SGIP1 (SH3GL interacting endocytic adaptor 1)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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84251 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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SH3GL interacting endocytic adaptor 1 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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SGIP1 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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Chromosome
Chromosome number
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1 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1p31.3 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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SGIP1 functions as an endocytic protein that affects signaling by receptors in neuronal systems involved in energy homeostasis via its interaction with endophilins (see SH3GL3; MIM 603362) (Trevaskis et al., 2005 [PubMed 15919751] and Uezu et al., 2007 [P |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | |||||||||||
| UniProt ID | Q9BQI5 | ||||||||||
| Protein name | SH3-containing GRB2-like protein 3-interacting protein 1 (Endophilin-3-interacting protein) | ||||||||||
| Protein function | May function in clathrin-mediated endocytosis. Has both a membrane binding/tubulating activity and the ability to recruit proteins essential to the formation of functional clathrin-coated pits. Has a preference for membranes enriched in phosphat | ||||||||||
| PDB | 5AWR , 5AWS , 5AWT , 5AWU , 6A9Y | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Specifically expressed in brain. {ECO:0000269|PubMed:15919751}. | ||||||||||
| Sequence |
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| Sequence length | 828 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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