-miR-3117-3p	CLIP-seq
MIRT1224146	hsa-miR-3125	CLIP-seq
MIRT1224147	hsa-miR-3127-3p	CLIP-seq
MIRT2293175	hsa-miR-3176	CLIP-seq
MIRT1224163	hsa-miR-3607-5p	CLIP-seq
MIRT2591222	hsa-miR-3614-3p	CLIP-seq
MIRT1224165	hsa-miR-3653	CLIP-seq
MIRT1224166	hsa-miR-3658	CLIP-seq
MIRT1224168	hsa-miR-3668	CLIP-seq
MIRT1224169	hsa-miR-3672	CLIP-seq
MIRT2591223	hsa-miR-3688-5p	CLIP-seq
MIRT2591224	hsa-miR-3908	CLIP-seq
MIRT1224172	hsa-miR-3916	CLIP-seq
MIRT2293177	hsa-miR-3922-3p	CLIP-seq
MIRT1224175	hsa-miR-3928	CLIP-seq
MIRT2293179	hsa-miR-3936	CLIP-seq
MIRT2293180	hsa-miR-3939	CLIP-seq
MIRT1224177	hsa-miR-3942-5p	CLIP-seq
MIRT1224178	hsa-miR-409-3p	CLIP-seq
MIRT2591225	hsa-miR-4252	CLIP-seq
MIRT2591226	hsa-miR-4287	CLIP-seq
MIRT2293183	hsa-miR-4305	CLIP-seq
MIRT2591227	hsa-miR-4307	CLIP-seq
MIRT2591228	hsa-miR-4318	CLIP-seq
MIRT2591229	hsa-miR-4420	CLIP-seq
MIRT2591230	hsa-miR-4520b-3p	CLIP-seq
MIRT2591231	hsa-miR-4529-3p	CLIP-seq
MIRT2591232	hsa-miR-4685-3p	CLIP-seq
MIRT1224203	hsa-miR-4703-5p	CLIP-seq
MIRT2591233	hsa-miR-4727-5p	CLIP-seq
MIRT2591234	hsa-miR-4766-3p	CLIP-seq
MIRT2591235	hsa-miR-4769-3p	CLIP-seq
MIRT2293205	hsa-miR-532-3p	CLIP-seq
MIRT1224218	hsa-miR-541	CLIP-seq
MIRT2591236	hsa-miR-556-5p	CLIP-seq
MIRT2591237	hsa-miR-610	CLIP-seq
MIRT2591238	hsa-miR-874	CLIP-seq
MIRT2293206	hsa-miR-933	CLIP-seq
MIRT2065338	hsa-miR-1208	CLIP-seq
MIRT2293161	hsa-miR-1248	CLIP-seq
MIRT2591217	hsa-miR-1256	CLIP-seq
MIRT1224122	hsa-miR-1257	CLIP-seq
MIRT2293162	hsa-miR-1258	CLIP-seq
MIRT2591218	hsa-miR-1269	CLIP-seq
MIRT2591219	hsa-miR-1269b	CLIP-seq
MIRT2591220	hsa-miR-129-5p	CLIP-seq
MIRT1224140	hsa-miR-217	CLIP-seq
MIRT2591221	hsa-miR-28-3p	CLIP-seq
MIRT2293174	hsa-miR-3117-3p	CLIP-seq
MIRT1224146	hsa-miR-3125	CLIP-seq
MIRT1224147	hsa-miR-3127-3p	CLIP-seq
MIRT1224163	hsa-miR-3607-5p	CLIP-seq
MIRT2591222	hsa-miR-3614-3p	CLIP-seq
MIRT1224165	hsa-miR-3653	CLIP-seq
MIRT1224166	hsa-miR-3658	CLIP-seq
MIRT1224168	hsa-miR-3668	CLIP-seq
MIRT1224169	hsa-miR-3672	CLIP-seq
MIRT2591223	hsa-miR-3688-5p	CLIP-seq
MIRT2591224	hsa-miR-3908	CLIP-seq
MIRT1224172	hsa-miR-3916	CLIP-seq
MIRT1224175	hsa-miR-3928	CLIP-seq
MIRT2293179	hsa-miR-3936	CLIP-seq
MIRT2293180	hsa-miR-3939	CLIP-seq
MIRT1224177	hsa-miR-3942-5p	CLIP-seq
MIRT1224178	hsa-miR-409-3p	CLIP-seq
MIRT2591225	hsa-miR-4252	CLIP-seq
MIRT2591226	hsa-miR-4287	CLIP-seq
MIRT2293183	hsa-miR-4305	CLIP-seq
MIRT2591227	hsa-miR-4307	CLIP-seq
MIRT2591228	hsa-miR-4318	CLIP-seq
MIRT2591229	hsa-miR-4420	CLIP-seq
MIRT2591230	hsa-miR-4520b-3p	CLIP-seq
MIRT2591231	hsa-miR-4529-3p	CLIP-seq
MIRT2591232	hsa-miR-4685-3p	CLIP-seq
MIRT1224203	hsa-miR-4703-5p	CLIP-seq
MIRT2591233	hsa-miR-4727-5p	CLIP-seq
MIRT2591234	hsa-miR-4766-3p	CLIP-seq
MIRT2591235	hsa-miR-4769-3p	CLIP-seq
MIRT2591236	hsa-miR-556-5p	CLIP-seq
MIRT2591237	hsa-miR-610	CLIP-seq
MIRT2293206	hsa-miR-933	CLIP-seq

Transcription factors

Transcription factor	Regulation	Reference
RUNX3	Repression	17956589

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000165	Process	MAPK cascade	IEA
GO:0005515	Function	Protein binding	IPI	10442631, 17255949, 21044950, 21900206, 32296183, 33961781
GO:0005654	Component	Nucleoplasm	IDA
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005875	Component	Microtubule associated complex	NAS	8662970
GO:0006915	Process	Apoptotic process	IEA
GO:0042981	Process	Regulation of apoptotic process	IEA
GO:0046325	Process	Negative regulation of D-glucose import	IDA	9670003
GO:1902042	Process	Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	IBA
GO:1902042	Process	Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	IDA	10442631
GO:1902042	Process	Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	IEA
GO:1902042	Process	Negative regulation of extrinsic apoptotic signaling pathway via death domain receptors	IEA
GO:1902043	Process	Positive regulation of extrinsic apoptotic signaling pathway via death domain receptors	IEA

Other IDs

• MIM: 603434
• HGNC: 8822
• e!Ensembl: ENSG00000162734

Protein

• UniProt ID: Q15121
• Protein name: Astrocytic phosphoprotein PEA-15 (15 kDa phosphoprotein enriched in astrocytes) (Phosphoprotein enriched in diabetes) (PED)
• Protein function: Blocks Ras-mediated inhibition of integrin activation and modulates the ERK MAP kinase cascade. Inhibits RPS6KA3 activities by retaining it in the cytoplasm (By similarity). Inhibits both TNFRSF6- and TNFRSF1A-mediated CASP8 activity and apoptos
• PDB: 4IZ5, 4IZA, 6P6B, 6P6C
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF01335	DED	4 → 85	Death effector domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Ubiquitously expressed. Most abundant in tissues such as heart, brain, muscle and adipose tissue which utilize glucose as an energy source. Lower expression in glucose-producing tissues. Higher levels of expression are found in tissues
• Sequence:

  MAEYGTLLQDLTNNITLEDLEQLKSACKEDIPSEKSEEITTGSAWFSFLESHNKLDKDNL
  SYIEHIFEISRRPDLLTMVVDYRTRVLKISEEDELDTKLTRIPSAKKYKDIIRQPSEEEI
  IKLAPPPKKA

• Sequence length: 130

Pathways

Reactome:

RAF-independent MAPK1/3 activation
RAF/MAP kinase cascade

Associated diseases

Evidence Score:

• ★☆☆☆☆  Gene-disease association found in Text Mining only
• ★★☆☆☆  Found in Text Mining and Unknown/Other Associations
• ★★★☆☆  Reported in Unknown/Other Associations across ≥2 Sources
• ★★★★☆  ClinVar: Pathogenic/Likely Pathogenic (<5 Variants)
• ★★★★★  ClinVar: Pathogenic/Likely Pathogenic (≥5 Variants)

Unknown / Other Associations
Phenotype Name	Clinical Significance	Source	Evidence Score
MAJOR DEPRESSIVE DISORDER	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations
UNIPOLAR DEPRESSION	—	Disgenet	★★☆☆☆ Found in Text Mining + Unknown/Other Associations

Associations from Text Mining
Disease Name	Relationship Type	References	Evidence Score
Adenoma	Associate	23604467	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Associate	23543364, 24584939, 34907034	★☆☆☆☆ Found in Text Mining only
Breast Neoplasms	Inhibit	25796184	★☆☆☆☆ Found in Text Mining only
Carcinogenesis	Inhibit	25796184	★☆☆☆☆ Found in Text Mining only
Carcinoma Hepatocellular	Associate	29072691, 30981109	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms	Associate	28936799, 33787596	★☆☆☆☆ Found in Text Mining only
Colorectal Neoplasms Hereditary Nonpolyposis	Associate	23604467	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus	Associate	20452983	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Associate	32993798, 35271662	★☆☆☆☆ Found in Text Mining only
Diabetes Mellitus Type 2	Stimulate	9670003	★☆☆☆☆ Found in Text Mining only
Down Syndrome	Inhibit	30763715	★☆☆☆☆ Found in Text Mining only
Glioblastoma	Associate	19432816	★☆☆☆☆ Found in Text Mining only
Glioma	Associate	20452983, 26470725	★☆☆☆☆ Found in Text Mining only
Insulin Resistance	Associate	9670003	★☆☆☆☆ Found in Text Mining only
Leukemia	Associate	19539371	★☆☆☆☆ Found in Text Mining only
Neoplasms	Associate	21895963, 28936799, 33246486	★☆☆☆☆ Found in Text Mining only
Ovarian Neoplasms	Associate	19010903, 23543364, 32102425, 33246486	★☆☆☆☆ Found in Text Mining only
Sarcopenia	Associate	35271662	★☆☆☆☆ Found in Text Mining only
Thyroid Neoplasms	Associate	16452205	★☆☆☆☆ Found in Text Mining only
Triple Negative Breast Neoplasms	Associate	25796184	★☆☆☆☆ Found in Text Mining only