DUSP16 (dual specificity phosphatase 16)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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80824 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Dual specificity phosphatase 16 |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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DUSP16 |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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MKP-7, MKP7 |
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Chromosome
Chromosome number
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12 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12p13.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphoty |
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q9BY84 | |||||||||||||||
| Protein name | Dual specificity protein phosphatase 16 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7) | |||||||||||||||
| Protein function | Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2. | |||||||||||||||
| PDB | 2VSW , 3TG3 , 4YR8 | |||||||||||||||
| Family and domains |
Pfam
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| Sequence |
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| Sequence length | 665 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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