Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
84992
Gene name Gene Name - the full gene name approved by the HGNC.
Phosphatidylinositol glycan anchor biosynthesis class Y
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
PIGY
Synonyms (NCBI Gene) Gene synonyms aliases
HPMRS6, PIG-Y
Disease Acronyms (UniProt) Disease acronyms from UniProt database
HPMRS6
Chromosome Chromosome number
4
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
4q22.1
Summary Summary of gene provided in NCBI Entrez Gene.
The protein encoded by this gene is part of the GPI-N-acetylglucosaminyltransferase (GIP-GnT) complex which initiates the biosynthesis of glycosylphosphatidylinositol (GPI). GPI is synthesized in the endoplasmic reticulum and serves as an anchor for many
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT1233734 hsa-miR-105 CLIP-seq
MIRT1233735 hsa-miR-1273g CLIP-seq
MIRT1233736 hsa-miR-134 CLIP-seq
MIRT1233737 hsa-miR-137 CLIP-seq
MIRT1233738 hsa-miR-188-3p CLIP-seq
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0000506 Component Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex IBA 21873635
GO:0000506 Component Glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex IDA 16162815
GO:0005515 Function Protein binding IPI 16162815, 32296183
GO:0005789 Component Endoplasmic reticulum membrane IDA 16162815
GO:0005789 Component Endoplasmic reticulum membrane TAS
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
610662 28213 ENSG00000255072
Protein
UniProt ID Q3MUY2
Protein name Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y (Phosphatidylinositol-glycan biosynthesis class Y protein) (PIG-Y)
Protein function Part of the glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex that catalyzes the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine to phosphatidylinositol and participates in the first step of GPI biosynth
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15159 PIG-Y 2 70 Phosphatidylinositol N-acetylglucosaminyltransferase subunit Y Family
Sequence
Sequence length 71
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  KEGG   Reactome
  Glycosylphosphatidylinositol (GPI)-anchor biosynthesis
Metabolic pathways
  Synthesis of glycosylphosphatidylinositol (GPI)
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Autism Autistic behavior rs121964908, rs62643608, rs181327458, rs797046134, rs869312704, rs1555013332, rs876657679, rs1057518999, rs1057518658, rs771827120, rs1555187899, rs773080572, rs753871454, rs1684130791, rs1684180699
View all (8 more)
Developmental delay Global developmental delay rs28941770, rs199469464, rs281865469, rs143747297, rs398123009, rs587777428, rs786205133, rs606231459, rs797044854, rs797045027, rs864309504, rs878853160, rs886039902, rs886042046, rs886041291
View all (32 more)
Developmental regression Developmental regression rs1224421127
Glycosylphosphatidylinositol deficiency Glycosylphosphatidylinositol deficiency rs1010907740, rs1554764080, rs1554764067, rs782768127, rs782220208, rs1553259614, rs1553259602, rs782615259, rs761543313, rs776038451, rs1263517814, rs1567618413, rs1567614073, rs1426262136, rs1567616570
View all (3 more)
26293662
Unknown
Disease term Disease name Evidence References Source
Hyperphosphatasia With Mental Retardation hyperphosphatasia with intellectual disability syndrome 6, hyperphosphatasia-intellectual disability syndrome GenCC
Associations from Text Mining
Disease Name Relationship Type References
adult multisystem inflammatory disease COVID 19 related Associate 26293662
Body Dysmorphic Disorders Associate 26293662
Burkitt Lymphoma Associate 19302917
Cataract Associate 26293662
Death Associate 26293662
Developmental Disabilities Associate 26293662
Glycosylphosphatidylinositol deficiency Associate 19302917
Hyperostosis corticalis deformans juvenilis Associate 30813920
Hyperphosphatasia with Mental Retardation Associate 30813920
Immunologic Deficiency Syndromes Associate 26293662