Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Transcription factors Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	79727
Gene name Gene Name - the full gene name approved by the HGNC.	Lin-28 RNA binding posttranscriptional regulator A
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	LIN28A
Synonyms (NCBI Gene) Gene synonyms aliases	CSDD1, LIN-28, LIN28, ZCCHC1, lin-28A
Chromosome Chromosome number	1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	1p36.11
Summary Summary of gene provided in NCBI Entrez Gene.	This gene encodes a LIN-28 family RNA-binding protein that acts as a posttranscriptional regulator of genes involved in developmental timing and self-renewal in embryonic stem cells. The encoded protein functions through direct interaction with target mRN

Show/Hide all(489)

miRTarBase ID	miRNA	Experiments	Reference
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	17400653
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	17400653
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	17400653
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	17400653
MIRT003845	hsa-miR-125b-5p	Reporter assay	18230348
MIRT003845	hsa-miR-125b-5p	B-globin reporter assay, Luciferase reporter assay	16495412
MIRT003845	hsa-miR-125b-5p	B-globin reporter assay, Luciferase reporter assay	16495412
MIRT004801	hsa-let-7a-5p	B-globin reporter assay, Luciferase reporter assay, Microarray	16495412
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	16227573
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	16227573
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	16227573
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	16227573
MIRT003738	hsa-miR-125a-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay	16227573
MIRT004011	hsa-let-7b-5p	Luciferase reporter assay	15131085
MIRT003845	hsa-miR-125b-5p	Immunoblot, Luciferase reporter assay, qRT-PCR	22366319
MIRT003845	hsa-miR-125b-5p	Immunoblot, Luciferase reporter assay, qRT-PCR	22366319
MIRT003845	hsa-miR-125b-5p	Immunoblot, Luciferase reporter assay, qRT-PCR	22366319
MIRT003845	hsa-miR-125b-5p	Immunoblot, Luciferase reporter assay, qRT-PCR	22366319
MIRT003845	hsa-miR-125b-5p	Immunoblot, Luciferase reporter assay, qRT-PCR	22366319
MIRT003845	hsa-miR-125b-5p	Immunoblot, Luciferase reporter assay, qRT-PCR	22366319
MIRT003845	hsa-miR-125b-5p	Immunoblot, Northern blot	15722555
MIRT004801	hsa-let-7a-5p	Immunoblot, Northern blot	15722555
MIRT017319	hsa-miR-335-5p	Microarray	18185580
MIRT003738	hsa-miR-125a-5p	Other	16227573
MIRT003845	hsa-miR-125b-5p	Other	16227573
MIRT022327	hsa-miR-124-3p	Microarray	18668037
MIRT029116	hsa-miR-26b-5p	Microarray	19088304
MIRT004011	hsa-let-7b-5p	Reporter assay	15131085
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	22277001
MIRT003845	hsa-miR-125b-5p	Luciferase reporter assay, Western blot	22277001
MIRT054182	hsa-miR-128-3p	Flow, qRT-PCR, Western blot	23019226
MIRT437395	hsa-let-7e-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	23774216
MIRT437395	hsa-let-7e-5p	Luciferase reporter assay, Microarray, qRT-PCR, Western blot	23774216
MIRT437878	hsa-miR-370-3p	Luciferase reporter assay	23729669
MIRT437878	hsa-miR-370-3p	Luciferase reporter assay	23729669
MIRT731576	mmu-let-7a-5p	Luciferase reporter assay	26898455
MIRT731576	mmu-let-7a-5p	Luciferase reporter assay	26898455
MIRT004801	hsa-let-7a-5p	qRT-PCR	25515921
MIRT004801	hsa-let-7a-5p	Luciferase reporter assay, Immunohistochemistry (IHC)	33446221
MIRT004011	hsa-let-7b-5p	Luciferase reporter assay, qRT-PCR	32697599
MIRT737092	hsa-let-7f-5p	Microarray, qRT-PCR	32623385
MIRT1110023	hsa-miR-101	CLIP-seq
MIRT1110024	hsa-miR-106a	CLIP-seq
MIRT1110025	hsa-miR-106b	CLIP-seq
MIRT1110026	hsa-miR-1183	CLIP-seq
MIRT1110027	hsa-miR-1197	CLIP-seq
MIRT1110028	hsa-miR-1207-5p	CLIP-seq
MIRT1110029	hsa-miR-1254	CLIP-seq
MIRT1110030	hsa-miR-1262	CLIP-seq
MIRT1110031	hsa-miR-128	CLIP-seq
MIRT1110032	hsa-miR-1283	CLIP-seq
MIRT1110033	hsa-miR-1286	CLIP-seq
MIRT1110034	hsa-miR-1323	CLIP-seq
MIRT1110035	hsa-miR-136	CLIP-seq
MIRT1110036	hsa-miR-142-5p	CLIP-seq
MIRT1110037	hsa-miR-144	CLIP-seq
MIRT1110038	hsa-miR-17	CLIP-seq
MIRT1110039	hsa-miR-20a	CLIP-seq
MIRT1110040	hsa-miR-20b	CLIP-seq
MIRT1110041	hsa-miR-302a	CLIP-seq
MIRT1110042	hsa-miR-302b	CLIP-seq
MIRT1110043	hsa-miR-302c	CLIP-seq
MIRT1110044	hsa-miR-302d	CLIP-seq
MIRT1110045	hsa-miR-302e	CLIP-seq
MIRT1110046	hsa-miR-30a	CLIP-seq
MIRT1110047	hsa-miR-30b	CLIP-seq
MIRT1110048	hsa-miR-30c	CLIP-seq
MIRT1110049	hsa-miR-30d	CLIP-seq
MIRT1110050	hsa-miR-30e	CLIP-seq
MIRT1110051	hsa-miR-3116	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT1110053	hsa-miR-3132	CLIP-seq
MIRT1110054	hsa-miR-3137	CLIP-seq
MIRT1110055	hsa-miR-3155	CLIP-seq
MIRT1110056	hsa-miR-3155b	CLIP-seq
MIRT1110057	hsa-miR-3179	CLIP-seq
MIRT1110058	hsa-miR-3180-5p	CLIP-seq
MIRT1110059	hsa-miR-3202	CLIP-seq
MIRT1110060	hsa-miR-329	CLIP-seq
MIRT1110061	hsa-miR-3614-3p	CLIP-seq
MIRT1110062	hsa-miR-3616-3p	CLIP-seq
MIRT1110063	hsa-miR-3622a-3p	CLIP-seq
MIRT1110064	hsa-miR-3622b-3p	CLIP-seq
MIRT1110065	hsa-miR-362-3p	CLIP-seq
MIRT1110066	hsa-miR-3653	CLIP-seq
MIRT1110067	hsa-miR-3658	CLIP-seq
MIRT1110068	hsa-miR-3661	CLIP-seq
MIRT1110069	hsa-miR-3671	CLIP-seq
MIRT1110070	hsa-miR-3672	CLIP-seq
MIRT1110071	hsa-miR-3690	CLIP-seq
MIRT1110072	hsa-miR-371b-5p	CLIP-seq
MIRT1110073	hsa-miR-372	CLIP-seq
MIRT1110074	hsa-miR-373	CLIP-seq
MIRT1110075	hsa-miR-378g	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT1110077	hsa-miR-3934	CLIP-seq
MIRT1110078	hsa-miR-4252	CLIP-seq
MIRT1110079	hsa-miR-4254	CLIP-seq
MIRT1110080	hsa-miR-4268	CLIP-seq
MIRT1110081	hsa-miR-4271	CLIP-seq
MIRT1110082	hsa-miR-4274	CLIP-seq
MIRT1110083	hsa-miR-4286	CLIP-seq
MIRT1110084	hsa-miR-4297	CLIP-seq
MIRT1110085	hsa-miR-4433	CLIP-seq
MIRT1110086	hsa-miR-4436a	CLIP-seq
MIRT1110087	hsa-miR-4436b-3p	CLIP-seq
MIRT1110088	hsa-miR-4438	CLIP-seq
MIRT1110089	hsa-miR-4448	CLIP-seq
MIRT1110090	hsa-miR-4459	CLIP-seq
MIRT1110091	hsa-miR-4474-3p	CLIP-seq
MIRT1110092	hsa-miR-4519	CLIP-seq
MIRT1110093	hsa-miR-4524	CLIP-seq
MIRT1110094	hsa-miR-4633-3p	CLIP-seq
MIRT1110095	hsa-miR-4638-3p	CLIP-seq
MIRT1110096	hsa-miR-4650-3p	CLIP-seq
MIRT1110097	hsa-miR-4690-5p	CLIP-seq
MIRT1110098	hsa-miR-4701-3p	CLIP-seq
MIRT1110099	hsa-miR-4701-5p	CLIP-seq
MIRT1110100	hsa-miR-4725-3p	CLIP-seq
MIRT1110101	hsa-miR-4731-5p	CLIP-seq
MIRT1110102	hsa-miR-4747-5p	CLIP-seq
MIRT1110103	hsa-miR-4761-5p	CLIP-seq
MIRT1110104	hsa-miR-4763-3p	CLIP-seq
MIRT1110105	hsa-miR-4763-5p	CLIP-seq
MIRT1110106	hsa-miR-4768-3p	CLIP-seq
MIRT1110107	hsa-miR-4786-3p	CLIP-seq
MIRT1110108	hsa-miR-4793-3p	CLIP-seq
MIRT1110109	hsa-miR-4802-3p	CLIP-seq
MIRT1110110	hsa-miR-484	CLIP-seq
MIRT1110111	hsa-miR-489	CLIP-seq
MIRT1110112	hsa-miR-508-5p	CLIP-seq
MIRT1110113	hsa-miR-5095	CLIP-seq
MIRT1110114	hsa-miR-512-3p	CLIP-seq
MIRT1110115	hsa-miR-514	CLIP-seq
MIRT1110116	hsa-miR-514b-3p	CLIP-seq
MIRT1110117	hsa-miR-519d	CLIP-seq
MIRT1110118	hsa-miR-520a-3p	CLIP-seq
MIRT1110119	hsa-miR-520a-5p	CLIP-seq
MIRT1110120	hsa-miR-520b	CLIP-seq
MIRT1110121	hsa-miR-520c-3p	CLIP-seq
MIRT1110122	hsa-miR-520d-3p	CLIP-seq
MIRT1110123	hsa-miR-520d-5p	CLIP-seq
MIRT1110124	hsa-miR-520e	CLIP-seq
MIRT1110125	hsa-miR-520g	CLIP-seq
MIRT1110126	hsa-miR-520h	CLIP-seq
MIRT1110127	hsa-miR-524-5p	CLIP-seq
MIRT1110128	hsa-miR-525-5p	CLIP-seq
MIRT1110129	hsa-miR-541	CLIP-seq
MIRT1110130	hsa-miR-544b	CLIP-seq
MIRT1110131	hsa-miR-548o	CLIP-seq
MIRT1110132	hsa-miR-552	CLIP-seq
MIRT1110133	hsa-miR-558	CLIP-seq
MIRT1110134	hsa-miR-561	CLIP-seq
MIRT1110135	hsa-miR-581	CLIP-seq
MIRT1110136	hsa-miR-583	CLIP-seq
MIRT1110137	hsa-miR-588	CLIP-seq
MIRT1110138	hsa-miR-619	CLIP-seq
MIRT1110139	hsa-miR-631	CLIP-seq
MIRT1110140	hsa-miR-642b	CLIP-seq
MIRT1110141	hsa-miR-654-5p	CLIP-seq
MIRT1110142	hsa-miR-659	CLIP-seq
MIRT1110143	hsa-miR-661	CLIP-seq
MIRT1110144	hsa-miR-663b	CLIP-seq
MIRT1110145	hsa-miR-671-5p	CLIP-seq
MIRT1110146	hsa-miR-766	CLIP-seq
MIRT1110147	hsa-miR-9	CLIP-seq
MIRT1110148	hsa-miR-93	CLIP-seq
MIRT1110024	hsa-miR-106a	CLIP-seq
MIRT1110025	hsa-miR-106b	CLIP-seq
MIRT1110027	hsa-miR-1197	CLIP-seq
MIRT2030644	hsa-miR-122	CLIP-seq
MIRT1110030	hsa-miR-1262	CLIP-seq
MIRT1110031	hsa-miR-128	CLIP-seq
MIRT1110033	hsa-miR-1286	CLIP-seq
MIRT2030645	hsa-miR-145	CLIP-seq
MIRT1110038	hsa-miR-17	CLIP-seq
MIRT2030646	hsa-miR-1827	CLIP-seq
MIRT1110039	hsa-miR-20a	CLIP-seq
MIRT1110040	hsa-miR-20b	CLIP-seq
MIRT1110041	hsa-miR-302a	CLIP-seq
MIRT1110042	hsa-miR-302b	CLIP-seq
MIRT1110043	hsa-miR-302c	CLIP-seq
MIRT1110044	hsa-miR-302d	CLIP-seq
MIRT1110045	hsa-miR-302e	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT2030647	hsa-miR-3135b	CLIP-seq
MIRT2030648	hsa-miR-3154	CLIP-seq
MIRT1110055	hsa-miR-3155	CLIP-seq
MIRT1110056	hsa-miR-3155b	CLIP-seq
MIRT2030649	hsa-miR-34b	CLIP-seq
MIRT1110061	hsa-miR-3614-3p	CLIP-seq
MIRT2030650	hsa-miR-3614-5p	CLIP-seq
MIRT2030651	hsa-miR-3615	CLIP-seq
MIRT2030652	hsa-miR-3652	CLIP-seq
MIRT2030653	hsa-miR-3664-3p	CLIP-seq
MIRT1110070	hsa-miR-3672	CLIP-seq
MIRT2030654	hsa-miR-3688-5p	CLIP-seq
MIRT1110073	hsa-miR-372	CLIP-seq
MIRT1110074	hsa-miR-373	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT2030655	hsa-miR-3929	CLIP-seq
MIRT1110077	hsa-miR-3934	CLIP-seq
MIRT1110084	hsa-miR-4297	CLIP-seq
MIRT2030656	hsa-miR-4419b	CLIP-seq
MIRT2030657	hsa-miR-4430	CLIP-seq
MIRT1110085	hsa-miR-4433	CLIP-seq
MIRT1110086	hsa-miR-4436a	CLIP-seq
MIRT1110087	hsa-miR-4436b-3p	CLIP-seq
MIRT1110088	hsa-miR-4438	CLIP-seq
MIRT1110090	hsa-miR-4459	CLIP-seq
MIRT2030658	hsa-miR-4466	CLIP-seq
MIRT2030659	hsa-miR-4470	CLIP-seq
MIRT2030660	hsa-miR-4478	CLIP-seq
MIRT2030661	hsa-miR-4649-3p	CLIP-seq
MIRT1110097	hsa-miR-4690-5p	CLIP-seq
MIRT2030662	hsa-miR-4695-3p	CLIP-seq
MIRT2030663	hsa-miR-4695-5p	CLIP-seq
MIRT1110098	hsa-miR-4701-3p	CLIP-seq
MIRT2030664	hsa-miR-4712-5p	CLIP-seq
MIRT2030665	hsa-miR-4722-5p	CLIP-seq
MIRT1110101	hsa-miR-4731-5p	CLIP-seq
MIRT1110106	hsa-miR-4768-3p	CLIP-seq
MIRT2030666	hsa-miR-4772-3p	CLIP-seq
MIRT1110110	hsa-miR-484	CLIP-seq
MIRT2030667	hsa-miR-485-5p	CLIP-seq
MIRT2030668	hsa-miR-498	CLIP-seq
MIRT2030669	hsa-miR-501-3p	CLIP-seq
MIRT2030670	hsa-miR-502-3p	CLIP-seq
MIRT1110112	hsa-miR-508-5p	CLIP-seq
MIRT1110113	hsa-miR-5095	CLIP-seq
MIRT2030671	hsa-miR-510	CLIP-seq
MIRT1110114	hsa-miR-512-3p	CLIP-seq
MIRT2030672	hsa-miR-512-5p	CLIP-seq
MIRT1110117	hsa-miR-519d	CLIP-seq
MIRT1110118	hsa-miR-520a-3p	CLIP-seq
MIRT1110120	hsa-miR-520b	CLIP-seq
MIRT1110121	hsa-miR-520c-3p	CLIP-seq
MIRT1110122	hsa-miR-520d-3p	CLIP-seq
MIRT1110124	hsa-miR-520e	CLIP-seq
MIRT1110125	hsa-miR-520g	CLIP-seq
MIRT1110126	hsa-miR-520h	CLIP-seq
MIRT1110132	hsa-miR-552	CLIP-seq
MIRT2030673	hsa-miR-605	CLIP-seq
MIRT1110140	hsa-miR-642b	CLIP-seq
MIRT1110143	hsa-miR-661	CLIP-seq
MIRT2030674	hsa-miR-675	CLIP-seq
MIRT1110146	hsa-miR-766	CLIP-seq
MIRT2030675	hsa-miR-767-5p	CLIP-seq
MIRT2030676	hsa-miR-770-5p	CLIP-seq
MIRT1110148	hsa-miR-93	CLIP-seq
MIRT2030677	hsa-miR-936	CLIP-seq
MIRT2030678	hsa-miR-940	CLIP-seq
MIRT1110024	hsa-miR-106a	CLIP-seq
MIRT1110025	hsa-miR-106b	CLIP-seq
MIRT2030644	hsa-miR-122	CLIP-seq
MIRT1110029	hsa-miR-1254	CLIP-seq
MIRT1110030	hsa-miR-1262	CLIP-seq
MIRT1110031	hsa-miR-128	CLIP-seq
MIRT1110038	hsa-miR-17	CLIP-seq
MIRT2261357	hsa-miR-181a	CLIP-seq
MIRT2261358	hsa-miR-181b	CLIP-seq
MIRT2261359	hsa-miR-181c	CLIP-seq
MIRT2261360	hsa-miR-181d	CLIP-seq
MIRT2030646	hsa-miR-1827	CLIP-seq
MIRT2261361	hsa-miR-1908	CLIP-seq
MIRT1110039	hsa-miR-20a	CLIP-seq
MIRT1110040	hsa-miR-20b	CLIP-seq
MIRT1110041	hsa-miR-302a	CLIP-seq
MIRT1110042	hsa-miR-302b	CLIP-seq
MIRT1110043	hsa-miR-302c	CLIP-seq
MIRT1110044	hsa-miR-302d	CLIP-seq
MIRT1110045	hsa-miR-302e	CLIP-seq
MIRT1110051	hsa-miR-3116	CLIP-seq
MIRT2261362	hsa-miR-3117-3p	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT2030647	hsa-miR-3135b	CLIP-seq
MIRT2261363	hsa-miR-3140-5p	CLIP-seq
MIRT2261364	hsa-miR-3159	CLIP-seq
MIRT2261365	hsa-miR-3169	CLIP-seq
MIRT1110058	hsa-miR-3180-5p	CLIP-seq
MIRT2261366	hsa-miR-3194-3p	CLIP-seq
MIRT2030649	hsa-miR-34b	CLIP-seq
MIRT2261367	hsa-miR-3607-3p	CLIP-seq
MIRT1110061	hsa-miR-3614-3p	CLIP-seq
MIRT2030650	hsa-miR-3614-5p	CLIP-seq
MIRT1110063	hsa-miR-3622a-3p	CLIP-seq
MIRT1110064	hsa-miR-3622b-3p	CLIP-seq
MIRT2030652	hsa-miR-3652	CLIP-seq
MIRT2261368	hsa-miR-3656	CLIP-seq
MIRT2030653	hsa-miR-3664-3p	CLIP-seq
MIRT1110070	hsa-miR-3672	CLIP-seq
MIRT2261369	hsa-miR-3686	CLIP-seq
MIRT1110071	hsa-miR-3690	CLIP-seq
MIRT1110073	hsa-miR-372	CLIP-seq
MIRT1110074	hsa-miR-373	CLIP-seq
MIRT1110075	hsa-miR-378g	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT2030655	hsa-miR-3929	CLIP-seq
MIRT1110077	hsa-miR-3934	CLIP-seq
MIRT1110078	hsa-miR-4252	CLIP-seq
MIRT2261370	hsa-miR-4262	CLIP-seq
MIRT1110082	hsa-miR-4274	CLIP-seq
MIRT1110084	hsa-miR-4297	CLIP-seq
MIRT2261371	hsa-miR-431	CLIP-seq
MIRT2030656	hsa-miR-4419b	CLIP-seq
MIRT2261372	hsa-miR-4427	CLIP-seq
MIRT2030657	hsa-miR-4430	CLIP-seq
MIRT1110085	hsa-miR-4433	CLIP-seq
MIRT1110090	hsa-miR-4459	CLIP-seq
MIRT2030658	hsa-miR-4466	CLIP-seq
MIRT2030660	hsa-miR-4478	CLIP-seq
MIRT1110092	hsa-miR-4519	CLIP-seq
MIRT1110093	hsa-miR-4524	CLIP-seq
MIRT2261373	hsa-miR-4537	CLIP-seq
MIRT1110095	hsa-miR-4638-3p	CLIP-seq
MIRT2030661	hsa-miR-4649-3p	CLIP-seq
MIRT2261374	hsa-miR-4653-3p	CLIP-seq
MIRT2030662	hsa-miR-4695-3p	CLIP-seq
MIRT2030663	hsa-miR-4695-5p	CLIP-seq
MIRT1110098	hsa-miR-4701-3p	CLIP-seq
MIRT2261375	hsa-miR-4707-3p	CLIP-seq
MIRT2030665	hsa-miR-4722-5p	CLIP-seq
MIRT1110101	hsa-miR-4731-5p	CLIP-seq
MIRT2261376	hsa-miR-4735-5p	CLIP-seq
MIRT1110102	hsa-miR-4747-5p	CLIP-seq
MIRT2261377	hsa-miR-4759	CLIP-seq
MIRT1110103	hsa-miR-4761-5p	CLIP-seq
MIRT1110106	hsa-miR-4768-3p	CLIP-seq
MIRT2030666	hsa-miR-4772-3p	CLIP-seq
MIRT2261378	hsa-miR-4775	CLIP-seq
MIRT1110107	hsa-miR-4786-3p	CLIP-seq
MIRT1110108	hsa-miR-4793-3p	CLIP-seq
MIRT1110109	hsa-miR-4802-3p	CLIP-seq
MIRT2030667	hsa-miR-485-5p	CLIP-seq
MIRT1110112	hsa-miR-508-5p	CLIP-seq
MIRT1110113	hsa-miR-5095	CLIP-seq
MIRT2030671	hsa-miR-510	CLIP-seq
MIRT1110114	hsa-miR-512-3p	CLIP-seq
MIRT2030672	hsa-miR-512-5p	CLIP-seq
MIRT1110117	hsa-miR-519d	CLIP-seq
MIRT1110118	hsa-miR-520a-3p	CLIP-seq
MIRT1110119	hsa-miR-520a-5p	CLIP-seq
MIRT1110120	hsa-miR-520b	CLIP-seq
MIRT1110121	hsa-miR-520c-3p	CLIP-seq
MIRT1110122	hsa-miR-520d-3p	CLIP-seq
MIRT1110124	hsa-miR-520e	CLIP-seq
MIRT1110125	hsa-miR-520g	CLIP-seq
MIRT1110126	hsa-miR-520h	CLIP-seq
MIRT1110128	hsa-miR-525-5p	CLIP-seq
MIRT1110129	hsa-miR-541	CLIP-seq
MIRT1110130	hsa-miR-544b	CLIP-seq
MIRT2261379	hsa-miR-550a	CLIP-seq
MIRT1110132	hsa-miR-552	CLIP-seq
MIRT2261380	hsa-miR-590-3p	CLIP-seq
MIRT2261381	hsa-miR-615-5p	CLIP-seq
MIRT1110140	hsa-miR-642b	CLIP-seq
MIRT1110141	hsa-miR-654-5p	CLIP-seq
MIRT1110142	hsa-miR-659	CLIP-seq
MIRT1110143	hsa-miR-661	CLIP-seq
MIRT2261382	hsa-miR-663	CLIP-seq
MIRT1110145	hsa-miR-671-5p	CLIP-seq
MIRT2030674	hsa-miR-675	CLIP-seq
MIRT1110146	hsa-miR-766	CLIP-seq
MIRT1110147	hsa-miR-9	CLIP-seq
MIRT2261383	hsa-miR-924	CLIP-seq
MIRT1110148	hsa-miR-93	CLIP-seq
MIRT2030678	hsa-miR-940	CLIP-seq
MIRT2390154	hsa-miR-10a	CLIP-seq
MIRT2390155	hsa-miR-10b	CLIP-seq
MIRT1110029	hsa-miR-1254	CLIP-seq
MIRT1110051	hsa-miR-3116	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT1110058	hsa-miR-3180-5p	CLIP-seq
MIRT1110060	hsa-miR-329	CLIP-seq
MIRT2390156	hsa-miR-3620	CLIP-seq
MIRT1110063	hsa-miR-3622a-3p	CLIP-seq
MIRT1110064	hsa-miR-3622b-3p	CLIP-seq
MIRT1110065	hsa-miR-362-3p	CLIP-seq
MIRT2030654	hsa-miR-3688-5p	CLIP-seq
MIRT1110071	hsa-miR-3690	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT1110085	hsa-miR-4433	CLIP-seq
MIRT1110090	hsa-miR-4459	CLIP-seq
MIRT1110095	hsa-miR-4638-3p	CLIP-seq
MIRT1110102	hsa-miR-4747-5p	CLIP-seq
MIRT1110103	hsa-miR-4761-5p	CLIP-seq
MIRT1110106	hsa-miR-4768-3p	CLIP-seq
MIRT1110107	hsa-miR-4786-3p	CLIP-seq
MIRT1110119	hsa-miR-520a-5p	CLIP-seq
MIRT1110123	hsa-miR-520d-5p	CLIP-seq
MIRT1110127	hsa-miR-524-5p	CLIP-seq
MIRT1110128	hsa-miR-525-5p	CLIP-seq
MIRT1110129	hsa-miR-541	CLIP-seq
MIRT1110141	hsa-miR-654-5p	CLIP-seq
MIRT1110145	hsa-miR-671-5p	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT2453057	hsa-miR-3659	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT2453058	hsa-miR-4658	CLIP-seq
MIRT2453059	hsa-miR-4684-5p	CLIP-seq
MIRT1110102	hsa-miR-4747-5p	CLIP-seq
MIRT1110103	hsa-miR-4761-5p	CLIP-seq
MIRT1110107	hsa-miR-4786-3p	CLIP-seq
MIRT1110129	hsa-miR-541	CLIP-seq
MIRT2453060	hsa-miR-548c-3p	CLIP-seq
MIRT2453061	hsa-miR-574-5p	CLIP-seq
MIRT2453062	hsa-miR-644	CLIP-seq
MIRT1110141	hsa-miR-654-5p	CLIP-seq
MIRT1110145	hsa-miR-671-5p	CLIP-seq
MIRT2030644	hsa-miR-122	CLIP-seq
MIRT2561379	hsa-miR-1237	CLIP-seq
MIRT2561380	hsa-miR-1248	CLIP-seq
MIRT2561381	hsa-miR-129-5p	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT2030647	hsa-miR-3135b	CLIP-seq
MIRT2561382	hsa-miR-3149	CLIP-seq
MIRT2030651	hsa-miR-3615	CLIP-seq
MIRT1110063	hsa-miR-3622a-3p	CLIP-seq
MIRT1110064	hsa-miR-3622b-3p	CLIP-seq
MIRT2561383	hsa-miR-3622b-5p	CLIP-seq
MIRT2561384	hsa-miR-362-5p	CLIP-seq
MIRT2030652	hsa-miR-3652	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT2561385	hsa-miR-411	CLIP-seq
MIRT2030657	hsa-miR-4430	CLIP-seq
MIRT2030658	hsa-miR-4466	CLIP-seq
MIRT2030662	hsa-miR-4695-3p	CLIP-seq
MIRT2261376	hsa-miR-4735-5p	CLIP-seq
MIRT1110102	hsa-miR-4747-5p	CLIP-seq
MIRT1110103	hsa-miR-4761-5p	CLIP-seq
MIRT2030666	hsa-miR-4772-3p	CLIP-seq
MIRT2261378	hsa-miR-4775	CLIP-seq
MIRT1110107	hsa-miR-4786-3p	CLIP-seq
MIRT2561386	hsa-miR-4795-3p	CLIP-seq
MIRT2030668	hsa-miR-498	CLIP-seq
MIRT2561387	hsa-miR-500b	CLIP-seq
MIRT2561388	hsa-miR-501-5p	CLIP-seq
MIRT1110129	hsa-miR-541	CLIP-seq
MIRT2261380	hsa-miR-590-3p	CLIP-seq
MIRT1110141	hsa-miR-654-5p	CLIP-seq
MIRT1110145	hsa-miR-671-5p	CLIP-seq
MIRT2030674	hsa-miR-675	CLIP-seq
MIRT2561389	hsa-miR-941	CLIP-seq
MIRT2561390	hsa-miR-944	CLIP-seq
MIRT2030644	hsa-miR-122	CLIP-seq
MIRT2561379	hsa-miR-1237	CLIP-seq
MIRT2561380	hsa-miR-1248	CLIP-seq
MIRT2561381	hsa-miR-129-5p	CLIP-seq
MIRT1110052	hsa-miR-3122	CLIP-seq
MIRT2030647	hsa-miR-3135b	CLIP-seq
MIRT2561382	hsa-miR-3149	CLIP-seq
MIRT2030651	hsa-miR-3615	CLIP-seq
MIRT2561383	hsa-miR-3622b-5p	CLIP-seq
MIRT2561384	hsa-miR-362-5p	CLIP-seq
MIRT2030652	hsa-miR-3652	CLIP-seq
MIRT1110076	hsa-miR-3913-5p	CLIP-seq
MIRT2030657	hsa-miR-4430	CLIP-seq
MIRT1110085	hsa-miR-4433	CLIP-seq
MIRT1110090	hsa-miR-4459	CLIP-seq
MIRT2030658	hsa-miR-4466	CLIP-seq
MIRT2030662	hsa-miR-4695-3p	CLIP-seq
MIRT2261376	hsa-miR-4735-5p	CLIP-seq
MIRT1110102	hsa-miR-4747-5p	CLIP-seq
MIRT1110103	hsa-miR-4761-5p	CLIP-seq
MIRT1110106	hsa-miR-4768-3p	CLIP-seq
MIRT2030666	hsa-miR-4772-3p	CLIP-seq
MIRT2261378	hsa-miR-4775	CLIP-seq
MIRT1110107	hsa-miR-4786-3p	CLIP-seq
MIRT2561386	hsa-miR-4795-3p	CLIP-seq
MIRT2561387	hsa-miR-500b	CLIP-seq
MIRT2561388	hsa-miR-501-5p	CLIP-seq
MIRT1110129	hsa-miR-541	CLIP-seq
MIRT2261380	hsa-miR-590-3p	CLIP-seq
MIRT1110141	hsa-miR-654-5p	CLIP-seq
MIRT1110145	hsa-miR-671-5p	CLIP-seq
MIRT2030674	hsa-miR-675	CLIP-seq
MIRT2561389	hsa-miR-941	CLIP-seq
MIRT2561390	hsa-miR-944	CLIP-seq

Transcription factors

Show/Hide all(3)

Transcription factor	Regulation	Reference
KAT2B	Unknown	24631505
REST	Repression	22532168
SIRT1	Unknown	24631505

Show/Hide all(35)

GO ID	Ontology	Definition	Evidence	Reference
GO:0000932	Component	P-body	IDA	17617744
GO:0002151	Function	G-quadruplex RNA binding	ISS
GO:0003723	Function	RNA binding	IDA	18951094, 19703396
GO:0005515	Function	Protein binding	IPI	19703396, 21247876, 32296183, 32814053
GO:0005634	Component	Nucleus	IDA	17617744
GO:0005730	Component	Nucleolus	IDA
GO:0005737	Component	Cytoplasm	IDA	18604195, 20014101
GO:0005791	Component	Rough endoplasmic reticulum	ISS
GO:0005829	Component	Cytosol	IDA
GO:0005829	Component	Cytosol	TAS
GO:0005844	Component	Polysome	IDA	21247876
GO:0007281	Process	Germ cell development	IEA
GO:0008270	Function	Zinc ion binding	IEA
GO:0010494	Component	Cytoplasmic stress granule	IDA	17617744
GO:0010587	Process	MiRNA catabolic process	IMP	18951094, 19703396
GO:0017148	Process	Negative regulation of translation	ISS
GO:0019827	Process	Stem cell population maintenance	IMP	19703396
GO:0031054	Process	Pre-miRNA processing	IMP	18951094, 19703396
GO:0031123	Process	RNA 3'-end processing	IMP	18951094, 19703396
GO:0031369	Function	Translation initiation factor binding	IEA
GO:0032008	Process	Positive regulation of TOR signaling	ISS
GO:0035019	Process	Somatic stem cell population maintenance	TAS
GO:0035198	Function	MiRNA binding	ISS
GO:0045666	Process	Positive regulation of neuron differentiation	IEA
GO:0045686	Process	Negative regulation of glial cell differentiation	IEA
GO:0048863	Process	Stem cell differentiation	IEA
GO:0051897	Process	Positive regulation of protein kinase B signaling	ISS
GO:0071076	Process	RNA 3' uridylation	IEA
GO:0071333	Process	Cellular response to glucose stimulus	ISS
GO:1901724	Process	Positive regulation of cell proliferation involved in kidney development	IEA
GO:1903800	Process	Positive regulation of production of miRNAs involved in gene silencing by miRNA	ISS
GO:1905538	Function	Polysome binding	IDA	21247876
GO:1990825	Function	Sequence-specific mRNA binding	ISS
GO:1990904	Component	Ribonucleoprotein complex	IDA	21247876
GO:2000767	Process	Positive regulation of cytoplasmic translation	IMP	21247876

MIM	HGNC	e!Ensembl
611043	15986	ENSG00000131914

Protein

UniProt ID

Q9H9Z2

Protein name

Protein lin-28 homolog A (Lin-28A) (Zinc finger CCHC domain-containing protein 1)

Protein function

RNA-binding protein that inhibits processing of pre-let-7 miRNAs and regulates translation of mRNAs that control developmental timing, pluripotency and metabolism (PubMed:21247876). Seems to recognize a common structural G-quartet (G4) feature i

PDB

2CQF , 2LI8 , 5UDZ , 8OPS , 8OPT , 8OST

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00313	CSD	40 → 112		Domain
PF00098	zf-CCHC	137 → 154	Zinc knuckle	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed in embryonic stem cells, placenta and testis. Tends to be up-regulated in HER2-overexpressing breast tumors. {ECO:0000269|PubMed:14688391, ECO:0000269|PubMed:15614775, ECO:0000269|PubMed:15722555, ECO:0000269|PubMed:22118463}

Sequence

MGSVSNQQFAGGCAKAAEEAPEEAPEDAARAADEPQLLHGAGICKWFNVRMGFGFLSMTA
RAGVALDPPVDVFVHQSKLHMEGFRSLKEGEAVEFTFKKSAKGLESIRVTGPGGVFCIGS
ERRPKGKSMQKRRSKGDRCYNCGGLDHHAKECKLPPQPKKCHFCQSISHMVASCPLKAQQ
GPSAQGKPTYFREEEEEIHSPTLLPEAQN

Sequence length

209

Interactions

View interactions

	Reactome
			Transcriptional regulation of pluripotent stem cells

Show/Hide Unknown Diseases (1)

Disease term	Disease name	Evidence	References	Source
Unknown
Metabolic Syndrome	Metabolic Syndrome			GWAS

Show/Hide Text Mining Associations (68)

Disease Name	Relationship Type	References
Associations from Text Mining
Ameloblastoma	Associate	37559082
Atherosclerosis	Associate	27230676
Brain Neoplasms	Associate	22691720, 31287992
Breast Neoplasms	Associate	21912531, 22118463, 22808086, 23840685, 24349438, 26149387, 26460550, 28102845, 32560271, 39849871
Carcinogenesis	Associate	23161096, 25503985, 29724816, 29874593, 30531691
Carcinogenesis	Inhibit	26080928
Carcinoma	Stimulate	22467868
Carcinoma Hepatocellular	Associate	22429493, 24475120, 29742265, 33901943, 35955552
Carcinoma Lobular	Associate	39849871
Carcinoma Non Small Cell Lung	Associate	24780874, 28235063
Carcinoma Ovarian Epithelial	Associate	23255092, 26158423, 30365085
Carcinoma Renal Cell	Associate	21982273
Carcinoma Small Cell	Associate	34911496
Central Nervous System Infections	Associate	22691720
Choroideremia	Associate	36395688
Colonic Neoplasms	Associate	24475120
Colorectal Neoplasms	Associate	26687759, 27793004, 27859935, 29393430, 31510013
Crigler Najjar Syndrome	Associate	33485181
Cryptorchidism	Associate	31274480
Death	Associate	30833806
Diabetes Mellitus Type 2	Associate	37028179
Endometrial Neoplasms	Associate	35832124
Erdheim Chester Disease	Associate	34785791
Esophageal Squamous Cell Carcinoma	Associate	29393461
Fetal Growth Retardation	Associate	31415216
Glioblastoma	Associate	24475120
Glioma	Associate	24475120
Glycogen Storage Disease IIIA	Associate	30269021
Heart Diseases	Associate	30734494
Hepatitis B Chronic	Associate	32571380
Hereditary Breast and Ovarian Cancer Syndrome	Associate	22118463, 23840685
Hypoxia	Associate	32560271
Inflammation	Associate	24499937, 24780874
Leukemia	Associate	29874593
Leukemia Myeloid	Associate	28569789
Leukemia Myeloid Acute	Associate	28569789
Lymphatic Metastasis	Stimulate	22433967
Lymphatic Metastasis	Associate	30531691
Machado Joseph Disease	Associate	27346190, 27346191
Medulloblastoma	Associate	26250335
Mood Disorders	Associate	31235756
Mouth Neoplasms	Associate	25503985
Myopathy with Giant Abnormal Mitochondria	Associate	27230676
Neoplasm Metastasis	Associate	22691720, 24349438, 25503985, 29393461, 30543854, 31510013, 35102250
Neoplasms	Associate	22118463, 22162396, 22210895, 22429493, 22433967, 22808086, 23255092, 23774216, 24337497, 24349438, 24475120, 24558755, 25301052, 25378324, 26080928 View all (24 more)
Neoplasms	Stimulate	22467868, 31379107
Neoplasms	Inhibit	25190313, 36524732
Neoplasms Germ Cell and Embryonal	Associate	22296229, 23161096, 23774216, 24475120, 31287992
Neuroblastoma	Associate	31747721
Neuroectodermal Tumors Primitive	Associate	22691720, 24839957, 27074032
Non Muscle Invasive Bladder Neoplasms	Associate	32623385
Ovarian Neoplasms	Associate	23255092, 24475120, 26583126, 30365085
Pancreatic Neoplasms	Associate	26910839
Parkinson Disease	Associate	38615589
Prostatic Neoplasms	Associate	26714839
Prostatic Neoplasms Castration Resistant	Associate	28910332
Radiation Injuries	Associate	23840685
Radiation Pneumonitis	Associate	24780874
Retrograde Degeneration	Associate	30789962
Rett Syndrome	Associate	30789962
Rhabdoid Tumor Predisposition Syndrome 1	Associate	23161096
Stomach Neoplasms	Associate	25128063, 26893371, 29510730, 30833806, 36160641
Teratoma	Associate	33799273
Thyroid Cancer Papillary	Associate	30531691
Tongue Neoplasms	Associate	27464948
Triple Negative Breast Neoplasms	Associate	35102250
Urinary Bladder Neoplasms	Associate	33516780
Wilms Tumor	Associate	25190313, 31338973

LIN28A (lin-28 RNA binding posttranscriptional regulator A)