ILKAP (ILK associated serine/threonine phosphatase)

Gene Gene information from NCBI Gene database.
Gene miRNA Gene ontology Other IDs Protein
Entrez ID 80895
Gene name ILK associated serine/threonine phosphatase
Gene symbol ILKAP
Synonyms (NCBI Gene)
ILKAP2ILKAP3PP2C-DELTAPP2CDPPM1O
Chromosome 2
Chromosome location 2q37.3
Summary The protein encoded by this gene is a protein serine/threonine phosphatase of the PP2C family. This protein can interact with integrin-linked kinase (ILK/ILK1), a regulator of integrin mediated signaling, and regulate the kinase activity of ILK. Through t
miRNA miRNA information provided by mirtarbase database.
2
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all (2)
miRTarBase ID miRNA Experiments Reference
MIRT052596 hsa-let-7a-5p CLASH 23622248
MIRT037443 hsa-miR-744-5p CLASH 23622248
Gene ontology (GO) Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
9
Gene miRNA Gene ontology Other IDs Protein
Show/Hide all (9)
GO ID Ontology Definition Evidence Reference
GO:0004721 Function Phosphoprotein phosphatase activity IEA
GO:0004722 Function Protein serine/threonine phosphatase activity IBA
GO:0004722 Function Protein serine/threonine phosphatase activity IEA
GO:0005515 Function Protein binding IPI 11331582, 32814053
GO:0005737 Component Cytoplasm IEA
Other IDs Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
Gene miRNA Gene ontology Other IDs Protein
MIM HGNC e!Ensembl
618909 15566 ENSG00000132323
Protein Protein information from UniProt database.
Gene miRNA Gene ontology Other IDs Protein
UniProt ID Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
Q9H0C8
Protein name Integrin-linked kinase-associated serine/threonine phosphatase 2C (ILKAP) (EC 3.1.3.16)
Protein function Protein phosphatase that may play a role in regulation of cell cycle progression via dephosphorylation of its substrates whose appropriate phosphorylation states might be crucial for cell proliferation. Selectively associates with integrin linke
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00481 PP2C 107 → 383 Protein phosphatase 2C Family
Tissue specificity TISSUE SPECIFICITY: Widely expressed. Highest levels expressed in striated muscle. Much lower levels evident in various smooth muscle tissues. {ECO:0000269|PubMed:11331582}.
Sequence
Sequence length 392
Interactions View interactions