Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
85315
Gene name Gene Name - the full gene name approved by the HGNC.
Progestin and adipoQ receptor family member 8
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PAQR8
Synonyms (NCBI Gene) Gene synonyms aliases
C6orf33, LMPB1, MPRB
Chromosome Chromosome number
6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
6p12.2
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT017929 hsa-miR-335-5p Microarray 18185580
MIRT019802 hsa-miR-375 Microarray 20215506
MIRT043654 hsa-miR-326 CLASH 23622248
MIRT655385 hsa-miR-5196-3p HITS-CLIP 23824327
MIRT655384 hsa-miR-361-3p HITS-CLIP 23824327
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0003707 Function Steroid hormone receptor activity IBA 21873635
GO:0005496 Function Steroid binding IBA 21873635
GO:0005515 Function Protein binding IPI 32296183
GO:0005794 Component Golgi apparatus IDA
GO:0005886 Component Plasma membrane IBA 21873635
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
607780 15708 ENSG00000170915
Protein
UniProt ID Q8TEZ7
Protein name Membrane progestin receptor beta (mPR beta) (Lysosomal membrane protein in brain 1) (Membrane progesterone P4 receptor beta) (Membrane progesterone receptor beta) (Progesterone and adipoQ receptor family member 8) (Progestin and adipoQ receptor family mem
Protein function Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (By similarity). Also binds dehydroepiandrosterone (DHEA), p
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03006 HlyIII 70 297 Haemolysin-III related Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed in the hypothalamus (PubMed:23161870). Also expressed in spinal cord, kidney and testis. {ECO:0000269|PubMed:11676489, ECO:0000269|PubMed:12601167, ECO:0000269|PubMed:16044242, ECO:0000269|PubMed:23161870}.
Sequence
Sequence length 354
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG  
  Chemical carcinogenesis - receptor activation  
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Unknown
Disease term Disease name Evidence References Source
Frontal Fibrosing Alopecia Frontal Fibrosing Alopecia GWAS
Associations from Text Mining
Disease Name Relationship Type References
Breast Neoplasms Associate 22350867
Calcinosis Cutis Associate 32657779
Carcinoma Hepatocellular Associate 35240821
Cerebral Infarction Associate 36582228
Endometrial Neoplasms Inhibit 32733932
Endometriosis Inhibit 32733932
Glioblastoma Associate 32077034
Inflammation Associate 36582228
Neoplasm Metastasis Associate 32657779
Prostatic Neoplasms Stimulate 34572596