Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	7570
Gene name Gene Name - the full gene name approved by the HGNC.	Zinc finger protein 22
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	ZNF22
Synonyms (NCBI Gene) Gene synonyms aliases	HKR-T1, KOX15, ZNF422, Zfp422
Chromosome Chromosome number	10
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	10q11.21

Show/Hide all(243)

miRTarBase ID	miRNA	Experiments	Reference
MIRT648393	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT648394	hsa-miR-4469	HITS-CLIP	23824327
MIRT648392	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT648391	hsa-miR-4287	HITS-CLIP	23824327
MIRT648390	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT648389	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT648388	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT648387	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT648386	hsa-miR-4713-5p	HITS-CLIP	23824327
MIRT648385	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT648384	hsa-miR-629-3p	HITS-CLIP	23824327
MIRT648383	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT648382	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT648381	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT648393	hsa-miR-6832-3p	HITS-CLIP	23824327
MIRT648394	hsa-miR-4469	HITS-CLIP	23824327
MIRT648392	hsa-miR-7113-3p	HITS-CLIP	23824327
MIRT648391	hsa-miR-4287	HITS-CLIP	23824327
MIRT648390	hsa-miR-4685-3p	HITS-CLIP	23824327
MIRT648389	hsa-miR-942-5p	HITS-CLIP	23824327
MIRT648388	hsa-miR-204-5p	HITS-CLIP	23824327
MIRT648387	hsa-miR-211-5p	HITS-CLIP	23824327
MIRT648386	hsa-miR-4713-5p	HITS-CLIP	23824327
MIRT648385	hsa-miR-6867-3p	HITS-CLIP	23824327
MIRT648384	hsa-miR-629-3p	HITS-CLIP	23824327
MIRT648383	hsa-miR-6875-3p	HITS-CLIP	23824327
MIRT648382	hsa-miR-4659a-3p	HITS-CLIP	23824327
MIRT648381	hsa-miR-4659b-3p	HITS-CLIP	23824327
MIRT1518510	hsa-miR-1245	CLIP-seq
MIRT1518511	hsa-miR-1267	CLIP-seq
MIRT1518512	hsa-miR-142-5p	CLIP-seq
MIRT1518513	hsa-miR-216a	CLIP-seq
MIRT1518514	hsa-miR-298	CLIP-seq
MIRT1518515	hsa-miR-3185	CLIP-seq
MIRT1518516	hsa-miR-340	CLIP-seq
MIRT1518517	hsa-miR-3647-3p	CLIP-seq
MIRT1518518	hsa-miR-3678-3p	CLIP-seq
MIRT1518519	hsa-miR-3681	CLIP-seq
MIRT1518520	hsa-miR-4422	CLIP-seq
MIRT1518521	hsa-miR-4684-3p	CLIP-seq
MIRT1518522	hsa-miR-4694-3p	CLIP-seq
MIRT1518523	hsa-miR-490-5p	CLIP-seq
MIRT1518524	hsa-miR-494	CLIP-seq
MIRT1518525	hsa-miR-520d-5p	CLIP-seq
MIRT1518526	hsa-miR-524-5p	CLIP-seq
MIRT1518527	hsa-miR-548n	CLIP-seq
MIRT1518528	hsa-miR-942	CLIP-seq
MIRT2156467	hsa-miR-1271	CLIP-seq
MIRT2156468	hsa-miR-204	CLIP-seq
MIRT2156469	hsa-miR-211	CLIP-seq
MIRT2156470	hsa-miR-3117-5p	CLIP-seq
MIRT2156471	hsa-miR-3120-3p	CLIP-seq
MIRT1518515	hsa-miR-3185	CLIP-seq
MIRT2156472	hsa-miR-323-3p	CLIP-seq
MIRT2156473	hsa-miR-3614-5p	CLIP-seq
MIRT2156474	hsa-miR-374c	CLIP-seq
MIRT2156475	hsa-miR-4277	CLIP-seq
MIRT2156476	hsa-miR-4431	CLIP-seq
MIRT2156477	hsa-miR-4503	CLIP-seq
MIRT2156478	hsa-miR-4719	CLIP-seq
MIRT1518523	hsa-miR-490-5p	CLIP-seq
MIRT2156479	hsa-miR-548c-3p	CLIP-seq
MIRT2156480	hsa-miR-616	CLIP-seq
MIRT2156481	hsa-miR-642b	CLIP-seq
MIRT2156482	hsa-miR-653	CLIP-seq
MIRT2156483	hsa-miR-655	CLIP-seq
MIRT2156484	hsa-miR-767-5p	CLIP-seq
MIRT2156485	hsa-miR-922	CLIP-seq
MIRT1518528	hsa-miR-942	CLIP-seq
MIRT2156486	hsa-miR-96	CLIP-seq
MIRT2156467	hsa-miR-1271	CLIP-seq
MIRT2376008	hsa-miR-128	CLIP-seq
MIRT2156468	hsa-miR-204	CLIP-seq
MIRT2156469	hsa-miR-211	CLIP-seq
MIRT2376009	hsa-miR-2113	CLIP-seq
MIRT2376010	hsa-miR-218	CLIP-seq
MIRT2376011	hsa-miR-27a	CLIP-seq
MIRT2376012	hsa-miR-27b	CLIP-seq
MIRT2156470	hsa-miR-3117-5p	CLIP-seq
MIRT1518515	hsa-miR-3185	CLIP-seq
MIRT2156472	hsa-miR-323-3p	CLIP-seq
MIRT2156473	hsa-miR-3614-5p	CLIP-seq
MIRT2376013	hsa-miR-3622b-5p	CLIP-seq
MIRT2376014	hsa-miR-3692	CLIP-seq
MIRT2376015	hsa-miR-4253	CLIP-seq
MIRT2156476	hsa-miR-4431	CLIP-seq
MIRT2156477	hsa-miR-4503	CLIP-seq
MIRT2376016	hsa-miR-4716-5p	CLIP-seq
MIRT2376017	hsa-miR-4761-3p	CLIP-seq
MIRT1518523	hsa-miR-490-5p	CLIP-seq
MIRT2156480	hsa-miR-616	CLIP-seq
MIRT2156481	hsa-miR-642b	CLIP-seq
MIRT2156482	hsa-miR-653	CLIP-seq
MIRT2156484	hsa-miR-767-5p	CLIP-seq
MIRT1518528	hsa-miR-942	CLIP-seq
MIRT2156486	hsa-miR-96	CLIP-seq
MIRT2156467	hsa-miR-1271	CLIP-seq
MIRT2156468	hsa-miR-204	CLIP-seq
MIRT2156469	hsa-miR-211	CLIP-seq
MIRT2156470	hsa-miR-3117-5p	CLIP-seq
MIRT1518515	hsa-miR-3185	CLIP-seq
MIRT2156472	hsa-miR-323-3p	CLIP-seq
MIRT2156473	hsa-miR-3614-5p	CLIP-seq
MIRT2156476	hsa-miR-4431	CLIP-seq
MIRT2156477	hsa-miR-4503	CLIP-seq
MIRT1518523	hsa-miR-490-5p	CLIP-seq
MIRT1518524	hsa-miR-494	CLIP-seq
MIRT2156481	hsa-miR-642b	CLIP-seq
MIRT2156482	hsa-miR-653	CLIP-seq
MIRT2156484	hsa-miR-767-5p	CLIP-seq
MIRT1518528	hsa-miR-942	CLIP-seq
MIRT2156486	hsa-miR-96	CLIP-seq
MIRT2156468	hsa-miR-204	CLIP-seq
MIRT2156469	hsa-miR-211	CLIP-seq
MIRT1518528	hsa-miR-942	CLIP-seq
MIRT2441814	hsa-miR-4464	CLIP-seq
MIRT2156477	hsa-miR-4503	CLIP-seq
MIRT2441815	hsa-miR-4748	CLIP-seq
MIRT2156468	hsa-miR-204	CLIP-seq
MIRT2156469	hsa-miR-211	CLIP-seq
MIRT1518528	hsa-miR-942	CLIP-seq
MIRT2464101	hsa-miR-1253	CLIP-seq
MIRT2464102	hsa-miR-4428	CLIP-seq
MIRT2464103	hsa-miR-4434	CLIP-seq
MIRT2464104	hsa-miR-4516	CLIP-seq
MIRT2464105	hsa-miR-549	CLIP-seq
MIRT2464101	hsa-miR-1253	CLIP-seq
MIRT2464102	hsa-miR-4428	CLIP-seq
MIRT2464103	hsa-miR-4434	CLIP-seq
MIRT2464104	hsa-miR-4516	CLIP-seq
MIRT2464105	hsa-miR-549	CLIP-seq
MIRT2668454	hsa-miR-1207-5p	CLIP-seq
MIRT2156467	hsa-miR-1271	CLIP-seq
MIRT2376008	hsa-miR-128	CLIP-seq
MIRT2668455	hsa-miR-1321	CLIP-seq
MIRT2668456	hsa-miR-1323	CLIP-seq
MIRT2668457	hsa-miR-194	CLIP-seq
MIRT2376011	hsa-miR-27a	CLIP-seq
MIRT2376012	hsa-miR-27b	CLIP-seq
MIRT2668458	hsa-miR-28-5p	CLIP-seq
MIRT2156470	hsa-miR-3117-5p	CLIP-seq
MIRT2668459	hsa-miR-3139	CLIP-seq
MIRT1518515	hsa-miR-3185	CLIP-seq
MIRT2156472	hsa-miR-323-3p	CLIP-seq
MIRT2156473	hsa-miR-3614-5p	CLIP-seq
MIRT2668460	hsa-miR-3650	CLIP-seq
MIRT2668461	hsa-miR-3689d	CLIP-seq
MIRT2668462	hsa-miR-3713	CLIP-seq
MIRT2668463	hsa-miR-3714	CLIP-seq
MIRT2668464	hsa-miR-371-5p	CLIP-seq
MIRT2668465	hsa-miR-371b-5p	CLIP-seq
MIRT2668466	hsa-miR-378	CLIP-seq
MIRT2668467	hsa-miR-378b	CLIP-seq
MIRT2668468	hsa-miR-378c	CLIP-seq
MIRT2668469	hsa-miR-378d	CLIP-seq
MIRT2668470	hsa-miR-378e	CLIP-seq
MIRT2668471	hsa-miR-378f	CLIP-seq
MIRT2668472	hsa-miR-378h	CLIP-seq
MIRT2668473	hsa-miR-378i	CLIP-seq
MIRT2668474	hsa-miR-380	CLIP-seq
MIRT2668475	hsa-miR-422a	CLIP-seq
MIRT2668476	hsa-miR-4270	CLIP-seq
MIRT2668477	hsa-miR-4424	CLIP-seq
MIRT2156476	hsa-miR-4431	CLIP-seq
MIRT2668478	hsa-miR-4441	CLIP-seq
MIRT2441814	hsa-miR-4464	CLIP-seq
MIRT2668479	hsa-miR-4493	CLIP-seq
MIRT2156477	hsa-miR-4503	CLIP-seq
MIRT2668480	hsa-miR-4633-3p	CLIP-seq
MIRT2668481	hsa-miR-4635	CLIP-seq
MIRT2156478	hsa-miR-4719	CLIP-seq
MIRT2668482	hsa-miR-4739	CLIP-seq
MIRT2441815	hsa-miR-4748	CLIP-seq
MIRT2668483	hsa-miR-4756-5p	CLIP-seq
MIRT2668484	hsa-miR-4760-3p	CLIP-seq
MIRT2668485	hsa-miR-4763-3p	CLIP-seq
MIRT1518523	hsa-miR-490-5p	CLIP-seq
MIRT1518524	hsa-miR-494	CLIP-seq
MIRT2668486	hsa-miR-513a-3p	CLIP-seq
MIRT2668487	hsa-miR-513b	CLIP-seq
MIRT2668488	hsa-miR-513c	CLIP-seq
MIRT2668489	hsa-miR-514b-5p	CLIP-seq
MIRT2668490	hsa-miR-548o	CLIP-seq
MIRT2668491	hsa-miR-578	CLIP-seq
MIRT2668492	hsa-miR-607	CLIP-seq
MIRT2156481	hsa-miR-642b	CLIP-seq
MIRT2156482	hsa-miR-653	CLIP-seq
MIRT2668493	hsa-miR-664	CLIP-seq
MIRT2668494	hsa-miR-708	CLIP-seq
MIRT2156484	hsa-miR-767-5p	CLIP-seq
MIRT2668495	hsa-miR-940	CLIP-seq
MIRT2156486	hsa-miR-96	CLIP-seq
MIRT2668454	hsa-miR-1207-5p	CLIP-seq
MIRT2156467	hsa-miR-1271	CLIP-seq
MIRT2376008	hsa-miR-128	CLIP-seq
MIRT2668455	hsa-miR-1321	CLIP-seq
MIRT2668456	hsa-miR-1323	CLIP-seq
MIRT2668457	hsa-miR-194	CLIP-seq
MIRT2376011	hsa-miR-27a	CLIP-seq
MIRT2376012	hsa-miR-27b	CLIP-seq
MIRT2156470	hsa-miR-3117-5p	CLIP-seq
MIRT1518515	hsa-miR-3185	CLIP-seq
MIRT2156472	hsa-miR-323-3p	CLIP-seq
MIRT2156473	hsa-miR-3614-5p	CLIP-seq
MIRT2668460	hsa-miR-3650	CLIP-seq
MIRT2668461	hsa-miR-3689d	CLIP-seq
MIRT2668462	hsa-miR-3713	CLIP-seq
MIRT2668463	hsa-miR-3714	CLIP-seq
MIRT2668465	hsa-miR-371b-5p	CLIP-seq
MIRT2668466	hsa-miR-378	CLIP-seq
MIRT2668467	hsa-miR-378b	CLIP-seq
MIRT2668468	hsa-miR-378c	CLIP-seq
MIRT2668469	hsa-miR-378d	CLIP-seq
MIRT2668470	hsa-miR-378e	CLIP-seq
MIRT2668471	hsa-miR-378f	CLIP-seq
MIRT2668472	hsa-miR-378h	CLIP-seq
MIRT2668473	hsa-miR-378i	CLIP-seq
MIRT2668474	hsa-miR-380	CLIP-seq
MIRT2668475	hsa-miR-422a	CLIP-seq
MIRT2668476	hsa-miR-4270	CLIP-seq
MIRT2668477	hsa-miR-4424	CLIP-seq
MIRT2156476	hsa-miR-4431	CLIP-seq
MIRT2668478	hsa-miR-4441	CLIP-seq
MIRT2441814	hsa-miR-4464	CLIP-seq
MIRT2668479	hsa-miR-4493	CLIP-seq
MIRT2156477	hsa-miR-4503	CLIP-seq
MIRT2668481	hsa-miR-4635	CLIP-seq
MIRT2156478	hsa-miR-4719	CLIP-seq
MIRT2668482	hsa-miR-4739	CLIP-seq
MIRT2441815	hsa-miR-4748	CLIP-seq
MIRT2668483	hsa-miR-4756-5p	CLIP-seq
MIRT2668484	hsa-miR-4760-3p	CLIP-seq
MIRT2668485	hsa-miR-4763-3p	CLIP-seq
MIRT1518523	hsa-miR-490-5p	CLIP-seq
MIRT1518524	hsa-miR-494	CLIP-seq
MIRT2668487	hsa-miR-513b	CLIP-seq
MIRT2668490	hsa-miR-548o	CLIP-seq
MIRT2668491	hsa-miR-578	CLIP-seq
MIRT2156481	hsa-miR-642b	CLIP-seq
MIRT2156482	hsa-miR-653	CLIP-seq
MIRT2156484	hsa-miR-767-5p	CLIP-seq
MIRT2668495	hsa-miR-940	CLIP-seq
MIRT2156486	hsa-miR-96	CLIP-seq

Show/Hide all(14)

GO ID	Ontology	Definition	Evidence	Reference
GO:0003677	Function	DNA binding	IEA
GO:0003677	Function	DNA binding	ISS
GO:0003700	Function	DNA-binding transcription factor activity	NAS	34673265
GO:0005515	Function	Protein binding	IPI	35156780
GO:0005634	Component	Nucleus	IBA
GO:0005634	Component	Nucleus	IEA
GO:0005634	Component	Nucleus	ISS
GO:0005654	Component	Nucleoplasm	IDA
GO:0006355	Process	Regulation of DNA-templated transcription	NAS	14630903
GO:0008270	Function	Zinc ion binding	IEA
GO:0008270	Function	Zinc ion binding	TAS	1946370
GO:0010468	Process	Regulation of gene expression	IBA
GO:0042476	Process	Odontogenesis	NAS	14630903
GO:0046872	Function	Metal ion binding	IEA

MIM	HGNC	e!Ensembl
194529	13012	ENSG00000165512

Protein

UniProt ID

P17026

Protein name

Zinc finger protein 22 (Zinc finger protein KOX15) (Zinc finger protein Krox-26)

Protein function

Binds DNA through the consensus sequence 5'-CAATG-3'. May be involved in transcriptional regulation and may play a role in tooth formation (By similarity).

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00096	zf-C2H2	55 → 77	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	83 → 105	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	111 → 133	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	139 → 161	Zinc finger, C2H2 type	Domain
PF00096	zf-C2H2	167 → 189	Zinc finger, C2H2 type	Domain

Tissue specificity

TISSUE SPECIFICITY: In the embryo, expressed in developing craniofacial structures including dental epithelium of maxillary molar tooth organs, tongue epithelium and muscle, and craniofacial bone osteoblasts. In the adult, expressed in mesoderm-derived ti

Sequence

MRLAKPKAGISRSSSQGKAYENKRKTGRQRQKWGMTIRFDSSFSRLRRSLDDKPYKCTEC
EKSFSQSSTLFQHQKIHTGKKSHKCADCGKSFFQSSNLIQHRRIHTGEKPYKCDECGESF
KQSSNLIQHQRIHTGEKPYQCDECGRCFSQSSHLIQHQRTHTGEKPYQCSECGKCFSQSS
HLRQHMKVHKEEKPRKTRGKNIRVKTHLPSWKAGTGRKSVAGLR

Sequence length

224

Interactions

View interactions

Show/Hide Unknown Diseases (1)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Oligodendroglioma	Oligodendroglioma	N/A	N/A	GWAS

Show/Hide Text Mining Associations (3)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Melanoma	Associate	21606880
Neoplasms	Associate	21606880
Precursor T Cell Lymphoblastic Leukemia Lymphoma	Associate	16029452

ZNF22 (zinc finger protein 22)