FBXO31 (F-box protein 31)

Gene

• Entrez ID: 79791
• Gene name: F-box protein 31
• Gene symbol: FBXO31
• Synonyms (NCBI Gene): FBX14, FBXO14, Fbx31, MRT45, pp2386
• Chromosome: 16
• Chromosome location: 16q24.2
• Summary: This gene is a member of the F-box family. Members are classified into three classes according to the substrate interaction domain, FBW for WD40 repeats, FBL for leucing-rich repeats, and FBXO for other domains. This protein, classified into the last cate

SNPs

SNP ID	Visualize variation	Clinical significance	Consequence
rs587777703	CAGGCA>T	Pathogenic	Frameshift variant, coding sequence variant

miRNA

miRTarBase ID	miRNA	Experiments	Reference
MIRT004529	hsa-miR-17-5p	Luciferase reporter assay	19734348
MIRT026239	hsa-miR-192-5p	Microarray	19074876
MIRT044521	hsa-miR-320a	CLASH	23622248
MIRT040924	hsa-miR-18a-3p	CLASH	23622248
MIRT040530	hsa-miR-92b-3p	CLASH	23622248
MIRT004529	hsa-miR-17-5p	Luciferase reporter assay, qRT-PCR, Western blot	25115392
MIRT004529	hsa-miR-17-5p	Luciferase reporter assay, qRT-PCR, Western blot	25115392
MIRT438351	hsa-miR-20a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25115392
MIRT438351	hsa-miR-20a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25115392
MIRT004529	hsa-miR-17-5p	Luciferase reporter assay, qRT-PCR, Western blot	25115392
MIRT004529	hsa-miR-17-5p	Luciferase reporter assay, qRT-PCR, Western blot	25115392
MIRT438351	hsa-miR-20a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25115392
MIRT438351	hsa-miR-20a-5p	Luciferase reporter assay, qRT-PCR, Western blot	25115392
MIRT714405	hsa-miR-3667-5p	HITS-CLIP	19536157
MIRT714404	hsa-miR-3529-3p	HITS-CLIP	19536157
MIRT714403	hsa-miR-10a-5p	HITS-CLIP	19536157
MIRT714402	hsa-miR-10b-5p	HITS-CLIP	19536157
MIRT714401	hsa-miR-451b	HITS-CLIP	19536157
MIRT714400	hsa-miR-3613-3p	HITS-CLIP	19536157
MIRT714399	hsa-miR-3065-5p	HITS-CLIP	19536157
MIRT714398	hsa-miR-339-5p	HITS-CLIP	19536157
MIRT714397	hsa-miR-4421	HITS-CLIP	19536157
MIRT714396	hsa-miR-5699-3p	HITS-CLIP	19536157
MIRT714395	hsa-miR-371b-5p	HITS-CLIP	19536157
MIRT714394	hsa-miR-373-5p	HITS-CLIP	19536157
MIRT714393	hsa-miR-616-5p	HITS-CLIP	19536157
MIRT714392	hsa-miR-371a-5p	HITS-CLIP	19536157
MIRT714391	hsa-miR-372-5p	HITS-CLIP	19536157
MIRT714390	hsa-miR-4725-5p	HITS-CLIP	19536157
MIRT714389	hsa-miR-4696	HITS-CLIP	19536157
MIRT647968	hsa-miR-6768-3p	HITS-CLIP	23824327
MIRT647967	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT647966	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT647965	hsa-miR-8073	HITS-CLIP	23824327
MIRT647963	hsa-miR-4287	HITS-CLIP	23824327
MIRT647964	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT647962	hsa-miR-3064-5p	HITS-CLIP	23824327
MIRT647961	hsa-miR-6504-5p	HITS-CLIP	23824327
MIRT647960	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT647959	hsa-miR-3926	HITS-CLIP	23824327
MIRT647958	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT647957	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT647956	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT647955	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT647954	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT647953	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT440656	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT438351	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT440656	hsa-miR-106b-5p	HITS-CLIP	22473208
MIRT004529	hsa-miR-17-5p	HITS-CLIP	22473208
MIRT727670	hsa-miR-20b-5p	HITS-CLIP	22473208
MIRT727669	hsa-miR-93-5p	HITS-CLIP	22473208
MIRT727668	hsa-miR-519d-3p	HITS-CLIP	22473208
MIRT438351	hsa-miR-20a-5p	HITS-CLIP	22473208
MIRT714405	hsa-miR-3667-5p	HITS-CLIP	19536157
MIRT714404	hsa-miR-3529-3p	HITS-CLIP	19536157
MIRT714403	hsa-miR-10a-5p	HITS-CLIP	19536157
MIRT714402	hsa-miR-10b-5p	HITS-CLIP	19536157
MIRT714401	hsa-miR-451b	HITS-CLIP	19536157
MIRT714400	hsa-miR-3613-3p	HITS-CLIP	19536157
MIRT714399	hsa-miR-3065-5p	HITS-CLIP	19536157
MIRT714398	hsa-miR-339-5p	HITS-CLIP	19536157
MIRT714397	hsa-miR-4421	HITS-CLIP	19536157
MIRT714396	hsa-miR-5699-3p	HITS-CLIP	19536157
MIRT714395	hsa-miR-371b-5p	HITS-CLIP	19536157
MIRT714394	hsa-miR-373-5p	HITS-CLIP	19536157
MIRT714393	hsa-miR-616-5p	HITS-CLIP	19536157
MIRT714392	hsa-miR-371a-5p	HITS-CLIP	19536157
MIRT714391	hsa-miR-372-5p	HITS-CLIP	19536157
MIRT714390	hsa-miR-4725-5p	HITS-CLIP	19536157
MIRT714389	hsa-miR-4696	HITS-CLIP	19536157
MIRT647968	hsa-miR-6768-3p	HITS-CLIP	23824327
MIRT647967	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT647966	hsa-miR-221-5p	HITS-CLIP	23824327
MIRT647965	hsa-miR-8073	HITS-CLIP	23824327
MIRT647963	hsa-miR-4287	HITS-CLIP	23824327
MIRT647964	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT647962	hsa-miR-3064-5p	HITS-CLIP	23824327
MIRT647961	hsa-miR-6504-5p	HITS-CLIP	23824327
MIRT647960	hsa-miR-3124-3p	HITS-CLIP	23824327
MIRT647959	hsa-miR-3926	HITS-CLIP	23824327
MIRT647958	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT647957	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT647956	hsa-miR-1343-3p	HITS-CLIP	23824327
MIRT647955	hsa-miR-6783-3p	HITS-CLIP	23824327
MIRT647954	hsa-miR-3074-5p	HITS-CLIP	23824327
MIRT647953	hsa-miR-7152-5p	HITS-CLIP	23824327
MIRT991848	hsa-miR-106a	CLIP-seq
MIRT991849	hsa-miR-106b	CLIP-seq
MIRT991850	hsa-miR-1207-5p	CLIP-seq
MIRT991851	hsa-miR-1225-3p	CLIP-seq
MIRT991852	hsa-miR-1231	CLIP-seq
MIRT991853	hsa-miR-124	CLIP-seq
MIRT991854	hsa-miR-125a-3p	CLIP-seq
MIRT991855	hsa-miR-1269	CLIP-seq
MIRT991856	hsa-miR-1269b	CLIP-seq
MIRT991857	hsa-miR-1288	CLIP-seq
MIRT991858	hsa-miR-1299	CLIP-seq
MIRT991859	hsa-miR-1321	CLIP-seq
MIRT991860	hsa-miR-142-5p	CLIP-seq
MIRT991861	hsa-miR-146b-3p	CLIP-seq
MIRT991862	hsa-miR-151-5p	CLIP-seq
MIRT991863	hsa-miR-151b	CLIP-seq
MIRT991864	hsa-miR-1587	CLIP-seq
MIRT991865	hsa-miR-17	CLIP-seq
MIRT991866	hsa-miR-1909	CLIP-seq
MIRT991867	hsa-miR-20a	CLIP-seq
MIRT991868	hsa-miR-20b	CLIP-seq
MIRT991869	hsa-miR-210	CLIP-seq
MIRT991870	hsa-miR-27a	CLIP-seq
MIRT991871	hsa-miR-27b	CLIP-seq
MIRT991872	hsa-miR-296-5p	CLIP-seq
MIRT991873	hsa-miR-302a	CLIP-seq
MIRT991874	hsa-miR-302b	CLIP-seq
MIRT991875	hsa-miR-302c	CLIP-seq
MIRT991876	hsa-miR-302d	CLIP-seq
MIRT991877	hsa-miR-302e	CLIP-seq
MIRT991878	hsa-miR-3120-5p	CLIP-seq
MIRT991879	hsa-miR-3121-5p	CLIP-seq
MIRT991880	hsa-miR-3130-5p	CLIP-seq
MIRT991881	hsa-miR-3131	CLIP-seq
MIRT991882	hsa-miR-3167	CLIP-seq
MIRT991883	hsa-miR-342-3p	CLIP-seq
MIRT991884	hsa-miR-3609	CLIP-seq
MIRT991885	hsa-miR-3616-3p	CLIP-seq
MIRT991886	hsa-miR-3622b-5p	CLIP-seq
MIRT991887	hsa-miR-3652	CLIP-seq
MIRT991888	hsa-miR-3663-5p	CLIP-seq
MIRT991889	hsa-miR-3665	CLIP-seq
MIRT991890	hsa-miR-372	CLIP-seq
MIRT991891	hsa-miR-373	CLIP-seq
MIRT991892	hsa-miR-377	CLIP-seq
MIRT991893	hsa-miR-378	CLIP-seq
MIRT991894	hsa-miR-378b	CLIP-seq
MIRT991895	hsa-miR-378c	CLIP-seq
MIRT991896	hsa-miR-378d	CLIP-seq
MIRT991897	hsa-miR-378e	CLIP-seq
MIRT991898	hsa-miR-378f	CLIP-seq
MIRT991899	hsa-miR-378g	CLIP-seq
MIRT991900	hsa-miR-378h	CLIP-seq
MIRT991901	hsa-miR-378i	CLIP-seq
MIRT991902	hsa-miR-3910	CLIP-seq
MIRT991903	hsa-miR-3914	CLIP-seq
MIRT991904	hsa-miR-3922-5p	CLIP-seq
MIRT991905	hsa-miR-3934	CLIP-seq
MIRT991906	hsa-miR-422a	CLIP-seq
MIRT991907	hsa-miR-4270	CLIP-seq
MIRT991908	hsa-miR-4323	CLIP-seq
MIRT991909	hsa-miR-4430	CLIP-seq
MIRT991910	hsa-miR-4436b-3p	CLIP-seq
MIRT991911	hsa-miR-4441	CLIP-seq
MIRT991912	hsa-miR-4476	CLIP-seq
MIRT991913	hsa-miR-4482	CLIP-seq
MIRT991914	hsa-miR-4492	CLIP-seq
MIRT991915	hsa-miR-4494	CLIP-seq
MIRT991916	hsa-miR-4498	CLIP-seq
MIRT991917	hsa-miR-4504	CLIP-seq
MIRT991918	hsa-miR-4505	CLIP-seq
MIRT991919	hsa-miR-4515	CLIP-seq
MIRT991920	hsa-miR-4639-3p	CLIP-seq
MIRT991921	hsa-miR-4645-5p	CLIP-seq
MIRT991922	hsa-miR-4651	CLIP-seq
MIRT991923	hsa-miR-4656	CLIP-seq
MIRT991924	hsa-miR-4673	CLIP-seq
MIRT991925	hsa-miR-4675	CLIP-seq
MIRT991926	hsa-miR-4684-5p	CLIP-seq
MIRT991927	hsa-miR-4691-5p	CLIP-seq
MIRT991928	hsa-miR-4704-3p	CLIP-seq
MIRT991929	hsa-miR-4717-5p	CLIP-seq
MIRT991930	hsa-miR-4731-5p	CLIP-seq
MIRT991931	hsa-miR-4736	CLIP-seq
MIRT991932	hsa-miR-4739	CLIP-seq
MIRT991933	hsa-miR-4740-5p	CLIP-seq
MIRT991934	hsa-miR-4741	CLIP-seq
MIRT991935	hsa-miR-4743	CLIP-seq
MIRT991936	hsa-miR-4753-5p	CLIP-seq
MIRT991937	hsa-miR-4756-5p	CLIP-seq
MIRT991938	hsa-miR-4763-3p	CLIP-seq
MIRT991939	hsa-miR-4776-3p	CLIP-seq
MIRT991940	hsa-miR-4796-3p	CLIP-seq
MIRT991941	hsa-miR-486-3p	CLIP-seq
MIRT991942	hsa-miR-495	CLIP-seq
MIRT991943	hsa-miR-506	CLIP-seq
MIRT991944	hsa-miR-512-3p	CLIP-seq
MIRT991945	hsa-miR-513a-5p	CLIP-seq
MIRT991946	hsa-miR-519a	CLIP-seq
MIRT991947	hsa-miR-519b-3p	CLIP-seq
MIRT991948	hsa-miR-519c-3p	CLIP-seq
MIRT991949	hsa-miR-519d	CLIP-seq
MIRT991950	hsa-miR-520a-3p	CLIP-seq
MIRT991951	hsa-miR-520b	CLIP-seq
MIRT991952	hsa-miR-520c-3p	CLIP-seq
MIRT991953	hsa-miR-520d-3p	CLIP-seq
MIRT991954	hsa-miR-520e	CLIP-seq
MIRT991955	hsa-miR-520g	CLIP-seq
MIRT991956	hsa-miR-520h	CLIP-seq
MIRT991957	hsa-miR-548ah	CLIP-seq
MIRT991958	hsa-miR-551a	CLIP-seq
MIRT991959	hsa-miR-551b	CLIP-seq
MIRT991960	hsa-miR-608	CLIP-seq
MIRT991961	hsa-miR-611	CLIP-seq
MIRT991962	hsa-miR-637	CLIP-seq
MIRT991963	hsa-miR-651	CLIP-seq
MIRT991964	hsa-miR-657	CLIP-seq
MIRT991965	hsa-miR-759	CLIP-seq
MIRT991966	hsa-miR-762	CLIP-seq
MIRT991967	hsa-miR-764	CLIP-seq
MIRT991968	hsa-miR-875-3p	CLIP-seq
MIRT991969	hsa-miR-876-5p	CLIP-seq
MIRT991970	hsa-miR-93	CLIP-seq
MIRT1994166	hsa-miR-105	CLIP-seq
MIRT991848	hsa-miR-106a	CLIP-seq
MIRT991849	hsa-miR-106b	CLIP-seq
MIRT991850	hsa-miR-1207-5p	CLIP-seq
MIRT1994167	hsa-miR-1226	CLIP-seq
MIRT991852	hsa-miR-1231	CLIP-seq
MIRT1994168	hsa-miR-1238	CLIP-seq
MIRT991855	hsa-miR-1269	CLIP-seq
MIRT991856	hsa-miR-1269b	CLIP-seq
MIRT1994169	hsa-miR-1285	CLIP-seq
MIRT1994170	hsa-miR-1286	CLIP-seq
MIRT991857	hsa-miR-1288	CLIP-seq
MIRT991858	hsa-miR-1299	CLIP-seq
MIRT1994171	hsa-miR-140-3p	CLIP-seq
MIRT991860	hsa-miR-142-5p	CLIP-seq
MIRT991861	hsa-miR-146b-3p	CLIP-seq
MIRT991862	hsa-miR-151-5p	CLIP-seq
MIRT991863	hsa-miR-151b	CLIP-seq
MIRT1994172	hsa-miR-155	CLIP-seq
MIRT991864	hsa-miR-1587	CLIP-seq
MIRT991865	hsa-miR-17	CLIP-seq
MIRT1994173	hsa-miR-183	CLIP-seq
MIRT1994174	hsa-miR-198	CLIP-seq
MIRT991867	hsa-miR-20a	CLIP-seq
MIRT991868	hsa-miR-20b	CLIP-seq
MIRT991869	hsa-miR-210	CLIP-seq
MIRT1994175	hsa-miR-2110	CLIP-seq
MIRT1994176	hsa-miR-214	CLIP-seq
MIRT1994177	hsa-miR-2467-5p	CLIP-seq
MIRT1994178	hsa-miR-2681	CLIP-seq
MIRT991872	hsa-miR-296-5p	CLIP-seq
MIRT1994179	hsa-miR-29a	CLIP-seq
MIRT1994180	hsa-miR-29b	CLIP-seq
MIRT1994181	hsa-miR-29c	CLIP-seq
MIRT991873	hsa-miR-302a	CLIP-seq
MIRT991874	hsa-miR-302b	CLIP-seq
MIRT991875	hsa-miR-302c	CLIP-seq
MIRT991876	hsa-miR-302d	CLIP-seq
MIRT991877	hsa-miR-302e	CLIP-seq
MIRT991878	hsa-miR-3120-5p	CLIP-seq
MIRT991881	hsa-miR-3131	CLIP-seq
MIRT991882	hsa-miR-3167	CLIP-seq
MIRT1994182	hsa-miR-3187-5p	CLIP-seq
MIRT1994183	hsa-miR-3188	CLIP-seq
MIRT1994184	hsa-miR-320b	CLIP-seq
MIRT1994185	hsa-miR-320c	CLIP-seq
MIRT1994186	hsa-miR-320d	CLIP-seq
MIRT1994187	hsa-miR-320e	CLIP-seq
MIRT991884	hsa-miR-3609	CLIP-seq
MIRT991885	hsa-miR-3616-3p	CLIP-seq
MIRT1994188	hsa-miR-3619-5p	CLIP-seq
MIRT1994189	hsa-miR-3622a-3p	CLIP-seq
MIRT1994190	hsa-miR-3622b-3p	CLIP-seq
MIRT991887	hsa-miR-3652	CLIP-seq
MIRT1994191	hsa-miR-3663-3p	CLIP-seq
MIRT991888	hsa-miR-3663-5p	CLIP-seq
MIRT991889	hsa-miR-3665	CLIP-seq
MIRT991890	hsa-miR-372	CLIP-seq
MIRT991891	hsa-miR-373	CLIP-seq
MIRT991893	hsa-miR-378	CLIP-seq
MIRT991894	hsa-miR-378b	CLIP-seq
MIRT991895	hsa-miR-378c	CLIP-seq
MIRT991896	hsa-miR-378d	CLIP-seq
MIRT991897	hsa-miR-378e	CLIP-seq
MIRT991898	hsa-miR-378f	CLIP-seq
MIRT991900	hsa-miR-378h	CLIP-seq
MIRT991901	hsa-miR-378i	CLIP-seq
MIRT1994192	hsa-miR-383	CLIP-seq
MIRT991905	hsa-miR-3934	CLIP-seq
MIRT1994193	hsa-miR-3936	CLIP-seq
MIRT1994194	hsa-miR-3938	CLIP-seq
MIRT1994195	hsa-miR-3975	CLIP-seq
MIRT991906	hsa-miR-422a	CLIP-seq
MIRT991907	hsa-miR-4270	CLIP-seq
MIRT1994196	hsa-miR-4271	CLIP-seq
MIRT1994197	hsa-miR-4429	CLIP-seq
MIRT991909	hsa-miR-4430	CLIP-seq
MIRT991910	hsa-miR-4436b-3p	CLIP-seq
MIRT991911	hsa-miR-4441	CLIP-seq
MIRT1994198	hsa-miR-4457	CLIP-seq
MIRT991914	hsa-miR-4492	CLIP-seq
MIRT991916	hsa-miR-4498	CLIP-seq
MIRT991917	hsa-miR-4504	CLIP-seq
MIRT991918	hsa-miR-4505	CLIP-seq
MIRT991919	hsa-miR-4515	CLIP-seq
MIRT1994199	hsa-miR-4530	CLIP-seq
MIRT991920	hsa-miR-4639-3p	CLIP-seq
MIRT1994200	hsa-miR-4649-3p	CLIP-seq
MIRT991922	hsa-miR-4651	CLIP-seq
MIRT991923	hsa-miR-4656	CLIP-seq
MIRT991925	hsa-miR-4675	CLIP-seq
MIRT991926	hsa-miR-4684-5p	CLIP-seq
MIRT1994201	hsa-miR-4685-5p	CLIP-seq
MIRT1994202	hsa-miR-4690-3p	CLIP-seq
MIRT1994203	hsa-miR-4725-3p	CLIP-seq
MIRT1994204	hsa-miR-4731-3p	CLIP-seq
MIRT991930	hsa-miR-4731-5p	CLIP-seq
MIRT1994205	hsa-miR-4733-3p	CLIP-seq
MIRT1994206	hsa-miR-4740-3p	CLIP-seq
MIRT991933	hsa-miR-4740-5p	CLIP-seq
MIRT991934	hsa-miR-4741	CLIP-seq
MIRT991935	hsa-miR-4743	CLIP-seq
MIRT991938	hsa-miR-4763-3p	CLIP-seq
MIRT1994207	hsa-miR-4778-3p	CLIP-seq
MIRT991940	hsa-miR-4796-3p	CLIP-seq
MIRT1994208	hsa-miR-4801	CLIP-seq
MIRT1994209	hsa-miR-483-3p	CLIP-seq
MIRT1994210	hsa-miR-485-5p	CLIP-seq
MIRT1994211	hsa-miR-491-5p	CLIP-seq
MIRT991942	hsa-miR-495	CLIP-seq
MIRT991944	hsa-miR-512-3p	CLIP-seq
MIRT991945	hsa-miR-513a-5p	CLIP-seq
MIRT1994212	hsa-miR-518a-5p	CLIP-seq
MIRT991949	hsa-miR-519d	CLIP-seq
MIRT991950	hsa-miR-520a-3p	CLIP-seq
MIRT991951	hsa-miR-520b	CLIP-seq
MIRT991952	hsa-miR-520c-3p	CLIP-seq
MIRT991953	hsa-miR-520d-3p	CLIP-seq
MIRT991954	hsa-miR-520e	CLIP-seq
MIRT1994213	hsa-miR-527	CLIP-seq
MIRT1994214	hsa-miR-539	CLIP-seq
MIRT991957	hsa-miR-548ah	CLIP-seq
MIRT1994215	hsa-miR-552	CLIP-seq
MIRT991960	hsa-miR-608	CLIP-seq
MIRT991961	hsa-miR-611	CLIP-seq
MIRT1994216	hsa-miR-612	CLIP-seq
MIRT1994217	hsa-miR-634	CLIP-seq
MIRT991962	hsa-miR-637	CLIP-seq
MIRT991964	hsa-miR-657	CLIP-seq
MIRT1994218	hsa-miR-761	CLIP-seq
MIRT991966	hsa-miR-762	CLIP-seq
MIRT991968	hsa-miR-875-3p	CLIP-seq
MIRT991969	hsa-miR-876-5p	CLIP-seq
MIRT991970	hsa-miR-93	CLIP-seq
MIRT991848	hsa-miR-106a	CLIP-seq
MIRT991849	hsa-miR-106b	CLIP-seq
MIRT991850	hsa-miR-1207-5p	CLIP-seq
MIRT2228135	hsa-miR-1229	CLIP-seq
MIRT991855	hsa-miR-1269	CLIP-seq
MIRT991856	hsa-miR-1269b	CLIP-seq
MIRT2228136	hsa-miR-1271	CLIP-seq
MIRT991857	hsa-miR-1288	CLIP-seq
MIRT1994171	hsa-miR-140-3p	CLIP-seq
MIRT991860	hsa-miR-142-5p	CLIP-seq
MIRT2228137	hsa-miR-147	CLIP-seq
MIRT1994172	hsa-miR-155	CLIP-seq
MIRT991865	hsa-miR-17	CLIP-seq
MIRT2228138	hsa-miR-182	CLIP-seq
MIRT2228139	hsa-miR-1910	CLIP-seq
MIRT991867	hsa-miR-20a	CLIP-seq
MIRT991868	hsa-miR-20b	CLIP-seq
MIRT1994176	hsa-miR-214	CLIP-seq
MIRT991870	hsa-miR-27a	CLIP-seq
MIRT991871	hsa-miR-27b	CLIP-seq
MIRT991873	hsa-miR-302a	CLIP-seq
MIRT991874	hsa-miR-302b	CLIP-seq
MIRT991875	hsa-miR-302c	CLIP-seq
MIRT991876	hsa-miR-302d	CLIP-seq
MIRT991877	hsa-miR-302e	CLIP-seq
MIRT2228140	hsa-miR-31	CLIP-seq
MIRT2228141	hsa-miR-3135b	CLIP-seq
MIRT2228142	hsa-miR-3138	CLIP-seq
MIRT991882	hsa-miR-3167	CLIP-seq
MIRT2228143	hsa-miR-3186-3p	CLIP-seq
MIRT991884	hsa-miR-3609	CLIP-seq
MIRT2228144	hsa-miR-3612	CLIP-seq
MIRT991885	hsa-miR-3616-3p	CLIP-seq
MIRT2228145	hsa-miR-3619-3p	CLIP-seq
MIRT1994188	hsa-miR-3619-5p	CLIP-seq
MIRT991887	hsa-miR-3652	CLIP-seq
MIRT991889	hsa-miR-3665	CLIP-seq
MIRT2228146	hsa-miR-3680	CLIP-seq
MIRT991890	hsa-miR-372	CLIP-seq
MIRT991891	hsa-miR-373	CLIP-seq
MIRT991893	hsa-miR-378	CLIP-seq
MIRT991894	hsa-miR-378b	CLIP-seq
MIRT991895	hsa-miR-378c	CLIP-seq
MIRT991896	hsa-miR-378d	CLIP-seq
MIRT991897	hsa-miR-378e	CLIP-seq
MIRT991898	hsa-miR-378f	CLIP-seq
MIRT991900	hsa-miR-378h	CLIP-seq
MIRT991901	hsa-miR-378i	CLIP-seq
MIRT2228147	hsa-miR-3911	CLIP-seq
MIRT2228148	hsa-miR-3919	CLIP-seq
MIRT991906	hsa-miR-422a	CLIP-seq
MIRT991907	hsa-miR-4270	CLIP-seq
MIRT991909	hsa-miR-4430	CLIP-seq
MIRT991910	hsa-miR-4436b-3p	CLIP-seq
MIRT991911	hsa-miR-4441	CLIP-seq
MIRT2228149	hsa-miR-4443	CLIP-seq
MIRT991917	hsa-miR-4504	CLIP-seq
MIRT991918	hsa-miR-4505	CLIP-seq
MIRT991919	hsa-miR-4515	CLIP-seq
MIRT2228150	hsa-miR-4519	CLIP-seq
MIRT1994199	hsa-miR-4530	CLIP-seq
MIRT2228151	hsa-miR-455-3p	CLIP-seq
MIRT991922	hsa-miR-4651	CLIP-seq
MIRT1994202	hsa-miR-4690-3p	CLIP-seq
MIRT2228152	hsa-miR-4711-5p	CLIP-seq
MIRT991930	hsa-miR-4731-5p	CLIP-seq
MIRT991933	hsa-miR-4740-5p	CLIP-seq
MIRT991935	hsa-miR-4743	CLIP-seq
MIRT2228153	hsa-miR-4746-5p	CLIP-seq
MIRT2228154	hsa-miR-4747-5p	CLIP-seq
MIRT2228155	hsa-miR-4756-3p	CLIP-seq
MIRT991938	hsa-miR-4763-3p	CLIP-seq
MIRT2228156	hsa-miR-4776-5p	CLIP-seq
MIRT991940	hsa-miR-4796-3p	CLIP-seq
MIRT2228157	hsa-miR-4800-5p	CLIP-seq
MIRT991944	hsa-miR-512-3p	CLIP-seq
MIRT991945	hsa-miR-513a-5p	CLIP-seq
MIRT991946	hsa-miR-519a	CLIP-seq
MIRT991947	hsa-miR-519b-3p	CLIP-seq
MIRT991948	hsa-miR-519c-3p	CLIP-seq
MIRT991949	hsa-miR-519d	CLIP-seq
MIRT991950	hsa-miR-520a-3p	CLIP-seq
MIRT991951	hsa-miR-520b	CLIP-seq
MIRT991952	hsa-miR-520c-3p	CLIP-seq
MIRT991953	hsa-miR-520d-3p	CLIP-seq
MIRT991954	hsa-miR-520e	CLIP-seq
MIRT991955	hsa-miR-520g	CLIP-seq
MIRT991956	hsa-miR-520h	CLIP-seq
MIRT991957	hsa-miR-548ah	CLIP-seq
MIRT2228158	hsa-miR-579	CLIP-seq
MIRT991960	hsa-miR-608	CLIP-seq
MIRT991962	hsa-miR-637	CLIP-seq
MIRT2228159	hsa-miR-644	CLIP-seq
MIRT2228160	hsa-miR-650	CLIP-seq
MIRT2228161	hsa-miR-662	CLIP-seq
MIRT2228162	hsa-miR-668	CLIP-seq
MIRT991965	hsa-miR-759	CLIP-seq
MIRT1994218	hsa-miR-761	CLIP-seq
MIRT991969	hsa-miR-876-5p	CLIP-seq
MIRT991970	hsa-miR-93	CLIP-seq
MIRT2228163	hsa-miR-96	CLIP-seq
MIRT991851	hsa-miR-1225-3p	CLIP-seq
MIRT991864	hsa-miR-1587	CLIP-seq
MIRT991889	hsa-miR-3665	CLIP-seq
MIRT991899	hsa-miR-378g	CLIP-seq
MIRT991907	hsa-miR-4270	CLIP-seq
MIRT991908	hsa-miR-4323	CLIP-seq
MIRT991911	hsa-miR-4441	CLIP-seq
MIRT991914	hsa-miR-4492	CLIP-seq
MIRT991916	hsa-miR-4498	CLIP-seq
MIRT991918	hsa-miR-4505	CLIP-seq
MIRT991923	hsa-miR-4656	CLIP-seq
MIRT991925	hsa-miR-4675	CLIP-seq
MIRT991931	hsa-miR-4736	CLIP-seq
MIRT991934	hsa-miR-4741	CLIP-seq
MIRT991941	hsa-miR-486-3p	CLIP-seq
MIRT991966	hsa-miR-762	CLIP-seq
MIRT991967	hsa-miR-764	CLIP-seq
MIRT1994166	hsa-miR-105	CLIP-seq
MIRT1994167	hsa-miR-1226	CLIP-seq
MIRT991854	hsa-miR-125a-3p	CLIP-seq
MIRT1994169	hsa-miR-1285	CLIP-seq
MIRT1994170	hsa-miR-1286	CLIP-seq
MIRT991864	hsa-miR-1587	CLIP-seq
MIRT1994174	hsa-miR-198	CLIP-seq
MIRT2531693	hsa-miR-2116	CLIP-seq
MIRT1994176	hsa-miR-214	CLIP-seq
MIRT1994177	hsa-miR-2467-5p	CLIP-seq
MIRT1994179	hsa-miR-29a	CLIP-seq
MIRT1994180	hsa-miR-29b	CLIP-seq
MIRT1994181	hsa-miR-29c	CLIP-seq
MIRT991880	hsa-miR-3130-5p	CLIP-seq
MIRT2228141	hsa-miR-3135b	CLIP-seq
MIRT2531694	hsa-miR-3144-5p	CLIP-seq
MIRT2531695	hsa-miR-3184	CLIP-seq
MIRT1994182	hsa-miR-3187-5p	CLIP-seq
MIRT1994183	hsa-miR-3188	CLIP-seq
MIRT2531696	hsa-miR-3191	CLIP-seq
MIRT2531697	hsa-miR-3192	CLIP-seq
MIRT1994184	hsa-miR-320b	CLIP-seq
MIRT1994185	hsa-miR-320c	CLIP-seq
MIRT1994186	hsa-miR-320d	CLIP-seq
MIRT1994187	hsa-miR-320e	CLIP-seq
MIRT2531698	hsa-miR-326	CLIP-seq
MIRT2531699	hsa-miR-330-5p	CLIP-seq
MIRT2531700	hsa-miR-345	CLIP-seq
MIRT2531701	hsa-miR-34c-3p	CLIP-seq
MIRT1994188	hsa-miR-3619-5p	CLIP-seq
MIRT1994191	hsa-miR-3663-3p	CLIP-seq
MIRT991889	hsa-miR-3665	CLIP-seq
MIRT991892	hsa-miR-377	CLIP-seq
MIRT991899	hsa-miR-378g	CLIP-seq
MIRT991905	hsa-miR-3934	CLIP-seq
MIRT1994194	hsa-miR-3938	CLIP-seq
MIRT2531702	hsa-miR-3973	CLIP-seq
MIRT1994195	hsa-miR-3975	CLIP-seq
MIRT2531703	hsa-miR-423-5p	CLIP-seq
MIRT2531704	hsa-miR-4314	CLIP-seq
MIRT2531705	hsa-miR-432	CLIP-seq
MIRT2531706	hsa-miR-4428	CLIP-seq
MIRT1994197	hsa-miR-4429	CLIP-seq
MIRT2531707	hsa-miR-4433	CLIP-seq
MIRT1994198	hsa-miR-4457	CLIP-seq
MIRT2531708	hsa-miR-4459	CLIP-seq
MIRT991913	hsa-miR-4482	CLIP-seq
MIRT2531709	hsa-miR-4484	CLIP-seq
MIRT991914	hsa-miR-4492	CLIP-seq
MIRT991916	hsa-miR-4498	CLIP-seq
MIRT991918	hsa-miR-4505	CLIP-seq
MIRT2531710	hsa-miR-4522	CLIP-seq
MIRT1994199	hsa-miR-4530	CLIP-seq
MIRT991920	hsa-miR-4639-3p	CLIP-seq
MIRT2531711	hsa-miR-4646-5p	CLIP-seq
MIRT1994200	hsa-miR-4649-3p	CLIP-seq
MIRT2531712	hsa-miR-4652-5p	CLIP-seq
MIRT991923	hsa-miR-4656	CLIP-seq
MIRT2531713	hsa-miR-4667-5p	CLIP-seq
MIRT991925	hsa-miR-4675	CLIP-seq
MIRT2531714	hsa-miR-4677-5p	CLIP-seq
MIRT1994201	hsa-miR-4685-5p	CLIP-seq
MIRT1994202	hsa-miR-4690-3p	CLIP-seq
MIRT2531715	hsa-miR-4700-5p	CLIP-seq
MIRT1994204	hsa-miR-4731-3p	CLIP-seq
MIRT991930	hsa-miR-4731-5p	CLIP-seq
MIRT1994205	hsa-miR-4733-3p	CLIP-seq
MIRT991931	hsa-miR-4736	CLIP-seq
MIRT1994206	hsa-miR-4740-3p	CLIP-seq
MIRT991934	hsa-miR-4741	CLIP-seq
MIRT2228154	hsa-miR-4747-5p	CLIP-seq
MIRT991936	hsa-miR-4753-5p	CLIP-seq
MIRT2531716	hsa-miR-4760-3p	CLIP-seq
MIRT2531717	hsa-miR-4768-3p	CLIP-seq
MIRT991939	hsa-miR-4776-3p	CLIP-seq
MIRT1994208	hsa-miR-4801	CLIP-seq
MIRT1994210	hsa-miR-485-5p	CLIP-seq
MIRT991941	hsa-miR-486-3p	CLIP-seq
MIRT2531718	hsa-miR-510	CLIP-seq
MIRT991945	hsa-miR-513a-5p	CLIP-seq
MIRT1994214	hsa-miR-539	CLIP-seq
MIRT2531719	hsa-miR-548a-5p	CLIP-seq
MIRT2531720	hsa-miR-548ab	CLIP-seq
MIRT2531721	hsa-miR-548ak	CLIP-seq
MIRT2531722	hsa-miR-548an	CLIP-seq
MIRT2531723	hsa-miR-548b-5p	CLIP-seq
MIRT2531724	hsa-miR-548c-5p	CLIP-seq
MIRT2531725	hsa-miR-548d-5p	CLIP-seq
MIRT2531726	hsa-miR-548h	CLIP-seq
MIRT2531727	hsa-miR-548i	CLIP-seq
MIRT2531728	hsa-miR-548j	CLIP-seq
MIRT2531729	hsa-miR-548w	CLIP-seq
MIRT2531730	hsa-miR-548y	CLIP-seq
MIRT991958	hsa-miR-551a	CLIP-seq
MIRT991959	hsa-miR-551b	CLIP-seq
MIRT1994215	hsa-miR-552	CLIP-seq
MIRT2531731	hsa-miR-559	CLIP-seq
MIRT2531732	hsa-miR-572	CLIP-seq
MIRT1994216	hsa-miR-612	CLIP-seq
MIRT1994217	hsa-miR-634	CLIP-seq
MIRT991964	hsa-miR-657	CLIP-seq
MIRT2531733	hsa-miR-720	CLIP-seq
MIRT1994218	hsa-miR-761	CLIP-seq
MIRT991966	hsa-miR-762	CLIP-seq
MIRT991967	hsa-miR-764	CLIP-seq
MIRT2531734	hsa-miR-890	CLIP-seq
MIRT1994166	hsa-miR-105	CLIP-seq
MIRT1994167	hsa-miR-1226	CLIP-seq
MIRT1994169	hsa-miR-1285	CLIP-seq
MIRT1994170	hsa-miR-1286	CLIP-seq
MIRT1994174	hsa-miR-198	CLIP-seq
MIRT1994176	hsa-miR-214	CLIP-seq
MIRT1994177	hsa-miR-2467-5p	CLIP-seq
MIRT2228141	hsa-miR-3135b	CLIP-seq
MIRT2531695	hsa-miR-3184	CLIP-seq
MIRT1994182	hsa-miR-3187-5p	CLIP-seq
MIRT1994183	hsa-miR-3188	CLIP-seq
MIRT2531697	hsa-miR-3192	CLIP-seq
MIRT1994184	hsa-miR-320b	CLIP-seq
MIRT1994185	hsa-miR-320c	CLIP-seq
MIRT1994186	hsa-miR-320d	CLIP-seq
MIRT1994187	hsa-miR-320e	CLIP-seq
MIRT2531698	hsa-miR-326	CLIP-seq
MIRT2531699	hsa-miR-330-5p	CLIP-seq
MIRT2531700	hsa-miR-345	CLIP-seq
MIRT1994188	hsa-miR-3619-5p	CLIP-seq
MIRT2531702	hsa-miR-3973	CLIP-seq
MIRT1994195	hsa-miR-3975	CLIP-seq
MIRT2531703	hsa-miR-423-5p	CLIP-seq
MIRT2531704	hsa-miR-4314	CLIP-seq
MIRT2531705	hsa-miR-432	CLIP-seq
MIRT1994197	hsa-miR-4429	CLIP-seq
MIRT1994198	hsa-miR-4457	CLIP-seq
MIRT991914	hsa-miR-4492	CLIP-seq
MIRT991916	hsa-miR-4498	CLIP-seq
MIRT991918	hsa-miR-4505	CLIP-seq
MIRT2531710	hsa-miR-4522	CLIP-seq
MIRT1994199	hsa-miR-4530	CLIP-seq
MIRT2531711	hsa-miR-4646-5p	CLIP-seq
MIRT1994200	hsa-miR-4649-3p	CLIP-seq
MIRT1994201	hsa-miR-4685-5p	CLIP-seq
MIRT1994202	hsa-miR-4690-3p	CLIP-seq
MIRT1994204	hsa-miR-4731-3p	CLIP-seq
MIRT991930	hsa-miR-4731-5p	CLIP-seq
MIRT1994205	hsa-miR-4733-3p	CLIP-seq
MIRT1994206	hsa-miR-4740-3p	CLIP-seq
MIRT2228154	hsa-miR-4747-5p	CLIP-seq
MIRT991939	hsa-miR-4776-3p	CLIP-seq
MIRT1994208	hsa-miR-4801	CLIP-seq
MIRT1994210	hsa-miR-485-5p	CLIP-seq
MIRT991941	hsa-miR-486-3p	CLIP-seq
MIRT2531718	hsa-miR-510	CLIP-seq
MIRT2531719	hsa-miR-548a-5p	CLIP-seq
MIRT2531720	hsa-miR-548ab	CLIP-seq
MIRT2531721	hsa-miR-548ak	CLIP-seq
MIRT2531723	hsa-miR-548b-5p	CLIP-seq
MIRT2531724	hsa-miR-548c-5p	CLIP-seq
MIRT2531725	hsa-miR-548d-5p	CLIP-seq
MIRT2531726	hsa-miR-548h	CLIP-seq
MIRT2531727	hsa-miR-548i	CLIP-seq
MIRT2531728	hsa-miR-548j	CLIP-seq
MIRT2531729	hsa-miR-548w	CLIP-seq
MIRT2531730	hsa-miR-548y	CLIP-seq
MIRT2531731	hsa-miR-559	CLIP-seq
MIRT1994216	hsa-miR-612	CLIP-seq
MIRT1994217	hsa-miR-634	CLIP-seq
MIRT1994218	hsa-miR-761	CLIP-seq
MIRT991966	hsa-miR-762	CLIP-seq
MIRT2531734	hsa-miR-890	CLIP-seq

Gene ontology (GO)

GO ID	Ontology	Definition	Evidence	Reference
GO:0005515	Function	Protein binding	IPI	19412162, 22632967, 33961781
GO:0005737	Component	Cytoplasm	IDA	24828503, 30171069
GO:0005737	Component	Cytoplasm	IEA
GO:0005813	Component	Centrosome	IEA
GO:0005829	Component	Cytosol	TAS
GO:0005856	Component	Cytoskeleton	IEA
GO:0006974	Process	DNA damage response	IDA	19412162, 24936062, 26124108, 30171069
GO:0006974	Process	DNA damage response	IEA
GO:0016567	Process	Protein ubiquitination	IEA
GO:0019005	Component	SCF ubiquitin ligase complex	IBA
GO:0019005	Component	SCF ubiquitin ligase complex	IDA	19412162, 31413110, 39880951
GO:0030330	Process	DNA damage response, signal transduction by p53 class mediator	IDA	29681526
GO:0030332	Function	Cyclin binding	IPI	19412162
GO:0031145	Process	Anaphase-promoting complex-dependent catabolic process	IMP	19412162
GO:0031146	Process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IBA
GO:0031146	Process	SCF-dependent proteasomal ubiquitin-dependent protein catabolic process	IDA	19412162, 24936062, 26124108, 30171069, 39880951
GO:0031571	Process	Mitotic G1 DNA damage checkpoint signaling	IDA	29279382
GO:0031571	Process	Mitotic G1 DNA damage checkpoint signaling	IMP	19412162
GO:0034599	Process	Cellular response to oxidative stress	IDA	39880951
GO:0038066	Process	P38MAPK cascade	IDA	10330143, 11460167
GO:0042770	Process	Signal transduction in response to DNA damage	IDA	24936062
GO:0042770	Process	Signal transduction in response to DNA damage	IDA	24936062
GO:0043025	Component	Neuronal cell body	IEA
GO:0043025	Component	Neuronal cell body	ISS
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	29681526, 39880951
GO:0043161	Process	Proteasome-mediated ubiquitin-dependent protein catabolic process	IDA	24828503, 29279382, 39880951
GO:1901797	Process	Negative regulation of signal transduction by p53 class mediator	IDA	29681526
GO:1990756	Function	Ubiquitin-like ligase-substrate adaptor activity	IDA	19412162, 23469015, 24828503, 24936062, 26124108, 29279382, 30171069, 31413110, 34686346, 39880951, 39894887

Other IDs

• MIM: 609102
• HGNC: 16510
• e!Ensembl: ENSG00000103264

Protein

• UniProt ID: Q5XUX0
• Protein name: F-box only protein 31
• Protein function: Substrate-recognition component of the SCF(FBXO31) protein ligase complex, which specifically mediates the ubiquitination of proteins amidated at their C-terminus in response to oxidative stress, leading to their degradation by the proteasome (P
• PDB: 5VZT, 5VZU
• Family and domains:

  Pfam

  Accession	ID	Position in sequence	Description	Type
  PF12937	F-box-like	67 → 113	F-box-like	Domain

• Tissue specificity: TISSUE SPECIFICITY: Highly expressed in brain. Expressed at moderate levels in most tissues, except bone marrow. {ECO:0000269|PubMed:16357137}.
• Sequence:

  MAVCARLCGVGPSRGCRRRQQRRGPAETAAADSEPDTDPEEERIEASAGVGGGLCAGPSP
  PPPRCSLLELPPELLVEIFASLPGTDLPSLAQVCTKFRRILHTDTIWRRRCREEYGVCEN
  LRKLEITGVSCRDVYAKLLHRYRHILGLWQPDIGPYGGLLNVVVDGLFIIGWMYLPPHDP
  HVDDPMRFKPLFRIHLMERKAATVECMYGHKGPHHGHIQIVKKDEFSTKCNQTDHHRMSG
  GRQEEFRTWLREEWGRTLEDIFHEHMQELILMKFIYTSQYDNCLTYRRIYLPPSRPDDLI
  KPGLFKGTYGSHGLEIVMLSFHGRRARGTKITGDPNIPAGQQTVEIDLRHRIQLPDLENQ
  RNFNELSRIVLEVRERVRQEQQEGGHEAGEGRGRQGPRESQPSPAQPRAEAPSKGPDGTP
  GEDGGEPGDAVAAAEQPAQCGQGQPFVLPVGVSSRNEDYPRTCRMCFYGTGLIAGHGFTS
  PERTPGVFILFDEDRFGFVWLELKSFSLYSRVQATFRNADAPSPQAFDEMLKNIQSLTS

• Sequence length: 539

Pathways

Reactome:

Neddylation
Antigen processing: Ubiquitination & Proteasome degradation

Associated diseases

Causal
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
Ectopic thyroid	Likely pathogenic; Pathogenic	rs2150668444	RCV001849807
Intellectual disability, autosomal recessive 45	Likely pathogenic; Pathogenic	rs2150668444, rs587777703	RCV002468645 RCV000144039
Spastic cerebral palsy	Likely pathogenic; Pathogenic	rs2150668444	RCV001849808

Unknown
Phenotype Name	Clinical Significance	dbSNP ID	RCV Accession
FBXO31-related disorder	Uncertain significance; Likely benign; Benign	rs779067828, rs773284363, rs1907190453, rs762500727, rs752940051, rs201115565, rs142281776, rs75105531, rs149340076, rs144701197	RCV003402416 RCV003405957 RCV003399982 RCV003949723 RCV003949331 RCV003963825 RCV003926271 RCV003983240 RCV003940772 RCV003923060
Malignant tumor of urinary bladder	Uncertain significance	rs2507826304	RCV005932381
Thyroid cancer, nonmedullary, 1	Uncertain significance	rs371015325	RCV005899862

Associations from Text Mining
Disease Name	Relationship Type	References
Carcinoma Hepatocellular	Associate	36803542
Cerebral Palsy	Associate	33675180
Developmental Disabilities	Associate	33675180, 35019165
Esophageal Neoplasms	Associate	31037126
Esophageal Squamous Cell Carcinoma	Associate	33538099
Intellectual Disability	Associate	35019165
Lymphedema distichiasis syndrome	Associate	22407726
Motor Disorders	Associate	33675180
Muscle Spasticity	Associate	33675180
Neoplasms	Inhibit	19412162, 24828503, 26124108, 28500896, 29343641, 30171069, 31413110
Neoplasms	Associate	33538099
Ovarian Neoplasms	Associate	19412162, 24828503
Prostatic Neoplasms	Associate	30627556
Small Cell Lung Carcinoma	Associate	30627556