Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
85377
Gene name Gene Name - the full gene name approved by the HGNC.
MICAL like 1
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
MICALL1
Synonyms (NCBI Gene) Gene synonyms aliases
MICAL-L1, MIRAB13
Chromosome Chromosome number
22
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
22q13.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT025812 hsa-miR-7-5p Microarray 19073608
MIRT048743 hsa-miR-93-5p CLASH 23622248
MIRT042642 hsa-miR-423-3p CLASH 23622248
MIRT038075 hsa-miR-423-5p CLASH 23622248
MIRT035961 hsa-miR-1301-3p CLASH 23622248
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005515 Function Protein binding IPI 19864458, 19945174, 20801876, 21951725, 22284051, 23596323, 27189942
GO:0005769 Component Early endosome IDA 21795389
GO:0005770 Component Late endosome IDA 21795389
GO:0005802 Component Trans-Golgi network IDA 21795389
GO:0006612 Process Protein targeting to membrane IMP 19864458
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
619563 29804 ENSG00000100139
Protein
UniProt ID Q8N3F8
Protein name MICAL-like protein 1 (Molecule interacting with Rab13) (MIRab13)
Protein function Lipid-binding protein with higher affinity for phosphatidic acid, a lipid enriched in recycling endosome membranes. On endosome membranes, acts as a downstream effector of Rab proteins recruiting cytosolic proteins to regulate membrane tubulatio
PDB 2KSP
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00307 CH 2 109 Calponin homology (CH) domain Domain
PF00412 LIM 164 221 LIM domain Domain
PF12130 DUF3585 684 816 Bivalent Mical/EHBP Rab binding domain Domain
Sequence
MAGPRGALLAWCRRQCEGYRGVEIRDLSSSFRDGLAFCAILHRHRPDLLDFDSLSKDNVF
ENNRLAFEVAEKELGIPALLDPNDMVSMSVPDCLSIMTYVSQYYNHFCS
PGQAGVSPPRK
GLAPCSPPSVAPTPVEPEDVAQGEELSSGSLSEQGTGQTPSSTCAACQQHVHLVQRYLAD
GRLYHRHCFRCRRCSSTLLPGAYENGPEEGTFVCAEHCARL
GPGTRSGTRPGPFSQPKQQ
HQQQLAEDAKDVPGGGPSSSAPAGAEADGPKASPEARPQIPTKPRVPGKLQELASPPAGR
PTPAPRKASESTTPAPPTPRPRSSLQQENLVEQAGSSSLVNGRLHELPVPKPRGTPKPSE
GTPAPRKDPPWITLVQAEPKKKPAPLPPSSSPGPPSQDSRQVENGGTEEVAQPSPTASLE
SKPYNPFEEEEEDKEEEAPAAPSLATSPALGHPESTPKSLHPWYGITPTSSPKTKKRPAP
RAPSASPLALHASRLSHSEPPSATPSPALSVESLSSESASQTAGAELLEPPAVPKSSSEP
AVHAPGTPGNPVSLSTNSSLASSGELVEPRVEQMPQASPGLAPRTRGSSGPQPAKPCSGA
TPTPLLLVGDRSPVPSPGSSSPQLQVKSSCKENPFNRKPSPAASPATKKATKGSKPVRPP
APGHGFPLIKRKVQADQYIPEEDIHGEMDTIERRLDALEHRGVLLEEKLRGGLNEGREDD
MLVDWFKLIHEKHLLVRRESELIYVFKQQNLEQRQADVEYELRCLLNKPEKDWTEEDRAR
EKVLMQELVTLIEQRNAIINCLDEDRQREEEEDKML
EAMIKKKEFQREAEPEGKKKGKFK
TMKMLKLLGNKRDAKSKSPRDKS
Sequence length 863
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Breast cancer Malignant neoplasm of breast rs587776547, rs1137887, rs137853007, rs587776650, rs80359351, rs80359714, rs121917783, rs104886456, rs121964878, rs80359874, rs80357868, rs80357508, rs387906843, rs80357569, rs80358158
View all (309 more)
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 37248888
Inflammation Associate 37248888