Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	85313
Gene name Gene Name - the full gene name approved by the HGNC.	Peptidylprolyl isomerase like 4
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	PPIL4
Synonyms (NCBI Gene) Gene synonyms aliases	HDCME13P
Chromosome Chromosome number	6
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	6q25.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene is a member of the cyclophilin family of peptidylprolyl isomerases. The cyclophilins are a highly conserved family, members of which play an important role in protein folding, immunosuppression by cyclosporin A, and infection of HIV-1 virions. [

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miRTarBase ID	miRNA	Experiments	Reference
MIRT044617	hsa-miR-320a	CLASH	23622248
MIRT037278	hsa-miR-877-5p	CLASH	23622248
MIRT666860	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT694028	hsa-miR-4695-5p	HITS-CLIP	23313552
MIRT694027	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT694026	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT694025	hsa-miR-652-3p	HITS-CLIP	23313552
MIRT694024	hsa-miR-4459	HITS-CLIP	23313552
MIRT694023	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT694022	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT694021	hsa-miR-6840-3p	HITS-CLIP	23313552
MIRT694020	hsa-miR-939-3p	HITS-CLIP	23313552
MIRT694019	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT694018	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT694017	hsa-miR-17-3p	HITS-CLIP	23313552
MIRT694016	hsa-miR-1285-3p	HITS-CLIP	23313552
MIRT694015	hsa-miR-3187-5p	HITS-CLIP	23313552
MIRT694014	hsa-miR-5189-5p	HITS-CLIP	23313552
MIRT694013	hsa-miR-612	HITS-CLIP	23313552
MIRT694012	hsa-miR-6860	HITS-CLIP	23313552
MIRT694011	hsa-miR-143-3p	HITS-CLIP	23313552
MIRT694010	hsa-miR-4770	HITS-CLIP	23313552
MIRT694009	hsa-miR-6088	HITS-CLIP	23313552
MIRT694008	hsa-miR-4708-5p	HITS-CLIP	23313552
MIRT694007	hsa-miR-1273f	HITS-CLIP	23313552
MIRT694006	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT694005	hsa-miR-558	HITS-CLIP	23313552
MIRT694004	hsa-miR-4487	HITS-CLIP	23313552
MIRT694003	hsa-miR-1827	HITS-CLIP	23313552
MIRT694002	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT694001	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT666859	hsa-miR-891a-5p	HITS-CLIP	23313552
MIRT694000	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT693999	hsa-miR-6499-3p	HITS-CLIP	23313552
MIRT693998	hsa-miR-4252	HITS-CLIP	23313552
MIRT693997	hsa-miR-661	HITS-CLIP	23313552
MIRT693996	hsa-miR-3612	HITS-CLIP	23313552
MIRT693995	hsa-miR-650	HITS-CLIP	23313552
MIRT693994	hsa-miR-6789-3p	HITS-CLIP	23313552
MIRT693993	hsa-miR-566	HITS-CLIP	23313552
MIRT693992	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT693991	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT693990	hsa-miR-7703	HITS-CLIP	23313552
MIRT666860	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT666859	hsa-miR-891a-5p	HITS-CLIP	23824327
MIRT504393	hsa-miR-548e-5p	PAR-CLIP	21572407
MIRT504392	hsa-miR-3662	PAR-CLIP	21572407
MIRT504391	hsa-miR-3913-3p	PAR-CLIP	21572407
MIRT504390	hsa-miR-3148	PAR-CLIP	21572407
MIRT504389	hsa-miR-489-3p	PAR-CLIP	21572407
MIRT504393	hsa-miR-548e-5p	PAR-CLIP	23446348
MIRT504392	hsa-miR-3662	PAR-CLIP	23446348
MIRT504391	hsa-miR-3913-3p	PAR-CLIP	23446348
MIRT504390	hsa-miR-3148	PAR-CLIP	23446348
MIRT504389	hsa-miR-489-3p	PAR-CLIP	23446348
MIRT492597	hsa-miR-381-3p	PAR-CLIP	23592263
MIRT492596	hsa-miR-300	PAR-CLIP	23592263
MIRT492595	hsa-miR-548n	PAR-CLIP	23592263
MIRT492594	hsa-miR-4282	PAR-CLIP	23592263
MIRT492593	hsa-miR-548l	PAR-CLIP	23592263
MIRT492592	hsa-miR-4280	PAR-CLIP	23592263
MIRT492591	hsa-miR-3163	PAR-CLIP	23592263
MIRT492590	hsa-miR-4666a-3p	PAR-CLIP	23592263
MIRT492589	hsa-miR-95-5p	PAR-CLIP	23592263
MIRT492588	hsa-miR-520d-5p	PAR-CLIP	23592263
MIRT492587	hsa-miR-524-5p	PAR-CLIP	23592263
MIRT492586	hsa-miR-142-3p	PAR-CLIP	23592263
MIRT098814	hsa-let-7a-3p	PAR-CLIP	23592263
MIRT098815	hsa-let-7b-3p	PAR-CLIP	23592263
MIRT098816	hsa-let-7f-1-3p	PAR-CLIP	23592263
MIRT098818	hsa-miR-98-3p	PAR-CLIP	23592263
MIRT492585	hsa-miR-3591-5p	PAR-CLIP	23592263
MIRT694023	hsa-miR-1273g-3p	PAR-CLIP	27292025
MIRT693998	hsa-miR-4252	PAR-CLIP	27292025
MIRT694018	hsa-miR-4793-3p	PAR-CLIP	27292025
MIRT666860	hsa-miR-508-5p	PAR-CLIP	27292025
MIRT693992	hsa-miR-6512-3p	PAR-CLIP	27292025
MIRT693997	hsa-miR-661	PAR-CLIP	27292025
MIRT693991	hsa-miR-6720-5p	PAR-CLIP	27292025
MIRT694022	hsa-miR-6849-3p	PAR-CLIP	27292025
MIRT694019	hsa-miR-766-3p	PAR-CLIP	27292025
MIRT693990	hsa-miR-7703	PAR-CLIP	27292025
MIRT666860	hsa-miR-508-5p	HITS-CLIP	23313552
MIRT694028	hsa-miR-4695-5p	HITS-CLIP	23313552
MIRT694027	hsa-miR-1910-3p	HITS-CLIP	23313552
MIRT694026	hsa-miR-6511a-5p	HITS-CLIP	23313552
MIRT694025	hsa-miR-652-3p	HITS-CLIP	23313552
MIRT694024	hsa-miR-4459	HITS-CLIP	23313552
MIRT694023	hsa-miR-1273g-3p	HITS-CLIP	23313552
MIRT694022	hsa-miR-6849-3p	HITS-CLIP	23313552
MIRT694021	hsa-miR-6840-3p	HITS-CLIP	23313552
MIRT694020	hsa-miR-939-3p	HITS-CLIP	23313552
MIRT694019	hsa-miR-766-3p	HITS-CLIP	23313552
MIRT694018	hsa-miR-4793-3p	HITS-CLIP	23313552
MIRT694017	hsa-miR-17-3p	HITS-CLIP	23313552
MIRT694016	hsa-miR-1285-3p	HITS-CLIP	23313552
MIRT694015	hsa-miR-3187-5p	HITS-CLIP	23313552
MIRT694014	hsa-miR-5189-5p	HITS-CLIP	23313552
MIRT694013	hsa-miR-612	HITS-CLIP	23313552
MIRT694012	hsa-miR-6860	HITS-CLIP	23313552
MIRT694011	hsa-miR-143-3p	HITS-CLIP	23313552
MIRT694010	hsa-miR-4770	HITS-CLIP	23313552
MIRT694009	hsa-miR-6088	HITS-CLIP	23313552
MIRT694008	hsa-miR-4708-5p	HITS-CLIP	23313552
MIRT694007	hsa-miR-1273f	HITS-CLIP	23313552
MIRT694006	hsa-miR-3160-3p	HITS-CLIP	23313552
MIRT694005	hsa-miR-558	HITS-CLIP	23313552
MIRT694004	hsa-miR-4487	HITS-CLIP	23313552
MIRT694003	hsa-miR-1827	HITS-CLIP	23313552
MIRT694002	hsa-miR-485-5p	HITS-CLIP	23313552
MIRT694001	hsa-miR-6884-5p	HITS-CLIP	23313552
MIRT666859	hsa-miR-891a-5p	HITS-CLIP	23313552
MIRT694000	hsa-miR-2467-3p	HITS-CLIP	23313552
MIRT693999	hsa-miR-6499-3p	HITS-CLIP	23313552
MIRT693998	hsa-miR-4252	HITS-CLIP	23313552
MIRT693997	hsa-miR-661	HITS-CLIP	23313552
MIRT693996	hsa-miR-3612	HITS-CLIP	23313552
MIRT693995	hsa-miR-650	HITS-CLIP	23313552
MIRT693994	hsa-miR-6789-3p	HITS-CLIP	23313552
MIRT693993	hsa-miR-566	HITS-CLIP	23313552
MIRT693992	hsa-miR-6512-3p	HITS-CLIP	23313552
MIRT693991	hsa-miR-6720-5p	HITS-CLIP	23313552
MIRT693990	hsa-miR-7703	HITS-CLIP	23313552
MIRT666860	hsa-miR-508-5p	HITS-CLIP	23824327
MIRT666859	hsa-miR-891a-5p	HITS-CLIP	23824327
MIRT504393	hsa-miR-548e-5p	PAR-CLIP	21572407
MIRT504392	hsa-miR-3662	PAR-CLIP	21572407
MIRT504391	hsa-miR-3913-3p	PAR-CLIP	21572407
MIRT504390	hsa-miR-3148	PAR-CLIP	21572407
MIRT504389	hsa-miR-489-3p	PAR-CLIP	21572407
MIRT504393	hsa-miR-548e-5p	PAR-CLIP	23446348
MIRT504392	hsa-miR-3662	PAR-CLIP	23446348
MIRT504391	hsa-miR-3913-3p	PAR-CLIP	23446348
MIRT504390	hsa-miR-3148	PAR-CLIP	23446348
MIRT504389	hsa-miR-489-3p	PAR-CLIP	23446348
MIRT492597	hsa-miR-381-3p	PAR-CLIP	23592263
MIRT492596	hsa-miR-300	PAR-CLIP	23592263
MIRT492595	hsa-miR-548n	PAR-CLIP	23592263
MIRT492594	hsa-miR-4282	PAR-CLIP	23592263
MIRT492593	hsa-miR-548l	PAR-CLIP	23592263
MIRT492592	hsa-miR-4280	PAR-CLIP	23592263
MIRT492591	hsa-miR-3163	PAR-CLIP	23592263
MIRT492590	hsa-miR-4666a-3p	PAR-CLIP	23592263
MIRT492589	hsa-miR-95-5p	PAR-CLIP	23592263
MIRT492588	hsa-miR-520d-5p	PAR-CLIP	23592263
MIRT492587	hsa-miR-524-5p	PAR-CLIP	23592263
MIRT492586	hsa-miR-142-3p	PAR-CLIP	23592263
MIRT098814	hsa-let-7a-3p	PAR-CLIP	23592263
MIRT098815	hsa-let-7b-3p	PAR-CLIP	23592263
MIRT098816	hsa-let-7f-1-3p	PAR-CLIP	23592263
MIRT098818	hsa-miR-98-3p	PAR-CLIP	23592263
MIRT492585	hsa-miR-3591-5p	PAR-CLIP	23592263
MIRT1253267	hsa-miR-103a	CLIP-seq
MIRT1253268	hsa-miR-105	CLIP-seq
MIRT1253269	hsa-miR-107	CLIP-seq
MIRT1253270	hsa-miR-1256	CLIP-seq
MIRT1253271	hsa-miR-1271	CLIP-seq
MIRT1253272	hsa-miR-1305	CLIP-seq
MIRT1253273	hsa-miR-15a	CLIP-seq
MIRT1253274	hsa-miR-15b	CLIP-seq
MIRT1253275	hsa-miR-16	CLIP-seq
MIRT1253276	hsa-miR-182	CLIP-seq
MIRT1253277	hsa-miR-188-5p	CLIP-seq
MIRT1253278	hsa-miR-1911	CLIP-seq
MIRT1253279	hsa-miR-195	CLIP-seq
MIRT1253280	hsa-miR-202	CLIP-seq
MIRT1253281	hsa-miR-204	CLIP-seq
MIRT1253282	hsa-miR-211	CLIP-seq
MIRT1253283	hsa-miR-224	CLIP-seq
MIRT1253284	hsa-miR-27a	CLIP-seq
MIRT1253285	hsa-miR-27b	CLIP-seq
MIRT1253286	hsa-miR-3064-5p	CLIP-seq
MIRT1253287	hsa-miR-3074-3p	CLIP-seq
MIRT1253288	hsa-miR-30a	CLIP-seq
MIRT1253289	hsa-miR-30b	CLIP-seq
MIRT1253290	hsa-miR-30c	CLIP-seq
MIRT1253291	hsa-miR-30d	CLIP-seq
MIRT1253292	hsa-miR-30e	CLIP-seq
MIRT1253293	hsa-miR-3120-3p	CLIP-seq
MIRT1253294	hsa-miR-3143	CLIP-seq
MIRT1253295	hsa-miR-3145-3p	CLIP-seq
MIRT1253296	hsa-miR-320e	CLIP-seq
MIRT1253297	hsa-miR-3646	CLIP-seq
MIRT1253298	hsa-miR-3674	CLIP-seq
MIRT1253299	hsa-miR-382	CLIP-seq
MIRT1253300	hsa-miR-3923	CLIP-seq
MIRT1253301	hsa-miR-3924	CLIP-seq
MIRT1253302	hsa-miR-3942-5p	CLIP-seq
MIRT1253303	hsa-miR-410	CLIP-seq
MIRT1253304	hsa-miR-421	CLIP-seq
MIRT1253305	hsa-miR-424	CLIP-seq
MIRT1253306	hsa-miR-4310	CLIP-seq
MIRT1253307	hsa-miR-4502	CLIP-seq
MIRT1253308	hsa-miR-4509	CLIP-seq
MIRT1253309	hsa-miR-4642	CLIP-seq
MIRT1253310	hsa-miR-4659a-5p	CLIP-seq
MIRT1253311	hsa-miR-4659b-5p	CLIP-seq
MIRT1253312	hsa-miR-4666-3p	CLIP-seq
MIRT1253313	hsa-miR-4672	CLIP-seq
MIRT1253314	hsa-miR-4699-3p	CLIP-seq
MIRT1253315	hsa-miR-4703-5p	CLIP-seq
MIRT1253316	hsa-miR-4704-3p	CLIP-seq
MIRT1253317	hsa-miR-4709-5p	CLIP-seq
MIRT1253318	hsa-miR-4719	CLIP-seq
MIRT1253319	hsa-miR-4729	CLIP-seq
MIRT1253320	hsa-miR-4742-3p	CLIP-seq
MIRT1253321	hsa-miR-4744	CLIP-seq
MIRT1253322	hsa-miR-4776-3p	CLIP-seq
MIRT1253323	hsa-miR-4795-3p	CLIP-seq
MIRT1253324	hsa-miR-497	CLIP-seq
MIRT1253325	hsa-miR-500a	CLIP-seq
MIRT1253326	hsa-miR-513a-5p	CLIP-seq
MIRT1253327	hsa-miR-543	CLIP-seq
MIRT1253328	hsa-miR-545	CLIP-seq
MIRT1253329	hsa-miR-548p	CLIP-seq
MIRT1253330	hsa-miR-548u	CLIP-seq
MIRT1253331	hsa-miR-600	CLIP-seq
MIRT1253332	hsa-miR-96	CLIP-seq
MIRT1253267	hsa-miR-103a	CLIP-seq
MIRT1253269	hsa-miR-107	CLIP-seq
MIRT1253270	hsa-miR-1256	CLIP-seq
MIRT1253271	hsa-miR-1271	CLIP-seq
MIRT2301553	hsa-miR-128	CLIP-seq
MIRT1253272	hsa-miR-1305	CLIP-seq
MIRT2301554	hsa-miR-1343	CLIP-seq
MIRT1253273	hsa-miR-15a	CLIP-seq
MIRT1253274	hsa-miR-15b	CLIP-seq
MIRT1253275	hsa-miR-16	CLIP-seq
MIRT1253276	hsa-miR-182	CLIP-seq
MIRT1253279	hsa-miR-195	CLIP-seq
MIRT1253280	hsa-miR-202	CLIP-seq
MIRT1253283	hsa-miR-224	CLIP-seq
MIRT1253284	hsa-miR-27a	CLIP-seq
MIRT1253285	hsa-miR-27b	CLIP-seq
MIRT2301555	hsa-miR-3074-5p	CLIP-seq
MIRT1253288	hsa-miR-30a	CLIP-seq
MIRT1253289	hsa-miR-30b	CLIP-seq
MIRT1253290	hsa-miR-30c	CLIP-seq
MIRT1253291	hsa-miR-30d	CLIP-seq
MIRT1253292	hsa-miR-30e	CLIP-seq
MIRT2301556	hsa-miR-3124-3p	CLIP-seq
MIRT1253294	hsa-miR-3143	CLIP-seq
MIRT2301557	hsa-miR-3160-5p	CLIP-seq
MIRT2301558	hsa-miR-3613-3p	CLIP-seq
MIRT1253297	hsa-miR-3646	CLIP-seq
MIRT1253300	hsa-miR-3923	CLIP-seq
MIRT1253301	hsa-miR-3924	CLIP-seq
MIRT2301559	hsa-miR-3941	CLIP-seq
MIRT1253303	hsa-miR-410	CLIP-seq
MIRT1253304	hsa-miR-421	CLIP-seq
MIRT1253305	hsa-miR-424	CLIP-seq
MIRT1253306	hsa-miR-4310	CLIP-seq
MIRT2301560	hsa-miR-4480	CLIP-seq
MIRT1253309	hsa-miR-4642	CLIP-seq
MIRT2301561	hsa-miR-4643	CLIP-seq
MIRT1253310	hsa-miR-4659a-5p	CLIP-seq
MIRT1253311	hsa-miR-4659b-5p	CLIP-seq
MIRT2301562	hsa-miR-466	CLIP-seq
MIRT1253312	hsa-miR-4666-3p	CLIP-seq
MIRT1253313	hsa-miR-4672	CLIP-seq
MIRT2301563	hsa-miR-4686	CLIP-seq
MIRT1253316	hsa-miR-4704-3p	CLIP-seq
MIRT1253317	hsa-miR-4709-5p	CLIP-seq
MIRT1253318	hsa-miR-4719	CLIP-seq
MIRT1253319	hsa-miR-4729	CLIP-seq
MIRT1253322	hsa-miR-4776-3p	CLIP-seq
MIRT2301564	hsa-miR-4789-3p	CLIP-seq
MIRT2301565	hsa-miR-489	CLIP-seq
MIRT1253324	hsa-miR-497	CLIP-seq
MIRT1253326	hsa-miR-513a-5p	CLIP-seq
MIRT2301566	hsa-miR-568	CLIP-seq
MIRT1253331	hsa-miR-600	CLIP-seq
MIRT1253332	hsa-miR-96	CLIP-seq
MIRT2301554	hsa-miR-1343	CLIP-seq
MIRT1253277	hsa-miR-188-5p	CLIP-seq
MIRT1253278	hsa-miR-1911	CLIP-seq
MIRT1253281	hsa-miR-204	CLIP-seq
MIRT1253282	hsa-miR-211	CLIP-seq
MIRT1253286	hsa-miR-3064-5p	CLIP-seq
MIRT2301555	hsa-miR-3074-5p	CLIP-seq
MIRT2301556	hsa-miR-3124-3p	CLIP-seq
MIRT1253295	hsa-miR-3145-3p	CLIP-seq
MIRT2301557	hsa-miR-3160-5p	CLIP-seq
MIRT2598248	hsa-miR-3162-5p	CLIP-seq
MIRT1253296	hsa-miR-320e	CLIP-seq
MIRT2598249	hsa-miR-4419a	CLIP-seq
MIRT2598250	hsa-miR-4471	CLIP-seq
MIRT1253307	hsa-miR-4502	CLIP-seq
MIRT2598251	hsa-miR-4510	CLIP-seq
MIRT2598252	hsa-miR-4512	CLIP-seq
MIRT1253313	hsa-miR-4672	CLIP-seq
MIRT2301563	hsa-miR-4686	CLIP-seq
MIRT1253314	hsa-miR-4699-3p	CLIP-seq
MIRT1253319	hsa-miR-4729	CLIP-seq
MIRT1253320	hsa-miR-4742-3p	CLIP-seq
MIRT1253323	hsa-miR-4795-3p	CLIP-seq
MIRT2598253	hsa-miR-4799-5p	CLIP-seq
MIRT2598254	hsa-miR-642b	CLIP-seq
MIRT2598255	hsa-miR-944	CLIP-seq
MIRT2301554	hsa-miR-1343	CLIP-seq
MIRT1253277	hsa-miR-188-5p	CLIP-seq
MIRT1253278	hsa-miR-1911	CLIP-seq
MIRT1253281	hsa-miR-204	CLIP-seq
MIRT1253282	hsa-miR-211	CLIP-seq
MIRT1253286	hsa-miR-3064-5p	CLIP-seq
MIRT2301555	hsa-miR-3074-5p	CLIP-seq
MIRT2301556	hsa-miR-3124-3p	CLIP-seq
MIRT1253295	hsa-miR-3145-3p	CLIP-seq
MIRT2301557	hsa-miR-3160-5p	CLIP-seq
MIRT2598248	hsa-miR-3162-5p	CLIP-seq
MIRT1253296	hsa-miR-320e	CLIP-seq
MIRT2598249	hsa-miR-4419a	CLIP-seq
MIRT2598250	hsa-miR-4471	CLIP-seq
MIRT1253307	hsa-miR-4502	CLIP-seq
MIRT2598251	hsa-miR-4510	CLIP-seq
MIRT2598252	hsa-miR-4512	CLIP-seq
MIRT1253313	hsa-miR-4672	CLIP-seq
MIRT2301563	hsa-miR-4686	CLIP-seq
MIRT1253314	hsa-miR-4699-3p	CLIP-seq
MIRT1253319	hsa-miR-4729	CLIP-seq
MIRT1253320	hsa-miR-4742-3p	CLIP-seq
MIRT1253323	hsa-miR-4795-3p	CLIP-seq
MIRT2598253	hsa-miR-4799-5p	CLIP-seq
MIRT2598254	hsa-miR-642b	CLIP-seq
MIRT2598255	hsa-miR-944	CLIP-seq

Show/Hide all(8)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000413	Process	Protein peptidyl-prolyl isomerization	IEA
GO:0003723	Function	RNA binding	HDA	22658674, 22681889
GO:0003755	Function	Peptidyl-prolyl cis-trans isomerase activity	IEA
GO:0005515	Function	Protein binding	IPI	32296183
GO:0005634	Component	Nucleus	IBA	21873635
GO:0005654	Component	Nucleoplasm	IDA
GO:0005829	Component	Cytosol	IDA
GO:1901407	Process	Regulation of phosphorylation of RNA polymerase II C-terminal domain	IBA	21873635

MIM	HGNC	e!Ensembl
607609	15702	ENSG00000131013

Protein

UniProt ID

Q8WUA2

Protein name

Peptidyl-prolyl cis-trans isomerase-like 4 (PPIase) (EC 5.2.1.8) (Cyclophilin-like protein PPIL4) (Rotamase PPIL4)

Protein function

PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides (By similarity).

PDB

7QTT , 8CH6 , 8I0S , 8I0T , 8I0U , 8I0V

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00160	Pro_isomerase	2 → 161	Cyclophilin type peptidyl-prolyl cis-trans isomerase/CLD	Domain
PF00076	RRM_1	242 → 312	RNA recognition motif. (a.k.a. RRM, RBD, or RNP domain)	Domain

Tissue specificity

TISSUE SPECIFICITY: Abundantly expressed in kidney but has a ubiquitously low expression pattern in other adult tissues. {ECO:0000269|PubMed:11978968}.

Sequence

MAVLLETTLGDVVIDLYTEERPRACLNFLKLCKIKYYNYCLIHNVQRDFIIQTGDPTGTG
RGGESIFGQLYGDQASFFEAEKVPRIKHKKKGTVSMVNNGSDQHGSQFLITTGENLDYLD
GVHTVFGEVTEGMDIIKKINETFVDKDFVPYQDIRINHTVILDDPFDDPPDLLIPDRSPE
PTREQLDSGRIGADEEIDDFKGRSAEEVEEIKAEKEAKTQAILLEMVGDLPDADIKPPEN
VLFVCKLNPVTTDEDLEIIFSRFGPIRSCEVIRDWKTGESLCYAFIEFEKEEDCEKAFFK
MDNVLIDDRRIHVDFSQSVAKVKWKGKGGKYTKSDFKEYEKEQDKPPNLVLKDKVKPKQD
TKYDLILDEQAEDSKSSHSHTSKKHKKKTHHCSEEKEDEDYMPIKNTNQDIYREMGFGHY
EEEESCWEKQKSEKRDRTQNRSRSRSRERDGHYSNSHKSKYQTDLYERERSKKRDRSRSP
KKSKDKEKSKYR

Sequence length

492

Interactions

View interactions

	Reactome
			mRNA Splicing - Major Pathway

Show/Hide Causal Diseases (1)

Disease term	Disease name	dbSNP ID	References
Causal
Rheumatoid arthritis	Rheumatoid Arthritis	rs587776843	24390342, 30423114

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Glioblastoma	Glioblastoma	CRISPR screening of E3 ubiquitin ligases reveals Ring Finger Protein 185 as a novel tumor suppressor in glioblastoma repressed by promoter hypermethylation and miR-587		GWAS, CBGDA

Show/Hide Text Mining Associations (2)

Disease Name	Relationship Type	References
Associations from Text Mining
Cerebral Hemorrhage	Associate	34887573
Intracranial Aneurysm	Associate	34887573

PPIL4 (peptidylprolyl isomerase like 4)