PCDH11Y (protocadherin 11 Y-linked)

Gene

• Entrez ID: 83259
• Gene name: Protocadherin 11 Y-linked
• Gene symbol: PCDH11Y
• Synonyms (NCBI Gene): PCDH-PC, PCDH22, PCDHX, PCDHY
• Chromosome: Y
• Chromosome location: Yp11.2
• Summary: This gene belongs to the protocadherin family, a subfamily of the cadherin superfamily. The encoded protein consists of an extracellular domain containing seven cadherin repeats, a transmembrane domain, and a cytoplasmic tail that differs from those of th

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT655355	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT655354	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT655353	hsa-miR-324-5p	HITS-CLIP	23824327
MIRT655352	hsa-miR-4775	HITS-CLIP	23824327
MIRT655351	hsa-miR-432-3p	HITS-CLIP	23824327
MIRT555821	hsa-miR-383-5p	PAR-CLIP	20371350
MIRT555820	hsa-miR-5694	PAR-CLIP	20371350
MIRT555819	hsa-miR-511-3p	PAR-CLIP	20371350
MIRT555818	hsa-miR-3935	PAR-CLIP	20371350
MIRT555817	hsa-miR-376a-2-5p	PAR-CLIP	20371350
MIRT555816	hsa-miR-567	PAR-CLIP	20371350
MIRT555815	hsa-miR-223-5p	PAR-CLIP	20371350
MIRT555814	hsa-miR-6867-5p	PAR-CLIP	20371350
MIRT555813	hsa-miR-297	PAR-CLIP	20371350
MIRT555812	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT555821	hsa-miR-383-5p	PAR-CLIP	21572407
MIRT555820	hsa-miR-5694	PAR-CLIP	21572407
MIRT555819	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT555818	hsa-miR-3935	PAR-CLIP	21572407
MIRT555817	hsa-miR-376a-2-5p	PAR-CLIP	21572407
MIRT555816	hsa-miR-567	PAR-CLIP	21572407
MIRT555815	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT555814	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT555813	hsa-miR-297	PAR-CLIP	21572407
MIRT555812	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT555815	hsa-miR-223-5p	HITS-CLIP	27418678
MIRT555813	hsa-miR-297	HITS-CLIP	27418678
MIRT555817	hsa-miR-376a-2-5p	HITS-CLIP	27418678
MIRT555821	hsa-miR-383-5p	HITS-CLIP	27418678
MIRT555818	hsa-miR-3935	HITS-CLIP	27418678
MIRT555819	hsa-miR-511-3p	HITS-CLIP	27418678
MIRT555816	hsa-miR-567	HITS-CLIP	27418678
MIRT555820	hsa-miR-5694	HITS-CLIP	27418678
MIRT555812	hsa-miR-574-5p	HITS-CLIP	27418678
MIRT555814	hsa-miR-6867-5p	HITS-CLIP	27418678
MIRT655355	hsa-miR-590-3p	HITS-CLIP	23824327
MIRT655354	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT655353	hsa-miR-324-5p	HITS-CLIP	23824327
MIRT655352	hsa-miR-4775	HITS-CLIP	23824327
MIRT655351	hsa-miR-432-3p	HITS-CLIP	23824327
MIRT555821	hsa-miR-383-5p	PAR-CLIP	20371350
MIRT555820	hsa-miR-5694	PAR-CLIP	20371350
MIRT555819	hsa-miR-511-3p	PAR-CLIP	20371350
MIRT555818	hsa-miR-3935	PAR-CLIP	20371350
MIRT555817	hsa-miR-376a-2-5p	PAR-CLIP	20371350
MIRT555816	hsa-miR-567	PAR-CLIP	20371350
MIRT555815	hsa-miR-223-5p	PAR-CLIP	20371350
MIRT555814	hsa-miR-6867-5p	PAR-CLIP	20371350
MIRT555813	hsa-miR-297	PAR-CLIP	20371350
MIRT555812	hsa-miR-574-5p	PAR-CLIP	20371350
MIRT555821	hsa-miR-383-5p	PAR-CLIP	21572407
MIRT555820	hsa-miR-5694	PAR-CLIP	21572407
MIRT555819	hsa-miR-511-3p	PAR-CLIP	21572407
MIRT555818	hsa-miR-3935	PAR-CLIP	21572407
MIRT555817	hsa-miR-376a-2-5p	PAR-CLIP	21572407
MIRT555816	hsa-miR-567	PAR-CLIP	21572407
MIRT555815	hsa-miR-223-5p	PAR-CLIP	21572407
MIRT555814	hsa-miR-6867-5p	PAR-CLIP	21572407
MIRT555813	hsa-miR-297	PAR-CLIP	21572407
MIRT555812	hsa-miR-574-5p	PAR-CLIP	21572407
MIRT1216703	hsa-miR-1307	CLIP-seq
MIRT1216704	hsa-miR-4284	CLIP-seq
MIRT1216705	hsa-miR-4638-5p	CLIP-seq
MIRT1216706	hsa-miR-566	CLIP-seq
MIRT1216707	hsa-miR-122	CLIP-seq
MIRT1216703	hsa-miR-1307	CLIP-seq
MIRT1216708	hsa-miR-3135b	CLIP-seq
MIRT1216709	hsa-miR-3652	CLIP-seq
MIRT1216710	hsa-miR-4430	CLIP-seq
MIRT1216705	hsa-miR-4638-5p	CLIP-seq
MIRT1216706	hsa-miR-566	CLIP-seq
MIRT1216711	hsa-miR-1243	CLIP-seq
MIRT1216712	hsa-miR-186	CLIP-seq
MIRT1216713	hsa-miR-3171	CLIP-seq
MIRT1216714	hsa-miR-3654	CLIP-seq
MIRT1216715	hsa-miR-3668	CLIP-seq
MIRT1216716	hsa-miR-374a	CLIP-seq
MIRT1216717	hsa-miR-374b	CLIP-seq
MIRT1216718	hsa-miR-4318	CLIP-seq
MIRT1216719	hsa-miR-4477a	CLIP-seq
MIRT1216720	hsa-miR-4477b	CLIP-seq
MIRT1216721	hsa-miR-4652-3p	CLIP-seq
MIRT1216722	hsa-miR-4693-5p	CLIP-seq
MIRT1216723	hsa-miR-4778-5p	CLIP-seq
MIRT1216724	hsa-miR-656	CLIP-seq
MIRT1216725	hsa-miR-668	CLIP-seq
MIRT1216726	hsa-miR-671-5p	CLIP-seq
MIRT1216727	hsa-miR-889	CLIP-seq
MIRT1216728	hsa-miR-892a	CLIP-seq
MIRT1216712	hsa-miR-186	CLIP-seq
MIRT2062555	hsa-miR-2276	CLIP-seq
MIRT2062556	hsa-miR-3607-5p	CLIP-seq
MIRT2062557	hsa-miR-4274	CLIP-seq
MIRT2062558	hsa-miR-4282	CLIP-seq
MIRT2062559	hsa-miR-455-5p	CLIP-seq
MIRT1216722	hsa-miR-4693-5p	CLIP-seq
MIRT2062560	hsa-miR-4696	CLIP-seq
MIRT2062561	hsa-miR-550a	CLIP-seq
MIRT2062562	hsa-miR-627	CLIP-seq
MIRT2290964	hsa-miR-1272	CLIP-seq
MIRT2290965	hsa-miR-1276	CLIP-seq
MIRT2290966	hsa-miR-1296	CLIP-seq
MIRT2290967	hsa-miR-137	CLIP-seq
MIRT2290968	hsa-miR-2277-3p	CLIP-seq
MIRT2290969	hsa-miR-25	CLIP-seq
MIRT2290970	hsa-miR-2909	CLIP-seq
MIRT2290971	hsa-miR-3065-5p	CLIP-seq
MIRT2290972	hsa-miR-3182	CLIP-seq
MIRT2290973	hsa-miR-32	CLIP-seq
MIRT2290974	hsa-miR-3613-3p	CLIP-seq
MIRT2290975	hsa-miR-363	CLIP-seq
MIRT2290976	hsa-miR-367	CLIP-seq
MIRT2290977	hsa-miR-3682-3p	CLIP-seq
MIRT2290978	hsa-miR-4311	CLIP-seq
MIRT2290979	hsa-miR-4325	CLIP-seq
MIRT2290980	hsa-miR-4436b-3p	CLIP-seq
MIRT2290981	hsa-miR-4636	CLIP-seq
MIRT2290982	hsa-miR-4680-5p	CLIP-seq
MIRT2290983	hsa-miR-4711-3p	CLIP-seq
MIRT2290984	hsa-miR-4744	CLIP-seq
MIRT2290985	hsa-miR-4761-3p	CLIP-seq
MIRT2290986	hsa-miR-548ac	CLIP-seq
MIRT2290987	hsa-miR-548ae	CLIP-seq
MIRT2290988	hsa-miR-548aj	CLIP-seq
MIRT2290989	hsa-miR-548am	CLIP-seq
MIRT2290990	hsa-miR-548d-3p	CLIP-seq
MIRT2290991	hsa-miR-548x	CLIP-seq
MIRT2290992	hsa-miR-548z	CLIP-seq
MIRT2290993	hsa-miR-570	CLIP-seq
MIRT2290994	hsa-miR-582-5p	CLIP-seq
MIRT2290995	hsa-miR-583	CLIP-seq
MIRT2290996	hsa-miR-618	CLIP-seq
MIRT2290997	hsa-miR-922	CLIP-seq
MIRT2290998	hsa-miR-92a	CLIP-seq
MIRT2290999	hsa-miR-92b	CLIP-seq
MIRT1216711	hsa-miR-1243	CLIP-seq
MIRT1216712	hsa-miR-186	CLIP-seq
MIRT1216714	hsa-miR-3654	CLIP-seq
MIRT1216718	hsa-miR-4318	CLIP-seq
MIRT2392192	hsa-miR-4668-3p	CLIP-seq
MIRT1216722	hsa-miR-4693-5p	CLIP-seq
MIRT1216726	hsa-miR-671-5p	CLIP-seq
MIRT1216728	hsa-miR-892a	CLIP-seq
MIRT1216707	hsa-miR-122	CLIP-seq
MIRT2588601	hsa-miR-1270	CLIP-seq
MIRT2588602	hsa-miR-1273f	CLIP-seq
MIRT2588603	hsa-miR-1281	CLIP-seq
MIRT2588604	hsa-miR-129-5p	CLIP-seq
MIRT1216703	hsa-miR-1307	CLIP-seq
MIRT2588605	hsa-miR-1976	CLIP-seq
MIRT2062555	hsa-miR-2276	CLIP-seq
MIRT1216708	hsa-miR-3135b	CLIP-seq
MIRT2588606	hsa-miR-3149	CLIP-seq
MIRT2588607	hsa-miR-3199	CLIP-seq
MIRT2588608	hsa-miR-3591-5p	CLIP-seq
MIRT1216709	hsa-miR-3652	CLIP-seq
MIRT2588609	hsa-miR-3658	CLIP-seq
MIRT2588610	hsa-miR-3681	CLIP-seq
MIRT2588611	hsa-miR-3913-3p	CLIP-seq
MIRT2588612	hsa-miR-4258	CLIP-seq
MIRT2588613	hsa-miR-4279	CLIP-seq
MIRT1216704	hsa-miR-4284	CLIP-seq
MIRT2588614	hsa-miR-4426	CLIP-seq
MIRT1216710	hsa-miR-4430	CLIP-seq
MIRT2588615	hsa-miR-4438	CLIP-seq
MIRT2588616	hsa-miR-4460	CLIP-seq
MIRT2588617	hsa-miR-4532	CLIP-seq
MIRT1216705	hsa-miR-4638-5p	CLIP-seq
MIRT2588618	hsa-miR-4647	CLIP-seq
MIRT2588619	hsa-miR-4662b	CLIP-seq
MIRT2588620	hsa-miR-4683	CLIP-seq
MIRT2588621	hsa-miR-4707-3p	CLIP-seq
MIRT2588622	hsa-miR-4722-3p	CLIP-seq
MIRT2588623	hsa-miR-4727-3p	CLIP-seq
MIRT2588624	hsa-miR-4735-5p	CLIP-seq
MIRT2588625	hsa-miR-4740-3p	CLIP-seq
MIRT2588626	hsa-miR-5095	CLIP-seq
MIRT1216706	hsa-miR-566	CLIP-seq
MIRT2588627	hsa-miR-620	CLIP-seq
MIRT1216707	hsa-miR-122	CLIP-seq
MIRT2588601	hsa-miR-1270	CLIP-seq
MIRT2588603	hsa-miR-1281	CLIP-seq
MIRT2588604	hsa-miR-129-5p	CLIP-seq
MIRT1216703	hsa-miR-1307	CLIP-seq
MIRT2588605	hsa-miR-1976	CLIP-seq
MIRT2062555	hsa-miR-2276	CLIP-seq
MIRT1216708	hsa-miR-3135b	CLIP-seq
MIRT2588606	hsa-miR-3149	CLIP-seq
MIRT2588607	hsa-miR-3199	CLIP-seq
MIRT2588608	hsa-miR-3591-5p	CLIP-seq
MIRT1216709	hsa-miR-3652	CLIP-seq
MIRT2588610	hsa-miR-3681	CLIP-seq
MIRT2588612	hsa-miR-4258	CLIP-seq
MIRT2588613	hsa-miR-4279	CLIP-seq
MIRT1216704	hsa-miR-4284	CLIP-seq
MIRT1216710	hsa-miR-4430	CLIP-seq
MIRT2588615	hsa-miR-4438	CLIP-seq
MIRT2588616	hsa-miR-4460	CLIP-seq
MIRT2588617	hsa-miR-4532	CLIP-seq
MIRT1216705	hsa-miR-4638-5p	CLIP-seq
MIRT2588620	hsa-miR-4683	CLIP-seq
MIRT2588621	hsa-miR-4707-3p	CLIP-seq
MIRT2588622	hsa-miR-4722-3p	CLIP-seq
MIRT2588623	hsa-miR-4727-3p	CLIP-seq
MIRT2588624	hsa-miR-4735-5p	CLIP-seq
MIRT2588625	hsa-miR-4740-3p	CLIP-seq
MIRT2588626	hsa-miR-5095	CLIP-seq
MIRT1216706	hsa-miR-566	CLIP-seq
MIRT2588627	hsa-miR-620	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005509	Function	Calcium ion binding	IEA
GO:0005886	Component	Plasma membrane	IBA
GO:0005886	Component	Plasma membrane	IEA
GO:0007155	Process	Cell adhesion	IBA
GO:0007155	Process	Cell adhesion	IEA
GO:0007156	Process	Homophilic cell adhesion via plasma membrane adhesion molecules	IEA
GO:0007283	Process	Spermatogenesis	IMP	28241900
GO:0016020	Component	Membrane	IEA
GO:0030177	Process	Positive regulation of Wnt signaling pathway	IMP	28241900
GO:0050839	Function	Cell adhesion molecule binding	IBA
GO:0061827	Component	Sperm head	IDA	28241900
GO:0097225	Component	Sperm midpiece	IDA	28241900

Other IDs

• MIM: 400022
• HGNC: 15813
• e!Ensembl: ENSG00000099715

Protein

• UniProt ID: Q9BZA8
• Protein name: Protocadherin-11 Y-linked (Protocadherin-11) (Protocadherin on the Y chromosome) (PCDH-Y) (Protocadherin prostate cancer) (Protocadherin-PC) (Protocadherin-22)
• Protein function: Potential calcium-dependent cell-adhesion protein.
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF08266	Cadherin_2	57 → 147	Cadherin-like	Domain
  PF00028	Cadherin	176 → 272	Cadherin domain	Domain
  PF00028	Cadherin	286 → 378	Cadherin domain	Domain
  PF00028	Cadherin	398 → 489	Cadherin domain	Domain
  PF00028	Cadherin	503 → 593	Cadherin domain	Domain
  PF00028	Cadherin	607 → 696	Cadherin domain	Domain
  PF00028	Cadherin	714 → 805	Cadherin domain	Domain
  PF08374	Protocadherin	807 → 1030	Protocadherin	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed strongly in fetal brain and brain (cortex, amygdala, thalamus, substantia nigra, hippocampus, caudate nucleus and corpus callosum). Expressed at low level in testis. Expressed in apoptosis-resistant cells. {ECO:0000269|PubMed
• Sequence:

  MFRVGFLIISSSSSLSPLLLVSVVRVNTTNCHKCLLSGTYIFAVLLVCVVFHSGAQEKNY
  TIREEIPENVLIGNLLKDLNLSLIPNKSLTTTMQFKLVYKTGDVPLIRIEEDTGEIFTTG
  ARIDREKLCAGIPRDEHCFYEVEVAILPDEIFRLVKIRFLIEDINDNAPLFPATVINISI
  PENSAINSKYTLPAAVDPDVGINGVQNYELIKSQNIFGLDVIETPEGDKMPQLIVQKELD
  REEKDTYVMKVKVEDGGFPQRSSTAILQVSVTDTNDNHPVFKETEIEVSIPENAPVGTSV
  TQLHATDADIGENAKIHFSFSNLVSNIARRLFHLNATTGLITIKEPLDREETPNHKLLVL
  ASDGGLMPARAMVLVNVTDVNDNVPSIDIRYIVNPVNDTVVLSENIPLNTKIALITVTDK
  DADHNGRVTCFTDHEIPFRLRPVFSNQFLLENAAYLDYESTKEYAIKLLAADAGKPPLNQ
  SAMLFIKVKDENDNAPVFTQSFVTVSIPENNSPGIQLMKVSATDADSGPNAEINYLLGPD
  APPEFSLDRRTGMLTVVKKLDREKEDKYLFTILAKDNGVPPLTSNVTVFVSIIDQNDNSP
  VFTHNEYKFYVPENLPRHGTVGLITVTDPDYGDNSAVTLSILDENDDFTIDSQTGVIRPN
  ISFDREKQESYTFYVKAEDGGRVSRSSSAKVTINVVDVNDNKPVFIVPPYNYSYELVLPS
  TNPGTVVFQVIAVDNDTGMNAEVRYSIVGGNTRDLFAIDQETGNITLMEKCDVTDLGLHR
  VLVKANDLGQPDSLFSVVIVNLFVNESVTNATLINELVRKSIEAPVTPNTEIADVSSPTS
  DYVKILVAAVAGTITVVVVIFITAVVRCRQAPHLKAAQKNMQNSEWATPNPENRQMIMMK
  KKKKKKKHSPKNLLLNVVTIEETKADDVDSDGNRVTLDLPIDLEEQTMGKYNWVTTPTTF
  KPDSPDLARHYKSASPQPAFQIQPETPLNLKHHIIQELPLDNTFVACDSISNCSSSSSDP
  YSVSDCGYPVTTFEVPVSVHTRPSQRRVTFHLPEGSQESSSDGGLGDHDAGSLTSTSHGL
  PLGYPQEEYFDRATPSNRTEGDGNSDPESTFIPGLKKEITVQPTVEEASDNCTQECLIYG
  HSDACWMPASLDHSSSSQAQASALCHSPPLSQASTQHHSPPVTQTIVLCHSPPVTQTIAL
  CHSPPPIQVSALHHSPPLVQGTALHHSPPSAQASALCYSPPLAQAAAISHSSSLPQVIAL
  HRSQAQSSVSLQQGWVQGANGLCSVDQGVQGSATSQFYTMSERLHPSDDSIKVIPLTTFA
  PRQQARPSRGDSPIMETHPL

• Sequence length: 1340

Pathways

KEGG:

Virion - Lassa virus and SFTS virus