RAB11FIP4 (RAB11 family interacting protein 4)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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84440 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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RAB11 family interacting protein 4 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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RAB11FIP4 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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FIP4-Rab11, RAB11-FIP4 |
Chromosome
Chromosome number
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17 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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17q11.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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The protein encoded by this gene interacts with RAB11 and is thought to be involved in bringing recycling endosome membranes to the cleavage furrow in late cytokinesis. Hypoxic conditions can lead to an upregulation of the encoded protein and enhance the |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q86YS3 | ||||||||||
Protein name | Rab11 family-interacting protein 4 (FIP4-Rab11) (Rab11-FIP4) (Arfophilin-2) | ||||||||||
Protein function | Acts as a regulator of endocytic traffic by participating in membrane delivery. Required for the abscission step in cytokinesis, possibly by acting as an 'address tag' delivering recycling endosome membranes to the cleavage furrow during late cy | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Present at high level in testis (at protein level). Weakly expressed in other tissues. {ECO:0000269|PubMed:12857874}. | ||||||||||
Sequence |
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Sequence length | 637 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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