Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Gene ontology Other IDs Protein
Entrez ID	8538
Gene name	BARX homeobox 2
Gene symbol	BARX2
Synonyms (NCBI Gene)	-
Chromosome	11
Chromosome location	11q24.3
Summary	This gene encodes a member of the homeobox transcription factor family. A highly related protein in mouse has been shown to influence cellular processes that control cell adhesion and remodeling of the actin cytoskeleton in myoblast fusion and chondrogene

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miRTarBase ID	miRNA	Experiments	Reference
MIRT017365	hsa-miR-335-5p	Microarray	18185580
MIRT039194	hsa-miR-769-5p	CLASH	23622248
MIRT815925	hsa-miR-1225-5p	CLIP-seq
MIRT815926	hsa-miR-124	CLIP-seq
MIRT815927	hsa-miR-1273d	CLIP-seq
MIRT815928	hsa-miR-1285	CLIP-seq
MIRT815929	hsa-miR-183	CLIP-seq
MIRT815930	hsa-miR-185	CLIP-seq
MIRT815931	hsa-miR-187	CLIP-seq
MIRT815932	hsa-miR-193a-5p	CLIP-seq
MIRT815933	hsa-miR-21	CLIP-seq
MIRT815934	hsa-miR-217	CLIP-seq
MIRT815935	hsa-miR-3064-5p	CLIP-seq
MIRT815936	hsa-miR-3127-5p	CLIP-seq
MIRT815937	hsa-miR-3146	CLIP-seq
MIRT815938	hsa-miR-3158-3p	CLIP-seq
MIRT815939	hsa-miR-3187-5p	CLIP-seq
MIRT815940	hsa-miR-33a	CLIP-seq
MIRT815941	hsa-miR-33b	CLIP-seq
MIRT815942	hsa-miR-361-5p	CLIP-seq
MIRT815943	hsa-miR-3692	CLIP-seq
MIRT815944	hsa-miR-374a	CLIP-seq
MIRT815945	hsa-miR-374b	CLIP-seq
MIRT815946	hsa-miR-3914	CLIP-seq
MIRT815947	hsa-miR-3945	CLIP-seq
MIRT815948	hsa-miR-4253	CLIP-seq
MIRT815949	hsa-miR-4257	CLIP-seq
MIRT815950	hsa-miR-4270	CLIP-seq
MIRT815951	hsa-miR-4277	CLIP-seq
MIRT815952	hsa-miR-4306	CLIP-seq
MIRT815953	hsa-miR-4327	CLIP-seq
MIRT815954	hsa-miR-4419a	CLIP-seq
MIRT815955	hsa-miR-4433	CLIP-seq
MIRT815956	hsa-miR-4436b-5p	CLIP-seq
MIRT815957	hsa-miR-4441	CLIP-seq
MIRT815958	hsa-miR-4446-3p	CLIP-seq
MIRT815959	hsa-miR-4459	CLIP-seq
MIRT815960	hsa-miR-4468	CLIP-seq
MIRT815961	hsa-miR-4506	CLIP-seq
MIRT815962	hsa-miR-4510	CLIP-seq
MIRT815963	hsa-miR-4632	CLIP-seq
MIRT815964	hsa-miR-4633-5p	CLIP-seq
MIRT815965	hsa-miR-4644	CLIP-seq
MIRT815966	hsa-miR-4686	CLIP-seq
MIRT815967	hsa-miR-4711-3p	CLIP-seq
MIRT815968	hsa-miR-4729	CLIP-seq
MIRT815969	hsa-miR-4768-3p	CLIP-seq
MIRT815970	hsa-miR-4779	CLIP-seq
MIRT815971	hsa-miR-490-3p	CLIP-seq
MIRT815972	hsa-miR-491-3p	CLIP-seq
MIRT815973	hsa-miR-506	CLIP-seq
MIRT815974	hsa-miR-520d-5p	CLIP-seq
MIRT815975	hsa-miR-524-5p	CLIP-seq
MIRT815976	hsa-miR-545	CLIP-seq
MIRT815977	hsa-miR-548an	CLIP-seq
MIRT815978	hsa-miR-590-5p	CLIP-seq
MIRT815979	hsa-miR-591	CLIP-seq
MIRT815980	hsa-miR-604	CLIP-seq
MIRT815981	hsa-miR-610	CLIP-seq
MIRT815982	hsa-miR-612	CLIP-seq
MIRT815983	hsa-miR-635	CLIP-seq
MIRT815984	hsa-miR-647	CLIP-seq
MIRT815985	hsa-miR-660	CLIP-seq
MIRT815986	hsa-miR-892b	CLIP-seq
MIRT1941347	hsa-miR-1207-3p	CLIP-seq
MIRT815927	hsa-miR-1273d	CLIP-seq
MIRT815929	hsa-miR-183	CLIP-seq
MIRT815930	hsa-miR-185	CLIP-seq
MIRT815935	hsa-miR-3064-5p	CLIP-seq
MIRT815936	hsa-miR-3127-5p	CLIP-seq
MIRT815937	hsa-miR-3146	CLIP-seq
MIRT815938	hsa-miR-3158-3p	CLIP-seq
MIRT815940	hsa-miR-33a	CLIP-seq
MIRT815941	hsa-miR-33b	CLIP-seq
MIRT1941348	hsa-miR-3689d	CLIP-seq
MIRT1941349	hsa-miR-376c	CLIP-seq
MIRT815949	hsa-miR-4257	CLIP-seq
MIRT815950	hsa-miR-4270	CLIP-seq
MIRT1941350	hsa-miR-4287	CLIP-seq
MIRT815952	hsa-miR-4306	CLIP-seq
MIRT1941351	hsa-miR-4307	CLIP-seq
MIRT815953	hsa-miR-4327	CLIP-seq
MIRT815954	hsa-miR-4419a	CLIP-seq
MIRT1941352	hsa-miR-4422	CLIP-seq
MIRT815955	hsa-miR-4433	CLIP-seq
MIRT815957	hsa-miR-4441	CLIP-seq
MIRT815958	hsa-miR-4446-3p	CLIP-seq
MIRT815959	hsa-miR-4459	CLIP-seq
MIRT1941353	hsa-miR-4469	CLIP-seq
MIRT815962	hsa-miR-4510	CLIP-seq
MIRT1941354	hsa-miR-4514	CLIP-seq
MIRT815964	hsa-miR-4633-5p	CLIP-seq
MIRT815965	hsa-miR-4644	CLIP-seq
MIRT1941355	hsa-miR-4685-3p	CLIP-seq
MIRT815966	hsa-miR-4686	CLIP-seq
MIRT1941356	hsa-miR-4692	CLIP-seq
MIRT815968	hsa-miR-4729	CLIP-seq
MIRT1941357	hsa-miR-4731-5p	CLIP-seq
MIRT815969	hsa-miR-4768-3p	CLIP-seq
MIRT815970	hsa-miR-4779	CLIP-seq
MIRT1941358	hsa-miR-486-3p	CLIP-seq
MIRT815972	hsa-miR-491-3p	CLIP-seq
MIRT1941359	hsa-miR-542-3p	CLIP-seq
MIRT1941360	hsa-miR-548c-3p	CLIP-seq
MIRT815980	hsa-miR-604	CLIP-seq
MIRT815981	hsa-miR-610	CLIP-seq
MIRT815984	hsa-miR-647	CLIP-seq
MIRT815985	hsa-miR-660	CLIP-seq
MIRT815986	hsa-miR-892b	CLIP-seq
MIRT815927	hsa-miR-1273d	CLIP-seq
MIRT815930	hsa-miR-185	CLIP-seq
MIRT815934	hsa-miR-217	CLIP-seq
MIRT815937	hsa-miR-3146	CLIP-seq
MIRT815943	hsa-miR-3692	CLIP-seq
MIRT2180121	hsa-miR-3974	CLIP-seq
MIRT815949	hsa-miR-4257	CLIP-seq
MIRT2180122	hsa-miR-4263	CLIP-seq
MIRT815952	hsa-miR-4306	CLIP-seq
MIRT815954	hsa-miR-4419a	CLIP-seq
MIRT815955	hsa-miR-4433	CLIP-seq
MIRT815956	hsa-miR-4436b-5p	CLIP-seq
MIRT815959	hsa-miR-4459	CLIP-seq
MIRT815962	hsa-miR-4510	CLIP-seq
MIRT815964	hsa-miR-4633-5p	CLIP-seq
MIRT815965	hsa-miR-4644	CLIP-seq
MIRT2180123	hsa-miR-4719	CLIP-seq
MIRT815968	hsa-miR-4729	CLIP-seq
MIRT815969	hsa-miR-4768-3p	CLIP-seq
MIRT815970	hsa-miR-4779	CLIP-seq
MIRT815972	hsa-miR-491-3p	CLIP-seq
MIRT2180124	hsa-miR-493	CLIP-seq
MIRT2180125	hsa-miR-494	CLIP-seq
MIRT2180126	hsa-miR-576-5p	CLIP-seq
MIRT815981	hsa-miR-610	CLIP-seq
MIRT815985	hsa-miR-660	CLIP-seq

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GO ID	Ontology	Definition	Evidence	Reference
GO:0000122	Process	Negative regulation of transcription by RNA polymerase II	IEA
GO:0000785	Component	Chromatin	ISA
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IBA
GO:0000977	Function	RNA polymerase II transcription regulatory region sequence-specific DNA binding	IMP	14744868
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IBA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	IEA
GO:0000981	Function	DNA-binding transcription factor activity, RNA polymerase II-specific	ISA
GO:0001228	Function	DNA-binding transcription activator activity, RNA polymerase II-specific	IMP	14744868
GO:0001502	Process	Cartilage condensation	IEA
GO:0003677	Function	DNA binding	IDA	10854790
GO:0003677	Function	DNA binding	IEA
GO:0003682	Function	Chromatin binding	IEA
GO:0003700	Function	DNA-binding transcription factor activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005667	Component	Transcription regulator complex	IEA
GO:0005794	Component	Golgi apparatus	IDA
GO:0005829	Component	Cytosol	IDA
GO:0006355	Process	Regulation of DNA-templated transcription	IEA
GO:0006357	Process	Regulation of transcription by RNA polymerase II	IBA
GO:0006366	Process	Transcription by RNA polymerase II	IEA
GO:0014902	Process	Myotube differentiation	IEA
GO:0015629	Component	Actin cytoskeleton	IDA
GO:0035914	Process	Skeletal muscle cell differentiation	IEA
GO:0043565	Function	Sequence-specific DNA binding	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IEA
GO:0045944	Process	Positive regulation of transcription by RNA polymerase II	IMP	14744868
GO:1990837	Function	Sequence-specific double-stranded DNA binding	IDA	28473536

MIM	HGNC	e!Ensembl
604823	956	ENSG00000043039

Q9UMQ3

Protein name

Homeobox protein BarH-like 2

Protein function

Transcription factor. Binds optimally to the DNA consensus sequence 5'-YYTAATGRTTTTY-3'. May control the expression of neural adhesion molecules such as L1 or Ng-CAM during embryonic development of both the central and peripherical nervous syste

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00046	Homeodomain	134 → 190	Homeodomain	Domain

Tissue specificity

TISSUE SPECIFICITY: Highly expressed in adult salivary gland and at much lower levels in mammary gland, kidney and placenta.

Sequence

MHCHAELRLSSPGQLKAARRRYKTFMIDEILSKETCDYFEKLSLYSVCPSLVVRPKPLHS
CTGSPSLRAYPLLSVITRQPTVISHLVPATPGIAQALSCHQVTEAVSAEAPGGEALASSE
SETEQPTPRQKKPRRSRTIFTELQLMGLEKKFQKQKYLSTPDRLDLAQSLGLTQLQVKTW
YQNRRMKWKKMVLKGGQEAPTKPKGRPKKNSIPTSEEIEAEEKMNSQAQGQEQLEPSQGQ
EELCEAQEPKARDVPLEMAEPPDPPQELPIPSSEPPPLS

Sequence length

279

Interactions

View interactions

BARX2 (BARX homeobox 2)