DDX3Y (DEAD-box helicase 3 Y-linked)
|
Gene
Gene information from NCBI Gene database.
|
|
| Entrez ID | 8653 |
| Gene name | DEAD-box helicase 3 Y-linked |
| Gene symbol | DDX3Y |
| Synonyms (NCBI Gene) |
DBY
|
| Chromosome | Y |
| Chromosome location | Yq11.221 |
| Summary | The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, |
|
miRNA
miRNA information provided by mirtarbase database.
302
|
|||||||||||||||||||||||||
|
|||||||||||||||||||||||||
|
Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
21
|
|||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||
|
Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
|
|||||||
|
|||||||
|
Protein
Protein information from UniProt database.
|
||||||||||||||||
|
UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
|
O15523 | |||||||||||||||
| Protein name | ATP-dependent RNA helicase DDX3Y (EC 3.6.4.13) (DEAD box protein 3, Y-chromosomal) | |||||||||||||||
| Protein function | Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). | |||||||||||||||
| Family and domains |
Pfam
|
|||||||||||||||
| Tissue specificity | TISSUE SPECIFICITY: Widely expressed at the mRNA level, with highest levels in testis (PubMed:9381176). Testis-specific (at protein level). Expressed predominantly in spermatogonia, but occasionally detected in some pre-leptotene/leptotene spermatocytes ( | |||||||||||||||
| Sequence |
|
|||||||||||||||
| Sequence length | 660 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
|
Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
5
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||
|
|||||||||||||||||||||||||||||||||||||