APOLD1 (apolipoprotein L domain containing 1)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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81575 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Apolipoprotein L domain containing 1 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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APOLD1 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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BDVAS, VERGE |
Disease Acronyms (UniProt)
Disease acronyms from UniProt database
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BDVAS |
Chromosome
Chromosome number
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12 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12p13.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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APOLD1 is an endothelial cell early response protein that may play a role in regulation of endothelial cell signaling and vascular function (Regard et al., 2004 [PubMed 15102925]).[supplied by OMIM, Dec 2008] |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q96LR9 | ||||||||||
Protein name | Apolipoprotein L domain-containing protein 1 (Vascular early response gene protein) | ||||||||||
Protein function | Is a modulator of endothelial barrier permeability, required for proper organization of endothelial cell-cell junctions and cytoskeleton (PubMed:35638551). It also plays a role in the modulation of secretory autophagy (PubMed:35638551). May affe | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: Expressed in neonatal dermal microvascular endothelial cells. {ECO:0000269|PubMed:15102925}. | ||||||||||
Sequence |
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Sequence length | 279 | ||||||||||
Interactions | View interactions |
Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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