Gene Gene information from NCBI Gene database.
Entrez ID 84966
Gene name Immunoglobin superfamily member 21
Gene symbol IGSF21
Synonyms (NCBI Gene)
-
Chromosome 1
Chromosome location 1p36.13
Summary This gene encodes a protein which has two immunoglobulin (Ig) domains and is a member of the immunoglobulin superfamily. Proteins in this superfamily are usually found on or in cell membranes and act as receptors in immune response pathways. [provided by
miRNA miRNA information provided by mirtarbase database.
1
miRTarBase ID miRNA Experiments Reference
MIRT019159 hsa-miR-335-5p Microarray 18185580
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
20
GO ID Ontology Definition Evidence Reference
GO:0005886 Component Plasma membrane IBA
GO:0005886 Component Plasma membrane IEA
GO:0009897 Component External side of plasma membrane IEA
GO:0009897 Component External side of plasma membrane ISS
GO:0016020 Component Membrane IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
HGNC N/A HGNC
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96ID5
Protein name Immunoglobulin superfamily member 21 (IgSF21)
Protein function Involved in synaptic inhibition in the brain. Selectively regulates inhibitory presynaptic differentiation through interacting with presynaptic NRXN2.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF07686 V-set 31 134 Immunoglobulin V-set domain Domain
Sequence
MRTAPSLRRCVCLLLAAILDLARGYLTVNIEPLPPVVAGDAVTLKCNFKTDGRMREIVWY
RVTDGGTIKQKIFTFDAMFSTNYSHMENYRKREDLVYQSTVRLPEVRISDNGPYECHVGI
YDRATREKVVLASG
NIFLNVMAPPTSIEVVAADTPAPFSRYQAQNFTLVCIVSGGKPAPM
VYFKRDGEPIDAVPLSEPPAASSGPLQDSRPFRSLLHRDLDDTKMQKSLSLLDAENRGGR
PYTERPSRGLTPDPNILLQPTTENIPETVVSREFPRWVHSAEPTYFLRHSRTPSSDGTVE
VRALLTWTLNPQIDNEALFSCEVKHPALSMPMQAEVTLVAPKGPKIVMTPSRARVGDTVR
ILVHGFQNEVFPEPMFTWTRVGSRLLDGSAEFDGKELVLERVPAELNGSMYRCTAQNPLG
STDTHTRLIVFENPNIPRGTEDSNGSIGPTGARLTLVLALTVILELT
Sequence length 467
Interactions View interactions