CHD6 (chromodomain helicase DNA binding protein 6)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 84181 |
| Gene name | Chromodomain helicase DNA binding protein 6 |
| Gene symbol | CHD6 |
| Synonyms (NCBI Gene) |
CHD-6CHD5RIGB
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| Chromosome | 20 |
| Chromosome location | 20q12 |
| Summary | This gene encodes a member of the SNF2/RAD54 helicase protein family. The encoded protein contains two chromodomains, a helicase domain, and an ATPase domain. Several multi-subunit protein complexes remodel chromatin to allow patterns of cell type-specifi |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q8TD26 | |||||||||||||||||||||||||
| Protein name | Chromodomain-helicase-DNA-binding protein 6 (CHD-6) (EC 3.6.4.-) (ATP-dependent helicase CHD6) (Radiation-induced gene B protein) | |||||||||||||||||||||||||
| Protein function | ATP-dependent chromatin-remodeling factor (PubMed:17027977, PubMed:28533432). Regulates transcription by disrupting nucleosomes in a largely non-sliding manner which strongly increases the accessibility of chromatin; nucleosome disruption requir | |||||||||||||||||||||||||
| PDB | 2EPB | |||||||||||||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed. | |||||||||||||||||||||||||
| Sequence |
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| Sequence length | 2715 | |||||||||||||||||||||||||
| Interactions | View interactions | |||||||||||||||||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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