Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene information from NCBI Gene database. Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways
Entrez ID	79727
Gene name	Lin-28 RNA binding posttranscriptional regulator A
Gene symbol	LIN28A
Synonyms (NCBI Gene)	CSDD1LIN-28LIN28ZCCHC1lin-28A
Chromosome	1
Chromosome location	1p36.11
Summary	This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRN

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miRTarBase ID	miRNA	Experiments	Reference
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	17400653
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	17400653
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	17400653
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	17400653
MIRT003845	hsa-miR-125b-5p	Reporter assay	18230348
MIRT003845	hsa-miR-125b-5p	B-globin reporter assayLuciferase reporter assay	16495412
MIRT003845	hsa-miR-125b-5p	B-globin reporter assayLuciferase reporter assay	16495412
MIRT004801	hsa-let-7a-5p	B-globin reporter assayLuciferase reporter assayMicroarray	16495412
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	16227573
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	16227573
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	16227573
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	16227573
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT004011	hsa-let-7b-5p	Luciferase reporter assay	15131085
MIRT003845	hsa-miR-125b-5p	ImmunoblotLuciferase reporter assayqRT-PCR	22366319
MIRT003845	hsa-miR-125b-5p	ImmunoblotLuciferase reporter assayqRT-PCR	22366319
MIRT003845	hsa-miR-125b-5p	ImmunoblotLuciferase reporter assayqRT-PCR	22366319
MIRT003845	hsa-miR-125b-5p	ImmunoblotLuciferase reporter assayqRT-PCR	22366319
MIRT003845	hsa-miR-125b-5p	ImmunoblotLuciferase reporter assayqRT-PCR	22366319
MIRT003845	hsa-miR-125b-5p	ImmunoblotLuciferase reporter assayqRT-PCR	22366319
MIRT003845	hsa-miR-125b-5p	ImmunoblotNorthern blot	15722555
MIRT004801	hsa-let-7a-5p	ImmunoblotNorthern blot	15722555
MIRT017319	hsa-miR-335-5p	Microarray	18185580
MIRT003738	hsa-miR-125a-5p	Other	16227573
MIRT003845	hsa-miR-125b-5p	Other	16227573
MIRT022327	hsa-miR-124-3p	Microarray	18668037
MIRT029116	hsa-miR-26b-5p	Microarray	19088304
MIRT004011	hsa-let-7b-5p	Reporter assay	15131085
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assayWestern blot	22277001
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assayWestern blot	22277001
MIRT054182	hsa-miR-128-3p	FlowqRT-PCRWestern blot	23019226
MIRT437395	hsa-let-7e-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	23774216
MIRT437395	hsa-let-7e-5p	Luciferase reporter assayMicroarrayqRT-PCRWestern blot	23774216
MIRT437878	hsa-miR-370-3p	Luciferase reporter assay	23729669
MIRT437878	hsa-miR-370-3p	Luciferase reporter assay	23729669
MIRT731576	mmu-let-7a-5p	Luciferase reporter assay	26898455
MIRT731576	mmu-let-7a-5p	Luciferase reporter assay	26898455
MIRT004801	hsa-let-7a-5p	qRT-PCR	25515921
MIRT004801	hsa-let-7a-5p	Luciferase reporter assayImmunohistochemistry (IHC)	33446221
MIRT004011	hsa-let-7b-5p	Luciferase reporter assayqRT-PCR	32697599
MIRT737092	hsa-let-7f-5p	MicroarrayqRT-PCR	32623385
MIRT1110023	hsa-miR-101	CLIP-seq
MIRT1110024	hsa-miR-106a	CLIP-seq
MIRT1110025	hsa-miR-106b	CLIP-seq
MIRT1110026	hsa-miR-1183	CLIP-seq
MIRT1110027	hsa-miR-1197	CLIP-seq
MIRT1110028	hsa-miR-1207-5p	CLIP-seq
MIRT1110029	hsa-miR-1254	CLIP-seq
MIRT1110030	hsa-miR-1262	CLIP-seq
MIRT1110031	hsa-miR-128	CLIP-seq
MIRT1110032	hsa-miR-1283	CLIP-seq
MIRT1110033	hsa-miR-1286	CLIP-seq
MIRT1110034	hsa-miR-1323	CLIP-seq
MIRT1110035	hsa-miR-136	CLIP-seq
MIRT1110036	hsa-miR-142-5p	CLIP-seq
MIRT1110037	hsa-miR-144	CLIP-seq
MIRT1110038	hsa-miR-17	CLIP-seq
MIRT1110039	hsa-miR-20a	CLIP-seq
MIRT1110040	hsa-miR-20b	CLIP-seq
MIRT1110041	hsa-miR-302a	CLIP-seq
MIRT1110042	hsa-miR-302b	CLIP-seq
MIRT1110043	hsa-miR-302c	CLIP-seq
MIRT1110044	hsa-miR-302d	CLIP-seq
MIRT1110045	hsa-miR-302e	CLIP-seq
MIRT1110046	hsa-miR-30a	CLIP-seq
MIRT1110047	hsa-miR-30b	CLIP-seq
MIRT1110048	hsa-miR-30c	CLIP-seq
MIRT1110049	hsa-miR-30d	CLIP-seq
MIRT1110050	hsa-miR-30e	CLIP-seq
MIRT1110051	hsa-miR-3116	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT1110053	hsa-miR-3132	CLIP-seq
MIRT1110054	hsa-miR-3137	CLIP-seq
MIRT1110055	hsa-miR-3155	CLIP-seq
MIRT1110056	hsa-miR-3155b	CLIP-seq
MIRT1110057	hsa-miR-3179	CLIP-seq
MIRT1110058	hsa-miR-3180-5p	CLIP-seq
MIRT1110059	hsa-miR-3202	CLIP-seq
MIRT1110060	hsa-miR-329	CLIP-seq
MIRT1110061	hsa-miR-3614-3p	CLIP-seq
MIRT1110062	hsa-miR-3616-3p	CLIP-seq
MIRT1110063	hsa-miR-3622a-3p	CLIP-seq
MIRT1110064	hsa-miR-3622b-3p	CLIP-seq
MIRT1110065	hsa-miR-362-3p	CLIP-seq
MIRT1110066	hsa-miR-3653	CLIP-seq
MIRT1110067	hsa-miR-3658	CLIP-seq
MIRT1110068	hsa-miR-3661	CLIP-seq
MIRT1110069	hsa-miR-3671	CLIP-seq
MIRT1110070	hsa-miR-3672	CLIP-seq
MIRT1110071	hsa-miR-3690	CLIP-seq
MIRT1110072	hsa-miR-371b-5p	CLIP-seq
MIRT1110073	hsa-miR-372	CLIP-seq
MIRT1110074	hsa-miR-373	CLIP-seq
MIRT1110075	hsa-miR-378g	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT1110077	hsa-miR-3934	CLIP-seq
MIRT1110078	hsa-miR-4252	CLIP-seq
MIRT1110079	hsa-miR-4254	CLIP-seq
MIRT1110080	hsa-miR-4268	CLIP-seq
MIRT1110081	hsa-miR-4271	CLIP-seq
MIRT1110082	hsa-miR-4274	CLIP-seq
MIRT1110083	hsa-miR-4286	CLIP-seq
MIRT1110084	hsa-miR-4297	CLIP-seq
MIRT1110085	hsa-miR-4433	CLIP-seq
MIRT1110086	hsa-miR-4436a	CLIP-seq
MIRT1110087	hsa-miR-4436b-3p	CLIP-seq
MIRT1110088	hsa-miR-4438	CLIP-seq
MIRT1110089	hsa-miR-4448	CLIP-seq
MIRT1110090	hsa-miR-4459	CLIP-seq
MIRT1110091	hsa-miR-4474-3p	CLIP-seq
MIRT1110092	hsa-miR-4519	CLIP-seq
MIRT1110093	hsa-miR-4524	CLIP-seq
MIRT1110094	hsa-miR-4633-3p	CLIP-seq
MIRT1110095	hsa-miR-4638-3p	CLIP-seq
MIRT1110096	hsa-miR-4650-3p	CLIP-seq
MIRT1110097	hsa-miR-4690-5p	CLIP-seq
MIRT1110098	hsa-miR-4701-3p	CLIP-seq
MIRT1110099	hsa-miR-4701-5p	CLIP-seq
MIRT1110100	hsa-miR-4725-3p	CLIP-seq
MIRT1110101	hsa-miR-4731-5p	CLIP-seq
MIRT1110102	hsa-miR-4747-5p	CLIP-seq
MIRT1110103	hsa-miR-4761-5p	CLIP-seq
MIRT1110104	hsa-miR-4763-3p	CLIP-seq
MIRT1110105	hsa-miR-4763-5p	CLIP-seq
MIRT1110106	hsa-miR-4768-3p	CLIP-seq
MIRT1110107	hsa-miR-4786-3p	CLIP-seq
MIRT1110108	hsa-miR-4793-3p	CLIP-seq
MIRT1110109	hsa-miR-4802-3p	CLIP-seq
MIRT1110110	hsa-miR-484	CLIP-seq
MIRT1110111	hsa-miR-489	CLIP-seq
MIRT1110112	hsa-miR-508-5p	CLIP-seq
MIRT1110113	hsa-miR-5095	CLIP-seq
MIRT1110114	hsa-miR-512-3p	CLIP-seq
MIRT1110115	hsa-miR-514	CLIP-seq
MIRT1110116	hsa-miR-514b-3p	CLIP-seq
MIRT1110117	hsa-miR-519d	CLIP-seq
MIRT1110118	hsa-miR-520a-3p	CLIP-seq
MIRT1110119	hsa-miR-520a-5p	CLIP-seq
MIRT1110120	hsa-miR-520b	CLIP-seq
MIRT1110121	hsa-miR-520c-3p	CLIP-seq
MIRT1110122	hsa-miR-520d-3p	CLIP-seq
MIRT1110123	hsa-miR-520d-5p	CLIP-seq
MIRT1110124	hsa-miR-520e	CLIP-seq
MIRT1110125	hsa-miR-520g	CLIP-seq
MIRT1110126	hsa-miR-520h	CLIP-seq
MIRT1110127	hsa-miR-524-5p	CLIP-seq
MIRT1110128	hsa-miR-525-5p	CLIP-seq
MIRT1110129	hsa-miR-541	CLIP-seq
MIRT1110130	hsa-miR-544b	CLIP-seq
MIRT1110131	hsa-miR-548o	CLIP-seq
MIRT1110132	hsa-miR-552	CLIP-seq
MIRT1110133	hsa-miR-558	CLIP-seq
MIRT1110134	hsa-miR-561	CLIP-seq
MIRT1110135	hsa-miR-581	CLIP-seq
MIRT1110136	hsa-miR-583	CLIP-seq
MIRT1110137	hsa-miR-588	CLIP-seq
MIRT1110138	hsa-miR-619	CLIP-seq
MIRT1110139	hsa-miR-631	CLIP-seq
MIRT1110140	hsa-miR-642b	CLIP-seq
MIRT1110141	hsa-miR-654-5p	CLIP-seq
MIRT1110142	hsa-miR-659	CLIP-seq
MIRT1110143	hsa-miR-661	CLIP-seq
MIRT1110144	hsa-miR-663b	CLIP-seq
MIRT1110145	hsa-miR-671-5p	CLIP-seq
MIRT1110146	hsa-miR-766	CLIP-seq
MIRT1110147	hsa-miR-9	CLIP-seq
MIRT1110148	hsa-miR-93	CLIP-seq
MIRT1110024	hsa-miR-106a	CLIP-seq
MIRT1110025	hsa-miR-106b	CLIP-seq
MIRT1110027	hsa-miR-1197	CLIP-seq
MIRT2030644	hsa-miR-122	CLIP-seq
MIRT1110030	hsa-miR-1262	CLIP-seq
MIRT1110031	hsa-miR-128	CLIP-seq
MIRT1110033	hsa-miR-1286	CLIP-seq
MIRT2030645	hsa-miR-145	CLIP-seq
MIRT1110038	hsa-miR-17	CLIP-seq
MIRT2030646	hsa-miR-1827	CLIP-seq
MIRT1110039	hsa-miR-20a	CLIP-seq
MIRT1110040	hsa-miR-20b	CLIP-seq
MIRT1110041	hsa-miR-302a	CLIP-seq
MIRT1110042	hsa-miR-302b	CLIP-seq
MIRT1110043	hsa-miR-302c	CLIP-seq
MIRT1110044	hsa-miR-302d	CLIP-seq
MIRT1110045	hsa-miR-302e	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT2030647	hsa-miR-3135b	CLIP-seq
MIRT2030648	hsa-miR-3154	CLIP-seq
MIRT1110055	hsa-miR-3155	CLIP-seq
MIRT1110056	hsa-miR-3155b	CLIP-seq
MIRT2030649	hsa-miR-34b	CLIP-seq
MIRT1110061	hsa-miR-3614-3p	CLIP-seq
MIRT2030650	hsa-miR-3614-5p	CLIP-seq
MIRT2030651	hsa-miR-3615	CLIP-seq
MIRT2030652	hsa-miR-3652	CLIP-seq
MIRT2030653	hsa-miR-3664-3p	CLIP-seq
MIRT1110070	hsa-miR-3672	CLIP-seq
MIRT2030654	hsa-miR-3688-5p	CLIP-seq
MIRT1110073	hsa-miR-372	CLIP-seq
MIRT1110074	hsa-miR-373	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT2030655	hsa-miR-3929	CLIP-seq
MIRT1110077	hsa-miR-3934	CLIP-seq
MIRT1110084	hsa-miR-4297	CLIP-seq
MIRT2030656	hsa-miR-4419b	CLIP-seq
MIRT2030657	hsa-miR-4430	CLIP-seq
MIRT1110085	hsa-miR-4433	CLIP-seq
MIRT1110086	hsa-miR-4436a	CLIP-seq
MIRT1110087	hsa-miR-4436b-3p	CLIP-seq
MIRT1110088	hsa-miR-4438	CLIP-seq
MIRT1110090	hsa-miR-4459	CLIP-seq
MIRT2030658	hsa-miR-4466	CLIP-seq
MIRT2030659	hsa-miR-4470	CLIP-seq
MIRT2030660	hsa-miR-4478	CLIP-seq
MIRT2030661	hsa-miR-4649-3p	CLIP-seq
MIRT1110097	hsa-miR-4690-5p	CLIP-seq
MIRT2030662	hsa-miR-4695-3p	CLIP-seq
MIRT2030663	hsa-miR-4695-5p	CLIP-seq
MIRT1110098	hsa-miR-4701-3p	CLIP-seq
MIRT2030664	hsa-miR-4712-5p	CLIP-seq
MIRT2030665	hsa-miR-4722-5p	CLIP-seq
MIRT1110101	hsa-miR-4731-5p	CLIP-seq
MIRT1110106	hsa-miR-4768-3p	CLIP-seq
MIRT2030666	hsa-miR-4772-3p	CLIP-seq
MIRT1110110	hsa-miR-484	CLIP-seq
MIRT2030667	hsa-miR-485-5p	CLIP-seq
MIRT2030668	hsa-miR-498	CLIP-seq
MIRT2030669	hsa-miR-501-3p	CLIP-seq
MIRT2030670	hsa-miR-502-3p	CLIP-seq
MIRT1110112	hsa-miR-508-5p	CLIP-seq
MIRT1110113	hsa-miR-5095	CLIP-seq
MIRT2030671	hsa-miR-510	CLIP-seq
MIRT1110114	hsa-miR-512-3p	CLIP-seq
MIRT2030672	hsa-miR-512-5p	CLIP-seq
MIRT1110117	hsa-miR-519d	CLIP-seq
MIRT1110118	hsa-miR-520a-3p	CLIP-seq
MIRT1110120	hsa-miR-520b	CLIP-seq
MIRT1110121	hsa-miR-520c-3p	CLIP-seq
MIRT1110122	hsa-miR-520d-3p	CLIP-seq
MIRT1110124	hsa-miR-520e	CLIP-seq
MIRT1110125	hsa-miR-520g	CLIP-seq
MIRT1110126	hsa-miR-520h	CLIP-seq
MIRT1110132	hsa-miR-552	CLIP-seq
MIRT2030673	hsa-miR-605	CLIP-seq
MIRT1110140	hsa-miR-642b	CLIP-seq
MIRT1110143	hsa-miR-661	CLIP-seq
MIRT2030674	hsa-miR-675	CLIP-seq
MIRT1110146	hsa-miR-766	CLIP-seq
MIRT2030675	hsa-miR-767-5p	CLIP-seq
MIRT2030676	hsa-miR-770-5p	CLIP-seq
MIRT1110148	hsa-miR-93	CLIP-seq
MIRT2030677	hsa-miR-936	CLIP-seq
MIRT2030678	hsa-miR-940	CLIP-seq
MIRT1110024	hsa-miR-106a	CLIP-seq
MIRT1110025	hsa-miR-106b	CLIP-seq
MIRT2030644	hsa-miR-122	CLIP-seq
MIRT1110029	hsa-miR-1254	CLIP-seq
MIRT1110030	hsa-miR-1262	CLIP-seq
MIRT1110031	hsa-miR-128	CLIP-seq
MIRT1110038	hsa-miR-17	CLIP-seq
MIRT2261357	hsa-miR-181a	CLIP-seq
MIRT2261358	hsa-miR-181b	CLIP-seq
MIRT2261359	hsa-miR-181c	CLIP-seq
MIRT2261360	hsa-miR-181d	CLIP-seq
MIRT2030646	hsa-miR-1827	CLIP-seq
MIRT2261361	hsa-miR-1908	CLIP-seq
MIRT1110039	hsa-miR-20a	CLIP-seq
MIRT1110040	hsa-miR-20b	CLIP-seq
MIRT1110041	hsa-miR-302a	CLIP-seq
MIRT1110042	hsa-miR-302b	CLIP-seq
MIRT1110043	hsa-miR-302c	CLIP-seq
MIRT1110044	hsa-miR-302d	CLIP-seq
MIRT1110045	hsa-miR-302e	CLIP-seq
MIRT1110051	hsa-miR-3116	CLIP-seq
MIRT2261362	hsa-miR-3117-3p	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT2030647	hsa-miR-3135b	CLIP-seq
MIRT2261363	hsa-miR-3140-5p	CLIP-seq
MIRT2261364	hsa-miR-3159	CLIP-seq
MIRT2261365	hsa-miR-3169	CLIP-seq
MIRT1110058	hsa-miR-3180-5p	CLIP-seq
MIRT2261366	hsa-miR-3194-3p	CLIP-seq
MIRT2030649	hsa-miR-34b	CLIP-seq
MIRT2261367	hsa-miR-3607-3p	CLIP-seq
MIRT1110061	hsa-miR-3614-3p	CLIP-seq
MIRT2030650	hsa-miR-3614-5p	CLIP-seq
MIRT1110063	hsa-miR-3622a-3p	CLIP-seq
MIRT1110064	hsa-miR-3622b-3p	CLIP-seq
MIRT2030652	hsa-miR-3652	CLIP-seq
MIRT2261368	hsa-miR-3656	CLIP-seq
MIRT2030653	hsa-miR-3664-3p	CLIP-seq
MIRT1110070	hsa-miR-3672	CLIP-seq
MIRT2261369	hsa-miR-3686	CLIP-seq
MIRT1110071	hsa-miR-3690	CLIP-seq
MIRT1110073	hsa-miR-372	CLIP-seq
MIRT1110074	hsa-miR-373	CLIP-seq
MIRT1110075	hsa-miR-378g	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT2030655	hsa-miR-3929	CLIP-seq
MIRT1110077	hsa-miR-3934	CLIP-seq
MIRT1110078	hsa-miR-4252	CLIP-seq
MIRT2261370	hsa-miR-4262	CLIP-seq
MIRT1110082	hsa-miR-4274	CLIP-seq
MIRT1110084	hsa-miR-4297	CLIP-seq
MIRT2261371	hsa-miR-431	CLIP-seq
MIRT2030656	hsa-miR-4419b	CLIP-seq
MIRT2261372	hsa-miR-4427	CLIP-seq
MIRT2030657	hsa-miR-4430	CLIP-seq
MIRT1110085	hsa-miR-4433	CLIP-seq
MIRT1110090	hsa-miR-4459	CLIP-seq
MIRT2030658	hsa-miR-4466	CLIP-seq
MIRT2030660	hsa-miR-4478	CLIP-seq
MIRT1110092	hsa-miR-4519	CLIP-seq
MIRT1110093	hsa-miR-4524	CLIP-seq
MIRT2261373	hsa-miR-4537	CLIP-seq
MIRT1110095	hsa-miR-4638-3p	CLIP-seq
MIRT2030661	hsa-miR-4649-3p	CLIP-seq
MIRT2261374	hsa-miR-4653-3p	CLIP-seq
MIRT2030662	hsa-miR-4695-3p	CLIP-seq
MIRT2030663	hsa-miR-4695-5p	CLIP-seq
MIRT1110098	hsa-miR-4701-3p	CLIP-seq
MIRT2261375	hsa-miR-4707-3p	CLIP-seq
MIRT2030665	hsa-miR-4722-5p	CLIP-seq
MIRT1110101	hsa-miR-4731-5p	CLIP-seq
MIRT2261376	hsa-miR-4735-5p	CLIP-seq
MIRT1110102	hsa-miR-4747-5p	CLIP-seq
MIRT2261377	hsa-miR-4759	CLIP-seq
MIRT1110103	hsa-miR-4761-5p	CLIP-seq
MIRT1110106	hsa-miR-4768-3p	CLIP-seq
MIRT2030666	hsa-miR-4772-3p	CLIP-seq
MIRT2261378	hsa-miR-4775	CLIP-seq
MIRT1110107	hsa-miR-4786-3p	CLIP-seq
MIRT1110108	hsa-miR-4793-3p	CLIP-seq
MIRT1110109	hsa-miR-4802-3p	CLIP-seq
MIRT2030667	hsa-miR-485-5p	CLIP-seq
MIRT1110112	hsa-miR-508-5p	CLIP-seq
MIRT1110113	hsa-miR-5095	CLIP-seq
MIRT2030671	hsa-miR-510	CLIP-seq
MIRT1110114	hsa-miR-512-3p	CLIP-seq
MIRT2030672	hsa-miR-512-5p	CLIP-seq
MIRT1110117	hsa-miR-519d	CLIP-seq
MIRT1110118	hsa-miR-520a-3p	CLIP-seq
MIRT1110119	hsa-miR-520a-5p	CLIP-seq
MIRT1110120	hsa-miR-520b	CLIP-seq
MIRT1110121	hsa-miR-520c-3p	CLIP-seq
MIRT1110122	hsa-miR-520d-3p	CLIP-seq
MIRT1110124	hsa-miR-520e	CLIP-seq
MIRT1110125	hsa-miR-520g	CLIP-seq
MIRT1110126	hsa-miR-520h	CLIP-seq
MIRT1110128	hsa-miR-525-5p	CLIP-seq
MIRT1110129	hsa-miR-541	CLIP-seq
MIRT1110130	hsa-miR-544b	CLIP-seq
MIRT2261379	hsa-miR-550a	CLIP-seq
MIRT1110132	hsa-miR-552	CLIP-seq
MIRT2261380	hsa-miR-590-3p	CLIP-seq
MIRT2261381	hsa-miR-615-5p	CLIP-seq
MIRT1110140	hsa-miR-642b	CLIP-seq
MIRT1110141	hsa-miR-654-5p	CLIP-seq
MIRT1110142	hsa-miR-659	CLIP-seq
MIRT1110143	hsa-miR-661	CLIP-seq
MIRT2261382	hsa-miR-663	CLIP-seq
MIRT1110145	hsa-miR-671-5p	CLIP-seq
MIRT2030674	hsa-miR-675	CLIP-seq
MIRT1110146	hsa-miR-766	CLIP-seq
MIRT1110147	hsa-miR-9	CLIP-seq
MIRT2261383	hsa-miR-924	CLIP-seq
MIRT1110148	hsa-miR-93	CLIP-seq
MIRT2030678	hsa-miR-940	CLIP-seq
MIRT2390154	hsa-miR-10a	CLIP-seq
MIRT2390155	hsa-miR-10b	CLIP-seq
MIRT1110029	hsa-miR-1254	CLIP-seq
MIRT1110051	hsa-miR-3116	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT1110058	hsa-miR-3180-5p	CLIP-seq
MIRT1110060	hsa-miR-329	CLIP-seq
MIRT2390156	hsa-miR-3620	CLIP-seq
MIRT1110063	hsa-miR-3622a-3p	CLIP-seq
MIRT1110064	hsa-miR-3622b-3p	CLIP-seq
MIRT1110065	hsa-miR-362-3p	CLIP-seq
MIRT2030654	hsa-miR-3688-5p	CLIP-seq
MIRT1110071	hsa-miR-3690	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT1110085	hsa-miR-4433	CLIP-seq
MIRT1110090	hsa-miR-4459	CLIP-seq
MIRT1110095	hsa-miR-4638-3p	CLIP-seq
MIRT1110102	hsa-miR-4747-5p	CLIP-seq
MIRT1110103	hsa-miR-4761-5p	CLIP-seq
MIRT1110106	hsa-miR-4768-3p	CLIP-seq
MIRT1110107	hsa-miR-4786-3p	CLIP-seq
MIRT1110119	hsa-miR-520a-5p	CLIP-seq
MIRT1110123	hsa-miR-520d-5p	CLIP-seq
MIRT1110127	hsa-miR-524-5p	CLIP-seq
MIRT1110128	hsa-miR-525-5p	CLIP-seq
MIRT1110129	hsa-miR-541	CLIP-seq
MIRT1110141	hsa-miR-654-5p	CLIP-seq
MIRT1110145	hsa-miR-671-5p	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT2453057	hsa-miR-3659	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT2453058	hsa-miR-4658	CLIP-seq
MIRT2453059	hsa-miR-4684-5p	CLIP-seq
MIRT1110102	hsa-miR-4747-5p	CLIP-seq
MIRT1110103	hsa-miR-4761-5p	CLIP-seq
MIRT1110107	hsa-miR-4786-3p	CLIP-seq
MIRT1110129	hsa-miR-541	CLIP-seq
MIRT2453060	hsa-miR-548c-3p	CLIP-seq
MIRT2453061	hsa-miR-574-5p	CLIP-seq
MIRT2453062	hsa-miR-644	CLIP-seq
MIRT1110141	hsa-miR-654-5p	CLIP-seq
MIRT1110145	hsa-miR-671-5p	CLIP-seq
MIRT2030644	hsa-miR-122	CLIP-seq
MIRT2561379	hsa-miR-1237	CLIP-seq
MIRT2561380	hsa-miR-1248	CLIP-seq
MIRT2561381	hsa-miR-129-5p	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT2030647	hsa-miR-3135b	CLIP-seq
MIRT2561382	hsa-miR-3149	CLIP-seq
MIRT2030651	hsa-miR-3615	CLIP-seq
MIRT1110063	hsa-miR-3622a-3p	CLIP-seq
MIRT1110064	hsa-miR-3622b-3p	CLIP-seq
MIRT2561383	hsa-miR-3622b-5p	CLIP-seq
MIRT2561384	hsa-miR-362-5p	CLIP-seq
MIRT2030652	hsa-miR-3652	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT2561385	hsa-miR-411	CLIP-seq
MIRT2030657	hsa-miR-4430	CLIP-seq
MIRT2030658	hsa-miR-4466	CLIP-seq
MIRT2030662	hsa-miR-4695-3p	CLIP-seq
MIRT2261376	hsa-miR-4735-5p	CLIP-seq
MIRT1110102	hsa-miR-4747-5p	CLIP-seq
MIRT1110103	hsa-miR-4761-5p	CLIP-seq
MIRT2030666	hsa-miR-4772-3p	CLIP-seq
MIRT2261378	hsa-miR-4775	CLIP-seq
MIRT1110107	hsa-miR-4786-3p	CLIP-seq
MIRT2561386	hsa-miR-4795-3p	CLIP-seq
MIRT2030668	hsa-miR-498	CLIP-seq
MIRT2561387	hsa-miR-500b	CLIP-seq
MIRT2561388	hsa-miR-501-5p	CLIP-seq
MIRT1110129	hsa-miR-541	CLIP-seq
MIRT2261380	hsa-miR-590-3p	CLIP-seq
MIRT1110141	hsa-miR-654-5p	CLIP-seq
MIRT1110145	hsa-miR-671-5p	CLIP-seq
MIRT2030674	hsa-miR-675	CLIP-seq
MIRT2561389	hsa-miR-941	CLIP-seq
MIRT2561390	hsa-miR-944	CLIP-seq
MIRT2030644	hsa-miR-122	CLIP-seq
MIRT2561379	hsa-miR-1237	CLIP-seq
MIRT2561380	hsa-miR-1248	CLIP-seq
MIRT2561381	hsa-miR-129-5p	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT2030647	hsa-miR-3135b	CLIP-seq
MIRT2561382	hsa-miR-3149	CLIP-seq
MIRT2030651	hsa-miR-3615	CLIP-seq
MIRT2561383	hsa-miR-3622b-5p	CLIP-seq
MIRT2561384	hsa-miR-362-5p	CLIP-seq
MIRT2030652	hsa-miR-3652	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT2030657	hsa-miR-4430	CLIP-seq
MIRT1110085	hsa-miR-4433	CLIP-seq
MIRT1110090	hsa-miR-4459	CLIP-seq
MIRT2030658	hsa-miR-4466	CLIP-seq
MIRT2030662	hsa-miR-4695-3p	CLIP-seq
MIRT2261376	hsa-miR-4735-5p	CLIP-seq
MIRT1110102	hsa-miR-4747-5p	CLIP-seq
MIRT1110103	hsa-miR-4761-5p	CLIP-seq
MIRT1110106	hsa-miR-4768-3p	CLIP-seq
MIRT2030666	hsa-miR-4772-3p	CLIP-seq
MIRT2261378	hsa-miR-4775	CLIP-seq
MIRT1110107	hsa-miR-4786-3p	CLIP-seq
MIRT2561386	hsa-miR-4795-3p	CLIP-seq
MIRT2561387	hsa-miR-500b	CLIP-seq
MIRT2561388	hsa-miR-501-5p	CLIP-seq
MIRT1110129	hsa-miR-541	CLIP-seq
MIRT2261380	hsa-miR-590-3p	CLIP-seq
MIRT1110141	hsa-miR-654-5p	CLIP-seq
MIRT1110145	hsa-miR-671-5p	CLIP-seq
MIRT2030674	hsa-miR-675	CLIP-seq
MIRT2561389	hsa-miR-941	CLIP-seq
MIRT2561390	hsa-miR-944	CLIP-seq

3

Show/Hide all (3)

Transcription factor	Regulation	Reference
KAT2B	Unknown	24631505
REST	Repression	22532168
SIRT1	Unknown	24631505

66

Show/Hide all (66)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000932	Component	P-body	IDA	17617744
GO:0000932	Component	P-body	IEA
GO:0002151	Function	G-quadruplex RNA binding	IEA
GO:0002151	Function	G-quadruplex RNA binding	ISS
GO:0003676	Function	Nucleic acid binding	IEA
GO:0003723	Function	RNA binding	IDA	19703396
GO:0003723	Function	RNA binding	IEA
GO:0003729	Function	MRNA binding	IBA
GO:0003729	Function	MRNA binding	IDA	21247876
GO:0003729	Function	MRNA binding	IEA
GO:0005515	Function	Protein binding	IPI	19703396, 21247876, 32296183, 32814053
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IDA	17617744
GO:0005634	Component	Nucleus	IEA
GO:0005730	Component	Nucleolus	IDA
GO:0005730	Component	Nucleolus	IEA
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IDA	18604195, 20014101, 21247876
GO:0005737	Component	Cytoplasm	IEA
GO:0005783	Component	Endoplasmic reticulum	IEA
GO:0005791	Component	Rough endoplasmic reticulum	IEA
GO:0005791	Component	Rough endoplasmic reticulum	ISS
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0007281	Process	Germ cell development	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0010494	Component	Cytoplasmic stress granule	IDA	17617744
GO:0010494	Component	Cytoplasmic stress granule	IEA
GO:0010586	Process	MiRNA metabolic process	IEA
GO:0010587	Process	MiRNA catabolic process	IEA
GO:0010587	Process	MiRNA catabolic process	IMP	19703396
GO:0010587	Process	MiRNA catabolic process	ISS
GO:0010608	Process	Post-transcriptional regulation of gene expression	IEA
GO:0017148	Process	Negative regulation of translation	IEA
GO:0017148	Process	Negative regulation of translation	ISS
GO:0019827	Process	Stem cell population maintenance	IMP	19703396
GO:0031047	Process	Regulatory ncRNA-mediated gene silencing	IEA
GO:0031054	Process	Pre-miRNA processing	IBA
GO:0031054	Process	Pre-miRNA processing	IEA
GO:0031054	Process	Pre-miRNA processing	IEA
GO:0031054	Process	Pre-miRNA processing	IMP	19703396
GO:0031123	Process	RNA 3'-end processing	IEA
GO:0031123	Process	RNA 3'-end processing	IMP	19703396
GO:0031369	Function	Translation initiation factor binding	IEA
GO:0032008	Process	Positive regulation of TOR signaling	IEA
GO:0032008	Process	Positive regulation of TOR signaling	ISS
GO:0035198	Function	MiRNA binding	IEA
GO:0035198	Function	MiRNA binding	ISS
GO:0045666	Process	Positive regulation of neuron differentiation	IEA
GO:0045686	Process	Negative regulation of glial cell differentiation	IEA
GO:0045727	Process	Positive regulation of translation	IEA
GO:0046872	Function	Metal ion binding	IEA
GO:0048863	Process	Stem cell differentiation	IEA
GO:0051897	Process	Positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	IEA
GO:0051897	Process	Positive regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction	ISS
GO:0060964	Process	Regulation of miRNA-mediated gene silencing	IEA
GO:0070883	Function	Pre-miRNA binding	IDA	21247876
GO:0071333	Process	Cellular response to glucose stimulus	IEA
GO:0071333	Process	Cellular response to glucose stimulus	ISS
GO:0140517	Function	Protein-RNA adaptor activity	IDA	18951094
GO:1901724	Process	Positive regulation of cell proliferation involved in kidney development	IEA
GO:1990825	Function	Sequence-specific mRNA binding	IEA
GO:1990825	Function	Sequence-specific mRNA binding	ISS
GO:2000632	Process	Negative regulation of pre-miRNA processing	IDA	21247876
GO:2000632	Process	Negative regulation of pre-miRNA processing	IEA
GO:2000767	Process	Positive regulation of cytoplasmic translation	IMP	21247876

MIM	HGNC	e!Ensembl
611043	15986	ENSG00000131914

Protein name

Protein lin-28 homolog A (Lin-28A) (Zinc finger CCHC domain-containing protein 1)

Protein function

RNA-binding protein that inhibits processing of pre-let-7 miRNAs and regulates translation of mRNAs that control developmental timing, pluripotency and metabolism (PubMed:21247876). Seems to recognize a common structural G-quartet (G4) feature i

PDB

2CQF , 2LI8 , 5UDZ , 8OPS , 8OPT , 8OST

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00313	CSD	40 → 112		Domain
PF00098	zf-CCHC	137 → 154	Zinc knuckle	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in embryonic stem cells, placenta and testis. Tends to be up-regulated in HER2-overexpressing breast tumors. {ECO:0000269|PubMed:14688391, ECO:0000269|PubMed:15614775, ECO:0000269|PubMed:15722555, ECO:0000269|PubMed:22118463}

Sequence

MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTA
RAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGS
ERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQ
GPSAQGKPTYFREEEEEIHSPTLLPEAQN

Sequence length

209

Interactions

View interactions

	Reactome
			Transcriptional regulation of pluripotent stem cells