RNF170 (ring finger protein 170)

Gene

• Entrez ID: 81790
• Gene name: Ring finger protein 170
• Gene symbol: RNF170
• Synonyms (NCBI Gene): ADSA, SNAX1, SPG85
• Chromosome: 8
• Chromosome location: 8p11.21
• Summary: This gene encodes a RING domain-containing protein that resides in the endoplasmic reticulum (ER) membrane. This protein functions as an E3 ubiquitin ligase and mediates ubiquitination and processing of inositol 1,4,5-trisphosphate (IP3) receptors via the

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs397514478	G>A	Pathogenic	Coding sequence variant, missense variant, intron variant, non coding transcript variant
rs587780441	T>C	Likely-pathogenic	Missense variant, non coding transcript variant, coding sequence variant, intron variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT021592	hsa-miR-142-3p	Microarray	17612493
MIRT023233	hsa-miR-122-5p	Microarray	17612493
MIRT040795	hsa-miR-18a-3p	CLASH	23622248
MIRT666530	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT666529	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT666528	hsa-miR-5693	HITS-CLIP	23824327
MIRT666527	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT666526	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT666525	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT666524	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT666523	hsa-miR-1267	HITS-CLIP	23824327
MIRT666522	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT666521	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT666520	hsa-miR-3135b	HITS-CLIP	23824327
MIRT666519	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT023233	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT666518	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT666517	hsa-miR-3652	HITS-CLIP	23824327
MIRT666516	hsa-miR-4430	HITS-CLIP	23824327
MIRT666515	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT666514	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT666513	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT666512	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT666511	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT666510	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT666509	hsa-miR-5698	HITS-CLIP	23824327
MIRT439761	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT439761	hsa-miR-218-5p	HITS-CLIP	23212916
MIRT666530	hsa-miR-3664-5p	HITS-CLIP	23824327
MIRT666529	hsa-miR-1306-5p	HITS-CLIP	23824327
MIRT666528	hsa-miR-5693	HITS-CLIP	23824327
MIRT666527	hsa-miR-660-3p	HITS-CLIP	23824327
MIRT666526	hsa-miR-939-3p	HITS-CLIP	23824327
MIRT666525	hsa-miR-6852-5p	HITS-CLIP	23824327
MIRT666524	hsa-miR-6742-3p	HITS-CLIP	23824327
MIRT666523	hsa-miR-1267	HITS-CLIP	23824327
MIRT666522	hsa-miR-367-5p	HITS-CLIP	23824327
MIRT666521	hsa-miR-6499-3p	HITS-CLIP	23824327
MIRT666520	hsa-miR-3135b	HITS-CLIP	23824327
MIRT666519	hsa-miR-504-3p	HITS-CLIP	23824327
MIRT023233	hsa-miR-122-5p	HITS-CLIP	23824327
MIRT666518	hsa-miR-6722-5p	HITS-CLIP	23824327
MIRT666517	hsa-miR-3652	HITS-CLIP	23824327
MIRT666516	hsa-miR-4430	HITS-CLIP	23824327
MIRT666515	hsa-miR-143-5p	HITS-CLIP	23824327
MIRT666514	hsa-miR-6501-5p	HITS-CLIP	23824327
MIRT666513	hsa-miR-4423-5p	HITS-CLIP	23824327
MIRT666512	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT666511	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT666510	hsa-miR-744-3p	HITS-CLIP	23824327
MIRT666509	hsa-miR-5698	HITS-CLIP	23824327
MIRT1311420	hsa-miR-1273f	CLIP-seq
MIRT1311421	hsa-miR-143	CLIP-seq
MIRT1311422	hsa-miR-146b-3p	CLIP-seq
MIRT1311423	hsa-miR-3173-5p	CLIP-seq
MIRT1311424	hsa-miR-371b-3p	CLIP-seq
MIRT1311425	hsa-miR-3936	CLIP-seq
MIRT1311426	hsa-miR-3944-3p	CLIP-seq
MIRT1311427	hsa-miR-4292	CLIP-seq
MIRT1311428	hsa-miR-4708-5p	CLIP-seq
MIRT1311429	hsa-miR-4728-5p	CLIP-seq
MIRT1311430	hsa-miR-4770	CLIP-seq
MIRT1311431	hsa-miR-555	CLIP-seq
MIRT1311432	hsa-miR-874	CLIP-seq
MIRT1311433	hsa-miR-106a	CLIP-seq
MIRT1311434	hsa-miR-106b	CLIP-seq
MIRT1311435	hsa-miR-129-5p	CLIP-seq
MIRT1311436	hsa-miR-150	CLIP-seq
MIRT1311437	hsa-miR-17	CLIP-seq
MIRT1311438	hsa-miR-20a	CLIP-seq
MIRT1311439	hsa-miR-20b	CLIP-seq
MIRT1311440	hsa-miR-302a	CLIP-seq
MIRT1311441	hsa-miR-302b	CLIP-seq
MIRT1311442	hsa-miR-302c	CLIP-seq
MIRT1311443	hsa-miR-302d	CLIP-seq
MIRT1311444	hsa-miR-302e	CLIP-seq
MIRT1311445	hsa-miR-3159	CLIP-seq
MIRT1311446	hsa-miR-34a	CLIP-seq
MIRT1311447	hsa-miR-34c-5p	CLIP-seq
MIRT1311448	hsa-miR-3667-3p	CLIP-seq
MIRT1311449	hsa-miR-372	CLIP-seq
MIRT1311450	hsa-miR-373	CLIP-seq
MIRT1311451	hsa-miR-4294	CLIP-seq
MIRT1311452	hsa-miR-4302	CLIP-seq
MIRT1311453	hsa-miR-4419a	CLIP-seq
MIRT1311454	hsa-miR-4438	CLIP-seq
MIRT1311455	hsa-miR-4490	CLIP-seq
MIRT1311456	hsa-miR-449a	CLIP-seq
MIRT1311457	hsa-miR-449b	CLIP-seq
MIRT1311458	hsa-miR-4504	CLIP-seq
MIRT1311459	hsa-miR-4510	CLIP-seq
MIRT1311460	hsa-miR-4699-5p	CLIP-seq
MIRT1311461	hsa-miR-4774-5p	CLIP-seq
MIRT1311462	hsa-miR-4802-3p	CLIP-seq
MIRT1311463	hsa-miR-5095	CLIP-seq
MIRT1311464	hsa-miR-519d	CLIP-seq
MIRT1311465	hsa-miR-520a-3p	CLIP-seq
MIRT1311466	hsa-miR-520b	CLIP-seq
MIRT1311467	hsa-miR-520c-3p	CLIP-seq
MIRT1311468	hsa-miR-520d-3p	CLIP-seq
MIRT1311469	hsa-miR-520e	CLIP-seq
MIRT1311470	hsa-miR-520g	CLIP-seq
MIRT1311471	hsa-miR-520h	CLIP-seq
MIRT1311472	hsa-miR-542-3p	CLIP-seq
MIRT1311473	hsa-miR-93	CLIP-seq
MIRT1311474	hsa-miR-1343	CLIP-seq
MIRT1311475	hsa-miR-141	CLIP-seq
MIRT1311476	hsa-miR-200a	CLIP-seq
MIRT1311477	hsa-miR-345	CLIP-seq
MIRT1311446	hsa-miR-34a	CLIP-seq
MIRT1311447	hsa-miR-34c-5p	CLIP-seq
MIRT1311452	hsa-miR-4302	CLIP-seq
MIRT1311455	hsa-miR-4490	CLIP-seq
MIRT1311456	hsa-miR-449a	CLIP-seq
MIRT1311457	hsa-miR-449b	CLIP-seq
MIRT1311458	hsa-miR-4504	CLIP-seq
MIRT1311461	hsa-miR-4774-5p	CLIP-seq
MIRT1311462	hsa-miR-4802-3p	CLIP-seq
MIRT1311472	hsa-miR-542-3p	CLIP-seq
MIRT1311478	hsa-miR-622	CLIP-seq
MIRT2092517	hsa-miR-4677-3p	CLIP-seq
MIRT2092518	hsa-miR-4679	CLIP-seq
MIRT2092519	hsa-miR-4639-3p	CLIP-seq
MIRT2317034	hsa-miR-4659a-3p	CLIP-seq
MIRT2317035	hsa-miR-4659b-3p	CLIP-seq
MIRT2317036	hsa-let-7a	CLIP-seq
MIRT2317037	hsa-let-7b	CLIP-seq
MIRT2317038	hsa-let-7c	CLIP-seq
MIRT2317039	hsa-let-7d	CLIP-seq
MIRT2317040	hsa-let-7e	CLIP-seq
MIRT2317041	hsa-let-7f	CLIP-seq
MIRT2317042	hsa-let-7g	CLIP-seq
MIRT2317043	hsa-let-7i	CLIP-seq
MIRT2317044	hsa-miR-103b	CLIP-seq
MIRT1311433	hsa-miR-106a	CLIP-seq
MIRT1311434	hsa-miR-106b	CLIP-seq
MIRT2317045	hsa-miR-122	CLIP-seq
MIRT2317046	hsa-miR-1294	CLIP-seq
MIRT1311436	hsa-miR-150	CLIP-seq
MIRT2317047	hsa-miR-153	CLIP-seq
MIRT1311437	hsa-miR-17	CLIP-seq
MIRT2317048	hsa-miR-181a	CLIP-seq
MIRT2317049	hsa-miR-181b	CLIP-seq
MIRT2317050	hsa-miR-181c	CLIP-seq
MIRT2317051	hsa-miR-181d	CLIP-seq
MIRT2317052	hsa-miR-202	CLIP-seq
MIRT1311438	hsa-miR-20a	CLIP-seq
MIRT1311439	hsa-miR-20b	CLIP-seq
MIRT1311440	hsa-miR-302a	CLIP-seq
MIRT1311441	hsa-miR-302b	CLIP-seq
MIRT1311442	hsa-miR-302c	CLIP-seq
MIRT1311443	hsa-miR-302d	CLIP-seq
MIRT1311444	hsa-miR-302e	CLIP-seq
MIRT1311445	hsa-miR-3159	CLIP-seq
MIRT2317053	hsa-miR-3163	CLIP-seq
MIRT2317054	hsa-miR-331-5p	CLIP-seq
MIRT1311449	hsa-miR-372	CLIP-seq
MIRT1311450	hsa-miR-373	CLIP-seq
MIRT2317055	hsa-miR-4262	CLIP-seq
MIRT1311451	hsa-miR-4294	CLIP-seq
MIRT2317056	hsa-miR-4316	CLIP-seq
MIRT1311453	hsa-miR-4419a	CLIP-seq
MIRT1311454	hsa-miR-4438	CLIP-seq
MIRT2317057	hsa-miR-4457	CLIP-seq
MIRT2317058	hsa-miR-4458	CLIP-seq
MIRT2317059	hsa-miR-4500	CLIP-seq
MIRT1311459	hsa-miR-4510	CLIP-seq
MIRT2317060	hsa-miR-4540	CLIP-seq
MIRT2092519	hsa-miR-4639-3p	CLIP-seq
MIRT2317034	hsa-miR-4659a-3p	CLIP-seq
MIRT2317035	hsa-miR-4659b-3p	CLIP-seq
MIRT2092517	hsa-miR-4677-3p	CLIP-seq
MIRT2317061	hsa-miR-4678	CLIP-seq
MIRT2092518	hsa-miR-4679	CLIP-seq
MIRT2317062	hsa-miR-4680-3p	CLIP-seq
MIRT2317063	hsa-miR-4686	CLIP-seq
MIRT2317064	hsa-miR-4713-3p	CLIP-seq
MIRT2317065	hsa-miR-4713-5p	CLIP-seq
MIRT2317066	hsa-miR-4715-3p	CLIP-seq
MIRT2317067	hsa-miR-4722-3p	CLIP-seq
MIRT2317068	hsa-miR-4735-5p	CLIP-seq
MIRT2317069	hsa-miR-4763-5p	CLIP-seq
MIRT2317070	hsa-miR-4775	CLIP-seq
MIRT2317071	hsa-miR-4794	CLIP-seq
MIRT2317072	hsa-miR-485-3p	CLIP-seq
MIRT1311463	hsa-miR-5095	CLIP-seq
MIRT1311464	hsa-miR-519d	CLIP-seq
MIRT1311465	hsa-miR-520a-3p	CLIP-seq
MIRT1311466	hsa-miR-520b	CLIP-seq
MIRT1311467	hsa-miR-520c-3p	CLIP-seq
MIRT1311468	hsa-miR-520d-3p	CLIP-seq
MIRT1311469	hsa-miR-520e	CLIP-seq
MIRT1311470	hsa-miR-520g	CLIP-seq
MIRT1311471	hsa-miR-520h	CLIP-seq
MIRT2317073	hsa-miR-532-3p	CLIP-seq
MIRT2317074	hsa-miR-566	CLIP-seq
MIRT2317075	hsa-miR-590-3p	CLIP-seq
MIRT1311473	hsa-miR-93	CLIP-seq
MIRT2317076	hsa-miR-98	CLIP-seq
MIRT2317036	hsa-let-7a	CLIP-seq
MIRT2317037	hsa-let-7b	CLIP-seq
MIRT2317038	hsa-let-7c	CLIP-seq
MIRT2317039	hsa-let-7d	CLIP-seq
MIRT2317040	hsa-let-7e	CLIP-seq
MIRT2317041	hsa-let-7f	CLIP-seq
MIRT2317042	hsa-let-7g	CLIP-seq
MIRT2317043	hsa-let-7i	CLIP-seq
MIRT2317046	hsa-miR-1294	CLIP-seq
MIRT2317052	hsa-miR-202	CLIP-seq
MIRT2317054	hsa-miR-331-5p	CLIP-seq
MIRT2317056	hsa-miR-4316	CLIP-seq
MIRT2317058	hsa-miR-4458	CLIP-seq
MIRT2317059	hsa-miR-4500	CLIP-seq
MIRT2092517	hsa-miR-4677-3p	CLIP-seq
MIRT2317061	hsa-miR-4678	CLIP-seq
MIRT2092518	hsa-miR-4679	CLIP-seq
MIRT2317063	hsa-miR-4686	CLIP-seq
MIRT2317076	hsa-miR-98	CLIP-seq
MIRT2317045	hsa-miR-122	CLIP-seq
MIRT1311435	hsa-miR-129-5p	CLIP-seq
MIRT2458418	hsa-miR-3149	CLIP-seq
MIRT2458419	hsa-miR-3199	CLIP-seq
MIRT2458420	hsa-miR-411	CLIP-seq
MIRT1311451	hsa-miR-4294	CLIP-seq
MIRT1311453	hsa-miR-4419a	CLIP-seq
MIRT1311454	hsa-miR-4438	CLIP-seq
MIRT1311459	hsa-miR-4510	CLIP-seq
MIRT2092519	hsa-miR-4639-3p	CLIP-seq
MIRT2317066	hsa-miR-4715-3p	CLIP-seq
MIRT2317067	hsa-miR-4722-3p	CLIP-seq
MIRT2317068	hsa-miR-4735-5p	CLIP-seq
MIRT2317069	hsa-miR-4763-5p	CLIP-seq
MIRT2317070	hsa-miR-4775	CLIP-seq
MIRT2317071	hsa-miR-4794	CLIP-seq
MIRT2458421	hsa-miR-483-5p	CLIP-seq
MIRT1311463	hsa-miR-5095	CLIP-seq
MIRT2317074	hsa-miR-566	CLIP-seq
MIRT2317075	hsa-miR-590-3p	CLIP-seq
MIRT2458422	hsa-miR-595	CLIP-seq
MIRT2458423	hsa-miR-628-5p	CLIP-seq
MIRT2458424	hsa-miR-648	CLIP-seq
MIRT1311433	hsa-miR-106a	CLIP-seq
MIRT1311434	hsa-miR-106b	CLIP-seq
MIRT2612876	hsa-miR-1193	CLIP-seq
MIRT2612877	hsa-miR-1208	CLIP-seq
MIRT2317045	hsa-miR-122	CLIP-seq
MIRT2612878	hsa-miR-1237	CLIP-seq
MIRT2612879	hsa-miR-1248	CLIP-seq
MIRT1311420	hsa-miR-1273f	CLIP-seq
MIRT2612880	hsa-miR-1284	CLIP-seq
MIRT2612881	hsa-miR-1285	CLIP-seq
MIRT1311435	hsa-miR-129-5p	CLIP-seq
MIRT1311474	hsa-miR-1343	CLIP-seq
MIRT1311421	hsa-miR-143	CLIP-seq
MIRT1311436	hsa-miR-150	CLIP-seq
MIRT1311437	hsa-miR-17	CLIP-seq
MIRT2612882	hsa-miR-188-5p	CLIP-seq
MIRT2612883	hsa-miR-197	CLIP-seq
MIRT2612884	hsa-miR-1976	CLIP-seq
MIRT2612885	hsa-miR-204	CLIP-seq
MIRT1311438	hsa-miR-20a	CLIP-seq
MIRT1311439	hsa-miR-20b	CLIP-seq
MIRT2612886	hsa-miR-211	CLIP-seq
MIRT2612887	hsa-miR-2110	CLIP-seq
MIRT2612888	hsa-miR-22	CLIP-seq
MIRT2612889	hsa-miR-2355-3p	CLIP-seq
MIRT2612890	hsa-miR-2355-5p	CLIP-seq
MIRT2612891	hsa-miR-2392	CLIP-seq
MIRT1311440	hsa-miR-302a	CLIP-seq
MIRT1311441	hsa-miR-302b	CLIP-seq
MIRT1311442	hsa-miR-302c	CLIP-seq
MIRT1311443	hsa-miR-302d	CLIP-seq
MIRT1311444	hsa-miR-302e	CLIP-seq
MIRT2612892	hsa-miR-3117-5p	CLIP-seq
MIRT2612893	hsa-miR-3145-3p	CLIP-seq
MIRT2458418	hsa-miR-3149	CLIP-seq
MIRT1311445	hsa-miR-3159	CLIP-seq
MIRT2317053	hsa-miR-3163	CLIP-seq
MIRT2612894	hsa-miR-3182	CLIP-seq
MIRT2612895	hsa-miR-3187-5p	CLIP-seq
MIRT2458419	hsa-miR-3199	CLIP-seq
MIRT2612896	hsa-miR-323-3p	CLIP-seq
MIRT2612897	hsa-miR-324-5p	CLIP-seq
MIRT2612898	hsa-miR-338-5p	CLIP-seq
MIRT2612899	hsa-miR-3614-5p	CLIP-seq
MIRT2612900	hsa-miR-3679-3p	CLIP-seq
MIRT2612901	hsa-miR-370	CLIP-seq
MIRT1311449	hsa-miR-372	CLIP-seq
MIRT1311450	hsa-miR-373	CLIP-seq
MIRT2612902	hsa-miR-3945	CLIP-seq
MIRT2612903	hsa-miR-410	CLIP-seq
MIRT2458420	hsa-miR-411	CLIP-seq
MIRT2612904	hsa-miR-4251	CLIP-seq
MIRT2612905	hsa-miR-4253	CLIP-seq
MIRT2612906	hsa-miR-4268	CLIP-seq
MIRT2612907	hsa-miR-4271	CLIP-seq
MIRT2612908	hsa-miR-4282	CLIP-seq
MIRT2612909	hsa-miR-4286	CLIP-seq
MIRT1311451	hsa-miR-4294	CLIP-seq
MIRT2612910	hsa-miR-4303	CLIP-seq
MIRT2612911	hsa-miR-4314	CLIP-seq
MIRT2612912	hsa-miR-432	CLIP-seq
MIRT2612913	hsa-miR-4329	CLIP-seq
MIRT2612914	hsa-miR-4330	CLIP-seq
MIRT1311453	hsa-miR-4419a	CLIP-seq
MIRT2612915	hsa-miR-4422	CLIP-seq
MIRT1311454	hsa-miR-4438	CLIP-seq
MIRT2612916	hsa-miR-4446-5p	CLIP-seq
MIRT2612917	hsa-miR-4448	CLIP-seq
MIRT2612918	hsa-miR-4468	CLIP-seq
MIRT2612919	hsa-miR-4509	CLIP-seq
MIRT1311459	hsa-miR-4510	CLIP-seq
MIRT2612920	hsa-miR-4522	CLIP-seq
MIRT2092519	hsa-miR-4639-3p	CLIP-seq
MIRT2612921	hsa-miR-4645-3p	CLIP-seq
MIRT2612922	hsa-miR-4646-3p	CLIP-seq
MIRT2612923	hsa-miR-4652-3p	CLIP-seq
MIRT2612924	hsa-miR-4659a-5p	CLIP-seq
MIRT2612925	hsa-miR-4659b-5p	CLIP-seq
MIRT2612926	hsa-miR-4662a-5p	CLIP-seq
MIRT2612927	hsa-miR-4667-5p	CLIP-seq
MIRT2612928	hsa-miR-4668-3p	CLIP-seq
MIRT2612929	hsa-miR-4668-5p	CLIP-seq
MIRT2612930	hsa-miR-4676-5p	CLIP-seq
MIRT2317063	hsa-miR-4686	CLIP-seq
MIRT2612931	hsa-miR-4695-3p	CLIP-seq
MIRT2612932	hsa-miR-4700-5p	CLIP-seq
MIRT1311428	hsa-miR-4708-5p	CLIP-seq
MIRT2317066	hsa-miR-4715-3p	CLIP-seq
MIRT2612933	hsa-miR-4716-5p	CLIP-seq
MIRT2317067	hsa-miR-4722-3p	CLIP-seq
MIRT2612934	hsa-miR-4725-3p	CLIP-seq
MIRT2612935	hsa-miR-4727-3p	CLIP-seq
MIRT2612936	hsa-miR-4729	CLIP-seq
MIRT2317068	hsa-miR-4735-5p	CLIP-seq
MIRT2612937	hsa-miR-4744	CLIP-seq
MIRT2317069	hsa-miR-4763-5p	CLIP-seq
MIRT1311430	hsa-miR-4770	CLIP-seq
MIRT2612938	hsa-miR-4773	CLIP-seq
MIRT2317070	hsa-miR-4775	CLIP-seq
MIRT2612939	hsa-miR-4793-5p	CLIP-seq
MIRT2317071	hsa-miR-4794	CLIP-seq
MIRT2612940	hsa-miR-4795-3p	CLIP-seq
MIRT2458421	hsa-miR-483-5p	CLIP-seq
MIRT2612941	hsa-miR-495	CLIP-seq
MIRT1311463	hsa-miR-5095	CLIP-seq
MIRT2612942	hsa-miR-5096	CLIP-seq
MIRT2612943	hsa-miR-513b	CLIP-seq
MIRT1311464	hsa-miR-519d	CLIP-seq
MIRT1311465	hsa-miR-520a-3p	CLIP-seq
MIRT1311466	hsa-miR-520b	CLIP-seq
MIRT1311467	hsa-miR-520c-3p	CLIP-seq
MIRT1311468	hsa-miR-520d-3p	CLIP-seq
MIRT1311469	hsa-miR-520e	CLIP-seq
MIRT1311470	hsa-miR-520g	CLIP-seq
MIRT1311471	hsa-miR-520h	CLIP-seq
MIRT2612944	hsa-miR-548ac	CLIP-seq
MIRT2612945	hsa-miR-548ae	CLIP-seq
MIRT2612946	hsa-miR-548aj	CLIP-seq
MIRT2612947	hsa-miR-548am	CLIP-seq
MIRT2612948	hsa-miR-548c-3p	CLIP-seq
MIRT2612949	hsa-miR-548d-3p	CLIP-seq
MIRT2612950	hsa-miR-548x	CLIP-seq
MIRT2612951	hsa-miR-548z	CLIP-seq
MIRT2612952	hsa-miR-549	CLIP-seq
MIRT2612953	hsa-miR-558	CLIP-seq
MIRT2612954	hsa-miR-561	CLIP-seq
MIRT2317074	hsa-miR-566	CLIP-seq
MIRT2612955	hsa-miR-575	CLIP-seq
MIRT2317075	hsa-miR-590-3p	CLIP-seq
MIRT2612956	hsa-miR-612	CLIP-seq
MIRT2612957	hsa-miR-628-3p	CLIP-seq
MIRT2612958	hsa-miR-637	CLIP-seq
MIRT2612959	hsa-miR-767-3p	CLIP-seq
MIRT2612960	hsa-miR-890	CLIP-seq
MIRT1311473	hsa-miR-93	CLIP-seq
MIRT1311433	hsa-miR-106a	CLIP-seq
MIRT1311434	hsa-miR-106b	CLIP-seq
MIRT2612876	hsa-miR-1193	CLIP-seq
MIRT2612877	hsa-miR-1208	CLIP-seq
MIRT2317045	hsa-miR-122	CLIP-seq
MIRT2612878	hsa-miR-1237	CLIP-seq
MIRT2612879	hsa-miR-1248	CLIP-seq
MIRT1311420	hsa-miR-1273f	CLIP-seq
MIRT2612880	hsa-miR-1284	CLIP-seq
MIRT2612881	hsa-miR-1285	CLIP-seq
MIRT1311435	hsa-miR-129-5p	CLIP-seq
MIRT1311474	hsa-miR-1343	CLIP-seq
MIRT1311421	hsa-miR-143	CLIP-seq
MIRT1311436	hsa-miR-150	CLIP-seq
MIRT1311437	hsa-miR-17	CLIP-seq
MIRT2612882	hsa-miR-188-5p	CLIP-seq
MIRT2612883	hsa-miR-197	CLIP-seq
MIRT2612884	hsa-miR-1976	CLIP-seq
MIRT1311438	hsa-miR-20a	CLIP-seq
MIRT1311439	hsa-miR-20b	CLIP-seq
MIRT2612890	hsa-miR-2355-5p	CLIP-seq
MIRT2612891	hsa-miR-2392	CLIP-seq
MIRT1311440	hsa-miR-302a	CLIP-seq
MIRT1311441	hsa-miR-302b	CLIP-seq
MIRT1311442	hsa-miR-302c	CLIP-seq
MIRT1311443	hsa-miR-302d	CLIP-seq
MIRT1311444	hsa-miR-302e	CLIP-seq
MIRT2612892	hsa-miR-3117-5p	CLIP-seq
MIRT2612893	hsa-miR-3145-3p	CLIP-seq
MIRT2458418	hsa-miR-3149	CLIP-seq
MIRT1311445	hsa-miR-3159	CLIP-seq
MIRT2317053	hsa-miR-3163	CLIP-seq
MIRT2612894	hsa-miR-3182	CLIP-seq
MIRT2612895	hsa-miR-3187-5p	CLIP-seq
MIRT2458419	hsa-miR-3199	CLIP-seq
MIRT2612896	hsa-miR-323-3p	CLIP-seq
MIRT2612897	hsa-miR-324-5p	CLIP-seq
MIRT2612898	hsa-miR-338-5p	CLIP-seq
MIRT2689835	hsa-miR-3613-3p	CLIP-seq
MIRT2689836	hsa-miR-361-3p	CLIP-seq
MIRT2612899	hsa-miR-3614-5p	CLIP-seq
MIRT2689837	hsa-miR-3662	CLIP-seq
MIRT2612900	hsa-miR-3679-3p	CLIP-seq
MIRT1311449	hsa-miR-372	CLIP-seq
MIRT1311450	hsa-miR-373	CLIP-seq
MIRT2689838	hsa-miR-3913-3p	CLIP-seq
MIRT2689839	hsa-miR-3919	CLIP-seq
MIRT2612902	hsa-miR-3945	CLIP-seq
MIRT2458420	hsa-miR-411	CLIP-seq
MIRT2612904	hsa-miR-4251	CLIP-seq
MIRT2612905	hsa-miR-4253	CLIP-seq
MIRT2612909	hsa-miR-4286	CLIP-seq
MIRT1311451	hsa-miR-4294	CLIP-seq
MIRT2612910	hsa-miR-4303	CLIP-seq
MIRT2612912	hsa-miR-432	CLIP-seq
MIRT2612913	hsa-miR-4329	CLIP-seq
MIRT2612914	hsa-miR-4330	CLIP-seq
MIRT1311453	hsa-miR-4419a	CLIP-seq
MIRT2689840	hsa-miR-4421	CLIP-seq
MIRT1311454	hsa-miR-4438	CLIP-seq
MIRT2612916	hsa-miR-4446-5p	CLIP-seq
MIRT2612918	hsa-miR-4468	CLIP-seq
MIRT2612919	hsa-miR-4509	CLIP-seq
MIRT1311459	hsa-miR-4510	CLIP-seq
MIRT2612920	hsa-miR-4522	CLIP-seq
MIRT2092519	hsa-miR-4639-3p	CLIP-seq
MIRT2612921	hsa-miR-4645-3p	CLIP-seq
MIRT2612923	hsa-miR-4652-3p	CLIP-seq
MIRT2612924	hsa-miR-4659a-5p	CLIP-seq
MIRT2612925	hsa-miR-4659b-5p	CLIP-seq
MIRT2612926	hsa-miR-4662a-5p	CLIP-seq
MIRT2612928	hsa-miR-4668-3p	CLIP-seq
MIRT2612930	hsa-miR-4676-5p	CLIP-seq
MIRT2612931	hsa-miR-4695-3p	CLIP-seq
MIRT1311428	hsa-miR-4708-5p	CLIP-seq
MIRT2317066	hsa-miR-4715-3p	CLIP-seq
MIRT2612933	hsa-miR-4716-5p	CLIP-seq
MIRT2317067	hsa-miR-4722-3p	CLIP-seq
MIRT2612935	hsa-miR-4727-3p	CLIP-seq
MIRT2612936	hsa-miR-4729	CLIP-seq
MIRT2317068	hsa-miR-4735-5p	CLIP-seq
MIRT2612937	hsa-miR-4744	CLIP-seq
MIRT2689841	hsa-miR-4756-3p	CLIP-seq
MIRT2317069	hsa-miR-4763-5p	CLIP-seq
MIRT1311430	hsa-miR-4770	CLIP-seq
MIRT2612938	hsa-miR-4773	CLIP-seq
MIRT2317070	hsa-miR-4775	CLIP-seq
MIRT2612939	hsa-miR-4793-5p	CLIP-seq
MIRT2317071	hsa-miR-4794	CLIP-seq
MIRT2458421	hsa-miR-483-5p	CLIP-seq
MIRT2689842	hsa-miR-489	CLIP-seq
MIRT2689843	hsa-miR-499-3p	CLIP-seq
MIRT2689844	hsa-miR-499a-3p	CLIP-seq
MIRT1311463	hsa-miR-5095	CLIP-seq
MIRT2612942	hsa-miR-5096	CLIP-seq
MIRT2612943	hsa-miR-513b	CLIP-seq
MIRT1311464	hsa-miR-519d	CLIP-seq
MIRT1311465	hsa-miR-520a-3p	CLIP-seq
MIRT1311466	hsa-miR-520b	CLIP-seq
MIRT1311467	hsa-miR-520c-3p	CLIP-seq
MIRT1311468	hsa-miR-520d-3p	CLIP-seq
MIRT1311469	hsa-miR-520e	CLIP-seq
MIRT1311470	hsa-miR-520g	CLIP-seq
MIRT1311471	hsa-miR-520h	CLIP-seq
MIRT2689845	hsa-miR-544	CLIP-seq
MIRT2612944	hsa-miR-548ac	CLIP-seq
MIRT2612945	hsa-miR-548ae	CLIP-seq
MIRT2612946	hsa-miR-548aj	CLIP-seq
MIRT2612947	hsa-miR-548am	CLIP-seq
MIRT2612949	hsa-miR-548d-3p	CLIP-seq
MIRT2612950	hsa-miR-548x	CLIP-seq
MIRT2612951	hsa-miR-548z	CLIP-seq
MIRT2612952	hsa-miR-549	CLIP-seq
MIRT2612954	hsa-miR-561	CLIP-seq
MIRT2317074	hsa-miR-566	CLIP-seq
MIRT2612955	hsa-miR-575	CLIP-seq
MIRT2317075	hsa-miR-590-3p	CLIP-seq
MIRT2612956	hsa-miR-612	CLIP-seq
MIRT2612957	hsa-miR-628-3p	CLIP-seq
MIRT2612960	hsa-miR-890	CLIP-seq
MIRT1311473	hsa-miR-93	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000209	Process	Protein polyubiquitination	IEA
GO:0005515	Function	Protein binding	IPI	25416956, 32296183
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005789	Component	Endoplasmic reticulum membrane	IEA
GO:0007628	Process	Adult walking behavior	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0009266	Process	Response to temperature stimulus	IEA
GO:0010467	Process	Gene expression	IEA
GO:0010498	Process	Proteasomal protein catabolic process	IEA
GO:0014823	Process	Response to activity	IEA
GO:0016020	Component	Membrane	IEA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0016740	Function	Transferase activity	IEA
GO:0030163	Process	Protein catabolic process	IEA
GO:0034138	Process	Toll-like receptor 3 signaling pathway	IEA
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IEA
GO:0045087	Process	Innate immune response	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0061630	Function	Ubiquitin protein ligase activity	IEA
GO:0070936	Process	Protein K48-linked ubiquitination	IEA
GO:0090659	Process	Walking behavior	IEA

Other IDs

• MIM: 614649
• HGNC: 25358
• e!Ensembl: ENSG00000120925

Protein

• UniProt ID: Q96K19
• Protein name: E3 ubiquitin-protein ligase RNF170 (EC 2.3.2.27) (Putative LAG1-interacting protein) (RING finger protein 170) (RING-type E3 ubiquitin transferase RNF170)
• Protein function: E3 ubiquitin-protein ligase that plays an essential role in stimulus-induced inositol 1,4,5-trisphosphate receptor type 1 (ITPR1) ubiquitination and degradation via the endoplasmic reticulum-associated degradation (ERAD) pathway. Also involved i
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF00097	zf-C3HC4	87 → 129	Zinc finger, C3HC4 type (RING finger)	Domain
  PF06803	DUF1232	202 → 239	Protein of unknown function (DUF1232)	Family

• Tissue specificity: TISSUE SPECIFICITY: Expressed in the spinal cord. {ECO:0000269|PubMed:21115467}.
• Sequence:

  MAKYQGEVQSLKLDDDSVIEGVSDQVLVAVVVSFALIATLVYALFRNVHQNIHPENQELV
  RVLREQLQTEQDAPAATRQQFYTDMYCPICLHQASFPVETNCGHLFCGACIIAYWRYGSW
  LGAISCPICRQTVTLLLTVFGEDDQSQDVLRLHQDINDYNRRFSGQPRSIMERIMDLPTL
  LRHAFREMFSVGGLFWMFRIRIILCLMGAFFYLISPLDFVPEALFGILGFLDDFFVIFLL
  LIYISIMYREVITQRLTR

• Sequence length: 258

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Autosomal dominant sensory ataxia 1	Pathogenic	rs397514478	RCV000024296
Neurodevelopmental disorder	Pathogenic	rs2128929811	RCV001780019
Spastic paraplegia	Likely pathogenic	rs1159600703	RCV001849523
Spastic paraplegia 85, autosomal recessive	Likely pathogenic; Pathogenic	rs1159600703, rs2128922898, rs2128934252, rs397514478	RCV001806233 RCV001804215 RCV002255107 RCV003226168

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
RNF170-related disorder	Uncertain significance; Likely benign	rs1476458814, rs148611952	RCV003402284 RCV003939054

Associations from Text Mining
Disease Name	Relationship Type	References
Ataxia	Associate	34469621
Ataxia Sensory Autosomal Dominant	Associate	34469621
Metabolic Syndrome	Associate	37138862
Neurodegenerative Diseases	Associate	31874412
Osteoarthritis	Associate	37138862
Pallidopyramidal syndrome	Associate	34469621
Spastic Paraplegia Hereditary	Associate	31874412, 34469621