DUSP16 (dual specificity phosphatase 16)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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80824 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Dual specificity phosphatase 16 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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DUSP16 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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MKP-7, MKP7 |
Chromosome
Chromosome number
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12 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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12p13.2 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a mitogen-activated protein kinase phosphatase that is a member of the dual specificity protein phosphatase subfamily. These phosphatases inactivate their target kinases by dephosphorylating both the phosphoserine/threonine and phosphoty |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | ||||||||||||||||
UniProt ID | Q9BY84 | |||||||||||||||
Protein name | Dual specificity protein phosphatase 16 (EC 3.1.3.16) (EC 3.1.3.48) (Mitogen-activated protein kinase phosphatase 7) (MAP kinase phosphatase 7) (MKP-7) | |||||||||||||||
Protein function | Dual specificity protein phosphatase involved in the inactivation of MAP kinases. Dephosphorylates MAPK10 bound to ARRB2. | |||||||||||||||
PDB | 2VSW , 3TG3 , 4YR8 | |||||||||||||||
Family and domains |
Pfam
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Sequence |
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Sequence length | 665 | |||||||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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