Gene
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.
7813
Gene name Gene Name - the full gene name approved by the HGNC.
Ecotropic viral integration site 5
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.
EVI5
Synonyms (NCBI Gene) Gene synonyms aliases
EVI-5, NB4S
Chromosome Chromosome number
1
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
1p22.1
miRNA miRNA information provided by mirtarbase database.
miRTarBase ID miRNA Experiments Reference
MIRT022914 hsa-miR-124-3p Microarray 18668037
MIRT027925 hsa-miR-96-5p Sequencing 20371350
MIRT047210 hsa-miR-182-5p CLASH 23622248
MIRT523844 hsa-miR-493-5p HITS-CLIP 21572407
MIRT523841 hsa-miR-5580-3p HITS-CLIP 21572407
Gene ontology (GO) Gene ontology information of associated ontologies with gene provided by GO database.
GO ID Ontology Definition Evidence Reference
GO:0005096 Function GTPase activator activity IBA 21873635
GO:0005096 Function GTPase activator activity IDA 17562788
GO:0005515 Function Protein binding IPI 16439210, 17229837, 26496610, 30126976, 32296183
GO:0005634 Component Nucleus IEA
GO:0005815 Component Microtubule organizing center IEA
Other IDs Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
MIM HGNC e!Ensembl
602942 3501 ENSG00000067208
Protein
UniProt ID O60447
Protein name Ecotropic viral integration site 5 protein homolog (EVI-5) (Neuroblastoma stage 4S gene protein)
Protein function Functions as a regulator of cell cycle progression by stabilizing the FBXO5 protein and promoting cyclin-A accumulation during interphase. May play a role in cytokinesis.
Family and domains

Pfam

Accession ID Position in sequence Description Type
PF00566 RabGAP-TBC 166 368 Rab-GTPase-TBC domain Family
Tissue specificity TISSUE SPECIFICITY: Expressed in various cell lines (at protein level). Expressed in a wide range of tissues including brain and adrenal. {ECO:0000269|PubMed:16033705, ECO:0000269|PubMed:9618176}.
Sequence
MVTNKMTAAFRNPSGKQVATDKVAEKLSSTLSWVKNTVSHTVSQMASQVASPSTSLHTTS
SSTTLSTPALSPSSPSQLSPDDLELLAKLEEQNRLLETDSKSLRSVNGSRRNSGSSLVSS
SSASSNLSHLEEDSWILWGRIVNEWEDVRKKKEKQVKELVHKGIPHHFRAIVWQLLCSAQ
SMPIKDQYSELLKMTSPCEKLIRRDIARTYPEHNFFKEKDSLGQEVLFNVMKAYSLVDRE
VGYCQGSAFIVGLLLMQMPEEEAFCVFVKLMQDYRLRELFKPSMAELGLCMYQFECMIQE
HLPELFVHFQSQSFHTSMYASSWFLTIFLTTFPLPIATRIFDIFMSEGLEIVFRVGLALL
QMNQAELM
QLDMEGMLQHFQKVIPHQFDGVPDKLIQAAYQVKYNSKKMKKLEKEYTTIKT
KEMEEQVEIKRLRTENRLLKQRIETLEKHKCSSNYNEDFVLQLEKELVQARLSEAESQCA
LKEMQDKVLDIEKRNNSLPDENNIARLQEELIAVKLREAEAIMGLKELRQQVKDLEEHWQ
RHLARTTGRWKDPPKKNAMNELQDELMTIRLREAETQAEIREIKQRMMEMETQNQINSNH
LRRAEQEVISLQEKVQYLSAQNKGLLTQLSEAKRKQAEIECKNKEEVMAVRLREADSIAA
VAELRQHIAELEIQKEEGKLQGQLNKSDSNQYIGELKDQIAELNHELRCLKGQRGFSGQP
PFDGIHIVNHLIGDDESFHSSDEDFIDNSLQETGVGFPLHGKSGSMSLDPAVADGSESET
EDSVLETRESNQVVQKERPPRRRESYSTTV
Sequence length 810
Interactions View interactions
Associated diseases Disease information provided by ClinVar, GenCC, and GWAS databases.
Causal
Disease term Disease name dbSNP ID References
Multiple sclerosis Multiple Sclerosis rs104895219, rs483353022, rs483353023, rs483353028, rs483353029, rs483353024, rs483353030, rs3207617, rs483353031, rs483353032, rs483353033, rs483353034, rs483353035, rs483353036, rs483353039
View all (4 more)
21833088, 26819262, 24076602
Unknown
Disease term Disease name Evidence References Source
Asthma Asthma 29785011 ClinVar
Eczema Eczema GWAS
Multiple Sclerosis Multiple Sclerosis GWAS
Metabolic Syndrome Metabolic Syndrome GWAS
Associations from Text Mining
Disease Name Relationship Type References
Carcinoma Hepatocellular Associate 25537516
Chromosome Deletion Inhibit 27909306
Multiple Myeloma Associate 27909306
Multiple Sclerosis Associate 19865102, 20087403, 24130709, 26433934, 32355262
Neoplasm Metastasis Associate 25537516
Neoplasms Associate 25537516