Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	85313
Gene name Gene Name - the full gene name approved by the HGNC.	Peptidylprolyl isomerase like 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PPIL4
Synonyms (NCBI Gene) Gene synonyms aliases	HDCME13P
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6q25.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. [

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miRTarBase ID	miRNA	Experiments	Reference
MIRT044617	hsa-miR-320a	CLASH	23622248
MIRT037278	hsa-miR-877-5p	CLASH	23622248
MIRT666860	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT694028	hsa-miR-4695-5p	HITS-CLIP	23313552
MIRT694027	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT694026	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT694025	hsa-miR-652-3p	HITS-CLIP	23313552
MIRT694024	hsa-miR-4459	HITS-CLIP	23313552
MIRT694023	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT694022	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT694021	hsa-miR-6840-3p	HITS-CLIP	23313552
MIRT694020	hsa-miR-939-3p	HITS-CLIP	23313552
MIRT694019	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT694018	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT694017	hsa-miR-17-3p	HITS-CLIP	23313552
MIRT694016	hsa-miR-1285-3p	HITS-CLIP	23313552
MIRT694015	hsa-miR-3187-5p	HITS-CLIP	23313552
MIRT694014	hsa-miR-5189-5p	HITS-CLIP	23313552
MIRT694013	hsa-miR-612	HITS-CLIP	23313552
MIRT694012	hsa-miR-6860	HITS-CLIP	23313552
MIRT694011	hsa-miR-143-3p	HITS-CLIP	23313552
MIRT694010	hsa-miR-4770	HITS-CLIP	23313552
MIRT694009	hsa-miR-6088	HITS-CLIP	23313552
MIRT694008	hsa-miR-4708-5p	HITS-CLIP	23313552
MIRT694007	hsa-miR-1273f	HITS-CLIP	23313552
MIRT694006	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT694005	hsa-miR-558	HITS-CLIP	23313552
MIRT694004	hsa-miR-4487	HITS-CLIP	23313552
MIRT694003	hsa-miR-1827	HITS-CLIP	23313552
MIRT694002	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT694001	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT666859	hsa-miR-891a-5p	HITS-CLIP	23313552
MIRT694000	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT693999	hsa-miR-6499-3p	HITS-CLIP	23313552
MIRT693998	hsa-miR-4252	HITS-CLIP	23313552
MIRT693997	hsa-miR-661	HITS-CLIP	23313552
MIRT693996	hsa-miR-3612	HITS-CLIP	23313552
MIRT693995	hsa-miR-650	HITS-CLIP	23313552
MIRT693994	hsa-miR-6789-3p	HITS-CLIP	23313552
MIRT693993	hsa-miR-566	HITS-CLIP	23313552
MIRT693992	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT693991	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT693990	hsa-miR-7703	HITS-CLIP	23313552
MIRT666860	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT666859	hsa-miR-891a-5p	HITS-CLIP	23824327
MIRT504393	hsa-miR-548e-5p	PAR-CLIP	21572407
MIRT504392	hsa-miR-3662	PAR-CLIP	21572407
MIRT504391	hsa-miR-3913-3p	PAR-CLIP	21572407
MIRT504390	hsa-miR-3148	PAR-CLIP	21572407
MIRT504389	hsa-miR-489-3p	PAR-CLIP	21572407
MIRT504393	hsa-miR-548e-5p	PAR-CLIP	23446348
MIRT504392	hsa-miR-3662	PAR-CLIP	23446348
MIRT504391	hsa-miR-3913-3p	PAR-CLIP	23446348
MIRT504390	hsa-miR-3148	PAR-CLIP	23446348
MIRT504389	hsa-miR-489-3p	PAR-CLIP	23446348
MIRT492597	hsa-miR-381-3p	PAR-CLIP	23592263
MIRT492596	hsa-miR-300	PAR-CLIP	23592263
MIRT492595	hsa-miR-548n	PAR-CLIP	23592263
MIRT492594	hsa-miR-4282	PAR-CLIP	23592263
MIRT492593	hsa-miR-548l	PAR-CLIP	23592263
MIRT492592	hsa-miR-4280	PAR-CLIP	23592263
MIRT492591	hsa-miR-3163	PAR-CLIP	23592263
MIRT492590	hsa-miR-4666a-3p	PAR-CLIP	23592263
MIRT492589	hsa-miR-95-5p	PAR-CLIP	23592263
MIRT492588	hsa-miR-520d-5p	PAR-CLIP	23592263
MIRT492587	hsa-miR-524-5p	PAR-CLIP	23592263
MIRT492586	hsa-miR-142-3p	PAR-CLIP	23592263
MIRT098814	hsa-let-7a-3p	PAR-CLIP	23592263
MIRT098815	hsa-let-7b-3p	PAR-CLIP	23592263
MIRT098816	hsa-let-7f-1-3p	PAR-CLIP	23592263
MIRT098818	hsa-miR-98-3p	PAR-CLIP	23592263
MIRT492585	hsa-miR-3591-5p	PAR-CLIP	23592263
MIRT694023	hsa-miR-1273g-3p	PAR-CLIP	27292025
MIRT693998	hsa-miR-4252	PAR-CLIP	27292025
MIRT694018	hsa-miR-4793-3p	PAR-CLIP	27292025
MIRT666860	hsa-miR-508-5p	PAR-CLIP	27292025
MIRT693992	hsa-miR-6512-3p	PAR-CLIP	27292025
MIRT693997	hsa-miR-661	PAR-CLIP	27292025
MIRT693991	hsa-miR-6720-5p	PAR-CLIP	27292025
MIRT694022	hsa-miR-6849-3p	PAR-CLIP	27292025
MIRT694019	hsa-miR-766-3p	PAR-CLIP	27292025
MIRT693990	hsa-miR-7703	PAR-CLIP	27292025
MIRT666860	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT694028	hsa-miR-4695-5p	HITS-CLIP	23313552
MIRT694027	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT694026	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT694025	hsa-miR-652-3p	HITS-CLIP	23313552
MIRT694024	hsa-miR-4459	HITS-CLIP	23313552
MIRT694023	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT694022	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT694021	hsa-miR-6840-3p	HITS-CLIP	23313552
MIRT694020	hsa-miR-939-3p	HITS-CLIP	23313552
MIRT694019	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT694018	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT694017	hsa-miR-17-3p	HITS-CLIP	23313552
MIRT694016	hsa-miR-1285-3p	HITS-CLIP	23313552
MIRT694015	hsa-miR-3187-5p	HITS-CLIP	23313552
MIRT694014	hsa-miR-5189-5p	HITS-CLIP	23313552
MIRT694013	hsa-miR-612	HITS-CLIP	23313552
MIRT694012	hsa-miR-6860	HITS-CLIP	23313552
MIRT694011	hsa-miR-143-3p	HITS-CLIP	23313552
MIRT694010	hsa-miR-4770	HITS-CLIP	23313552
MIRT694009	hsa-miR-6088	HITS-CLIP	23313552
MIRT694008	hsa-miR-4708-5p	HITS-CLIP	23313552
MIRT694007	hsa-miR-1273f	HITS-CLIP	23313552
MIRT694006	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT694005	hsa-miR-558	HITS-CLIP	23313552
MIRT694004	hsa-miR-4487	HITS-CLIP	23313552
MIRT694003	hsa-miR-1827	HITS-CLIP	23313552
MIRT694002	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT694001	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT666859	hsa-miR-891a-5p	HITS-CLIP	23313552
MIRT694000	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT693999	hsa-miR-6499-3p	HITS-CLIP	23313552
MIRT693998	hsa-miR-4252	HITS-CLIP	23313552
MIRT693997	hsa-miR-661	HITS-CLIP	23313552
MIRT693996	hsa-miR-3612	HITS-CLIP	23313552
MIRT693995	hsa-miR-650	HITS-CLIP	23313552
MIRT693994	hsa-miR-6789-3p	HITS-CLIP	23313552
MIRT693993	hsa-miR-566	HITS-CLIP	23313552
MIRT693992	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT693991	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT693990	hsa-miR-7703	HITS-CLIP	23313552
MIRT666860	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT666859	hsa-miR-891a-5p	HITS-CLIP	23824327
MIRT504393	hsa-miR-548e-5p	PAR-CLIP	21572407
MIRT504392	hsa-miR-3662	PAR-CLIP	21572407
MIRT504391	hsa-miR-3913-3p	PAR-CLIP	21572407
MIRT504390	hsa-miR-3148	PAR-CLIP	21572407
MIRT504389	hsa-miR-489-3p	PAR-CLIP	21572407
MIRT504393	hsa-miR-548e-5p	PAR-CLIP	23446348
MIRT504392	hsa-miR-3662	PAR-CLIP	23446348
MIRT504391	hsa-miR-3913-3p	PAR-CLIP	23446348
MIRT504390	hsa-miR-3148	PAR-CLIP	23446348
MIRT504389	hsa-miR-489-3p	PAR-CLIP	23446348
MIRT492597	hsa-miR-381-3p	PAR-CLIP	23592263
MIRT492596	hsa-miR-300	PAR-CLIP	23592263
MIRT492595	hsa-miR-548n	PAR-CLIP	23592263
MIRT492594	hsa-miR-4282	PAR-CLIP	23592263
MIRT492593	hsa-miR-548l	PAR-CLIP	23592263
MIRT492592	hsa-miR-4280	PAR-CLIP	23592263
MIRT492591	hsa-miR-3163	PAR-CLIP	23592263
MIRT492590	hsa-miR-4666a-3p	PAR-CLIP	23592263
MIRT492589	hsa-miR-95-5p	PAR-CLIP	23592263
MIRT492588	hsa-miR-520d-5p	PAR-CLIP	23592263
MIRT492587	hsa-miR-524-5p	PAR-CLIP	23592263
MIRT492586	hsa-miR-142-3p	PAR-CLIP	23592263
MIRT098814	hsa-let-7a-3p	PAR-CLIP	23592263
MIRT098815	hsa-let-7b-3p	PAR-CLIP	23592263
MIRT098816	hsa-let-7f-1-3p	PAR-CLIP	23592263
MIRT098818	hsa-miR-98-3p	PAR-CLIP	23592263
MIRT492585	hsa-miR-3591-5p	PAR-CLIP	23592263
MIRT1253267	hsa-miR-103a	CLIP-seq
MIRT1253268	hsa-miR-105	CLIP-seq
MIRT1253269	hsa-miR-107	CLIP-seq
MIRT1253270	hsa-miR-1256	CLIP-seq
MIRT1253271	hsa-miR-1271	CLIP-seq
MIRT1253272	hsa-miR-1305	CLIP-seq
MIRT1253273	hsa-miR-15a	CLIP-seq
MIRT1253274	hsa-miR-15b	CLIP-seq
MIRT1253275	hsa-miR-16	CLIP-seq
MIRT1253276	hsa-miR-182	CLIP-seq
MIRT1253277	hsa-miR-188-5p	CLIP-seq
MIRT1253278	hsa-miR-1911	CLIP-seq
MIRT1253279	hsa-miR-195	CLIP-seq
MIRT1253280	hsa-miR-202	CLIP-seq
MIRT1253281	hsa-miR-204	CLIP-seq
MIRT1253282	hsa-miR-211	CLIP-seq
MIRT1253283	hsa-miR-224	CLIP-seq
MIRT1253284	hsa-miR-27a	CLIP-seq
MIRT1253285	hsa-miR-27b	CLIP-seq
MIRT1253286	hsa-miR-3064-5p	CLIP-seq
MIRT1253287	hsa-miR-3074-3p	CLIP-seq
MIRT1253288	hsa-miR-30a	CLIP-seq
MIRT1253289	hsa-miR-30b	CLIP-seq
MIRT1253290	hsa-miR-30c	CLIP-seq
MIRT1253291	hsa-miR-30d	CLIP-seq
MIRT1253292	hsa-miR-30e	CLIP-seq
MIRT1253293	hsa-miR-3120-3p	CLIP-seq
MIRT1253294	hsa-miR-3143	CLIP-seq
MIRT1253295	hsa-miR-3145-3p	CLIP-seq
MIRT1253296	hsa-miR-320e	CLIP-seq
MIRT1253297	hsa-miR-3646	CLIP-seq
MIRT1253298	hsa-miR-3674	CLIP-seq
MIRT1253299	hsa-miR-382	CLIP-seq
MIRT1253300	hsa-miR-3923	CLIP-seq
MIRT1253301	hsa-miR-3924	CLIP-seq
MIRT1253302	hsa-miR-3942-5p	CLIP-seq
MIRT1253303	hsa-miR-410	CLIP-seq
MIRT1253304	hsa-miR-421	CLIP-seq
MIRT1253305	hsa-miR-424	CLIP-seq
MIRT1253306	hsa-miR-4310	CLIP-seq
MIRT1253307	hsa-miR-4502	CLIP-seq
MIRT1253308	hsa-miR-4509	CLIP-seq
MIRT1253309	hsa-miR-4642	CLIP-seq
MIRT1253310	hsa-miR-4659a-5p	CLIP-seq
MIRT1253311	hsa-miR-4659b-5p	CLIP-seq
MIRT1253312	hsa-miR-4666-3p	CLIP-seq
MIRT1253313	hsa-miR-4672	CLIP-seq
MIRT1253314	hsa-miR-4699-3p	CLIP-seq
MIRT1253315	hsa-miR-4703-5p	CLIP-seq
MIRT1253316	hsa-miR-4704-3p	CLIP-seq
MIRT1253317	hsa-miR-4709-5p	CLIP-seq
MIRT1253318	hsa-miR-4719	CLIP-seq
MIRT1253319	hsa-miR-4729	CLIP-seq
MIRT1253320	hsa-miR-4742-3p	CLIP-seq
MIRT1253321	hsa-miR-4744	CLIP-seq
MIRT1253322	hsa-miR-4776-3p	CLIP-seq
MIRT1253323	hsa-miR-4795-3p	CLIP-seq
MIRT1253324	hsa-miR-497	CLIP-seq
MIRT1253325	hsa-miR-500a	CLIP-seq
MIRT1253326	hsa-miR-513a-5p	CLIP-seq
MIRT1253327	hsa-miR-543	CLIP-seq
MIRT1253328	hsa-miR-545	CLIP-seq
MIRT1253329	hsa-miR-548p	CLIP-seq
MIRT1253330	hsa-miR-548u	CLIP-seq
MIRT1253331	hsa-miR-600	CLIP-seq
MIRT1253332	hsa-miR-96	CLIP-seq
MIRT1253267	hsa-miR-103a	CLIP-seq
MIRT1253269	hsa-miR-107	CLIP-seq
MIRT1253270	hsa-miR-1256	CLIP-seq
MIRT1253271	hsa-miR-1271	CLIP-seq
MIRT2301553	hsa-miR-128	CLIP-seq
MIRT1253272	hsa-miR-1305	CLIP-seq
MIRT2301554	hsa-miR-1343	CLIP-seq
MIRT1253273	hsa-miR-15a	CLIP-seq
MIRT1253274	hsa-miR-15b	CLIP-seq
MIRT1253275	hsa-miR-16	CLIP-seq
MIRT1253276	hsa-miR-182	CLIP-seq
MIRT1253279	hsa-miR-195	CLIP-seq
MIRT1253280	hsa-miR-202	CLIP-seq
MIRT1253283	hsa-miR-224	CLIP-seq
MIRT1253284	hsa-miR-27a	CLIP-seq
MIRT1253285	hsa-miR-27b	CLIP-seq
MIRT2301555	hsa-miR-3074-5p	CLIP-seq
MIRT1253288	hsa-miR-30a	CLIP-seq
MIRT1253289	hsa-miR-30b	CLIP-seq
MIRT1253290	hsa-miR-30c	CLIP-seq
MIRT1253291	hsa-miR-30d	CLIP-seq
MIRT1253292	hsa-miR-30e	CLIP-seq
MIRT2301556	hsa-miR-3124-3p	CLIP-seq
MIRT1253294	hsa-miR-3143	CLIP-seq
MIRT2301557	hsa-miR-3160-5p	CLIP-seq
MIRT2301558	hsa-miR-3613-3p	CLIP-seq
MIRT1253297	hsa-miR-3646	CLIP-seq
MIRT1253300	hsa-miR-3923	CLIP-seq
MIRT1253301	hsa-miR-3924	CLIP-seq
MIRT2301559	hsa-miR-3941	CLIP-seq
MIRT1253303	hsa-miR-410	CLIP-seq
MIRT1253304	hsa-miR-421	CLIP-seq
MIRT1253305	hsa-miR-424	CLIP-seq
MIRT1253306	hsa-miR-4310	CLIP-seq
MIRT2301560	hsa-miR-4480	CLIP-seq
MIRT1253309	hsa-miR-4642	CLIP-seq
MIRT2301561	hsa-miR-4643	CLIP-seq
MIRT1253310	hsa-miR-4659a-5p	CLIP-seq
MIRT1253311	hsa-miR-4659b-5p	CLIP-seq
MIRT2301562	hsa-miR-466	CLIP-seq
MIRT1253312	hsa-miR-4666-3p	CLIP-seq
MIRT1253313	hsa-miR-4672	CLIP-seq
MIRT2301563	hsa-miR-4686	CLIP-seq
MIRT1253316	hsa-miR-4704-3p	CLIP-seq
MIRT1253317	hsa-miR-4709-5p	CLIP-seq
MIRT1253318	hsa-miR-4719	CLIP-seq
MIRT1253319	hsa-miR-4729	CLIP-seq
MIRT1253322	hsa-miR-4776-3p	CLIP-seq
MIRT2301564	hsa-miR-4789-3p	CLIP-seq
MIRT2301565	hsa-miR-489	CLIP-seq
MIRT1253324	hsa-miR-497	CLIP-seq
MIRT1253326	hsa-miR-513a-5p	CLIP-seq
MIRT2301566	hsa-miR-568	CLIP-seq
MIRT1253331	hsa-miR-600	CLIP-seq
MIRT1253332	hsa-miR-96	CLIP-seq
MIRT2301554	hsa-miR-1343	CLIP-seq
MIRT1253277	hsa-miR-188-5p	CLIP-seq
MIRT1253278	hsa-miR-1911	CLIP-seq
MIRT1253281	hsa-miR-204	CLIP-seq
MIRT1253282	hsa-miR-211	CLIP-seq
MIRT1253286	hsa-miR-3064-5p	CLIP-seq
MIRT2301555	hsa-miR-3074-5p	CLIP-seq
MIRT2301556	hsa-miR-3124-3p	CLIP-seq
MIRT1253295	hsa-miR-3145-3p	CLIP-seq
MIRT2301557	hsa-miR-3160-5p	CLIP-seq
MIRT2598248	hsa-miR-3162-5p	CLIP-seq
MIRT1253296	hsa-miR-320e	CLIP-seq
MIRT2598249	hsa-miR-4419a	CLIP-seq
MIRT2598250	hsa-miR-4471	CLIP-seq
MIRT1253307	hsa-miR-4502	CLIP-seq
MIRT2598251	hsa-miR-4510	CLIP-seq
MIRT2598252	hsa-miR-4512	CLIP-seq
MIRT1253313	hsa-miR-4672	CLIP-seq
MIRT2301563	hsa-miR-4686	CLIP-seq
MIRT1253314	hsa-miR-4699-3p	CLIP-seq
MIRT1253319	hsa-miR-4729	CLIP-seq
MIRT1253320	hsa-miR-4742-3p	CLIP-seq
MIRT1253323	hsa-miR-4795-3p	CLIP-seq
MIRT2598253	hsa-miR-4799-5p	CLIP-seq
MIRT2598254	hsa-miR-642b	CLIP-seq
MIRT2598255	hsa-miR-944	CLIP-seq
MIRT2301554	hsa-miR-1343	CLIP-seq
MIRT1253277	hsa-miR-188-5p	CLIP-seq
MIRT1253278	hsa-miR-1911	CLIP-seq
MIRT1253281	hsa-miR-204	CLIP-seq
MIRT1253282	hsa-miR-211	CLIP-seq
MIRT1253286	hsa-miR-3064-5p	CLIP-seq
MIRT2301555	hsa-miR-3074-5p	CLIP-seq
MIRT2301556	hsa-miR-3124-3p	CLIP-seq
MIRT1253295	hsa-miR-3145-3p	CLIP-seq
MIRT2301557	hsa-miR-3160-5p	CLIP-seq
MIRT2598248	hsa-miR-3162-5p	CLIP-seq
MIRT1253296	hsa-miR-320e	CLIP-seq
MIRT2598249	hsa-miR-4419a	CLIP-seq
MIRT2598250	hsa-miR-4471	CLIP-seq
MIRT1253307	hsa-miR-4502	CLIP-seq
MIRT2598251	hsa-miR-4510	CLIP-seq
MIRT2598252	hsa-miR-4512	CLIP-seq
MIRT1253313	hsa-miR-4672	CLIP-seq
MIRT2301563	hsa-miR-4686	CLIP-seq
MIRT1253314	hsa-miR-4699-3p	CLIP-seq
MIRT1253319	hsa-miR-4729	CLIP-seq
MIRT1253320	hsa-miR-4742-3p	CLIP-seq
MIRT1253323	hsa-miR-4795-3p	CLIP-seq
MIRT2598253	hsa-miR-4799-5p	CLIP-seq
MIRT2598254	hsa-miR-642b	CLIP-seq
MIRT2598255	hsa-miR-944	CLIP-seq

Show/Hide all(11)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003723	Function	RNA binding	IEA
GO:0003755	Function	Peptidyl-prolyl cis-trans isomerase activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005654	Component	Nucleoplasm	IDA
GO:0005654	Component	Nucleoplasm	TAS
GO:0005829	Component	Cytosol	IDA
GO:0016853	Function	Isomerase activity	IEA

MIM	HGNC	e!Ensembl
607609	15702	ENSG00000131013

Protein

UniProt ID

Q8WUA2

Protein name

Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4)

Protein function

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

PDB

7QTT , 8CH6 , 8I0S , 8I0T , 8I0U , 8I0V

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00160	Pro_isomerase	2 → 161	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	Domain
PF00076	RRM_1	242 → 312	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain

Tissue specificity

TISSUE SPECIFICITY: Abundantly expressed in kidney but has a ubiquitously low expression pattern in other adult tissues. {ECO:0000269|PubMed:11978968}.

Sequence

MAVLLETTLGDVVIDLYTEERPRACLNFLKLCKIKYYNYCLIHNVQRDFIIQTGDPTGTG
RGGESIFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDYLD
GVHTVFGEVTEGMDIIKKINETFVDKDFVPYQDIRINHTVILDDPFDDPPDLLIPDRSPE
PTREQLDSGRIGADEEIDDFKGRSAEEVEEIKAEKEAKTQAILLEMVGDLPDADIKPPEN
VLFVCKLNPVTTDEDLEIIFSRFGPIRSCEVIRDWKTGESLCYAFIEFEKEEDCEKAFFK
MDNVLIDDRRIHVDFSQSVAKVKWKGKGGKYTKSDFKEYEKEQDKPPNLVLKDKVKPKQD
TKYDLILDEQAEDSKSSHSHTSKKHKKKTHHCSEEKEDEDYMPIKNTNQDIYREMGFGHY
EEEESCWEKQKSEKRDRTQNRSRSRSRERDGHYSNSHKSKYQTDLYERERSKKRDRSRSP
KKSKDKEKSKYR

Sequence length

492

Interactions

View interactions

	Reactome
			mRNA Splicing - Major Pathway

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Glioblastoma	Glioblastoma	N/A	N/A	GWAS
Rheumatoid arthritis	Rheumatoid arthritis	N/A	N/A	GWAS

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Cerebral Hemorrhage	Associate	34887573
Intracranial Aneurysm	Associate	34887573

PPIL4 (peptidylprolyl isomerase like 4)