KCNK5 (potassium two pore domain channel subfamily K member 5)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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8645 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Potassium two pore domain channel subfamily K member 5 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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KCNK5 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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K2p5.1, KCNK5b, TASK-2, TASK2 |
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Chromosome
Chromosome number
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6 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6p21.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes one of the members of the superfamily of potassium channel proteins containing two pore-forming P domains. The message for this gene is mainly expressed in the cortical distal tubules and collecting ducts of the kidney. The protein is hi |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | O95279 | |||||||||||||||
| Protein name | Potassium channel subfamily K member 5 (Acid-sensitive potassium channel protein TASK-2) (TWIK-related acid-sensitive K(+) channel 2) | |||||||||||||||
| Protein function | K(+) channel that conducts voltage-dependent outward rectifying currents upon membrane depolarization. Voltage sensing is coupled to K(+) electrochemical gradient in an 'ion flux gating' mode where outward but not inward ion flow opens the gate | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Abundant expression in kidney, also detected in liver, placenta and small intestine. In the kidney, expression is restricted to the distal tubules and collecting ducts (PubMed:9812978). Not expressed in proximal tubules or glomeruli (P | |||||||||||||||
| Sequence |
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| Sequence length | 499 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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