Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID	8434
Gene name	Reversion inducing cysteine rich protein with kazal motifs
Gene symbol	RECK
Synonyms (NCBI Gene)	ST15
Chromosome	9
Chromosome location	9p13.3
Summary	The protein encoded by this gene is a cysteine-rich, extracellular protein with protease inhibitor-like domains whose expression is suppressed strongly in many tumors and cells transformed by various kinds of oncogenes. In normal cells, this membrane-anch

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miRTarBase ID	miRNA	Experiments	Reference
MIRT000969	hsa-miR-21-5p	qRT-PCRLuciferase reporter assayWestern blot	18794849
MIRT000969	hsa-miR-21-5p	qRT-PCRLuciferase reporter assayWestern blot	18794849
MIRT000969	hsa-miR-21-5p	Western blot	18591254
MIRT000969	hsa-miR-21-5p	qRT-PCR	18591254
MIRT000969	hsa-miR-21-5p	Luciferase reporter assay	18591254
MIRT000969	hsa-miR-21-5p	Luciferase reporter assay	18591254
MIRT000969	hsa-miR-21-5p	Review	19935707
MIRT000607	hsa-miR-15b-5p	Western blotqRT-PCRLuciferase reporter assay	20154725
MIRT000969	hsa-miR-21-5p	Western blotqRT-PCRLuciferase reporter assay	20154725
MIRT000606	hsa-miR-373-3p	Western blotqRT-PCRLuciferase reporter assay	20154725
MIRT000969	hsa-miR-21-5p	Luciferase reporter assay	18591254
MIRT000969	hsa-miR-21-5p	Luciferase reporter assayqRT-PCRWestern blot	20480266
MIRT000969	hsa-miR-21-5p	Luciferase reporter assayqRT-PCRWestern blot	20480266
MIRT006728	hsa-miR-222-3p	Luciferase reporter assay	22321642
MIRT006728	hsa-miR-222-3p	Luciferase reporter assay	22321642
MIRT000969	hsa-miR-21-5p	5.0	22630347
MIRT007090	hsa-miR-15a-5p	GFP reporter assayqRT-PCR	23176145
MIRT007090	hsa-miR-15a-5p	GFP reporter assayqRT-PCR	23176145
MIRT007293	hsa-miR-182-5p	Luciferase reporter assayqRT-PCRWestern blot	23333633
MIRT007293	hsa-miR-182-5p	Luciferase reporter assayqRT-PCRWestern blot	23333633
MIRT007293	hsa-miR-182-5p	Luciferase reporter assayqRT-PCRWestern blot	23333633
MIRT007293	hsa-miR-182-5p	Luciferase reporter assay	23226455
MIRT007293	hsa-miR-182-5p	Luciferase reporter assay	23383207
MIRT018129	hsa-miR-335-5p	Microarray	18185580
MIRT022764	hsa-miR-124-3p	Microarray	18668037
MIRT027078	hsa-miR-103a-3p	Sequencing	20371350
MIRT000969	hsa-miR-21-5p	Reporter assay;Western blot;Other	18794849
MIRT000969	hsa-miR-21-5p	Reporter assay;Western blot;qRT-PCR;Microarray	18591254
MIRT031373	hsa-miR-16-5p	Sequencing	20371350
MIRT031373	hsa-miR-16-5p	Luciferase reporter assayqRT-PCRWestern blot	24852767
MIRT031373	hsa-miR-16-5p	Luciferase reporter assayqRT-PCRWestern blot	24852767
MIRT000969	hsa-miR-21-5p	Luciferase reporter assayWestern blot	23504349
MIRT053577	hsa-miR-25-3p	Luciferase reporter assayqRT-PCRWestern blot	24078004
MIRT053577	hsa-miR-25-3p	Luciferase reporter assayqRT-PCRWestern blot	24078004
MIRT054260	hsa-miR-374b-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	25516656
MIRT054260	hsa-miR-374b-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	25516656
MIRT054260	hsa-miR-374b-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	25516656
MIRT054260	hsa-miR-374b-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	25516656
MIRT054260	hsa-miR-374b-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	25516656
MIRT054260	hsa-miR-374b-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	25516656
MIRT000969	hsa-miR-21-5p	qRT-PCRWestern blot	24594117
MIRT000969	hsa-miR-21-5p	Luciferase reporter assayWestern blot	23708209
MIRT438699	rno-miR-200c-3p	qRT-PCRWestern blot	24647918
MIRT438699	rno-miR-200c-3p	qRT-PCRWestern blot	24647918
MIRT438481	hsa-miR-92b-3p	Luciferase reporter assay	24162673
MIRT438481	hsa-miR-92b-3p	Luciferase reporter assay	24162673
MIRT000969	hsa-miR-21-5p	ImmunofluorescenceImmunohistochemistryqRT-PCRWestern blot	23811941
MIRT438045	hsa-miR-96-5p	Luciferase reporter assayqRT-PCRWestern blot	24366472
MIRT438045	hsa-miR-96-5p	Luciferase reporter assayqRT-PCRWestern blot	24366472
MIRT438699	rno-miR-200c-3p	qRT-PCRWestern blot	24647918
MIRT438699	rno-miR-200c-3p	qRT-PCRWestern blot	24647918
MIRT438481	hsa-miR-92b-3p	Luciferase reporter assay	24162673
MIRT438481	hsa-miR-92b-3p	Luciferase reporter assay	24162673
MIRT000969	hsa-miR-21-5p	ImmunofluorescenceImmunohistochemistryqRT-PCRWestern blot	23811941
MIRT438045	hsa-miR-96-5p	Luciferase reporter assayqRT-PCRWestern blot	24366472
MIRT438045	hsa-miR-96-5p	Luciferase reporter assayqRT-PCRWestern blot	24366472
MIRT031373	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT107688	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT107690	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT000607	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT007090	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT107689	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT107699	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT554845	hsa-miR-503-5p	PAR-CLIP	21572407
MIRT007293	hsa-miR-182-5p	PAR-CLIP	21572407
MIRT554844	hsa-miR-548ac	PAR-CLIP	21572407
MIRT554843	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT554842	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT554841	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT554840	hsa-miR-548z	PAR-CLIP	21572407
MIRT554839	hsa-miR-548ae-3p	PAR-CLIP	21572407
MIRT554838	hsa-miR-548ah-3p	PAR-CLIP	21572407
MIRT554837	hsa-miR-548aj-3p	PAR-CLIP	21572407
MIRT554836	hsa-miR-548am-3p	PAR-CLIP	21572407
MIRT554835	hsa-miR-548aq-3p	PAR-CLIP	21572407
MIRT554834	hsa-miR-548j-3p	PAR-CLIP	21572407
MIRT554833	hsa-miR-548x-3p	PAR-CLIP	21572407
MIRT554832	hsa-miR-618	PAR-CLIP	21572407
MIRT107692	hsa-miR-562	PAR-CLIP	21572407
MIRT554831	hsa-miR-646	PAR-CLIP	21572407
MIRT554830	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT554829	hsa-miR-299-5p	PAR-CLIP	21572407
MIRT107696	hsa-miR-4524a-5p	PAR-CLIP	21572407
MIRT107698	hsa-miR-4524b-5p	PAR-CLIP	21572407
MIRT554828	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT554827	hsa-miR-29b-2-5p	PAR-CLIP	21572407
MIRT554826	hsa-miR-1271-5p	PAR-CLIP	21572407
MIRT438045	hsa-miR-96-5p	PAR-CLIP	21572407
MIRT454996	hsa-miR-3714	PAR-CLIP	23592263
MIRT454995	hsa-miR-5586-3p	PAR-CLIP	23592263
MIRT454994	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT454993	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT454992	hsa-miR-940	PAR-CLIP	23592263
MIRT454991	hsa-miR-3922-5p	PAR-CLIP	23592263
MIRT454990	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT454989	hsa-miR-4693-3p	PAR-CLIP	23592263
MIRT454988	hsa-miR-7854-3p	PAR-CLIP	23592263
MIRT454987	hsa-miR-6134	PAR-CLIP	23592263
MIRT454986	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT454985	hsa-miR-5192	PAR-CLIP	23592263
MIRT454984	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT454982	hsa-miR-7154-3p	PAR-CLIP	23592263
MIRT454983	hsa-miR-765	PAR-CLIP	23592263
MIRT454981	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT454980	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT454979	hsa-miR-1294	PAR-CLIP	23592263
MIRT454978	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT731169	hsa-miR-135b-5p	Western blotLuciferase reporter assay	25537516
MIRT731169	hsa-miR-135b-5p	Western blotLuciferase reporter assay	25537516
MIRT731853	hsa-miR-15b-3p	Western blot	27530410
MIRT731853	hsa-miR-15b-3p	Western blot	27530410
MIRT054649	hsa-miR-221-3p	FlowLuciferase reporter assayqRT-PCRWestern blot	26364844
MIRT054649	hsa-miR-221-3p	FlowLuciferase reporter assayqRT-PCRWestern blot	26364844
MIRT006728	hsa-miR-222-3p	FlowLuciferase reporter assayqRT-PCRWestern blot	26364844
MIRT006728	hsa-miR-222-3p	FlowLuciferase reporter assayqRT-PCRWestern blot	26364844
MIRT731975	hsa-miR-409-3p	Luciferase reporter assay	27158382
MIRT731975	hsa-miR-409-3p	Luciferase reporter assay	27158382
MIRT000969	hsa-miR-21-5p	qRT-PCRWestern blot	26741162
MIRT007293	hsa-miR-182-5p	qRT-PCRWestern blot	26609496
MIRT438045	hsa-miR-96-5p	qRT-PCRWestern blot	26609496
MIRT438481	hsa-miR-92b-3p	Luciferase reporter assay	26993249
MIRT438481	hsa-miR-92b-3p	Luciferase reporter assay	26993249
MIRT438481	hsa-miR-92b-3p	Luciferase reporter assay	26993249
MIRT438481	hsa-miR-92b-3p	Luciferase reporter assay	26993249
MIRT438481	hsa-miR-92b-3p	5.0	26993249
MIRT438481	hsa-miR-92b-3p	5.0	26993249
MIRT438481	hsa-miR-92b-3p	5.0	26993249
MIRT438481	hsa-miR-92b-3p	5.0	26993249
MIRT736966	hsa-miR-145-5p	ChIP-seqqRT-PCR	32221048
MIRT031373	hsa-miR-16-5p	PAR-CLIP	21572407
MIRT107688	hsa-miR-195-5p	PAR-CLIP	21572407
MIRT107690	hsa-miR-497-5p	PAR-CLIP	21572407
MIRT000607	hsa-miR-15b-5p	PAR-CLIP	21572407
MIRT007090	hsa-miR-15a-5p	PAR-CLIP	21572407
MIRT107689	hsa-miR-424-5p	PAR-CLIP	21572407
MIRT107699	hsa-miR-6838-5p	PAR-CLIP	21572407
MIRT554845	hsa-miR-503-5p	PAR-CLIP	21572407
MIRT007293	hsa-miR-182-5p	PAR-CLIP	21572407
MIRT554844	hsa-miR-548ac	PAR-CLIP	21572407
MIRT554843	hsa-miR-548bb-3p	PAR-CLIP	21572407
MIRT554842	hsa-miR-548d-3p	PAR-CLIP	21572407
MIRT554841	hsa-miR-548h-3p	PAR-CLIP	21572407
MIRT554840	hsa-miR-548z	PAR-CLIP	21572407
MIRT554839	hsa-miR-548ae-3p	PAR-CLIP	21572407
MIRT554838	hsa-miR-548ah-3p	PAR-CLIP	21572407
MIRT554837	hsa-miR-548aj-3p	PAR-CLIP	21572407
MIRT554836	hsa-miR-548am-3p	PAR-CLIP	21572407
MIRT554835	hsa-miR-548aq-3p	PAR-CLIP	21572407
MIRT554834	hsa-miR-548j-3p	PAR-CLIP	21572407
MIRT554833	hsa-miR-548x-3p	PAR-CLIP	21572407
MIRT554832	hsa-miR-618	PAR-CLIP	21572407
MIRT107692	hsa-miR-562	PAR-CLIP	21572407
MIRT554831	hsa-miR-646	PAR-CLIP	21572407
MIRT554830	hsa-miR-410-3p	PAR-CLIP	21572407
MIRT554829	hsa-miR-299-5p	PAR-CLIP	21572407
MIRT107696	hsa-miR-4524a-5p	PAR-CLIP	21572407
MIRT107698	hsa-miR-4524b-5p	PAR-CLIP	21572407
MIRT554828	hsa-miR-190a-3p	PAR-CLIP	21572407
MIRT554827	hsa-miR-29b-2-5p	PAR-CLIP	21572407
MIRT554826	hsa-miR-1271-5p	PAR-CLIP	21572407
MIRT438045	hsa-miR-96-5p	PAR-CLIP	21572407
MIRT454996	hsa-miR-3714	PAR-CLIP	23592263
MIRT454995	hsa-miR-5586-3p	PAR-CLIP	23592263
MIRT454994	hsa-miR-6808-5p	PAR-CLIP	23592263
MIRT454993	hsa-miR-6893-5p	PAR-CLIP	23592263
MIRT454992	hsa-miR-940	PAR-CLIP	23592263
MIRT454991	hsa-miR-3922-5p	PAR-CLIP	23592263
MIRT454990	hsa-miR-4768-3p	PAR-CLIP	23592263
MIRT454989	hsa-miR-4693-3p	PAR-CLIP	23592263
MIRT454988	hsa-miR-7854-3p	PAR-CLIP	23592263
MIRT454987	hsa-miR-6134	PAR-CLIP	23592263
MIRT454986	hsa-miR-4722-5p	PAR-CLIP	23592263
MIRT454985	hsa-miR-5192	PAR-CLIP	23592263
MIRT454984	hsa-miR-766-5p	PAR-CLIP	23592263
MIRT454982	hsa-miR-7154-3p	PAR-CLIP	23592263
MIRT454983	hsa-miR-765	PAR-CLIP	23592263
MIRT454981	hsa-miR-6894-5p	PAR-CLIP	23592263
MIRT454980	hsa-miR-6880-5p	PAR-CLIP	23592263
MIRT454979	hsa-miR-1294	PAR-CLIP	23592263
MIRT454978	hsa-miR-7847-3p	PAR-CLIP	23592263
MIRT1299234	hsa-miR-329	CLIP-seq
MIRT1299235	hsa-miR-362-3p	CLIP-seq
MIRT1299236	hsa-miR-3671	CLIP-seq
MIRT1299237	hsa-miR-369-3p	CLIP-seq
MIRT1299238	hsa-miR-374a	CLIP-seq
MIRT1299239	hsa-miR-374b	CLIP-seq
MIRT1299240	hsa-miR-3941	CLIP-seq
MIRT1299241	hsa-miR-4291	CLIP-seq
MIRT1299242	hsa-miR-4696	CLIP-seq
MIRT1299243	hsa-miR-4731-3p	CLIP-seq
MIRT1299244	hsa-miR-4801	CLIP-seq
MIRT1299245	hsa-miR-499-3p	CLIP-seq
MIRT1299246	hsa-miR-499a-3p	CLIP-seq
MIRT1299247	hsa-miR-545	CLIP-seq
MIRT1299248	hsa-miR-603	CLIP-seq
MIRT1299249	hsa-miR-607	CLIP-seq
MIRT1553056	hsa-miR-1271	CLIP-seq
MIRT1553057	hsa-miR-15a	CLIP-seq
MIRT1553058	hsa-miR-15b	CLIP-seq
MIRT1553059	hsa-miR-16	CLIP-seq
MIRT1553060	hsa-miR-182	CLIP-seq
MIRT1553061	hsa-miR-195	CLIP-seq
MIRT1553062	hsa-miR-21	CLIP-seq
MIRT1299236	hsa-miR-3671	CLIP-seq
MIRT1553063	hsa-miR-410	CLIP-seq
MIRT1553064	hsa-miR-424	CLIP-seq
MIRT1553065	hsa-miR-4524	CLIP-seq
MIRT1553066	hsa-miR-4719	CLIP-seq
MIRT1553067	hsa-miR-494	CLIP-seq
MIRT1553068	hsa-miR-497	CLIP-seq
MIRT1553069	hsa-miR-503	CLIP-seq
MIRT1553070	hsa-miR-548g	CLIP-seq
MIRT1299249	hsa-miR-607	CLIP-seq
MIRT1553071	hsa-miR-96	CLIP-seq
MIRT1553056	hsa-miR-1271	CLIP-seq
MIRT1553060	hsa-miR-182	CLIP-seq
MIRT1553071	hsa-miR-96	CLIP-seq
MIRT2089067	hsa-miR-3613-3p	CLIP-seq
MIRT1553066	hsa-miR-4719	CLIP-seq
MIRT2089068	hsa-miR-5096	CLIP-seq
MIRT2313897	hsa-miR-4272	CLIP-seq
MIRT2432584	hsa-miR-1206	CLIP-seq
MIRT2432585	hsa-miR-1248	CLIP-seq
MIRT2432586	hsa-miR-1255a	CLIP-seq
MIRT2432587	hsa-miR-1255b	CLIP-seq
MIRT1553056	hsa-miR-1271	CLIP-seq
MIRT2432588	hsa-miR-1283	CLIP-seq
MIRT2432589	hsa-miR-1305	CLIP-seq
MIRT2432590	hsa-miR-1324	CLIP-seq
MIRT2432591	hsa-miR-135a	CLIP-seq
MIRT2432592	hsa-miR-135b	CLIP-seq
MIRT1553057	hsa-miR-15a	CLIP-seq
MIRT1553058	hsa-miR-15b	CLIP-seq
MIRT1553059	hsa-miR-16	CLIP-seq
MIRT2432593	hsa-miR-181a	CLIP-seq
MIRT2432594	hsa-miR-181b	CLIP-seq
MIRT2432595	hsa-miR-181c	CLIP-seq
MIRT2432596	hsa-miR-181d	CLIP-seq
MIRT1553060	hsa-miR-182	CLIP-seq
MIRT2432597	hsa-miR-188-5p	CLIP-seq
MIRT2432598	hsa-miR-1910	CLIP-seq
MIRT1553061	hsa-miR-195	CLIP-seq
MIRT2432599	hsa-miR-200b	CLIP-seq
MIRT2432600	hsa-miR-200c	CLIP-seq
MIRT1553062	hsa-miR-21	CLIP-seq
MIRT2432601	hsa-miR-219-5p	CLIP-seq
MIRT2432602	hsa-miR-302a	CLIP-seq
MIRT2432603	hsa-miR-302b	CLIP-seq
MIRT2432604	hsa-miR-302c	CLIP-seq
MIRT2432605	hsa-miR-302d	CLIP-seq
MIRT2432606	hsa-miR-302e	CLIP-seq
MIRT2432607	hsa-miR-3074-3p	CLIP-seq
MIRT2432608	hsa-miR-3117-5p	CLIP-seq
MIRT2432609	hsa-miR-3121-3p	CLIP-seq
MIRT2432610	hsa-miR-3126-3p	CLIP-seq
MIRT2432611	hsa-miR-3140-5p	CLIP-seq
MIRT2432612	hsa-miR-3163	CLIP-seq
MIRT1299234	hsa-miR-329	CLIP-seq
MIRT2432613	hsa-miR-3607-5p	CLIP-seq
MIRT1299235	hsa-miR-362-3p	CLIP-seq
MIRT1299236	hsa-miR-3671	CLIP-seq
MIRT2432614	hsa-miR-3682-5p	CLIP-seq
MIRT2432615	hsa-miR-3688-3p	CLIP-seq
MIRT1299237	hsa-miR-369-3p	CLIP-seq
MIRT2432616	hsa-miR-371b-3p	CLIP-seq
MIRT2432617	hsa-miR-372	CLIP-seq
MIRT2432618	hsa-miR-373	CLIP-seq
MIRT1299238	hsa-miR-374a	CLIP-seq
MIRT1299239	hsa-miR-374b	CLIP-seq
MIRT2432619	hsa-miR-374c	CLIP-seq
MIRT2432620	hsa-miR-3924	CLIP-seq
MIRT1299240	hsa-miR-3941	CLIP-seq
MIRT2432621	hsa-miR-3942-3p	CLIP-seq
MIRT2432622	hsa-miR-3973	CLIP-seq
MIRT2432623	hsa-miR-3978	CLIP-seq
MIRT1553063	hsa-miR-410	CLIP-seq
MIRT1553064	hsa-miR-424	CLIP-seq
MIRT2432624	hsa-miR-4257	CLIP-seq
MIRT2432625	hsa-miR-4262	CLIP-seq
MIRT2313897	hsa-miR-4272	CLIP-seq
MIRT2432626	hsa-miR-4274	CLIP-seq
MIRT2432627	hsa-miR-4289	CLIP-seq
MIRT2432628	hsa-miR-429	CLIP-seq
MIRT1299241	hsa-miR-4291	CLIP-seq
MIRT2432629	hsa-miR-4445	CLIP-seq
MIRT2432630	hsa-miR-448	CLIP-seq
MIRT2432631	hsa-miR-4495	CLIP-seq
MIRT1553065	hsa-miR-4524	CLIP-seq
MIRT2432632	hsa-miR-4530	CLIP-seq
MIRT2432633	hsa-miR-4641	CLIP-seq
MIRT2432634	hsa-miR-4643	CLIP-seq
MIRT2432635	hsa-miR-466	CLIP-seq
MIRT2432636	hsa-miR-4666-5p	CLIP-seq
MIRT2432637	hsa-miR-4668-3p	CLIP-seq
MIRT2432638	hsa-miR-4699-3p	CLIP-seq
MIRT1553066	hsa-miR-4719	CLIP-seq
MIRT2432639	hsa-miR-4729	CLIP-seq
MIRT1299243	hsa-miR-4731-3p	CLIP-seq
MIRT2432640	hsa-miR-4766-5p	CLIP-seq
MIRT2432641	hsa-miR-4778-3p	CLIP-seq
MIRT2432642	hsa-miR-4778-5p	CLIP-seq
MIRT2432643	hsa-miR-4782-3p	CLIP-seq
MIRT2432644	hsa-miR-4789-3p	CLIP-seq
MIRT2432645	hsa-miR-4795-3p	CLIP-seq
MIRT1299244	hsa-miR-4801	CLIP-seq
MIRT1553067	hsa-miR-494	CLIP-seq
MIRT1553068	hsa-miR-497	CLIP-seq
MIRT2432646	hsa-miR-498	CLIP-seq
MIRT1299245	hsa-miR-499-3p	CLIP-seq
MIRT1299246	hsa-miR-499a-3p	CLIP-seq
MIRT1553069	hsa-miR-503	CLIP-seq
MIRT2432647	hsa-miR-508-3p	CLIP-seq
MIRT2089068	hsa-miR-5096	CLIP-seq
MIRT2432648	hsa-miR-510	CLIP-seq
MIRT2432649	hsa-miR-511	CLIP-seq
MIRT2432650	hsa-miR-512-5p	CLIP-seq
MIRT2432651	hsa-miR-519a	CLIP-seq
MIRT2432652	hsa-miR-519b-3p	CLIP-seq
MIRT2432653	hsa-miR-519c-3p	CLIP-seq
MIRT2432654	hsa-miR-520a-3p	CLIP-seq
MIRT2432655	hsa-miR-520b	CLIP-seq
MIRT2432656	hsa-miR-520c-3p	CLIP-seq
MIRT2432657	hsa-miR-520d-3p	CLIP-seq
MIRT2432658	hsa-miR-520d-5p	CLIP-seq
MIRT2432659	hsa-miR-520e	CLIP-seq
MIRT2432660	hsa-miR-520g	CLIP-seq
MIRT2432661	hsa-miR-520h	CLIP-seq
MIRT2432662	hsa-miR-524-5p	CLIP-seq
MIRT1299247	hsa-miR-545	CLIP-seq
MIRT2432663	hsa-miR-548ae	CLIP-seq
MIRT2432664	hsa-miR-548aj	CLIP-seq
MIRT2432665	hsa-miR-548am	CLIP-seq
MIRT1553070	hsa-miR-548g	CLIP-seq
MIRT2432666	hsa-miR-548l	CLIP-seq
MIRT2432667	hsa-miR-548x	CLIP-seq
MIRT1299248	hsa-miR-603	CLIP-seq
MIRT1299249	hsa-miR-607	CLIP-seq
MIRT2432668	hsa-miR-616	CLIP-seq
MIRT2432669	hsa-miR-634	CLIP-seq
MIRT2432670	hsa-miR-655	CLIP-seq
MIRT2432671	hsa-miR-889	CLIP-seq
MIRT2432672	hsa-miR-890	CLIP-seq
MIRT2432673	hsa-miR-944	CLIP-seq
MIRT1553071	hsa-miR-96	CLIP-seq
MIRT1553066	hsa-miR-4719	CLIP-seq
MIRT2432590	hsa-miR-1324	CLIP-seq
MIRT2432597	hsa-miR-188-5p	CLIP-seq
MIRT2432602	hsa-miR-302a	CLIP-seq
MIRT2432603	hsa-miR-302b	CLIP-seq
MIRT2432604	hsa-miR-302c	CLIP-seq
MIRT2432605	hsa-miR-302d	CLIP-seq
MIRT2432606	hsa-miR-302e	CLIP-seq
MIRT2432607	hsa-miR-3074-3p	CLIP-seq
MIRT2432608	hsa-miR-3117-5p	CLIP-seq
MIRT2089067	hsa-miR-3613-3p	CLIP-seq
MIRT2610476	hsa-miR-3659	CLIP-seq
MIRT2432614	hsa-miR-3682-5p	CLIP-seq
MIRT1299237	hsa-miR-369-3p	CLIP-seq
MIRT2432616	hsa-miR-371b-3p	CLIP-seq
MIRT2432617	hsa-miR-372	CLIP-seq
MIRT2432618	hsa-miR-373	CLIP-seq
MIRT1299238	hsa-miR-374a	CLIP-seq
MIRT1299239	hsa-miR-374b	CLIP-seq
MIRT2432620	hsa-miR-3924	CLIP-seq
MIRT1553063	hsa-miR-410	CLIP-seq
MIRT1299241	hsa-miR-4291	CLIP-seq
MIRT2432633	hsa-miR-4641	CLIP-seq
MIRT2610477	hsa-miR-4658	CLIP-seq
MIRT1553066	hsa-miR-4719	CLIP-seq
MIRT2432639	hsa-miR-4729	CLIP-seq
MIRT2432640	hsa-miR-4766-5p	CLIP-seq
MIRT2432642	hsa-miR-4778-5p	CLIP-seq
MIRT2432651	hsa-miR-519a	CLIP-seq
MIRT2432652	hsa-miR-519b-3p	CLIP-seq
MIRT2432653	hsa-miR-519c-3p	CLIP-seq
MIRT2432654	hsa-miR-520a-3p	CLIP-seq
MIRT2432655	hsa-miR-520b	CLIP-seq
MIRT2432656	hsa-miR-520c-3p	CLIP-seq
MIRT2432657	hsa-miR-520d-3p	CLIP-seq
MIRT2432659	hsa-miR-520e	CLIP-seq
MIRT1299247	hsa-miR-545	CLIP-seq
MIRT2610478	hsa-miR-574-5p	CLIP-seq
MIRT2432668	hsa-miR-616	CLIP-seq
MIRT2432673	hsa-miR-944	CLIP-seq
MIRT2689635	hsa-miR-153	CLIP-seq
MIRT2432602	hsa-miR-302a	CLIP-seq
MIRT2432603	hsa-miR-302b	CLIP-seq
MIRT2432604	hsa-miR-302c	CLIP-seq
MIRT2432605	hsa-miR-302d	CLIP-seq
MIRT2432606	hsa-miR-302e	CLIP-seq
MIRT2432608	hsa-miR-3117-5p	CLIP-seq
MIRT2689636	hsa-miR-3140-3p	CLIP-seq
MIRT2610476	hsa-miR-3659	CLIP-seq
MIRT2432616	hsa-miR-371b-3p	CLIP-seq
MIRT2432617	hsa-miR-372	CLIP-seq
MIRT2432618	hsa-miR-373	CLIP-seq
MIRT1553063	hsa-miR-410	CLIP-seq
MIRT1299241	hsa-miR-4291	CLIP-seq
MIRT2432630	hsa-miR-448	CLIP-seq
MIRT2689637	hsa-miR-450b-5p	CLIP-seq
MIRT2432633	hsa-miR-4641	CLIP-seq
MIRT2610477	hsa-miR-4658	CLIP-seq
MIRT1553066	hsa-miR-4719	CLIP-seq
MIRT2432639	hsa-miR-4729	CLIP-seq
MIRT2432640	hsa-miR-4766-5p	CLIP-seq
MIRT2432642	hsa-miR-4778-5p	CLIP-seq
MIRT2689638	hsa-miR-507	CLIP-seq
MIRT2432651	hsa-miR-519a	CLIP-seq
MIRT2432652	hsa-miR-519b-3p	CLIP-seq
MIRT2432653	hsa-miR-519c-3p	CLIP-seq
MIRT2432654	hsa-miR-520a-3p	CLIP-seq
MIRT2432655	hsa-miR-520b	CLIP-seq
MIRT2432656	hsa-miR-520c-3p	CLIP-seq
MIRT2432657	hsa-miR-520d-3p	CLIP-seq
MIRT2432659	hsa-miR-520e	CLIP-seq
MIRT1299247	hsa-miR-545	CLIP-seq
MIRT2689639	hsa-miR-557	CLIP-seq
MIRT2610478	hsa-miR-574-5p	CLIP-seq
MIRT2432668	hsa-miR-616	CLIP-seq
MIRT2432673	hsa-miR-944	CLIP-seq

Show/Hide all (8)

Transcription factor	Regulation	Reference
HDAC1	Activation	20442303
HDAC1	Repression	20442303
HDAC1	Unknown	16377629
HDAC4	Unknown	22781396
HIF1A	Repression	20442303
SP1	Activation	17828469
SP1	Unknown	16377629
SP3	Unknown	16377629

Show/Hide all (37)

GO ID	Ontology	Definition	Evidence	Reference
GO:0001955	Process	Blood vessel maturation	IBA
GO:0001955	Process	Blood vessel maturation	IEA
GO:0002040	Process	Sprouting angiogenesis	IBA
GO:0004866	Function	Endopeptidase inhibitor activity	IBA
GO:0004866	Function	Endopeptidase inhibitor activity	IDA	9789069
GO:0004866	Function	Endopeptidase inhibitor activity	IEA
GO:0004867	Function	Serine-type endopeptidase inhibitor activity	IEA
GO:0005515	Function	Protein binding	IPI	21255571
GO:0005576	Component	Extracellular region	TAS
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IDA
GO:0005886	Component	Plasma membrane	IEA
GO:0005886	Component	Plasma membrane	TAS
GO:0007566	Process	Embryo implantation	IEA
GO:0008191	Function	Metalloendopeptidase inhibitor activity	IDA	18194466
GO:0008191	Function	Metalloendopeptidase inhibitor activity	IEA
GO:0008191	Function	Metalloendopeptidase inhibitor activity	TAS	9789069
GO:0010716	Process	Negative regulation of extracellular matrix disassembly	IEA
GO:0010716	Process	Negative regulation of extracellular matrix disassembly	ISS
GO:0015026	Function	Coreceptor activity	IEA
GO:0016020	Component	Membrane	IEA
GO:0016020	Component	Membrane	TAS	9789069
GO:0016055	Process	Wnt signaling pathway	IEA
GO:0017147	Function	Wnt-protein binding	IEA
GO:0030198	Process	Extracellular matrix organization	IBA
GO:0030198	Process	Extracellular matrix organization	IEA
GO:0030336	Process	Negative regulation of cell migration	IMP	18591254
GO:0030414	Function	Peptidase inhibitor activity	IEA
GO:0035115	Process	Embryonic forelimb morphogenesis	IEA
GO:0045765	Process	Regulation of angiogenesis	IEA
GO:0060070	Process	Canonical Wnt signaling pathway	IEA
GO:0060828	Process	Regulation of canonical Wnt signaling pathway	IBA
GO:0090210	Process	Regulation of establishment of blood-brain barrier	IEA
GO:0090263	Process	Positive regulation of canonical Wnt signaling pathway	IEA
GO:0098552	Component	Side of membrane	IEA
GO:1903053	Process	Regulation of extracellular matrix organization	IMP	18591254
GO:1990909	Component	Wnt signalosome	IEA

MIM	HGNC	e!Ensembl
605227	11345	ENSG00000122707

O95980

Protein name

Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) (Suppressor of tumorigenicity 15 protein)

Protein function

Functions together with ADGRA2 to enable brain endothelial cells to selectively respond to Wnt7 signals (WNT7A or WNT7B) (PubMed:28289266, PubMed:30026314). Plays a key role in Wnt7-specific responses: required for central nervous system (CNS) a

PDB

8TZP

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF07648	Kazal_2	631 → 671	Kazal-type serine protease inhibitor domain	Domain
PF07648	Kazal_2	712 → 750	Kazal-type serine protease inhibitor domain	Domain
PF07648	Kazal_2	749 → 787	Kazal-type serine protease inhibitor domain	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in various tissues and untransformed cells (PubMed:9789069). It is undetectable in tumor-derived cell lines and oncogenically transformed cells (PubMed:9789069). {ECO:0000269|PubMed:9789069}.

Sequence

MATVRASLRGALLLLLAVAGVAEVAGGLAPGSAGALCCNHSKDNQMCRDVCEQIFSSKSE
SRLKHLLQRAPDYCPETMVEIWNCMNSSLPGVFKKSDGWVGLGCCELAIALECRQACKQA
SSKNDISKVCRKEYENALFSCISRNEMGSVCCSYAGHHTNCREYCQAIFRTDSSPGPSQI
KAVENYCASISPQLIHCVNNYTQSYPMRNPTDSLYCCDRAEDHACQNACKRILMSKKTEM
EIVDGLIEGCKTQPLPQDPLWQCFLESSQSVHPGVTVHPPPSTGLDGAKLHCCSKANTST
CRELCTKLYSMSWGNTQSWQEFDRFCEYNPVEVSMLTCLADVREPCQLGCRNLTYCTNFN
NRPTELFRSCNAQSDQGAMNDMKLWEKGSIKMPFINIPVLDIKKCQPEMWKAIACSLQIK
PCHSKSRGSIICKSDCVEILKKCGDQNKFPEDHTAESICELLSPTDDLKNCIPLDTYLRP
STLGNIVEEVTHPCNPNPCPANELCEVNRKGCPSGDPCLPYFCVQGCKLGEASDFIVRQG
TLIQVPSSAGEVGCYKICSCGQSGLLENCMEMHCIDLQKSCIVGGKRKSHGTSFSIDCNV
CSCFAGNLVCSTRLCLSEHSSEDDRRTFTGLPCNCADQFVPVCGQNGRTYPSACIARCVG
LQDHQFEFGSCMSKDPCNPNPCQKNQRCIPKPQVCLTTFDKFGCSQYECVPRQLACDQVQ
DPVCDTDHMEHNNLCTLYQRGKSLSYKGPCQPFCRATEPVCGHNGETYSSVCAAYSDRVA
VDYYGDCQAVGVLSEHSSVAECASVKCPSLLAAGCKPIIPPGACCPLCAGMLRVLFDKEK
LDTIAKVTNKKPITVLEILQKIRMHVSVPQCDVFGYFSIESEIVILIIPVDHYPKALQIE
ACNKEAEKIESLINSDSPTLASHVPLSALIISQVQVSSSVPSAGVRARPSCHSLLLPLSL
GLALHLLWTYN

Sequence length

971

Interactions

View interactions

	KEGG		Reactome
	MicroRNAs in cancer		Post-translational modification: synthesis of GPI-anchored proteins

Show/Hide Unknown Diseases (9)

Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Unknown Diseases with uncertain, conflicting, or no pathogenic evidence in ClinVar
Cervical cancer	Benign	rs71521299	RCV005905264
Chronic lymphocytic leukemia/small lymphocytic lymphoma	Benign	rs71521299	RCV005905270
Clear cell carcinoma of kidney	Uncertain significance; Benign	rs112938194, rs71521299	RCV005930689 RCV005905265
Familial cancer of breast	Uncertain significance	rs112938194	RCV005930688
Familial pancreatic carcinoma	Benign	rs71521299	RCV005905266
Gastric cancer	Uncertain significance; Benign	rs112938194, rs71521299	RCV005930690 RCV005905268
Lung cancer	Benign	rs71521299	RCV005905269
Nonpapillary renal cell carcinoma	Benign	rs71521299	RCV005905263
Sarcoma	Benign	rs71521299	RCV005905267

Show/Hide Text Mining Associations (70)

Disease Name	Relationship Type	References
Associations from Text MiningDisease associations identified through Pubtator
Abdominal Injuries	Associate	27268601
Adenocarcinoma	Associate	20032402
Adenoma Oxyphilic	Inhibit	24131772
Alzheimer Disease	Stimulate	33731436
Ameloblastoma	Inhibit	19995435
Arthritis Rheumatoid	Inhibit	15485996
Asthma	Inhibit	17088949
Asthma	Associate	36835202
Breast Neoplasms	Associate	12767082, 18263644, 22404079, 24833255, 26449734, 27058625, 38041032
Breast Neoplasms	Inhibit	21255571
Bronchial Hyperreactivity	Associate	36835202
Calcinosis Cutis	Associate	19144199, 22260435
Carcinogenesis	Associate	22438955
Carcinoma Adenoid Cystic	Associate	25517920
Carcinoma Hepatocellular	Associate	22419890, 22428065, 25278269, 25537516, 27268601, 32522890
Carcinoma Non Small Cell Lung	Associate	17233834, 20032402, 25084400, 32138716, 33580150
Carcinoma Pancreatic Ductal	Associate	23749490
Carcinoma Renal Cell	Inhibit	24131772
Carcinoma Squamous Cell	Inhibit	20032402
Carcinoma Squamous Cell	Associate	24356192, 25084400
Cartilage Diseases	Associate	20395433
Colorectal Neoplasms	Associate	31210300, 32221048, 35444107
Coronary Artery Disease	Associate	34205376
Coronary Disease	Associate	34205376
Dermatitis Atopic	Associate	37432109
Diabetic Nephropathies	Associate	31862399
Ectodermal Dysplasia	Associate	25517920
Edema	Associate	27268601
Endometriosis	Stimulate	39519143
Epstein Barr Virus Infections	Associate	25031745
Esophageal Neoplasms	Associate	18023103
Esophageal Squamous Cell Carcinoma	Associate	18023103, 24852767, 31866421
Gallbladder Neoplasms	Associate	32206004
Glioma	Associate	26431549, 28208619
Helicobacter Infections	Inhibit	18794849
Hepatoblastoma	Associate	25987077
Hyperglycemia	Associate	31862399
Inflammation	Inhibit	38387446
Lupus Erythematosus Systemic	Inhibit	18652766
Lupus Nephritis	Associate	40045202
Lymphatic Metastasis	Associate	17233834, 18023103, 23679328, 23749490, 27268601
Mouth Neoplasms	Associate	18665171, 27696293
Nasopharyngeal Carcinoma	Associate	25031745
Nasopharyngitis	Inhibit	25031745
Neoplasm Invasiveness	Inhibit	26449734
Neoplasm Metastasis	Inhibit	17233834, 18665171, 20579139, 20973064, 22404079, 25278269, 26459448, 27058625
Neoplasm Metastasis	Associate	21255571, 22428065, 23679328, 25031745, 25278269, 25537516, 26130413, 26141647, 27268601, 35444107, 37904179
Neoplasms	Inhibit	12767082, 15928670, 16619545, 17233834, 17262820, 18023103, 18665171, 20579139, 20973064, 21255571, 22404079, 22428065, 22438955, 25278269, 25517920 View all (5 more)
Neoplasms	Associate	19509549, 20143471, 22139647, 22321642, 23820254, 24131772, 25031745, 25537516, 26141647, 26592832, 27268601, 29874120, 35444107, 37904179
Nerve Sheath Neoplasms	Inhibit	16619545
Neuroblastoma	Associate	20579139, 23176145, 25987077
Odontogenic Tumors	Inhibit	19995435
Odontoma	Inhibit	19995435
Osteosarcoma	Associate	17262820, 20973064
Osteosarcoma	Inhibit	26130413
Ovarian Diseases	Associate	39519143
Ovarian Neoplasms	Associate	33941323
Periodontal Diseases	Associate	27272560
Prostatic Neoplasms	Associate	15928670, 22139647, 22642976
Pulmonary Disease Chronic Obstructive	Inhibit	38387446
Sarcoidosis	Inhibit	27575817
Squamous Cell Carcinoma of Head and Neck	Associate	31349748
Stomach Neoplasms	Associate	18794849, 20143471, 22321642, 25516656, 26364844, 37904179
Synovitis	Associate	31074012
Tertiary Lymphoid Structures	Inhibit	21255571
Tertiary Lymphoid Structures	Associate	25278269
Urinary Bladder Neoplasms	Associate	23226455
Uterine Cervical Neoplasms	Associate	23679328
Vascular Diseases	Associate	31074012
Wilms Tumor	Associate	26141647

RECK (reversion inducing cysteine rich protein with kazal motifs)