KCNK5 (potassium two pore domain channel subfamily K member 5)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 8645 |
| Gene name | Potassium two pore domain channel subfamily K member 5 |
| Gene symbol | KCNK5 |
| Synonyms (NCBI Gene) |
K2p5.1KCNK5bTASK-2TASK2
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| Chromosome | 6 |
| Chromosome location | 6p21.2 |
| Summary | This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is hi |
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miRNA
miRNA information provided by mirtarbase database.
510
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
25
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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O95279 | |||||||||||||||
| Protein name | Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2) | |||||||||||||||
| Protein function | K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens the gate | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts (PubMed:9812978). Not expressed in proximal tubules or glomeruli (P | |||||||||||||||
| Sequence |
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| Sequence length | 499 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
3
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