Gene Gene information from NCBI Gene database.
Entrez ID 84961
Gene name F-box and leucine rich repeat protein 20
Gene symbol FBXL20
Synonyms (NCBI Gene)
Fbl2Fbl20
Chromosome 17
Chromosome location 17q12
Summary Members of the F-box protein family, such as FBXL20, are characterized by an approximately 40-amino acid F-box motif. SCF complexes, formed by SKP1 (MIM 601434), cullin (see CUL1; MIM 603134), and F-box proteins, act as protein-ubiquitin ligases. F-box pr
miRNA miRNA information provided by mirtarbase database.
1883
miRTarBase ID miRNA Experiments Reference
MIRT046059 hsa-miR-125b-5p CLASH 23622248
MIRT709424 hsa-miR-624-5p HITS-CLIP 19536157
MIRT709423 hsa-miR-6838-3p HITS-CLIP 19536157
MIRT709422 hsa-miR-554 HITS-CLIP 19536157
MIRT709421 hsa-miR-517-5p HITS-CLIP 19536157
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
12
GO ID Ontology Definition Evidence Reference
GO:0001662 Process Behavioral fear response IEA
GO:0005515 Function Protein binding IPI 27705803, 32296183, 33961781, 34731788
GO:0005737 Component Cytoplasm IEA
GO:0005829 Component Cytosol TAS
GO:0019005 Component SCF ubiquitin ligase complex IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
609086 24679 ENSG00000108306
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q96IG2
Protein name F-box/LRR-repeat protein 20 (F-box and leucine-rich repeat protein 20) (F-box/LRR-repeat protein 2-like)
Protein function Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission (By similarity).
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF12937 F-box-like 26 70 F-box-like Domain
PF13516 LRR_6 141 165 Leucine Rich repeat Repeat
PF13516 LRR_6 167 191 Leucine Rich repeat Repeat
PF13516 LRR_6 219 243 Leucine Rich repeat Repeat
PF13516 LRR_6 323 347 Leucine Rich repeat Repeat
Sequence
MRRDVNGVTKSRFEMFSNSDEAVINKKLPKELLLRIFSFLDVVTLCRCAQVSRAWNVLAL
DGSNWQRIDL
FDFQRDIEGRVVENISKRCGGFLRKLSLRGCLGVGDNALRTFAQNCRNIE
VLNLNGCTKTTDATCTSLSKFCSKLRHLDLASCTSITNMSLKALSEGCPLLEQLNISWCD
QVTKDGIQALV
RGCGGLKALFLKGCTQLEDEALKYIGAHCPELVTLNLQTCLQITDEGLI
TIC
RGCHKLQSLCASGCSNITDAILNALGQNCPRLRILEVARCSQLTDVGFTTLARNCHE
LEKMDLEECVQITDSTLIQLSIHCPRLQVLSLSHCELITDDGIRHLGNGACAHDQLEVIE
LDNCPLITDASLEHLKSCHSLERIELYDCQQITRAGIKRLRTHLPNIKVHAYFAPVTPPP
SVGGSRQRFCRCCIIL
Sequence length 436
Interactions View interactions
Pathways Pathway information has different metabolic/signaling pathways associated with genes.
  Reactome
    Neddylation
Antigen processing: Ubiquitination & Proteasome degradation