Gene Gene information from NCBI Gene database.
Entrez ID 85315
Gene name Progestin and adipoQ receptor family member 8
Gene symbol PAQR8
Synonyms (NCBI Gene)
C6orf33LMPB1MPRB
Chromosome 6
Chromosome location 6p12.2
miRNA miRNA information provided by mirtarbase database.
333
miRTarBase ID miRNA Experiments Reference
MIRT017929 hsa-miR-335-5p Microarray 18185580
MIRT019802 hsa-miR-375 Microarray 20215506
MIRT043654 hsa-miR-326 CLASH 23622248
MIRT655385 hsa-miR-5196-3p HITS-CLIP 23824327
MIRT655384 hsa-miR-361-3p HITS-CLIP 23824327
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14
GO ID Ontology Definition Evidence Reference
GO:0003707 Function Nuclear steroid receptor activity IBA
GO:0005496 Function Steroid binding IBA
GO:0005496 Function Steroid binding IEA
GO:0005515 Function Protein binding IPI 32296183
GO:0005794 Component Golgi apparatus IDA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
607780 15708 ENSG00000170915
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q8TEZ7
Protein name Membrane progestin receptor beta (mPR beta) (Lysosomal membrane protein in brain 1) (Membrane progesterone P4 receptor beta) (Membrane progesterone receptor beta) (Progesterone and adipoQ receptor family member 8) (Progestin and adipoQ receptor family mem
Protein function Plasma membrane progesterone (P4) receptor coupled to G proteins (PubMed:23763432). Seems to act through a G(i) mediated pathway (PubMed:23763432). May be involved in oocyte maturation (By similarity). Also binds dehydroepiandrosterone (DHEA), p
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF03006 HlyIII 70 297 Haemolysin-III related Family
Tissue specificity TISSUE SPECIFICITY: Highly expressed in the hypothalamus (PubMed:23161870). Also expressed in spinal cord, kidney and testis. {ECO:0000269|PubMed:11676489, ECO:0000269|PubMed:12601167, ECO:0000269|PubMed:16044242, ECO:0000269|PubMed:23161870}.
Sequence
Sequence length 354
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG 
  Chemical carcinogenesis - receptor activation