TNS4 (tensin 4)

Gene

• Entrez ID: 84951
• Gene name: Tensin 4
• Gene symbol: TNS4
• Synonyms (NCBI Gene): CTEN, PP14434
• Chromosome: 17
• Chromosome location: 17q21.2

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT003769	hsa-miR-1-3p	Microarray	15685193
MIRT018760	hsa-miR-335-5p	Microarray	18185580
MIRT023010	hsa-miR-124-3p	Microarray	18668037
MIRT003769	hsa-miR-1-3p	Microarray	15685193
MIRT030073	hsa-miR-26b-5p	Microarray	19088304
MIRT608454	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT608453	hsa-miR-6874-5p	HITS-CLIP	23824327
MIRT608452	hsa-miR-4455	HITS-CLIP	23824327
MIRT608451	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT652291	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT652290	hsa-miR-1910-5p	HITS-CLIP	23824327
MIRT652289	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT652288	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT652287	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT652286	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT652285	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT652284	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT652283	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT641607	hsa-miR-890	HITS-CLIP	23824327
MIRT641606	hsa-miR-4293	HITS-CLIP	23824327
MIRT641605	hsa-miR-5690	HITS-CLIP	23824327
MIRT641604	hsa-miR-544b	HITS-CLIP	23824327
MIRT641603	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT641602	hsa-miR-1827	HITS-CLIP	23824327
MIRT641601	hsa-miR-6827-5p	HITS-CLIP	23824327
MIRT641600	hsa-miR-6090	HITS-CLIP	23824327
MIRT641599	hsa-miR-4300	HITS-CLIP	23824327
MIRT641598	hsa-miR-5591-5p	HITS-CLIP	23824327
MIRT641597	hsa-miR-6726-5p	HITS-CLIP	23824327
MIRT641596	hsa-miR-920	HITS-CLIP	23824327
MIRT641594	hsa-miR-7977	HITS-CLIP	23824327
MIRT641595	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT641593	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT641591	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT641592	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT641590	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT641589	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT641588	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT641587	hsa-miR-3689c	HITS-CLIP	23824327
MIRT641585	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT641586	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT641584	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT608454	hsa-miR-6867-5p	HITS-CLIP	24906430
MIRT608453	hsa-miR-6874-5p	HITS-CLIP	24906430
MIRT608452	hsa-miR-4455	HITS-CLIP	24906430
MIRT608451	hsa-miR-574-5p	HITS-CLIP	24906430
MIRT608452	hsa-miR-4455	HITS-CLIP	27418678
MIRT608452	hsa-miR-4455	HITS-CLIP	27418678
MIRT608452	hsa-miR-4455	HITS-CLIP	27418678
MIRT608451	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT608451	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT608451	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT608454	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT608454	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT608454	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT608453	hsa-miR-6874-5p	HITS-CLIP	27418678
MIRT608453	hsa-miR-6874-5p	HITS-CLIP	27418678
MIRT608453	hsa-miR-6874-5p	HITS-CLIP	27418678
MIRT739215	hsa-miR-433	HITS-CLIP	33718276
MIRT608454	hsa-miR-6867-5p	HITS-CLIP	23824327
MIRT608453	hsa-miR-6874-5p	HITS-CLIP	23824327
MIRT608452	hsa-miR-4455	HITS-CLIP	23824327
MIRT608451	hsa-miR-574-5p	HITS-CLIP	23824327
MIRT652291	hsa-miR-455-3p	HITS-CLIP	23824327
MIRT652290	hsa-miR-1910-5p	HITS-CLIP	23824327
MIRT652289	hsa-miR-3691-3p	HITS-CLIP	23824327
MIRT652288	hsa-miR-6814-5p	HITS-CLIP	23824327
MIRT652287	hsa-miR-3127-3p	HITS-CLIP	23824327
MIRT652286	hsa-miR-6756-3p	HITS-CLIP	23824327
MIRT652285	hsa-miR-150-5p	HITS-CLIP	23824327
MIRT652284	hsa-miR-6515-3p	HITS-CLIP	23824327
MIRT652283	hsa-miR-1236-3p	HITS-CLIP	23824327
MIRT641607	hsa-miR-890	HITS-CLIP	23824327
MIRT641606	hsa-miR-4293	HITS-CLIP	23824327
MIRT641605	hsa-miR-5690	HITS-CLIP	23824327
MIRT641604	hsa-miR-544b	HITS-CLIP	23824327
MIRT641603	hsa-miR-4649-3p	HITS-CLIP	23824327
MIRT641602	hsa-miR-1827	HITS-CLIP	23824327
MIRT641601	hsa-miR-6827-5p	HITS-CLIP	23824327
MIRT641600	hsa-miR-6090	HITS-CLIP	23824327
MIRT641599	hsa-miR-4300	HITS-CLIP	23824327
MIRT641598	hsa-miR-5591-5p	HITS-CLIP	23824327
MIRT641597	hsa-miR-6726-5p	HITS-CLIP	23824327
MIRT641596	hsa-miR-920	HITS-CLIP	23824327
MIRT641594	hsa-miR-7977	HITS-CLIP	23824327
MIRT641595	hsa-miR-30c-1-3p	HITS-CLIP	23824327
MIRT641593	hsa-miR-30c-2-3p	HITS-CLIP	23824327
MIRT641591	hsa-miR-6788-5p	HITS-CLIP	23824327
MIRT641592	hsa-miR-1273h-5p	HITS-CLIP	23824327
MIRT641590	hsa-miR-30b-3p	HITS-CLIP	23824327
MIRT641589	hsa-miR-3689a-3p	HITS-CLIP	23824327
MIRT641588	hsa-miR-3689b-3p	HITS-CLIP	23824327
MIRT641587	hsa-miR-3689c	HITS-CLIP	23824327
MIRT641585	hsa-miR-6779-5p	HITS-CLIP	23824327
MIRT641586	hsa-miR-6780a-5p	HITS-CLIP	23824327
MIRT641584	hsa-miR-887-5p	HITS-CLIP	23824327
MIRT1445759	hsa-miR-1225-3p	CLIP-seq
MIRT1445760	hsa-miR-1226	CLIP-seq
MIRT1445761	hsa-miR-1262	CLIP-seq
MIRT1445762	hsa-miR-1268	CLIP-seq
MIRT1445763	hsa-miR-1268b	CLIP-seq
MIRT1445764	hsa-miR-127-5p	CLIP-seq
MIRT1445765	hsa-miR-1294	CLIP-seq
MIRT1445766	hsa-miR-2052	CLIP-seq
MIRT1445767	hsa-miR-223	CLIP-seq
MIRT1445768	hsa-miR-2276	CLIP-seq
MIRT1445769	hsa-miR-2467-5p	CLIP-seq
MIRT1445770	hsa-miR-3064-5p	CLIP-seq
MIRT1445771	hsa-miR-3120-5p	CLIP-seq
MIRT1445772	hsa-miR-3157-5p	CLIP-seq
MIRT1445773	hsa-miR-3184	CLIP-seq
MIRT1445774	hsa-miR-3188	CLIP-seq
MIRT1445775	hsa-miR-3192	CLIP-seq
MIRT1445776	hsa-miR-3613-3p	CLIP-seq
MIRT1445777	hsa-miR-3664-5p	CLIP-seq
MIRT1445778	hsa-miR-3672	CLIP-seq
MIRT1445779	hsa-miR-3674	CLIP-seq
MIRT1445780	hsa-miR-371-5p	CLIP-seq
MIRT1445781	hsa-miR-371b-5p	CLIP-seq
MIRT1445782	hsa-miR-3975	CLIP-seq
MIRT1445783	hsa-miR-423-5p	CLIP-seq
MIRT1445784	hsa-miR-4269	CLIP-seq
MIRT1445785	hsa-miR-4277	CLIP-seq
MIRT1445786	hsa-miR-4316	CLIP-seq
MIRT1445787	hsa-miR-4433	CLIP-seq
MIRT1445788	hsa-miR-4459	CLIP-seq
MIRT1445789	hsa-miR-4474-3p	CLIP-seq
MIRT1445790	hsa-miR-4522	CLIP-seq
MIRT1445791	hsa-miR-4645-3p	CLIP-seq
MIRT1445792	hsa-miR-4677-3p	CLIP-seq
MIRT1445793	hsa-miR-4687-3p	CLIP-seq
MIRT1445794	hsa-miR-4701-3p	CLIP-seq
MIRT1445795	hsa-miR-4728-5p	CLIP-seq
MIRT1445796	hsa-miR-4731-5p	CLIP-seq
MIRT1445797	hsa-miR-4768-3p	CLIP-seq
MIRT1445798	hsa-miR-4786-3p	CLIP-seq
MIRT1445799	hsa-miR-485-5p	CLIP-seq
MIRT1445800	hsa-miR-486-3p	CLIP-seq
MIRT1445801	hsa-miR-526b	CLIP-seq
MIRT1445802	hsa-miR-542-3p	CLIP-seq
MIRT1445803	hsa-miR-548c-3p	CLIP-seq
MIRT1445804	hsa-miR-563	CLIP-seq
MIRT1445805	hsa-miR-604	CLIP-seq
MIRT1445806	hsa-miR-644	CLIP-seq
MIRT1445807	hsa-miR-647	CLIP-seq
MIRT1445808	hsa-miR-661	CLIP-seq
MIRT1445809	hsa-miR-665	CLIP-seq
MIRT1445810	hsa-miR-940	CLIP-seq
MIRT1445761	hsa-miR-1262	CLIP-seq
MIRT1445762	hsa-miR-1268	CLIP-seq
MIRT1445763	hsa-miR-1268b	CLIP-seq
MIRT2133239	hsa-miR-1972	CLIP-seq
MIRT1445772	hsa-miR-3157-5p	CLIP-seq
MIRT1445773	hsa-miR-3184	CLIP-seq
MIRT2133240	hsa-miR-342-5p	CLIP-seq
MIRT1445778	hsa-miR-3672	CLIP-seq
MIRT2133241	hsa-miR-3688-3p	CLIP-seq
MIRT2133242	hsa-miR-3689d	CLIP-seq
MIRT1445783	hsa-miR-423-5p	CLIP-seq
MIRT2133243	hsa-miR-4267	CLIP-seq
MIRT2133244	hsa-miR-4446-3p	CLIP-seq
MIRT2133245	hsa-miR-4447	CLIP-seq
MIRT2133246	hsa-miR-4472	CLIP-seq
MIRT1445790	hsa-miR-4522	CLIP-seq
MIRT1445791	hsa-miR-4645-3p	CLIP-seq
MIRT2133247	hsa-miR-4650-5p	CLIP-seq
MIRT2133248	hsa-miR-4651	CLIP-seq
MIRT2133249	hsa-miR-4664-5p	CLIP-seq
MIRT1445794	hsa-miR-4701-3p	CLIP-seq
MIRT1445795	hsa-miR-4728-5p	CLIP-seq
MIRT1445799	hsa-miR-485-5p	CLIP-seq
MIRT1445802	hsa-miR-542-3p	CLIP-seq
MIRT2133250	hsa-miR-608	CLIP-seq
MIRT1445808	hsa-miR-661	CLIP-seq
MIRT2133251	hsa-miR-936	CLIP-seq
MIRT2354485	hsa-miR-1228	CLIP-seq
MIRT2354486	hsa-miR-1293	CLIP-seq
MIRT2354487	hsa-miR-22	CLIP-seq
MIRT2354488	hsa-miR-302f	CLIP-seq
MIRT1445770	hsa-miR-3064-5p	CLIP-seq
MIRT2354489	hsa-miR-3157-3p	CLIP-seq
MIRT1445772	hsa-miR-3157-5p	CLIP-seq
MIRT2354490	hsa-miR-3160-3p	CLIP-seq
MIRT1445775	hsa-miR-3192	CLIP-seq
MIRT2133240	hsa-miR-342-5p	CLIP-seq
MIRT2133242	hsa-miR-3689d	CLIP-seq
MIRT2133245	hsa-miR-4447	CLIP-seq
MIRT2133246	hsa-miR-4472	CLIP-seq
MIRT2354491	hsa-miR-4483	CLIP-seq
MIRT2354492	hsa-miR-4487	CLIP-seq
MIRT2354493	hsa-miR-4505	CLIP-seq
MIRT2133248	hsa-miR-4651	CLIP-seq
MIRT2354494	hsa-miR-4663	CLIP-seq
MIRT2133249	hsa-miR-4664-5p	CLIP-seq
MIRT1445795	hsa-miR-4728-5p	CLIP-seq
MIRT1445799	hsa-miR-485-5p	CLIP-seq
MIRT2354495	hsa-miR-490-3p	CLIP-seq
MIRT2354496	hsa-miR-558	CLIP-seq
MIRT2133250	hsa-miR-608	CLIP-seq
MIRT1445808	hsa-miR-661	CLIP-seq
MIRT1445810	hsa-miR-940	CLIP-seq
MIRT1445761	hsa-miR-1262	CLIP-seq
MIRT2354486	hsa-miR-1293	CLIP-seq
MIRT1445772	hsa-miR-3157-5p	CLIP-seq
MIRT2133240	hsa-miR-342-5p	CLIP-seq
MIRT2396190	hsa-miR-3679-3p	CLIP-seq
MIRT2133242	hsa-miR-3689d	CLIP-seq
MIRT2396191	hsa-miR-4418	CLIP-seq
MIRT2133245	hsa-miR-4447	CLIP-seq
MIRT2133246	hsa-miR-4472	CLIP-seq
MIRT2354491	hsa-miR-4483	CLIP-seq
MIRT2396192	hsa-miR-4492	CLIP-seq
MIRT2396193	hsa-miR-4498	CLIP-seq
MIRT2354493	hsa-miR-4505	CLIP-seq
MIRT2133248	hsa-miR-4651	CLIP-seq
MIRT2133249	hsa-miR-4664-5p	CLIP-seq
MIRT1445794	hsa-miR-4701-3p	CLIP-seq
MIRT1445795	hsa-miR-4728-5p	CLIP-seq
MIRT1445799	hsa-miR-485-5p	CLIP-seq
MIRT2396194	hsa-miR-509-3-5p	CLIP-seq
MIRT2396195	hsa-miR-509-5p	CLIP-seq
MIRT1445802	hsa-miR-542-3p	CLIP-seq
MIRT2133250	hsa-miR-608	CLIP-seq
MIRT1445808	hsa-miR-661	CLIP-seq
MIRT2396196	hsa-miR-762	CLIP-seq
MIRT2462121	hsa-miR-10a	CLIP-seq
MIRT2462122	hsa-miR-10b	CLIP-seq
MIRT1445761	hsa-miR-1262	CLIP-seq
MIRT2462123	hsa-miR-339-5p	CLIP-seq
MIRT2462124	hsa-miR-4421	CLIP-seq
MIRT2462125	hsa-miR-4684-5p	CLIP-seq
MIRT1445794	hsa-miR-4701-3p	CLIP-seq
MIRT1445803	hsa-miR-548c-3p	CLIP-seq
MIRT2462126	hsa-miR-593	CLIP-seq
MIRT2462121	hsa-miR-10a	CLIP-seq
MIRT2462122	hsa-miR-10b	CLIP-seq
MIRT1445761	hsa-miR-1262	CLIP-seq
MIRT1445771	hsa-miR-3120-5p	CLIP-seq
MIRT2648370	hsa-miR-3122	CLIP-seq
MIRT2648371	hsa-miR-3165	CLIP-seq
MIRT2462123	hsa-miR-339-5p	CLIP-seq
MIRT1445776	hsa-miR-3613-3p	CLIP-seq
MIRT1445777	hsa-miR-3664-5p	CLIP-seq
MIRT2648372	hsa-miR-3665	CLIP-seq
MIRT1445778	hsa-miR-3672	CLIP-seq
MIRT1445780	hsa-miR-371-5p	CLIP-seq
MIRT1445781	hsa-miR-371b-5p	CLIP-seq
MIRT2648373	hsa-miR-3913-5p	CLIP-seq
MIRT2462124	hsa-miR-4421	CLIP-seq
MIRT1445790	hsa-miR-4522	CLIP-seq
MIRT2462125	hsa-miR-4684-5p	CLIP-seq
MIRT1445794	hsa-miR-4701-3p	CLIP-seq
MIRT1445795	hsa-miR-4728-5p	CLIP-seq
MIRT2648374	hsa-miR-548aa	CLIP-seq
MIRT2648375	hsa-miR-548ac	CLIP-seq
MIRT2648376	hsa-miR-548ae	CLIP-seq
MIRT2648377	hsa-miR-548aj	CLIP-seq
MIRT2648378	hsa-miR-548am	CLIP-seq
MIRT1445803	hsa-miR-548c-3p	CLIP-seq
MIRT2648379	hsa-miR-548d-3p	CLIP-seq
MIRT2648380	hsa-miR-548x	CLIP-seq
MIRT2648381	hsa-miR-548z	CLIP-seq
MIRT2462126	hsa-miR-593	CLIP-seq
MIRT2462121	hsa-miR-10a	CLIP-seq
MIRT2462122	hsa-miR-10b	CLIP-seq
MIRT1445761	hsa-miR-1262	CLIP-seq
MIRT1445771	hsa-miR-3120-5p	CLIP-seq
MIRT2648370	hsa-miR-3122	CLIP-seq
MIRT2648371	hsa-miR-3165	CLIP-seq
MIRT2462123	hsa-miR-339-5p	CLIP-seq
MIRT1445776	hsa-miR-3613-3p	CLIP-seq
MIRT1445777	hsa-miR-3664-5p	CLIP-seq
MIRT2648372	hsa-miR-3665	CLIP-seq
MIRT1445778	hsa-miR-3672	CLIP-seq
MIRT1445780	hsa-miR-371-5p	CLIP-seq
MIRT1445781	hsa-miR-371b-5p	CLIP-seq
MIRT2648373	hsa-miR-3913-5p	CLIP-seq
MIRT2462124	hsa-miR-4421	CLIP-seq
MIRT1445790	hsa-miR-4522	CLIP-seq
MIRT2462125	hsa-miR-4684-5p	CLIP-seq
MIRT1445794	hsa-miR-4701-3p	CLIP-seq
MIRT1445795	hsa-miR-4728-5p	CLIP-seq
MIRT1445803	hsa-miR-548c-3p	CLIP-seq
MIRT2462126	hsa-miR-593	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003779	Function	Actin binding	IEA
GO:0005515	Function	Protein binding	IPI	16273093, 17190795, 32296183, 34591642
GO:0005737	Component	Cytoplasm	IEA
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0005925	Component	Focal adhesion	IBA
GO:0005925	Component	Focal adhesion	IDA	17190795
GO:0005925	Component	Focal adhesion	IEA
GO:0008104	Process	Intracellular protein localization	IDA	17190795
GO:0070161	Component	Anchoring junction	IEA

Other IDs

• MIM: 608385
• HGNC: 24352
• e!Ensembl: ENSG00000131746

Protein

• UniProt ID: Q8IZW8
• Protein name: Tensin-4 (C-terminal tensin-like protein)
• Protein function: Promotes EGF-induced cell migration by displacing tensin TNS3 from the cytoplasmic tail of integrin ITGB1 which results in dissociation of TNS3 from focal adhesions, disassembly of actin stress fibers and initiation of cell migration (PubMed:176
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00017	SH2	449 → 541	SH2 domain	Domain
  PF08416	PTB	581 → 714	Phosphotyrosine-binding domain	Domain

• Tissue specificity: TISSUE SPECIFICITY: Expressed at low levels in colon (at protein level) (PubMed:19214987, PubMed:19487278). Expressed in prostate and placenta (PubMed:12154022). {ECO:0000269|PubMed:12154022, ECO:0000269|PubMed:19214987, ECO:0000269|PubMed:19487278}.
• Sequence:

  MSQVMSSPLLAGGHAVSLAPCDEPRRTLHPAPSPSLPPQCSYYTTEGWGAQALMAPVPCM
  GPPGRLQQAPQVEAKATCFLPSPGEKALGTPEDLDSYIDFSLESLNQMILELDPTFQLLP
  PGTGGSQAELAQSTMSMRKKEESEALDIKYIEVTSARSRCHDGPQHCSSPSVTPPFGSLR
  SGGLLLSRDVPRETRSSSESLIFSGNQGRGHQRPLPPSEGLSPRPPNSPSISIPCMGSKA
  SSPHGLGSPLVASPRLEKRLGGLAPQRGSRISVLSASPVSDVSYMFGSSQSLLHSSNSSH
  QSSSRSLESPANSSSSLHSLGSVSLCTRPSDFQAPRNPTLTMGQPRTPHSPPLAKEHASS
  CPPSITNSMVDIPIVLINGCPEPGSSPPQRTPGHQNSVQPGAASPSNPCPATRSNSQTLS
  DAPFTTCPEGPARDMQPTMKFVMDTSKYWFKPNITREQAIELLRKEEPGAFVIRDSSSYR
  GSFGLALKVQEVPASAQSRPGEDSNDLIRHFLIESSAKGVHLKGADEEPYFGSLSAFVCQ
  HSIMALALPCKLTIPQRELGGADGASDSTDSPASCQKKSAGCHTLYLSSVSVETLTGALA
  VQKAISTTFERDILPTPTVVHFKVTEQGITLTDVQRKVFFRRHYPLTTLRFCGMDPEQRK
  WQKYCKPSWIFGFVAKSQTEPQENVCHLFAEYDMVQPASQVIGLVTALLQDAERM

• Sequence length: 715

Pathways

Reactome:

MET interacts with TNS proteins

Associated diseases

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Malignant tumor of esophagus	Benign	rs140032692	RCV005903119

Associations from Text Mining
Disease Name	Relationship Type	References
Adenocarcinoma of Lung	Associate	30353687, 33029490, 33195688, 36793937, 39766765
Breast Neoplasms	Stimulate	23774213
Carcinogenesis	Associate	23625726
Carcinoma Hepatocellular	Associate	26035355
Carcinoma Non Small Cell Lung	Associate	29985912, 35807355
Colorectal Neoplasms	Stimulate	19487278
Colorectal Neoplasms	Associate	21698197, 26852686, 30648319, 37328854
Dysplastic Nevus Syndrome	Stimulate	24244691
Hereditary pancreatitis	Stimulate	23625726
Lung Neoplasms	Associate	23774213, 25439778, 29985912
Lymphatic Metastasis	Associate	36793937
Melanoma	Associate	24244691
Neoplasm Metastasis	Associate	29985912, 30648319
Neoplasms	Associate	15001839, 25439778, 29102927, 30353687
Neoplasms	Stimulate	23625726
Neoplasms	Inhibit	24244691
Osteoporosis	Associate	34743649
Pancreatic Neoplasms	Associate	30639415
Prostatic Neoplasms	Associate	19725034
Prostatic Neoplasms	Inhibit	24244691, 26784942
Prostatitis	Inhibit	19487278
Stomach Neoplasms	Associate	29102927
Stomach Neoplasms	Stimulate	36896596
Thymoma	Associate	15001839