CUL4A (cullin 4A)

Gene

• Entrez ID: 8451
• Gene name: Cullin 4A
• Gene symbol: CUL4A
• Synonyms (NCBI Gene): -
• Chromosome: 13
• Chromosome location: 13q34
• Summary: CUL4A is the ubiquitin ligase component of a multimeric complex involved in the degradation of DNA damage-response proteins (Liu et al., 2009 [PubMed 19481525]).[supplied by OMIM, Oct 2009]

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT027107	hsa-miR-103a-3p	Sequencing	20371350
MIRT031821	hsa-miR-16-5p	Proteomics	18668040
MIRT050685	hsa-miR-18a-5p	CLASH	23622248
MIRT048313	hsa-miR-106a-5p	CLASH	23622248
MIRT046251	hsa-miR-23b-3p	CLASH	23622248
MIRT041473	hsa-miR-193b-3p	CLASH	23622248
MIRT039946	hsa-miR-615-3p	CLASH	23622248
MIRT723458	hsa-miR-4432	HITS-CLIP	19536157
MIRT723457	hsa-miR-451b	HITS-CLIP	19536157
MIRT723456	hsa-miR-4453	HITS-CLIP	19536157
MIRT723455	hsa-miR-4538	HITS-CLIP	19536157
MIRT248955	hsa-miR-6501-3p	HITS-CLIP	19536157
MIRT723454	hsa-miR-635	HITS-CLIP	19536157
MIRT723453	hsa-miR-6774-5p	HITS-CLIP	19536157
MIRT723452	hsa-miR-4696	HITS-CLIP	19536157
MIRT723451	hsa-miR-196a-3p	HITS-CLIP	19536157
MIRT731304	hsa-miR-9-5p	Luciferase reporter assay	26840256
MIRT731304	hsa-miR-9-5p	Luciferase reporter assay	26840256
MIRT731305	hsa-miR-137	Luciferase reporter assay	26840256
MIRT731305	hsa-miR-137	Luciferase reporter assay	26840256
MIRT731304	hsa-miR-9-5p	Immunofluorescence, Immunohistochemistry, Immunoprecipitaion, Luciferase reporter assay, qRT-PCR, Western blot	26840256
MIRT731304	hsa-miR-9-5p	Immunofluorescence, Immunohistochemistry, Immunoprecipitaion, Luciferase reporter assay, qRT-PCR, Western blot	26840256
MIRT731305	hsa-miR-137	Immunofluorescence, Immunohistochemistry, Immunoprecipitaion, Luciferase reporter assay, qRT-PCR, Western blot	26840256
MIRT731305	hsa-miR-137	Immunofluorescence, Immunohistochemistry, Immunoprecipitaion, Luciferase reporter assay, qRT-PCR, Western blot	26840256
MIRT723458	hsa-miR-4432	HITS-CLIP	19536157
MIRT723457	hsa-miR-451b	HITS-CLIP	19536157
MIRT723456	hsa-miR-4453	HITS-CLIP	19536157
MIRT723455	hsa-miR-4538	HITS-CLIP	19536157
MIRT248955	hsa-miR-6501-3p	HITS-CLIP	19536157
MIRT723454	hsa-miR-635	HITS-CLIP	19536157
MIRT723453	hsa-miR-6774-5p	HITS-CLIP	19536157
MIRT723452	hsa-miR-4696	HITS-CLIP	19536157
MIRT723451	hsa-miR-196a-3p	HITS-CLIP	19536157
MIRT755340	hsa-miR-665	Luciferase reporter assay, qRT-PCR, RNA pull down assay	37507642
MIRT755340	hsa-miR-665	Luciferase reporter assay, qRT-PCR, Flow cytometry, ELISA, RNA pull down assay	37507642
MIRT916567	hsa-miR-103a	CLIP-seq
MIRT916568	hsa-miR-107	CLIP-seq
MIRT916569	hsa-miR-1182	CLIP-seq
MIRT916570	hsa-miR-1266	CLIP-seq
MIRT916571	hsa-miR-1271	CLIP-seq
MIRT916572	hsa-miR-181a	CLIP-seq
MIRT916573	hsa-miR-181b	CLIP-seq
MIRT916574	hsa-miR-181c	CLIP-seq
MIRT916575	hsa-miR-181d	CLIP-seq
MIRT916576	hsa-miR-193a-5p	CLIP-seq
MIRT916577	hsa-miR-216a	CLIP-seq
MIRT916578	hsa-miR-25	CLIP-seq
MIRT916579	hsa-miR-3127-5p	CLIP-seq
MIRT916580	hsa-miR-3179	CLIP-seq
MIRT916581	hsa-miR-3194-3p	CLIP-seq
MIRT916582	hsa-miR-32	CLIP-seq
MIRT916583	hsa-miR-3200-5p	CLIP-seq
MIRT916584	hsa-miR-363	CLIP-seq
MIRT916585	hsa-miR-367	CLIP-seq
MIRT916586	hsa-miR-3670	CLIP-seq
MIRT916587	hsa-miR-371-5p	CLIP-seq
MIRT916588	hsa-miR-371b-5p	CLIP-seq
MIRT916589	hsa-miR-377	CLIP-seq
MIRT916590	hsa-miR-3921	CLIP-seq
MIRT916591	hsa-miR-3973	CLIP-seq
MIRT916592	hsa-miR-4255	CLIP-seq
MIRT916593	hsa-miR-4262	CLIP-seq
MIRT916594	hsa-miR-4270	CLIP-seq
MIRT916595	hsa-miR-4300	CLIP-seq
MIRT916596	hsa-miR-4303	CLIP-seq
MIRT916597	hsa-miR-433	CLIP-seq
MIRT916598	hsa-miR-4441	CLIP-seq
MIRT916599	hsa-miR-450b-5p	CLIP-seq
MIRT916600	hsa-miR-4518	CLIP-seq
MIRT916601	hsa-miR-4521	CLIP-seq
MIRT916602	hsa-miR-4639-3p	CLIP-seq
MIRT916603	hsa-miR-4649-3p	CLIP-seq
MIRT916604	hsa-miR-4653-5p	CLIP-seq
MIRT916605	hsa-miR-4705	CLIP-seq
MIRT916606	hsa-miR-4719	CLIP-seq
MIRT916607	hsa-miR-4728-3p	CLIP-seq
MIRT916608	hsa-miR-4795-3p	CLIP-seq
MIRT916609	hsa-miR-4797-5p	CLIP-seq
MIRT916610	hsa-miR-4799-5p	CLIP-seq
MIRT916611	hsa-miR-507	CLIP-seq
MIRT916612	hsa-miR-5096	CLIP-seq
MIRT916613	hsa-miR-520g	CLIP-seq
MIRT916614	hsa-miR-520h	CLIP-seq
MIRT916615	hsa-miR-557	CLIP-seq
MIRT916616	hsa-miR-610	CLIP-seq
MIRT916617	hsa-miR-626	CLIP-seq
MIRT916618	hsa-miR-802	CLIP-seq
MIRT916619	hsa-miR-920	CLIP-seq
MIRT916620	hsa-miR-92a	CLIP-seq
MIRT916621	hsa-miR-92b	CLIP-seq
MIRT916622	hsa-miR-96	CLIP-seq
MIRT916623	hsa-miR-1251	CLIP-seq
MIRT916624	hsa-miR-216b	CLIP-seq
MIRT916625	hsa-miR-3613-3p	CLIP-seq
MIRT916626	hsa-miR-3675-3p	CLIP-seq
MIRT916627	hsa-miR-3688-3p	CLIP-seq
MIRT916628	hsa-miR-4261	CLIP-seq
MIRT916629	hsa-miR-4305	CLIP-seq
MIRT916630	hsa-miR-4311	CLIP-seq
MIRT916631	hsa-miR-4633-5p	CLIP-seq
MIRT916632	hsa-miR-4659a-5p	CLIP-seq
MIRT916633	hsa-miR-4659b-5p	CLIP-seq
MIRT916634	hsa-miR-4704-5p	CLIP-seq
MIRT916635	hsa-miR-603	CLIP-seq
MIRT916636	hsa-miR-607	CLIP-seq
MIRT1971868	hsa-miR-1208	CLIP-seq
MIRT1971869	hsa-miR-1288	CLIP-seq
MIRT916572	hsa-miR-181a	CLIP-seq
MIRT916573	hsa-miR-181b	CLIP-seq
MIRT916574	hsa-miR-181c	CLIP-seq
MIRT916575	hsa-miR-181d	CLIP-seq
MIRT1971870	hsa-miR-2115	CLIP-seq
MIRT1971871	hsa-miR-218	CLIP-seq
MIRT1971872	hsa-miR-3074-5p	CLIP-seq
MIRT1971873	hsa-miR-3124-3p	CLIP-seq
MIRT1971874	hsa-miR-3184	CLIP-seq
MIRT916581	hsa-miR-3194-3p	CLIP-seq
MIRT1971875	hsa-miR-3199	CLIP-seq
MIRT1971876	hsa-miR-370	CLIP-seq
MIRT916589	hsa-miR-377	CLIP-seq
MIRT916590	hsa-miR-3921	CLIP-seq
MIRT1971877	hsa-miR-3934	CLIP-seq
MIRT1971878	hsa-miR-3978	CLIP-seq
MIRT1971879	hsa-miR-423-5p	CLIP-seq
MIRT916593	hsa-miR-4262	CLIP-seq
MIRT1971880	hsa-miR-4289	CLIP-seq
MIRT1971881	hsa-miR-4420	CLIP-seq
MIRT916603	hsa-miR-4649-3p	CLIP-seq
MIRT916604	hsa-miR-4653-5p	CLIP-seq
MIRT1971882	hsa-miR-4668-3p	CLIP-seq
MIRT1971883	hsa-miR-4714-3p	CLIP-seq
MIRT1971884	hsa-miR-4724-5p	CLIP-seq
MIRT1971885	hsa-miR-4731-3p	CLIP-seq
MIRT1971886	hsa-miR-4789-5p	CLIP-seq
MIRT1971887	hsa-miR-4801	CLIP-seq
MIRT1971888	hsa-miR-494	CLIP-seq
MIRT1971889	hsa-miR-500a	CLIP-seq
MIRT1971890	hsa-miR-501-5p	CLIP-seq
MIRT1971891	hsa-miR-513b	CLIP-seq
MIRT1971892	hsa-miR-516a-3p	CLIP-seq
MIRT1971893	hsa-miR-548aa	CLIP-seq
MIRT1971894	hsa-miR-552	CLIP-seq
MIRT1971895	hsa-miR-636	CLIP-seq
MIRT916567	hsa-miR-103a	CLIP-seq
MIRT916568	hsa-miR-107	CLIP-seq
MIRT916569	hsa-miR-1182	CLIP-seq
MIRT2207515	hsa-miR-1207-3p	CLIP-seq
MIRT1971868	hsa-miR-1208	CLIP-seq
MIRT2207516	hsa-miR-1264	CLIP-seq
MIRT2207517	hsa-miR-1301	CLIP-seq
MIRT916572	hsa-miR-181a	CLIP-seq
MIRT916573	hsa-miR-181b	CLIP-seq
MIRT916574	hsa-miR-181c	CLIP-seq
MIRT916575	hsa-miR-181d	CLIP-seq
MIRT916576	hsa-miR-193a-5p	CLIP-seq
MIRT2207518	hsa-miR-200b	CLIP-seq
MIRT2207519	hsa-miR-200c	CLIP-seq
MIRT1971870	hsa-miR-2115	CLIP-seq
MIRT2207520	hsa-miR-214	CLIP-seq
MIRT916577	hsa-miR-216a	CLIP-seq
MIRT1971871	hsa-miR-218	CLIP-seq
MIRT916578	hsa-miR-25	CLIP-seq
MIRT2207521	hsa-miR-3065-5p	CLIP-seq
MIRT1971872	hsa-miR-3074-5p	CLIP-seq
MIRT2207522	hsa-miR-3120-3p	CLIP-seq
MIRT2207523	hsa-miR-3141	CLIP-seq
MIRT916581	hsa-miR-3194-3p	CLIP-seq
MIRT916582	hsa-miR-32	CLIP-seq
MIRT2207524	hsa-miR-34c-3p	CLIP-seq
MIRT2207525	hsa-miR-3619-5p	CLIP-seq
MIRT916584	hsa-miR-363	CLIP-seq
MIRT2207526	hsa-miR-3655	CLIP-seq
MIRT916585	hsa-miR-367	CLIP-seq
MIRT1971876	hsa-miR-370	CLIP-seq
MIRT916587	hsa-miR-371-5p	CLIP-seq
MIRT916588	hsa-miR-371b-5p	CLIP-seq
MIRT916589	hsa-miR-377	CLIP-seq
MIRT2207527	hsa-miR-3919	CLIP-seq
MIRT916590	hsa-miR-3921	CLIP-seq
MIRT2207528	hsa-miR-3925-5p	CLIP-seq
MIRT1971877	hsa-miR-3934	CLIP-seq
MIRT916591	hsa-miR-3973	CLIP-seq
MIRT916593	hsa-miR-4262	CLIP-seq
MIRT916594	hsa-miR-4270	CLIP-seq
MIRT1971880	hsa-miR-4289	CLIP-seq
MIRT2207529	hsa-miR-429	CLIP-seq
MIRT916597	hsa-miR-433	CLIP-seq
MIRT1971881	hsa-miR-4420	CLIP-seq
MIRT916598	hsa-miR-4441	CLIP-seq
MIRT916601	hsa-miR-4521	CLIP-seq
MIRT2207530	hsa-miR-4539	CLIP-seq
MIRT916603	hsa-miR-4649-3p	CLIP-seq
MIRT916604	hsa-miR-4653-5p	CLIP-seq
MIRT2207531	hsa-miR-4660	CLIP-seq
MIRT1971882	hsa-miR-4668-3p	CLIP-seq
MIRT2207532	hsa-miR-4698	CLIP-seq
MIRT916605	hsa-miR-4705	CLIP-seq
MIRT1971883	hsa-miR-4714-3p	CLIP-seq
MIRT916606	hsa-miR-4719	CLIP-seq
MIRT1971884	hsa-miR-4724-5p	CLIP-seq
MIRT1971885	hsa-miR-4731-3p	CLIP-seq
MIRT2207533	hsa-miR-4753-3p	CLIP-seq
MIRT2207534	hsa-miR-4778-3p	CLIP-seq
MIRT1971886	hsa-miR-4789-5p	CLIP-seq
MIRT916608	hsa-miR-4795-3p	CLIP-seq
MIRT1971887	hsa-miR-4801	CLIP-seq
MIRT2207535	hsa-miR-495	CLIP-seq
MIRT2207536	hsa-miR-499-3p	CLIP-seq
MIRT2207537	hsa-miR-499a-3p	CLIP-seq
MIRT2207538	hsa-miR-5047	CLIP-seq
MIRT2207539	hsa-miR-512-5p	CLIP-seq
MIRT2207540	hsa-miR-514	CLIP-seq
MIRT2207541	hsa-miR-514b-3p	CLIP-seq
MIRT1971892	hsa-miR-516a-3p	CLIP-seq
MIRT916613	hsa-miR-520g	CLIP-seq
MIRT916614	hsa-miR-520h	CLIP-seq
MIRT1971893	hsa-miR-548aa	CLIP-seq
MIRT2207542	hsa-miR-548l	CLIP-seq
MIRT2207543	hsa-miR-548n	CLIP-seq
MIRT1971894	hsa-miR-552	CLIP-seq
MIRT2207544	hsa-miR-578	CLIP-seq
MIRT2207545	hsa-miR-582-5p	CLIP-seq
MIRT916616	hsa-miR-610	CLIP-seq
MIRT1971895	hsa-miR-636	CLIP-seq
MIRT2207546	hsa-miR-642b	CLIP-seq
MIRT2207547	hsa-miR-761	CLIP-seq
MIRT916618	hsa-miR-802	CLIP-seq
MIRT2207548	hsa-miR-922	CLIP-seq
MIRT916620	hsa-miR-92a	CLIP-seq
MIRT916621	hsa-miR-92b	CLIP-seq
MIRT2207549	hsa-miR-942	CLIP-seq
MIRT2510746	hsa-miR-1184	CLIP-seq
MIRT2510747	hsa-miR-1205	CLIP-seq
MIRT2207515	hsa-miR-1207-3p	CLIP-seq
MIRT2207516	hsa-miR-1264	CLIP-seq
MIRT2510748	hsa-miR-1287	CLIP-seq
MIRT2510749	hsa-miR-142-5p	CLIP-seq
MIRT916572	hsa-miR-181a	CLIP-seq
MIRT916573	hsa-miR-181b	CLIP-seq
MIRT916574	hsa-miR-181c	CLIP-seq
MIRT916575	hsa-miR-181d	CLIP-seq
MIRT1971870	hsa-miR-2115	CLIP-seq
MIRT2207520	hsa-miR-214	CLIP-seq
MIRT1971871	hsa-miR-218	CLIP-seq
MIRT1971872	hsa-miR-3074-5p	CLIP-seq
MIRT2510750	hsa-miR-3125	CLIP-seq
MIRT2510751	hsa-miR-3133	CLIP-seq
MIRT2207523	hsa-miR-3141	CLIP-seq
MIRT2510752	hsa-miR-3148	CLIP-seq
MIRT2510753	hsa-miR-3158-5p	CLIP-seq
MIRT916581	hsa-miR-3194-3p	CLIP-seq
MIRT2510754	hsa-miR-340	CLIP-seq
MIRT2510755	hsa-miR-3611	CLIP-seq
MIRT2510756	hsa-miR-3616-5p	CLIP-seq
MIRT2207525	hsa-miR-3619-5p	CLIP-seq
MIRT2510757	hsa-miR-3647-5p	CLIP-seq
MIRT2207526	hsa-miR-3655	CLIP-seq
MIRT2510758	hsa-miR-3665	CLIP-seq
MIRT2510759	hsa-miR-3667-3p	CLIP-seq
MIRT916627	hsa-miR-3688-3p	CLIP-seq
MIRT1971876	hsa-miR-370	CLIP-seq
MIRT2510760	hsa-miR-380	CLIP-seq
MIRT2510761	hsa-miR-3916	CLIP-seq
MIRT916590	hsa-miR-3921	CLIP-seq
MIRT2510762	hsa-miR-3924	CLIP-seq
MIRT1971877	hsa-miR-3934	CLIP-seq
MIRT2510763	hsa-miR-3943	CLIP-seq
MIRT916592	hsa-miR-4255	CLIP-seq
MIRT916628	hsa-miR-4261	CLIP-seq
MIRT916593	hsa-miR-4262	CLIP-seq
MIRT2510764	hsa-miR-4287	CLIP-seq
MIRT2510765	hsa-miR-4297	CLIP-seq
MIRT2510766	hsa-miR-4312	CLIP-seq
MIRT2510767	hsa-miR-4323	CLIP-seq
MIRT2510768	hsa-miR-4457	CLIP-seq
MIRT2510769	hsa-miR-4495	CLIP-seq
MIRT2510770	hsa-miR-4511	CLIP-seq
MIRT916603	hsa-miR-4649-3p	CLIP-seq
MIRT916604	hsa-miR-4653-5p	CLIP-seq
MIRT2510771	hsa-miR-4668-5p	CLIP-seq
MIRT2510772	hsa-miR-4685-3p	CLIP-seq
MIRT916634	hsa-miR-4704-5p	CLIP-seq
MIRT1971885	hsa-miR-4731-3p	CLIP-seq
MIRT2207533	hsa-miR-4753-3p	CLIP-seq
MIRT2510773	hsa-miR-4756-3p	CLIP-seq
MIRT2207534	hsa-miR-4778-3p	CLIP-seq
MIRT1971887	hsa-miR-4801	CLIP-seq
MIRT1971888	hsa-miR-494	CLIP-seq
MIRT2207539	hsa-miR-512-5p	CLIP-seq
MIRT1971891	hsa-miR-513b	CLIP-seq
MIRT1971892	hsa-miR-516a-3p	CLIP-seq
MIRT2510774	hsa-miR-526b	CLIP-seq
MIRT2510775	hsa-miR-548a-3p	CLIP-seq
MIRT2510776	hsa-miR-548a-5p	CLIP-seq
MIRT2510777	hsa-miR-548ab	CLIP-seq
MIRT2510778	hsa-miR-548ae	CLIP-seq
MIRT2510779	hsa-miR-548aj	CLIP-seq
MIRT2510780	hsa-miR-548ak	CLIP-seq
MIRT2510781	hsa-miR-548am	CLIP-seq
MIRT2510782	hsa-miR-548b-5p	CLIP-seq
MIRT2510783	hsa-miR-548c-5p	CLIP-seq
MIRT2510784	hsa-miR-548d-5p	CLIP-seq
MIRT2510785	hsa-miR-548e	CLIP-seq
MIRT2510786	hsa-miR-548f	CLIP-seq
MIRT2510787	hsa-miR-548h	CLIP-seq
MIRT2510788	hsa-miR-548i	CLIP-seq
MIRT2510789	hsa-miR-548j	CLIP-seq
MIRT2510790	hsa-miR-548k	CLIP-seq
MIRT2207542	hsa-miR-548l	CLIP-seq
MIRT2510791	hsa-miR-548w	CLIP-seq
MIRT2510792	hsa-miR-548x	CLIP-seq
MIRT2510793	hsa-miR-548y	CLIP-seq
MIRT1971894	hsa-miR-552	CLIP-seq
MIRT2510794	hsa-miR-559	CLIP-seq
MIRT2510795	hsa-miR-573	CLIP-seq
MIRT2207544	hsa-miR-578	CLIP-seq
MIRT916635	hsa-miR-603	CLIP-seq
MIRT1971895	hsa-miR-636	CLIP-seq
MIRT2207546	hsa-miR-642b	CLIP-seq
MIRT2510796	hsa-miR-657	CLIP-seq
MIRT755340	hsa-miR-665	CLIP-seq
MIRT2207547	hsa-miR-761	CLIP-seq
MIRT916618	hsa-miR-802	CLIP-seq
MIRT2510797	hsa-miR-877	CLIP-seq
MIRT2207549	hsa-miR-942	CLIP-seq
MIRT2510746	hsa-miR-1184	CLIP-seq
MIRT2510747	hsa-miR-1205	CLIP-seq
MIRT2207515	hsa-miR-1207-3p	CLIP-seq
MIRT2207516	hsa-miR-1264	CLIP-seq
MIRT2207520	hsa-miR-214	CLIP-seq
MIRT2510750	hsa-miR-3125	CLIP-seq
MIRT2510751	hsa-miR-3133	CLIP-seq
MIRT2207523	hsa-miR-3141	CLIP-seq
MIRT2510752	hsa-miR-3148	CLIP-seq
MIRT2510753	hsa-miR-3158-5p	CLIP-seq
MIRT2510756	hsa-miR-3616-5p	CLIP-seq
MIRT2207525	hsa-miR-3619-5p	CLIP-seq
MIRT2510757	hsa-miR-3647-5p	CLIP-seq
MIRT2510758	hsa-miR-3665	CLIP-seq
MIRT916627	hsa-miR-3688-3p	CLIP-seq
MIRT2510761	hsa-miR-3916	CLIP-seq
MIRT2510763	hsa-miR-3943	CLIP-seq
MIRT916628	hsa-miR-4261	CLIP-seq
MIRT2510767	hsa-miR-4323	CLIP-seq
MIRT2510768	hsa-miR-4457	CLIP-seq
MIRT2510770	hsa-miR-4511	CLIP-seq
MIRT2510771	hsa-miR-4668-5p	CLIP-seq
MIRT916634	hsa-miR-4704-5p	CLIP-seq
MIRT1971885	hsa-miR-4731-3p	CLIP-seq
MIRT2207533	hsa-miR-4753-3p	CLIP-seq
MIRT2510773	hsa-miR-4756-3p	CLIP-seq
MIRT1971887	hsa-miR-4801	CLIP-seq
MIRT2207539	hsa-miR-512-5p	CLIP-seq
MIRT1971891	hsa-miR-513b	CLIP-seq
MIRT2510775	hsa-miR-548a-3p	CLIP-seq
MIRT2510778	hsa-miR-548ae	CLIP-seq
MIRT2510779	hsa-miR-548aj	CLIP-seq
MIRT2510781	hsa-miR-548am	CLIP-seq
MIRT2510785	hsa-miR-548e	CLIP-seq
MIRT2510786	hsa-miR-548f	CLIP-seq
MIRT2510792	hsa-miR-548x	CLIP-seq
MIRT2510795	hsa-miR-573	CLIP-seq
MIRT916635	hsa-miR-603	CLIP-seq
MIRT2207546	hsa-miR-642b	CLIP-seq
MIRT2510796	hsa-miR-657	CLIP-seq
MIRT2207547	hsa-miR-761	CLIP-seq
MIRT2510797	hsa-miR-877	CLIP-seq
MIRT2207549	hsa-miR-942	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000082	Process	G1/S transition of mitotic cell cycle	TAS	8681378
GO:0001701	Process	In utero embryonic development	IEA
GO:0005515	Function	Protein binding	IPI	12504025, 12504026, 12609982, 14739464, 16473935, 16949367, 16964240, 17041588, 18775313, 19966799, 21113133, 21145461, 21778237, 22157821, 22466964, 22939624, 26496610, 26906416, 28514442, 30945288, 32814053, 33961781, 35271311
GO:0005634	Component	Nucleus	IC	22118460
GO:0005634	Component	Nucleus	IDA	10585395, 11027288
GO:0005634	Component	Nucleus	NAS	22118460
GO:0005654	Component	Nucleoplasm	TAS
GO:0005737	Component	Cytoplasm	IDA	34065512
GO:0006281	Process	DNA repair	IEA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IEA
GO:0006511	Process	Ubiquitin-dependent protein catabolic process	IEA
GO:0006974	Process	DNA damage response	EXP	22118460
GO:0006974	Process	DNA damage response	IBA
GO:0006974	Process	DNA damage response	IEA
GO:0007283	Process	Spermatogenesis	IDA	34065512
GO:0007283	Process	Spermatogenesis	IDA	34065512
GO:0008283	Process	Cell population proliferation	IEA
GO:0008284	Process	Positive regulation of cell population proliferation	IEA
GO:0016567	Process	Protein ubiquitination	IBA
GO:0016567	Process	Protein ubiquitination	IDA	26431207
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016567	Process	Protein ubiquitination	IMP	28437394
GO:0030097	Process	Hemopoiesis	IEA
GO:0030853	Process	Negative regulation of granulocyte differentiation	IEA
GO:0031461	Component	Cullin-RING ubiquitin ligase complex	IEA
GO:0031464	Component	Cul4A-RING E3 ubiquitin ligase complex	EXP	22118460
GO:0031464	Component	Cul4A-RING E3 ubiquitin ligase complex	IBA
GO:0031464	Component	Cul4A-RING E3 ubiquitin ligase complex	IDA	12732143, 14739464, 17085480, 18794347, 20129063, 20223979
GO:0031464	Component	Cul4A-RING E3 ubiquitin ligase complex	IEA
GO:0031625	Function	Ubiquitin protein ligase binding	IBA
GO:0031625	Function	Ubiquitin protein ligase binding	IDA	11027288, 20870715
GO:0031625	Function	Ubiquitin protein ligase binding	IEA
GO:0032502	Process	Developmental process	IEA
GO:0034644	Process	Cellular response to UV	EXP	22118460
GO:0034644	Process	Cellular response to UV	IEA
GO:0035019	Process	Somatic stem cell population maintenance	IEA
GO:0035279	Process	MiRNA-mediated gene silencing by mRNA destabilization	IDA	16289642
GO:0042110	Process	T cell activation	IDA	34065512
GO:0042110	Process	T cell activation	IDA	34065512
GO:0042254	Process	Ribosome biogenesis	IEA
GO:0042254	Process	Ribosome biogenesis	IMP	26711351
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IEA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IEA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IMP	14739464
GO:0045732	Process	Positive regulation of protein catabolic process	IDA	11027288, 16482215, 27626656
GO:0045732	Process	Positive regulation of protein catabolic process	IDA	11027288, 20870715
GO:0048511	Process	Rhythmic process	IEA
GO:0051246	Process	Regulation of protein metabolic process	IEA
GO:0051246	Process	Regulation of protein metabolic process	IEA
GO:0060337	Process	Type I interferon-mediated signaling pathway	IMP	23391734
GO:0061630	Function	Ubiquitin protein ligase activity	IDA	20870715
GO:0080008	Component	Cul4-RING E3 ubiquitin ligase complex	IDA	16949367, 18381890, 32355176, 34526721
GO:0097193	Process	Intrinsic apoptotic signaling pathway	TAS	8681378
GO:0097510	Process	Base-excision repair, AP site formation via deaminated base removal	IDA	18973764
GO:0140627	Process	Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	IDA	29779948, 31267705, 34065512
GO:0140627	Process	Ubiquitin-dependent protein catabolic process via the C-end degron rule pathway	IDA	34065512
GO:0160072	Function	Ubiquitin ligase complex scaffold activity	IDA	34065512
GO:1900087	Process	Positive regulation of G1/S transition of mitotic cell cycle	IEA
GO:2000001	Process	Regulation of DNA damage checkpoint	IEA
GO:2000819	Process	Regulation of nucleotide-excision repair	IEA

Other IDs

• MIM: 603137
• HGNC: 2554
• e!Ensembl: ENSG00000139842

Protein

• UniProt ID: Q13619
• Protein name: Cullin-4A (CUL-4A)
• Protein function: Core component of multiple cullin-RING-based E3 ubiquitin-protein ligase complexes which mediate the ubiquitination of target proteins (PubMed:14578910, PubMed:14739464, PubMed:15448697, PubMed:15548678, PubMed:15811626, PubMed:16678110, PubMed:
• PDB: 2HYE, 4A0K, 7OKQ, 7OPC, 7OPD, 8B3G, 8B3I
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00888	Cullin	63 → 660	Cullin family	Family
  PF10557	Cullin_Nedd8	691 → 751	Cullin protein neddylation domain	Domain

• Sequence:

  MADEAPRKGSFSALVGRTNGLTKPAALAAAPAKPGGAGGSKKLVIKNFRDRPRLPDNYTQ
  DTWRKLHEAVRAVQSSTSIRYNLEELYQAVENLCSHKVSPMLYKQLRQACEDHVQAQILP
  FREDSLDSVLFLKKINTCWQDHCRQMIMIRSIFLFLDRTYVLQNSTLPSIWDMGLELFRT
  HIISDKMVQSKTIDGILLLIERERSGEAVDRSLLRSLLGMLSDLQVYKDSFELKFLEETN
  CLYAAEGQRLMQEREVPEYLNHVSKRLEEEGDRVITYLDHSTQKPLIACVEKQLLGEHLT
  AILQKGLDHLLDENRVPDLAQMYQLFSRVRGGQQALLQHWSEYIKTFGTAIVINPEKDKD
  MVQDLLDFKDKVDHVIEVCFQKNERFVNLMKESFETFINKRPNKPAELIAKHVDSKLRAG
  NKEATDEELERTLDKIMILFRFIHGKDVFEAFYKKDLAKRLLVGKSASVDAEKSMLSKLK
  HECGAAFTSKLEGMFKDMELSKDIMVHFKQHMQNQSDSGPIDLTVNILTMGYWPTYTPME
  VHLTPEMIKLQEVFKAFYLGKHSGRKLQWQTTLGHAVLKAEFKEGKKEFQVSLFQTLVLL
  MFNEGDGFSFEEIKMATGIEDSELRRTLQSLACGKARVLIKSPKGKEVEDGDKFIFNGEF
  KHKLFRIKINQIQMKETVEEQVSTTERVFQDRQYQIDAAIVRIMKMRKTLGHNLLVSELY
  NQLKFPVKPGDLKKRIESLIDRDYMERDKDNPNQYHYVA

• Sequence length: 759

Pathways

KEGG:

Nucleotide excision repair
Ubiquitin mediated proteolysis
Human immunodeficiency virus 1 infection

Reactome:

Recognition of DNA damage by PCNA-containing replication complex
DNA Damage Recognition in GG-NER
Formation of Incision Complex in GG-NER
Dual Incision in GG-NER
Formation of TC-NER Pre-Incision Complex
Transcription-Coupled Nucleotide Excision Repair (TC-NER)
Dual incision in TC-NER
Gap-filling DNA repair synthesis and ligation in TC-NER
Neddylation