DDX3Y (DEAD-box helicase 3 Y-linked)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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8653 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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DEAD-box helicase 3 Y-linked |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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DDX3Y |
Synonyms (NCBI Gene)
Gene synonyms aliases
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DBY |
Chromosome
Chromosome number
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Y |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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Yq11.221 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene is a member of the DEAD-box RNA helicase family, characterized by nine conserved motifs, included the conserved Asp-Glu-Ala-Asp (DEAD) motif. These motifs are thought to be involved in ATP binding, hydrolysis, RNA binding, |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | O15523 | |||||||||||||||
Protein name | ATP-dependent RNA helicase DDX3Y (EC 3.6.4.13) (DEAD box protein 3, Y-chromosomal) | |||||||||||||||
Protein function | Probable ATP-dependent RNA helicase. During immune response, may enhance IFNB1 expression via IRF3/IRF7 pathway (By similarity). | |||||||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Widely expressed at the mRNA level, with highest levels in testis (PubMed:9381176). Testis-specific (at protein level). Expressed predominantly in spermatogonia, but occasionally detected in some pre-leptotene/leptotene spermatocytes ( | |||||||||||||||
Sequence |
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Sequence length | 660 | |||||||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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