Gene Gene information from NCBI Gene database.
Entrez ID 84530
Gene name Serine/arginine repetitive matrix 4
Gene symbol SRRM4
Synonyms (NCBI Gene)
KIAA1853MU-MB-2.76nSR100
Chromosome 12
Chromosome location 12q24.23
Summary SRRM4 promotes alternative splicing and inclusion of neural-specific exons in target mRNAs (Calarco et al., 2009 [PubMed 19737518]).[supplied by OMIM, Oct 2009]
miRNA miRNA information provided by mirtarbase database.
488
miRTarBase ID miRNA Experiments Reference
MIRT622072 hsa-miR-8485 HITS-CLIP 22927820
MIRT653125 hsa-miR-6793-3p HITS-CLIP 22927820
MIRT627515 hsa-miR-4742-3p HITS-CLIP 22927820
MIRT622072 hsa-miR-8485 HITS-CLIP 22927820
MIRT653125 hsa-miR-6793-3p HITS-CLIP 23313552
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
25
GO ID Ontology Definition Evidence Reference
GO:0000381 Process Regulation of alternative mRNA splicing, via spliceosome IDA 29961578
GO:0000381 Process Regulation of alternative mRNA splicing, via spliceosome IEA
GO:0000381 Process Regulation of alternative mRNA splicing, via spliceosome ISS
GO:0003723 Function RNA binding IEA
GO:0003729 Function MRNA binding IBA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
MIM HGNC e!Ensembl
613103 29389 ENSG00000139767
Protein Protein information from UniProt database.
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
A7MD48
Protein name Serine/arginine repetitive matrix protein 4 (Medulloblastoma antigen MU-MB-2.76) (Neural-specific serine/arginine repetitive splicing factor of 100 kDa) (Neural-specific SR-related protein of 100 kDa) (nSR100)
Protein function Splicing factor specifically required for neural cell differentiation. Acts in conjunction with nPTB/PTBP2 by binding directly to its regulated target transcripts and promotes neural-specific exon inclusion in many genes that function in neural
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF15230 SRRM_C 457 522 Serine/arginine repetitive matrix protein C-terminus Family
Tissue specificity TISSUE SPECIFICITY: Specifically expressed in neuronal cells (at protein level). Expressed in the cerebellum. {ECO:0000269|PubMed:12800201, ECO:0000269|PubMed:19737518}.
Sequence
MASVQQGEKQLFEKFWRGTFKAVATPRPESIIVASITARKPLPRTEPQNNPVVPAQDGPS
EKLGQHLATEPLGTNSWERDKTCRELGATRGHSASHDKDLTPPPSSRGKKKKKKSTRKKR
RRSSSYSPSPVKKKKKKSSKKHKRRRSFSKKRRHSSSSPKSKRRDEKRHKKQSRSRPRKS
HRHRHHRCPSRSQSSESRPSSCESRHRGRSPEEGQKSRRRHSRRCSKTLCKDSPEAQSSR
PPSQPLQMLGYLSARGVITGSGSAADLFTKTASPLTTSRGRSQEYDSGNDTSSPPSTQTS
SARSRGQEKGSPSGGLSKSRELNSGNTSDSGNSFTTSSPQNKGAMLENLSPTSRGRESRG
FQSPCLECAEVKKSSLVPSTARSSPMKGCSRSSSYASTRSSSHSSRSPNPRASPRYTQSR
STSSEKRSYSRSPSYSSKSGKRSPPSRSSRSRRSPSYSRYSPSRERDPKYSEKDSQQRER
ERARRRRRSYSPMRKRRRDSPSHLEARRITSARKRPIPYYRP
SPSSSGSLSSTSSWYSSS
SSRSASRSYSRSRSRSRSRRRSRTRTSSSSSSRSPSPGSRSRSRSRSRSRSRSRSQSRSY
SSADSYSSTRR
Sequence length 611
Interactions View interactions