FRMD8 (FERM domain containing 8)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 83786 |
| Gene name | FERM domain containing 8 |
| Gene symbol | FRMD8 |
| Synonyms (NCBI Gene) |
FKSG44iTAP
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| Chromosome | 11 |
| Chromosome location | 11q13.1 |
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miRNA
miRNA information provided by mirtarbase database.
467
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
14
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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Q9BZ67 | ||||||||||
| Protein name | FERM domain-containing protein 8 (Band4.1 inhibitor LRP interactor) (Bili) (iRhom tail-associated protein) (iTAP) | ||||||||||
| Protein function | Promotes the cell surface stability of iRhom1/RHBDF1 and iRhom2/RHBDF2 and prevents their degradation via the endolysosomal pathway. By acting on iRhoms, involved in ADAM17-mediated shedding of TNF, amphiregulin/AREG, HBEGF and TGFA from the cel | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Widely expressed, with high expression in heart and spleen. {ECO:0000269|PubMed:19572019}. | ||||||||||
| Sequence |
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| Sequence length | 464 | ||||||||||
| Interactions | View interactions | ||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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