Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	81831
Gene name Gene Name - the full gene name approved by the HGNC.	Neuropilin and tolloid like 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	NETO2
Synonyms (NCBI Gene) Gene synonyms aliases	BTCL2, NEOT2
Chromosome Chromosome number	16
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	16q12.1
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a predicted transmembrane protein containing two extracellular CUB domains followed by a low-density lipoprotein class A (LDLa) domain. A similar gene in rats encodes a protein that modulates glutamate signaling in the brain by regulatin

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miRTarBase ID	miRNA	Experiments	Reference
MIRT002815	hsa-miR-1-3p	Luciferase reporter assay, Microarray	15685193
MIRT020025	hsa-miR-375	Microarray	20215506
MIRT002815	hsa-miR-1-3p	Microarray	18668037
MIRT002815	hsa-miR-1-3p	Microarray	15685193
MIRT030591	hsa-miR-24-3p	Microarray	19748357
MIRT031045	hsa-miR-21-5p	Microarray	18591254
MIRT050610	hsa-miR-20a-5p	CLASH	23622248
MIRT672732	hsa-miR-4753-5p	HITS-CLIP	23824327
MIRT672731	hsa-miR-4493	HITS-CLIP	23824327
MIRT672730	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT672729	hsa-miR-4284	HITS-CLIP	23824327
MIRT030591	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT547340	hsa-miR-548ad-3p	PAR-CLIP	21572407
MIRT547339	hsa-miR-424-3p	PAR-CLIP	21572407
MIRT547338	hsa-miR-3662	PAR-CLIP	21572407
MIRT547337	hsa-miR-3646	PAR-CLIP	21572407
MIRT547336	hsa-miR-224-3p	PAR-CLIP	21572407
MIRT547335	hsa-miR-522-3p	PAR-CLIP	21572407
MIRT547334	hsa-miR-4495	PAR-CLIP	21572407
MIRT547333	hsa-miR-379-3p	PAR-CLIP	21572407
MIRT547332	hsa-miR-411-3p	PAR-CLIP	21572407
MIRT547331	hsa-miR-380-3p	PAR-CLIP	21572407
MIRT547330	hsa-miR-203a-3p	PAR-CLIP	21572407
MIRT547329	hsa-miR-3924	PAR-CLIP	21572407
MIRT472346	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT472345	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT472344	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT472343	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT050610	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT472342	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT472341	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT472340	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT547328	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT547327	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT472339	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT472338	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT472337	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT472336	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT472335	hsa-miR-382-5p	PAR-CLIP	21572407
MIRT472334	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT472333	hsa-miR-3190-3p	PAR-CLIP	21572407
MIRT472329	hsa-miR-4480	PAR-CLIP	21572407
MIRT472348	hsa-miR-7160-3p	PAR-CLIP	23592263
MIRT472349	hsa-miR-342-3p	PAR-CLIP	23592263
MIRT472347	hsa-miR-1229-3p	PAR-CLIP	23592263
MIRT472346	hsa-miR-106a-5p	PAR-CLIP	23592263
MIRT472345	hsa-miR-526b-3p	PAR-CLIP	23592263
MIRT472344	hsa-miR-20b-5p	PAR-CLIP	23592263
MIRT472343	hsa-miR-93-5p	PAR-CLIP	23592263
MIRT050610	hsa-miR-20a-5p	PAR-CLIP	23592263
MIRT472342	hsa-miR-17-5p	PAR-CLIP	23592263
MIRT472341	hsa-miR-519d-3p	PAR-CLIP	23592263
MIRT472340	hsa-miR-106b-5p	PAR-CLIP	23592263
MIRT472339	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT472338	hsa-miR-519a-3p	PAR-CLIP	23592263
MIRT472337	hsa-miR-519b-3p	PAR-CLIP	23592263
MIRT472336	hsa-miR-519c-3p	PAR-CLIP	23592263
MIRT472335	hsa-miR-382-5p	PAR-CLIP	23592263
MIRT472334	hsa-miR-143-5p	PAR-CLIP	23592263
MIRT472333	hsa-miR-3190-3p	PAR-CLIP	23592263
MIRT472332	hsa-miR-526b-5p	PAR-CLIP	23592263
MIRT472331	hsa-miR-3161	PAR-CLIP	23592263
MIRT472330	hsa-miR-599	PAR-CLIP	23592263
MIRT472329	hsa-miR-4480	PAR-CLIP	23592263
MIRT672732	hsa-miR-4753-5p	HITS-CLIP	23824327
MIRT672731	hsa-miR-4493	HITS-CLIP	23824327
MIRT672730	hsa-miR-4755-3p	HITS-CLIP	23824327
MIRT672729	hsa-miR-4284	HITS-CLIP	23824327
MIRT030591	hsa-miR-24-3p	HITS-CLIP	23824327
MIRT547340	hsa-miR-548ad-3p	PAR-CLIP	21572407
MIRT547339	hsa-miR-424-3p	PAR-CLIP	21572407
MIRT547338	hsa-miR-3662	PAR-CLIP	21572407
MIRT547337	hsa-miR-3646	PAR-CLIP	21572407
MIRT547336	hsa-miR-224-3p	PAR-CLIP	21572407
MIRT547335	hsa-miR-522-3p	PAR-CLIP	21572407
MIRT547334	hsa-miR-4495	PAR-CLIP	21572407
MIRT547333	hsa-miR-379-3p	PAR-CLIP	21572407
MIRT547332	hsa-miR-411-3p	PAR-CLIP	21572407
MIRT547331	hsa-miR-380-3p	PAR-CLIP	21572407
MIRT547330	hsa-miR-203a-3p	PAR-CLIP	21572407
MIRT547329	hsa-miR-3924	PAR-CLIP	21572407
MIRT472346	hsa-miR-106a-5p	PAR-CLIP	21572407
MIRT472345	hsa-miR-526b-3p	PAR-CLIP	21572407
MIRT472344	hsa-miR-20b-5p	PAR-CLIP	21572407
MIRT472343	hsa-miR-93-5p	PAR-CLIP	21572407
MIRT050610	hsa-miR-20a-5p	PAR-CLIP	21572407
MIRT472342	hsa-miR-17-5p	PAR-CLIP	21572407
MIRT472341	hsa-miR-519d-3p	PAR-CLIP	21572407
MIRT472340	hsa-miR-106b-5p	PAR-CLIP	21572407
MIRT547328	hsa-miR-548az-5p	PAR-CLIP	21572407
MIRT547327	hsa-miR-548t-5p	PAR-CLIP	21572407
MIRT472339	hsa-miR-4796-3p	PAR-CLIP	21572407
MIRT472338	hsa-miR-519a-3p	PAR-CLIP	21572407
MIRT472337	hsa-miR-519b-3p	PAR-CLIP	21572407
MIRT472336	hsa-miR-519c-3p	PAR-CLIP	21572407
MIRT472335	hsa-miR-382-5p	PAR-CLIP	21572407
MIRT472334	hsa-miR-143-5p	PAR-CLIP	21572407
MIRT472333	hsa-miR-3190-3p	PAR-CLIP	21572407
MIRT472329	hsa-miR-4480	PAR-CLIP	21572407
MIRT472348	hsa-miR-7160-3p	PAR-CLIP	23592263
MIRT472349	hsa-miR-342-3p	PAR-CLIP	23592263
MIRT472347	hsa-miR-1229-3p	PAR-CLIP	23592263
MIRT472346	hsa-miR-106a-5p	PAR-CLIP	23592263
MIRT472345	hsa-miR-526b-3p	PAR-CLIP	23592263
MIRT472344	hsa-miR-20b-5p	PAR-CLIP	23592263
MIRT472343	hsa-miR-93-5p	PAR-CLIP	23592263
MIRT050610	hsa-miR-20a-5p	PAR-CLIP	23592263
MIRT472342	hsa-miR-17-5p	PAR-CLIP	23592263
MIRT472341	hsa-miR-519d-3p	PAR-CLIP	23592263
MIRT472340	hsa-miR-106b-5p	PAR-CLIP	23592263
MIRT472339	hsa-miR-4796-3p	PAR-CLIP	23592263
MIRT472338	hsa-miR-519a-3p	PAR-CLIP	23592263
MIRT472337	hsa-miR-519b-3p	PAR-CLIP	23592263
MIRT472336	hsa-miR-519c-3p	PAR-CLIP	23592263
MIRT472335	hsa-miR-382-5p	PAR-CLIP	23592263
MIRT472334	hsa-miR-143-5p	PAR-CLIP	23592263
MIRT472333	hsa-miR-3190-3p	PAR-CLIP	23592263
MIRT472332	hsa-miR-526b-5p	PAR-CLIP	23592263
MIRT472331	hsa-miR-3161	PAR-CLIP	23592263
MIRT472330	hsa-miR-599	PAR-CLIP	23592263
MIRT472329	hsa-miR-4480	PAR-CLIP	23592263
MIRT755525	hsa-miR-193a-5p	Western blotting, RNA pull down assay	34671432
MIRT1180862	hsa-miR-101	CLIP-seq
MIRT1180863	hsa-miR-106a	CLIP-seq
MIRT1180864	hsa-miR-106b	CLIP-seq
MIRT1180865	hsa-miR-1229	CLIP-seq
MIRT1180866	hsa-miR-1262	CLIP-seq
MIRT1180867	hsa-miR-1271	CLIP-seq
MIRT1180868	hsa-miR-144	CLIP-seq
MIRT1180869	hsa-miR-151-3p	CLIP-seq
MIRT1180870	hsa-miR-154	CLIP-seq
MIRT1180871	hsa-miR-17	CLIP-seq
MIRT1180872	hsa-miR-1825	CLIP-seq
MIRT755525	hsa-miR-193a-5p	CLIP-seq
MIRT1180873	hsa-miR-199a-5p	CLIP-seq
MIRT1180874	hsa-miR-199b-5p	CLIP-seq
MIRT1180875	hsa-miR-203	CLIP-seq
MIRT1180876	hsa-miR-20a	CLIP-seq
MIRT1180877	hsa-miR-20b	CLIP-seq
MIRT1180878	hsa-miR-298	CLIP-seq
MIRT1180879	hsa-miR-299-3p	CLIP-seq
MIRT1180880	hsa-miR-3123	CLIP-seq
MIRT1180881	hsa-miR-3144-3p	CLIP-seq
MIRT1180882	hsa-miR-3156-5p	CLIP-seq
MIRT1180883	hsa-miR-3190	CLIP-seq
MIRT1180884	hsa-miR-323-3p	CLIP-seq
MIRT1180885	hsa-miR-338-5p	CLIP-seq
MIRT1180886	hsa-miR-3671	CLIP-seq
MIRT1180887	hsa-miR-3692	CLIP-seq
MIRT1180888	hsa-miR-3714	CLIP-seq
MIRT1180889	hsa-miR-380	CLIP-seq
MIRT1180890	hsa-miR-382	CLIP-seq
MIRT1180891	hsa-miR-4324	CLIP-seq
MIRT1180892	hsa-miR-4427	CLIP-seq
MIRT1180893	hsa-miR-4436b-5p	CLIP-seq
MIRT1180894	hsa-miR-4463	CLIP-seq
MIRT1180895	hsa-miR-4491	CLIP-seq
MIRT1180896	hsa-miR-4499	CLIP-seq
MIRT1180897	hsa-miR-4536	CLIP-seq
MIRT1180898	hsa-miR-4657	CLIP-seq
MIRT1180899	hsa-miR-4661-5p	CLIP-seq
MIRT1180900	hsa-miR-4666-3p	CLIP-seq
MIRT1180901	hsa-miR-4701-3p	CLIP-seq
MIRT1180902	hsa-miR-4724-5p	CLIP-seq
MIRT1180903	hsa-miR-4738-3p	CLIP-seq
MIRT1180904	hsa-miR-4756-3p	CLIP-seq
MIRT1180905	hsa-miR-4797-5p	CLIP-seq
MIRT1180906	hsa-miR-486-5p	CLIP-seq
MIRT1180907	hsa-miR-488	CLIP-seq
MIRT1180908	hsa-miR-494	CLIP-seq
MIRT1180909	hsa-miR-499-3p	CLIP-seq
MIRT1180910	hsa-miR-499a-3p	CLIP-seq
MIRT1180911	hsa-miR-518a-5p	CLIP-seq
MIRT1180912	hsa-miR-519a	CLIP-seq
MIRT1180913	hsa-miR-519d	CLIP-seq
MIRT1180914	hsa-miR-522	CLIP-seq
MIRT1180915	hsa-miR-527	CLIP-seq
MIRT1180916	hsa-miR-548ac	CLIP-seq
MIRT1180917	hsa-miR-548ae	CLIP-seq
MIRT1180918	hsa-miR-548aj	CLIP-seq
MIRT1180919	hsa-miR-548am	CLIP-seq
MIRT1180920	hsa-miR-548an	CLIP-seq
MIRT1180921	hsa-miR-548d-3p	CLIP-seq
MIRT1180922	hsa-miR-548t	CLIP-seq
MIRT1180923	hsa-miR-548x	CLIP-seq
MIRT1180924	hsa-miR-548z	CLIP-seq
MIRT1180925	hsa-miR-889	CLIP-seq
MIRT1180926	hsa-miR-93	CLIP-seq
MIRT1180927	hsa-miR-96	CLIP-seq
MIRT1180863	hsa-miR-106a	CLIP-seq
MIRT1180864	hsa-miR-106b	CLIP-seq
MIRT1180867	hsa-miR-1271	CLIP-seq
MIRT1180928	hsa-miR-1276	CLIP-seq
MIRT1180871	hsa-miR-17	CLIP-seq
MIRT755525	hsa-miR-193a-5p	CLIP-seq
MIRT1180929	hsa-miR-2054	CLIP-seq
MIRT1180876	hsa-miR-20a	CLIP-seq
MIRT1180877	hsa-miR-20b	CLIP-seq
MIRT1180930	hsa-miR-21	CLIP-seq
MIRT1180889	hsa-miR-380	CLIP-seq
MIRT1180931	hsa-miR-3974	CLIP-seq
MIRT1180932	hsa-miR-4477b	CLIP-seq
MIRT1180899	hsa-miR-4661-5p	CLIP-seq
MIRT1180933	hsa-miR-4789-3p	CLIP-seq
MIRT1180934	hsa-miR-513a-3p	CLIP-seq
MIRT1180912	hsa-miR-519a	CLIP-seq
MIRT1180913	hsa-miR-519d	CLIP-seq
MIRT1180935	hsa-miR-548n	CLIP-seq
MIRT1180922	hsa-miR-548t	CLIP-seq
MIRT1180936	hsa-miR-590-5p	CLIP-seq
MIRT1180926	hsa-miR-93	CLIP-seq
MIRT1180927	hsa-miR-96	CLIP-seq
MIRT2052301	hsa-miR-105	CLIP-seq
MIRT2052302	hsa-miR-1245b-5p	CLIP-seq
MIRT2052303	hsa-miR-3142	CLIP-seq
MIRT1180889	hsa-miR-380	CLIP-seq
MIRT1180902	hsa-miR-4724-5p	CLIP-seq
MIRT2052304	hsa-miR-603	CLIP-seq
MIRT2052305	hsa-miR-642b	CLIP-seq
MIRT2052306	hsa-miR-3200-5p	CLIP-seq
MIRT2052301	hsa-miR-105	CLIP-seq
MIRT1180863	hsa-miR-106a	CLIP-seq
MIRT1180864	hsa-miR-106b	CLIP-seq
MIRT2281709	hsa-miR-143	CLIP-seq
MIRT1180871	hsa-miR-17	CLIP-seq
MIRT2281710	hsa-miR-194	CLIP-seq
MIRT1180876	hsa-miR-20a	CLIP-seq
MIRT1180877	hsa-miR-20b	CLIP-seq
MIRT1180879	hsa-miR-299-3p	CLIP-seq
MIRT1180882	hsa-miR-3156-5p	CLIP-seq
MIRT1180884	hsa-miR-323-3p	CLIP-seq
MIRT1180885	hsa-miR-338-5p	CLIP-seq
MIRT1180887	hsa-miR-3692	CLIP-seq
MIRT1180889	hsa-miR-380	CLIP-seq
MIRT2281711	hsa-miR-3942-5p	CLIP-seq
MIRT2281712	hsa-miR-3976	CLIP-seq
MIRT2281713	hsa-miR-4300	CLIP-seq
MIRT1180892	hsa-miR-4427	CLIP-seq
MIRT1180893	hsa-miR-4436b-5p	CLIP-seq
MIRT1180895	hsa-miR-4491	CLIP-seq
MIRT1180897	hsa-miR-4536	CLIP-seq
MIRT2281714	hsa-miR-4633-3p	CLIP-seq
MIRT1180898	hsa-miR-4657	CLIP-seq
MIRT2281715	hsa-miR-4703-5p	CLIP-seq
MIRT1180902	hsa-miR-4724-5p	CLIP-seq
MIRT2281716	hsa-miR-4770	CLIP-seq
MIRT1180906	hsa-miR-486-5p	CLIP-seq
MIRT1180907	hsa-miR-488	CLIP-seq
MIRT1180908	hsa-miR-494	CLIP-seq
MIRT2281717	hsa-miR-514	CLIP-seq
MIRT2281718	hsa-miR-514b-3p	CLIP-seq
MIRT1180911	hsa-miR-518a-5p	CLIP-seq
MIRT1180912	hsa-miR-519a	CLIP-seq
MIRT1180913	hsa-miR-519d	CLIP-seq
MIRT1180915	hsa-miR-527	CLIP-seq
MIRT2281719	hsa-miR-548aa	CLIP-seq
MIRT1180922	hsa-miR-548t	CLIP-seq
MIRT2281720	hsa-miR-587	CLIP-seq
MIRT2052304	hsa-miR-603	CLIP-seq
MIRT2052305	hsa-miR-642b	CLIP-seq
MIRT2281721	hsa-miR-920	CLIP-seq
MIRT1180926	hsa-miR-93	CLIP-seq
MIRT2281722	hsa-miR-944	CLIP-seq
MIRT1180868	hsa-miR-144	CLIP-seq
MIRT2438972	hsa-miR-146b-3p	CLIP-seq
MIRT2438973	hsa-miR-3173-5p	CLIP-seq
MIRT2438974	hsa-miR-3612	CLIP-seq
MIRT2438975	hsa-miR-4254	CLIP-seq
MIRT2438976	hsa-miR-4308	CLIP-seq
MIRT2438977	hsa-miR-4443	CLIP-seq
MIRT2438978	hsa-miR-485-5p	CLIP-seq
MIRT2438979	hsa-miR-604	CLIP-seq
MIRT2438980	hsa-miR-650	CLIP-seq
MIRT2438981	hsa-miR-874	CLIP-seq
MIRT2281713	hsa-miR-4300	CLIP-seq
MIRT2281714	hsa-miR-4633-3p	CLIP-seq
MIRT2281719	hsa-miR-548aa	CLIP-seq
MIRT2281721	hsa-miR-920	CLIP-seq
MIRT2281713	hsa-miR-4300	CLIP-seq
MIRT2281714	hsa-miR-4633-3p	CLIP-seq
MIRT2281719	hsa-miR-548aa	CLIP-seq
MIRT2281721	hsa-miR-920	CLIP-seq
MIRT2579908	hsa-miR-1257	CLIP-seq
MIRT1180875	hsa-miR-203	CLIP-seq
MIRT2579909	hsa-miR-3609	CLIP-seq
MIRT2579910	hsa-miR-548ah	CLIP-seq
MIRT2579908	hsa-miR-1257	CLIP-seq
MIRT1180875	hsa-miR-203	CLIP-seq
MIRT2579909	hsa-miR-3609	CLIP-seq
MIRT2579910	hsa-miR-548ah	CLIP-seq

Show/Hide all(12)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	32814053
GO:0014069	Component	Postsynaptic density	IBA
GO:0014069	Component	Postsynaptic density	IEA
GO:0016020	Component	Membrane	IEA
GO:0035255	Function	Ionotropic glutamate receptor binding	IBA
GO:0035255	Function	Ionotropic glutamate receptor binding	IEA
GO:0045202	Component	Synapse	IEA
GO:0098696	Process	Regulation of neurotransmitter receptor localization to postsynaptic specialization membrane	IEA
GO:0098839	Component	Postsynaptic density membrane	IEA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0099645	Process	Neurotransmitter receptor localization to postsynaptic specialization membrane	IEA

MIM	HGNC	e!Ensembl
607974	14644	ENSG00000171208

Protein

UniProt ID

Q8NC67

Protein name

Neuropilin and tolloid-like protein 2 (Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2)

Protein function

Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasin

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00431	CUB	45 → 156	CUB domain	Domain
PF00431	CUB	177 → 289	CUB domain	Domain
PF00057	Ldl_recept_a	295 → 331	Low-density lipoprotein receptor domain class A	Repeat

Sequence

MALERLCSVLKVLLITVLVVEGIAVAQKTQDGQNIGIKHIPATQCGIWVRTSNGGHFASP
NYPDSYPPNKECIYILEAAPRQRIELTFDEHYYIEPSFECRFDHLEVRDGPFGFSPLIDR
YCGVKSPPLIRSTGRFMWIKFSSDEELEGLGFRAKYSFIPDPDFTYLGGILNPIPDCQFE
LSGADGIVRSSQVEQEEKTKPGQAVDCIWTIKATPKAKIYLRFLDYQMEHSNECKRNFVA
VYDGSSSIENLKAKFCSTVANDVMLKTGIGVIRMWADEGSRLSRFRMLFTSFVEPPCTSS
TFFCHSNMCINNSLVCNGVQNCAYPWDENHCKEKKKAGVFEQITKTHGTIIGITSGIVLV
LLIISILVQVKQPRKKVMACKTAFNKTGFQEVFDPPHYELFSLRDKEISADLADLSEELD
NYQKMRRSSTASRCIHDHHCGSQASSVKQSRTNLSSMELPFRNDFAQPQPMKTFNSTFKK
SSYTFKQGHECPEQALEDRVMEEIPCEIYVRGREDSAQASISIDF

Sequence length

525

Interactions

View interactions

NETO2 (neuropilin and tolloid like 2)