Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	79893
Gene name Gene Name - the full gene name approved by the HGNC.	Gametogenetin binding protein 2
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	GGNBP2
Synonyms (NCBI Gene) Gene synonyms aliases	DIF-3, DIF3, LCRG1, LZK1, ZFP403, ZNF403
Chromosome Chromosome number	17
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	17q12

Show/Hide all(58)

miRTarBase ID	miRNA	Experiments
MIRT1018157	hsa-miR-1273f	CLIP-seq
MIRT1018158	hsa-miR-129-5p	CLIP-seq
MIRT1018159	hsa-miR-135a	CLIP-seq
MIRT1018160	hsa-miR-135b	CLIP-seq
MIRT1018161	hsa-miR-199a-3p	CLIP-seq
MIRT1018162	hsa-miR-199b-3p	CLIP-seq
MIRT1018163	hsa-miR-3064-3p	CLIP-seq
MIRT1018164	hsa-miR-3129-5p	CLIP-seq
MIRT1018165	hsa-miR-323-3p	CLIP-seq
MIRT1018166	hsa-miR-3659	CLIP-seq
MIRT1018167	hsa-miR-3686	CLIP-seq
MIRT1018168	hsa-miR-382	CLIP-seq
MIRT1018169	hsa-miR-4252	CLIP-seq
MIRT1018170	hsa-miR-4311	CLIP-seq
MIRT1018171	hsa-miR-450b-5p	CLIP-seq
MIRT1018172	hsa-miR-4652-3p	CLIP-seq
MIRT1018173	hsa-miR-4658	CLIP-seq
MIRT1018174	hsa-miR-4715-3p	CLIP-seq
MIRT1018175	hsa-miR-4776-3p	CLIP-seq
MIRT1018176	hsa-miR-488	CLIP-seq
MIRT1018177	hsa-miR-507	CLIP-seq
MIRT1018178	hsa-miR-513a-3p	CLIP-seq
MIRT1018179	hsa-miR-524-3p	CLIP-seq
MIRT1018180	hsa-miR-525-3p	CLIP-seq
MIRT1018181	hsa-miR-557	CLIP-seq
MIRT1018182	hsa-miR-574-5p	CLIP-seq
MIRT1018183	hsa-miR-616	CLIP-seq
MIRT1018165	hsa-miR-323-3p	CLIP-seq
MIRT1018175	hsa-miR-4776-3p	CLIP-seq
MIRT2001568	hsa-miR-513a-5p	CLIP-seq
MIRT2234586	hsa-miR-1264	CLIP-seq
MIRT1018158	hsa-miR-129-5p	CLIP-seq
MIRT1018161	hsa-miR-199a-3p	CLIP-seq
MIRT1018162	hsa-miR-199b-3p	CLIP-seq
MIRT2234587	hsa-miR-224	CLIP-seq
MIRT1018163	hsa-miR-3064-3p	CLIP-seq
MIRT1018164	hsa-miR-3129-5p	CLIP-seq
MIRT1018165	hsa-miR-323-3p	CLIP-seq
MIRT2234588	hsa-miR-342-3p	CLIP-seq
MIRT2234589	hsa-miR-3618	CLIP-seq
MIRT1018167	hsa-miR-3686	CLIP-seq
MIRT2234590	hsa-miR-3691-5p	CLIP-seq
MIRT1018168	hsa-miR-382	CLIP-seq
MIRT1018169	hsa-miR-4252	CLIP-seq
MIRT2234591	hsa-miR-4289	CLIP-seq
MIRT1018170	hsa-miR-4311	CLIP-seq
MIRT1018172	hsa-miR-4652-3p	CLIP-seq
MIRT2234592	hsa-miR-4659a-5p	CLIP-seq
MIRT2234593	hsa-miR-4659b-5p	CLIP-seq
MIRT1018174	hsa-miR-4715-3p	CLIP-seq
MIRT2234594	hsa-miR-4764-5p	CLIP-seq
MIRT1018175	hsa-miR-4776-3p	CLIP-seq
MIRT2001568	hsa-miR-513a-5p	CLIP-seq
MIRT1018179	hsa-miR-524-3p	CLIP-seq
MIRT1018180	hsa-miR-525-3p	CLIP-seq
MIRT2234595	hsa-miR-548aa	CLIP-seq
MIRT1018183	hsa-miR-616	CLIP-seq
MIRT2234596	hsa-miR-934	CLIP-seq

Show/Hide all(13)

GO ID	Ontology	Definition	Evidence
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0007283	Process	Spermatogenesis	IEA
GO:0008285	Process	Negative regulation of cell population proliferation	IEA
GO:0010629	Process	Negative regulation of gene expression	IEA
GO:0030154	Process	Cell differentiation	IEA
GO:0030154	Process	Cell differentiation	IEA
GO:0031410	Component	Cytoplasmic vesicle	IEA
GO:0060711	Process	Labyrinthine layer development	IEA
GO:0060716	Process	Labyrinthine layer blood vessel development	IEA
GO:1904893	Process	Negative regulation of receptor signaling pathway via STAT	IEA

MIM	HGNC	e!Ensembl
612275	19357	ENSG00000278311

Protein

UniProt ID

Q9H3C7

Protein name

Gametogenetin-binding protein 2 (Laryngeal carcinoma-related protein 1) (Protein ZNF403)

Protein function

May be involved in spermatogenesis.

PDB

8BFJ

Family and domains

Tissue specificity

TISSUE SPECIFICITY: Expressed in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas. Expressed more abundantly in heart, pancreas and skeletal muscle. {ECO:0000269|PubMed:15145523}.

Sequence

MARLVAVCRDGEEEFPFERRQIPLYIDDTLTMVMEFPDNVLNLDGHQNNGAQLKQFIQRH
GMLKQQDLSIAMVVTSREVLSALSQLVPCVGCRRSVERLFSQLVESGNPALEPLTVGPKG
VLSVTRSCMTDAKKLYTLFYVHGSKLNDMIDAIPKSKKNKRCQLHSLDTHKPKPLGGCWM
DVWELMSQECRDEVVLIDSSCLLETLETYLRKHRFCTDCKNKVLRAYNILIGELDCSKEK
GYCAALYEGLRCCPHERHIHVCCETDFIAHLLGRAEPEFAGGRRERHAKTIDIAQEEVLT
CLGIHLYERLHRIWQKLRAEEQTWQMLFYLGVDALRKSFEMTVEKVQGISRLEQLCEEFS
EEERVRELKQEKKRQKRKNRRKNKCVCDIPTPLQTADEKEVSQEKETDFIENSSCKACGS
TEDGNTCVEVIVTNENTSCTCPSSGNLLGSPKIKKGLSPHCNGSDCGYSSSMEGSETGSR
EGSDVACTEGICNHDEHGDDSCVHHCEDKEDDGDSCVECWANSEENDTKGKNKKKKKKSK
ILKCDEHIQKLGSCITDPGNRETSGNTMHTVFHRDKTKDTHPESCCSSEKGGQPLPWFEH
RKNVPQFAEPTETLFGPDSGKGAKSLVELLDESECTSDEEIFISQDEIQSFMANNQSFYS
NREQYRQHLKEKFNKYCRLNDHKRPICSGWLTTAGAN

Sequence length

697

Interactions

View interactions

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Dyslexia	Dyslexia	N/A	N/A	GWAS
Eczema	Eczema	N/A	N/A	GWAS

Show/Hide Text Mining Associations (8)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Amyotrophic Lateral Sclerosis	Associate	28639078, 33541344
Diabetes Mellitus	Associate	36109160
Glioma	Inhibit	28244851
Multiple Sclerosis	Associate	37300932
Myoepithelioma	Associate	36577525
Neoplasms	Inhibit	28244851
Neoplasms	Associate	36577525
Obesity	Associate	37300932

GGNBP2 (gametogenetin binding protein 2)