Gene Details | GeDiPNet - Complete Gene Info, Disease Associations & Pathways

Gene Gene miRNA Gene ontology Other IDs Protein Pathways Associated diseases
Entrez ID Entrez Gene ID - the GENE ID in NCBI Gene database.	7533
Gene name Gene Name - the full gene name approved by the HGNC.	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta
Gene symbol Gene Symbol - the official gene symbol approved by the HGNC.	YWHAH
Synonyms (NCBI Gene) Gene synonyms aliases	YWHA1
Chromosome Chromosome number	22
Chromosome location Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.	22q12.3
Summary Summary of gene provided in NCBI Entrez Gene.	This gene product belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 99% identical to th

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miRTarBase ID	miRNA	Experiments	Reference
MIRT021116	hsa-miR-186-5p	Sequencing	20371350
MIRT027235	hsa-miR-103a-3p	Sequencing	20371350
MIRT028247	hsa-miR-33a-5p	Sequencing	20371350
MIRT028327	hsa-miR-32-5p	Sequencing	20371350
MIRT032075	hsa-miR-16-5p	Sequencing	20371350
MIRT032075	hsa-miR-16-5p	Proteomics	18668040
MIRT021116	hsa-miR-186-5p	CLASH	23622248
MIRT043064	hsa-miR-324-5p	CLASH	23622248
MIRT713127	hsa-miR-34b-3p	HITS-CLIP	19536157
MIRT713126	hsa-miR-6865-3p	HITS-CLIP	19536157
MIRT713125	hsa-miR-3620-3p	HITS-CLIP	19536157
MIRT087533	hsa-miR-1250-3p	HITS-CLIP	19536157
MIRT087528	hsa-miR-153-5p	HITS-CLIP	19536157
MIRT713124	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT087540	hsa-miR-5696	HITS-CLIP	19536157
MIRT087531	hsa-miR-579-3p	HITS-CLIP	19536157
MIRT087539	hsa-miR-664b-3p	HITS-CLIP	19536157
MIRT713123	hsa-miR-30a-3p	HITS-CLIP	19536157
MIRT713122	hsa-miR-30d-3p	HITS-CLIP	19536157
MIRT713121	hsa-miR-30e-3p	HITS-CLIP	19536157
MIRT087548	hsa-miR-33b-5p	PAR-CLIP	20371350
MIRT028247	hsa-miR-33a-5p	PAR-CLIP	20371350
MIRT087551	hsa-miR-4464	PAR-CLIP	20371350
MIRT087552	hsa-miR-4748	PAR-CLIP	20371350
MIRT301127	hsa-miR-586	PAR-CLIP	20371350
MIRT087553	hsa-miR-5087	PAR-CLIP	20371350
MIRT087549	hsa-miR-2113	PAR-CLIP	20371350
MIRT087555	hsa-miR-107	PAR-CLIP	20371350
MIRT027235	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT087559	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT087554	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT087556	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT087557	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT087568	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT087560	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT032075	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT087561	hsa-miR-660-5p	PAR-CLIP	20371350
MIRT561357	hsa-miR-4699-3p	PAR-CLIP	20371350
MIRT087558	hsa-miR-330-3p	PAR-CLIP	20371350
MIRT087564	hsa-miR-4310	PAR-CLIP	20371350
MIRT087569	hsa-miR-7157-5p	PAR-CLIP	20371350
MIRT087566	hsa-miR-4729	PAR-CLIP	20371350
MIRT254727	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT561356	hsa-miR-6793-3p	PAR-CLIP	20371350
MIRT087567	hsa-miR-5591-3p	PAR-CLIP	20371350
MIRT520018	hsa-miR-648	PAR-CLIP	20371350
MIRT520017	hsa-miR-4267	PAR-CLIP	20371350
MIRT561358	hsa-miR-198	PAR-CLIP	20371350
MIRT520015	hsa-miR-3657	PAR-CLIP	20371350
MIRT520014	hsa-miR-4669	PAR-CLIP	20371350
MIRT520013	hsa-miR-142-3p	PAR-CLIP	20371350
MIRT087555	hsa-miR-107	PAR-CLIP	20371350
MIRT027235	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT087559	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT087554	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT087556	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT087557	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT087568	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT087560	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT032075	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT087561	hsa-miR-660-5p	PAR-CLIP	20371350
MIRT561357	hsa-miR-4699-3p	PAR-CLIP	20371350
MIRT087558	hsa-miR-330-3p	PAR-CLIP	20371350
MIRT087564	hsa-miR-4310	PAR-CLIP	20371350
MIRT087569	hsa-miR-7157-5p	PAR-CLIP	20371350
MIRT087566	hsa-miR-4729	PAR-CLIP	20371350
MIRT254727	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT561356	hsa-miR-6793-3p	PAR-CLIP	20371350
MIRT087567	hsa-miR-5591-3p	PAR-CLIP	20371350
MIRT520018	hsa-miR-648	PAR-CLIP	20371350
MIRT520017	hsa-miR-4267	PAR-CLIP	20371350
MIRT561358	hsa-miR-198	PAR-CLIP	20371350
MIRT520015	hsa-miR-3657	PAR-CLIP	20371350
MIRT520014	hsa-miR-4669	PAR-CLIP	20371350
MIRT520013	hsa-miR-142-3p	PAR-CLIP	20371350
MIRT087555	hsa-miR-107	PAR-CLIP	20371350
MIRT027235	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT087559	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT087554	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT087556	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT087557	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT087568	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT087560	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT032075	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT087561	hsa-miR-660-5p	PAR-CLIP	20371350
MIRT561357	hsa-miR-4699-3p	PAR-CLIP	20371350
MIRT087558	hsa-miR-330-3p	PAR-CLIP	20371350
MIRT087564	hsa-miR-4310	PAR-CLIP	20371350
MIRT087569	hsa-miR-7157-5p	PAR-CLIP	20371350
MIRT087566	hsa-miR-4729	PAR-CLIP	20371350
MIRT254727	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT561356	hsa-miR-6793-3p	PAR-CLIP	20371350
MIRT087567	hsa-miR-5591-3p	PAR-CLIP	20371350
MIRT087548	hsa-miR-33b-5p	PAR-CLIP	21572407
MIRT028247	hsa-miR-33a-5p	PAR-CLIP	21572407
MIRT552703	hsa-miR-4311	PAR-CLIP	21572407
MIRT552702	hsa-miR-1276	PAR-CLIP	21572407
MIRT301126	hsa-miR-583	PAR-CLIP	21572407
MIRT552701	hsa-miR-32-3p	PAR-CLIP	21572407
MIRT087547	hsa-miR-598-3p	PAR-CLIP	21572407
MIRT301127	hsa-miR-586	PAR-CLIP	21572407
MIRT552700	hsa-miR-1245b-3p	PAR-CLIP	21572407
MIRT087553	hsa-miR-5087	PAR-CLIP	21572407
MIRT552699	hsa-miR-5100	PAR-CLIP	21572407
MIRT552698	hsa-miR-3942-3p	PAR-CLIP	21572407
MIRT087549	hsa-miR-2113	PAR-CLIP	21572407
MIRT087548	hsa-miR-33b-5p	PAR-CLIP	21572407
MIRT028247	hsa-miR-33a-5p	PAR-CLIP	21572407
MIRT087551	hsa-miR-4464	PAR-CLIP	21572407
MIRT087552	hsa-miR-4748	PAR-CLIP	21572407
MIRT301127	hsa-miR-586	PAR-CLIP	21572407
MIRT087553	hsa-miR-5087	PAR-CLIP	21572407
MIRT087549	hsa-miR-2113	PAR-CLIP	21572407
MIRT520018	hsa-miR-648	PAR-CLIP	23446348
MIRT520017	hsa-miR-4267	PAR-CLIP	23446348
MIRT520016	hsa-miR-1289	PAR-CLIP	23446348
MIRT520015	hsa-miR-3657	PAR-CLIP	23446348
MIRT520014	hsa-miR-4669	PAR-CLIP	23446348
MIRT520013	hsa-miR-142-3p	PAR-CLIP	23446348
MIRT713127	hsa-miR-34b-3p	HITS-CLIP	19536157
MIRT713126	hsa-miR-6865-3p	HITS-CLIP	19536157
MIRT713125	hsa-miR-3620-3p	HITS-CLIP	19536157
MIRT087533	hsa-miR-1250-3p	HITS-CLIP	19536157
MIRT087528	hsa-miR-153-5p	HITS-CLIP	19536157
MIRT713124	hsa-miR-205-5p	HITS-CLIP	19536157
MIRT087540	hsa-miR-5696	HITS-CLIP	19536157
MIRT087531	hsa-miR-579-3p	HITS-CLIP	19536157
MIRT087539	hsa-miR-664b-3p	HITS-CLIP	19536157
MIRT713123	hsa-miR-30a-3p	HITS-CLIP	19536157
MIRT713122	hsa-miR-30d-3p	HITS-CLIP	19536157
MIRT713121	hsa-miR-30e-3p	HITS-CLIP	19536157
MIRT087548	hsa-miR-33b-5p	PAR-CLIP	20371350
MIRT028247	hsa-miR-33a-5p	PAR-CLIP	20371350
MIRT087551	hsa-miR-4464	PAR-CLIP	20371350
MIRT087552	hsa-miR-4748	PAR-CLIP	20371350
MIRT301127	hsa-miR-586	PAR-CLIP	20371350
MIRT087553	hsa-miR-5087	PAR-CLIP	20371350
MIRT087549	hsa-miR-2113	PAR-CLIP	20371350
MIRT087555	hsa-miR-107	PAR-CLIP	20371350
MIRT027235	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT087559	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT087554	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT087556	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT087557	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT087568	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT087560	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT032075	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT087561	hsa-miR-660-5p	PAR-CLIP	20371350
MIRT561357	hsa-miR-4699-3p	PAR-CLIP	20371350
MIRT087558	hsa-miR-330-3p	PAR-CLIP	20371350
MIRT087564	hsa-miR-4310	PAR-CLIP	20371350
MIRT087569	hsa-miR-7157-5p	PAR-CLIP	20371350
MIRT087566	hsa-miR-4729	PAR-CLIP	20371350
MIRT254727	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT561356	hsa-miR-6793-3p	PAR-CLIP	20371350
MIRT087567	hsa-miR-5591-3p	PAR-CLIP	20371350
MIRT520018	hsa-miR-648	PAR-CLIP	20371350
MIRT520017	hsa-miR-4267	PAR-CLIP	20371350
MIRT561358	hsa-miR-198	PAR-CLIP	20371350
MIRT520015	hsa-miR-3657	PAR-CLIP	20371350
MIRT520014	hsa-miR-4669	PAR-CLIP	20371350
MIRT520013	hsa-miR-142-3p	PAR-CLIP	20371350
MIRT087555	hsa-miR-107	PAR-CLIP	20371350
MIRT027235	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT087559	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT087554	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT087556	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT087557	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT087568	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT087560	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT032075	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT087561	hsa-miR-660-5p	PAR-CLIP	20371350
MIRT561357	hsa-miR-4699-3p	PAR-CLIP	20371350
MIRT087558	hsa-miR-330-3p	PAR-CLIP	20371350
MIRT087564	hsa-miR-4310	PAR-CLIP	20371350
MIRT087569	hsa-miR-7157-5p	PAR-CLIP	20371350
MIRT087566	hsa-miR-4729	PAR-CLIP	20371350
MIRT254727	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT561356	hsa-miR-6793-3p	PAR-CLIP	20371350
MIRT087567	hsa-miR-5591-3p	PAR-CLIP	20371350
MIRT520018	hsa-miR-648	PAR-CLIP	20371350
MIRT520017	hsa-miR-4267	PAR-CLIP	20371350
MIRT561358	hsa-miR-198	PAR-CLIP	20371350
MIRT520015	hsa-miR-3657	PAR-CLIP	20371350
MIRT520014	hsa-miR-4669	PAR-CLIP	20371350
MIRT520013	hsa-miR-142-3p	PAR-CLIP	20371350
MIRT087555	hsa-miR-107	PAR-CLIP	20371350
MIRT027235	hsa-miR-103a-3p	PAR-CLIP	20371350
MIRT087559	hsa-miR-424-5p	PAR-CLIP	20371350
MIRT087554	hsa-miR-15a-5p	PAR-CLIP	20371350
MIRT087556	hsa-miR-15b-5p	PAR-CLIP	20371350
MIRT087557	hsa-miR-195-5p	PAR-CLIP	20371350
MIRT087568	hsa-miR-6838-5p	PAR-CLIP	20371350
MIRT087560	hsa-miR-497-5p	PAR-CLIP	20371350
MIRT032075	hsa-miR-16-5p	PAR-CLIP	20371350
MIRT087561	hsa-miR-660-5p	PAR-CLIP	20371350
MIRT561357	hsa-miR-4699-3p	PAR-CLIP	20371350
MIRT087558	hsa-miR-330-3p	PAR-CLIP	20371350
MIRT087564	hsa-miR-4310	PAR-CLIP	20371350
MIRT087569	hsa-miR-7157-5p	PAR-CLIP	20371350
MIRT087566	hsa-miR-4729	PAR-CLIP	20371350
MIRT254727	hsa-miR-186-3p	PAR-CLIP	20371350
MIRT561356	hsa-miR-6793-3p	PAR-CLIP	20371350
MIRT087567	hsa-miR-5591-3p	PAR-CLIP	20371350
MIRT087548	hsa-miR-33b-5p	PAR-CLIP	21572407
MIRT028247	hsa-miR-33a-5p	PAR-CLIP	21572407
MIRT552703	hsa-miR-4311	PAR-CLIP	21572407
MIRT552702	hsa-miR-1276	PAR-CLIP	21572407
MIRT301126	hsa-miR-583	PAR-CLIP	21572407
MIRT552701	hsa-miR-32-3p	PAR-CLIP	21572407
MIRT087547	hsa-miR-598-3p	PAR-CLIP	21572407
MIRT301127	hsa-miR-586	PAR-CLIP	21572407
MIRT552700	hsa-miR-1245b-3p	PAR-CLIP	21572407
MIRT087553	hsa-miR-5087	PAR-CLIP	21572407
MIRT552699	hsa-miR-5100	PAR-CLIP	21572407
MIRT552698	hsa-miR-3942-3p	PAR-CLIP	21572407
MIRT087549	hsa-miR-2113	PAR-CLIP	21572407
MIRT087548	hsa-miR-33b-5p	PAR-CLIP	21572407
MIRT028247	hsa-miR-33a-5p	PAR-CLIP	21572407
MIRT087551	hsa-miR-4464	PAR-CLIP	21572407
MIRT087552	hsa-miR-4748	PAR-CLIP	21572407
MIRT301127	hsa-miR-586	PAR-CLIP	21572407
MIRT087553	hsa-miR-5087	PAR-CLIP	21572407
MIRT087549	hsa-miR-2113	PAR-CLIP	21572407
MIRT520018	hsa-miR-648	PAR-CLIP	23446348
MIRT520017	hsa-miR-4267	PAR-CLIP	23446348
MIRT520016	hsa-miR-1289	PAR-CLIP	23446348
MIRT520015	hsa-miR-3657	PAR-CLIP	23446348
MIRT520014	hsa-miR-4669	PAR-CLIP	23446348
MIRT520013	hsa-miR-142-3p	PAR-CLIP	23446348
MIRT1500782	hsa-miR-103a	CLIP-seq
MIRT1500783	hsa-miR-1245	CLIP-seq
MIRT1500784	hsa-miR-1252	CLIP-seq
MIRT1500785	hsa-miR-1262	CLIP-seq
MIRT1500786	hsa-miR-1293	CLIP-seq
MIRT1500787	hsa-miR-129-5p	CLIP-seq
MIRT1500788	hsa-miR-142-5p	CLIP-seq
MIRT1500789	hsa-miR-15a	CLIP-seq
MIRT1500790	hsa-miR-15b	CLIP-seq
MIRT1500791	hsa-miR-16	CLIP-seq
MIRT1500792	hsa-miR-1910	CLIP-seq
MIRT1500793	hsa-miR-1914	CLIP-seq
MIRT1500794	hsa-miR-195	CLIP-seq
MIRT1500795	hsa-miR-219-5p	CLIP-seq
MIRT1500796	hsa-miR-31	CLIP-seq
MIRT1500797	hsa-miR-3134	CLIP-seq
MIRT1500798	hsa-miR-3145-3p	CLIP-seq
MIRT1500799	hsa-miR-3200-5p	CLIP-seq
MIRT1500800	hsa-miR-3202	CLIP-seq
MIRT1500801	hsa-miR-320a	CLIP-seq
MIRT1500802	hsa-miR-320b	CLIP-seq
MIRT1500803	hsa-miR-320c	CLIP-seq
MIRT1500804	hsa-miR-320d	CLIP-seq
MIRT1500805	hsa-miR-338-3p	CLIP-seq
MIRT1500806	hsa-miR-33a	CLIP-seq
MIRT1500807	hsa-miR-33b	CLIP-seq
MIRT1500808	hsa-miR-340	CLIP-seq
MIRT1500809	hsa-miR-3591-5p	CLIP-seq
MIRT1500810	hsa-miR-3606	CLIP-seq
MIRT1500811	hsa-miR-3613-3p	CLIP-seq
MIRT1500812	hsa-miR-365	CLIP-seq
MIRT1500813	hsa-miR-3682-3p	CLIP-seq
MIRT1500814	hsa-miR-3688-3p	CLIP-seq
MIRT1500815	hsa-miR-3688-5p	CLIP-seq
MIRT1500816	hsa-miR-382	CLIP-seq
MIRT1500817	hsa-miR-3908	CLIP-seq
MIRT1500818	hsa-miR-3978	CLIP-seq
MIRT1500819	hsa-miR-424	CLIP-seq
MIRT1500820	hsa-miR-4265	CLIP-seq
MIRT1500821	hsa-miR-4296	CLIP-seq
MIRT1500822	hsa-miR-4300	CLIP-seq
MIRT1500823	hsa-miR-4322	CLIP-seq
MIRT1500824	hsa-miR-4417	CLIP-seq
MIRT1500825	hsa-miR-4429	CLIP-seq
MIRT1500826	hsa-miR-4437	CLIP-seq
MIRT1500827	hsa-miR-4445	CLIP-seq
MIRT1500828	hsa-miR-4452	CLIP-seq
MIRT1500829	hsa-miR-4457	CLIP-seq
MIRT1500830	hsa-miR-4474-3p	CLIP-seq
MIRT1500831	hsa-miR-4476	CLIP-seq
MIRT1500832	hsa-miR-4483	CLIP-seq
MIRT1500833	hsa-miR-450b-5p	CLIP-seq
MIRT1500834	hsa-miR-4530	CLIP-seq
MIRT1500835	hsa-miR-4534	CLIP-seq
MIRT1500836	hsa-miR-455-3p	CLIP-seq
MIRT1500837	hsa-miR-4641	CLIP-seq
MIRT1500838	hsa-miR-4643	CLIP-seq
MIRT1500839	hsa-miR-4651	CLIP-seq
MIRT1500840	hsa-miR-4662a-5p	CLIP-seq
MIRT1500841	hsa-miR-4674	CLIP-seq
MIRT1500842	hsa-miR-4701-3p	CLIP-seq
MIRT1500843	hsa-miR-4717-3p	CLIP-seq
MIRT1500844	hsa-miR-4720-3p	CLIP-seq
MIRT1500845	hsa-miR-4724-5p	CLIP-seq
MIRT1500846	hsa-miR-4731-3p	CLIP-seq
MIRT1500847	hsa-miR-4738-3p	CLIP-seq
MIRT1500848	hsa-miR-4760-3p	CLIP-seq
MIRT1500849	hsa-miR-4766-5p	CLIP-seq
MIRT1500850	hsa-miR-4782-3p	CLIP-seq
MIRT1500851	hsa-miR-4795-3p	CLIP-seq
MIRT1500852	hsa-miR-4801	CLIP-seq
MIRT1500853	hsa-miR-4804-3p	CLIP-seq
MIRT1500854	hsa-miR-497	CLIP-seq
MIRT1500855	hsa-miR-507	CLIP-seq
MIRT1500856	hsa-miR-508-3p	CLIP-seq
MIRT1500857	hsa-miR-541	CLIP-seq
MIRT1500858	hsa-miR-557	CLIP-seq
MIRT1500859	hsa-miR-579	CLIP-seq
MIRT1500860	hsa-miR-593	CLIP-seq
MIRT1500861	hsa-miR-605	CLIP-seq
MIRT1500862	hsa-miR-608	CLIP-seq
MIRT1500863	hsa-miR-642b	CLIP-seq
MIRT1500864	hsa-miR-652	CLIP-seq
MIRT1500865	hsa-miR-654-5p	CLIP-seq
MIRT1500866	hsa-miR-664	CLIP-seq
MIRT1500867	hsa-miR-889	CLIP-seq
MIRT1500868	hsa-miR-920	CLIP-seq
MIRT1500869	hsa-miR-921	CLIP-seq
MIRT1500806	hsa-miR-33a	CLIP-seq
MIRT1500807	hsa-miR-33b	CLIP-seq
MIRT1555677	hsa-miR-548aa	CLIP-seq
MIRT1557323	hsa-miR-28-3p	CLIP-seq
MIRT1500798	hsa-miR-3145-3p	CLIP-seq
MIRT1500783	hsa-miR-1245	CLIP-seq
MIRT1500784	hsa-miR-1252	CLIP-seq
MIRT2150658	hsa-miR-1256	CLIP-seq
MIRT1500787	hsa-miR-129-5p	CLIP-seq
MIRT1500788	hsa-miR-142-5p	CLIP-seq
MIRT1500793	hsa-miR-1914	CLIP-seq
MIRT2150659	hsa-miR-2115	CLIP-seq
MIRT1500795	hsa-miR-219-5p	CLIP-seq
MIRT1557323	hsa-miR-28-3p	CLIP-seq
MIRT1500796	hsa-miR-31	CLIP-seq
MIRT2150660	hsa-miR-3128	CLIP-seq
MIRT1500797	hsa-miR-3134	CLIP-seq
MIRT1500798	hsa-miR-3145-3p	CLIP-seq
MIRT1500799	hsa-miR-3200-5p	CLIP-seq
MIRT1500801	hsa-miR-320a	CLIP-seq
MIRT1500802	hsa-miR-320b	CLIP-seq
MIRT1500803	hsa-miR-320c	CLIP-seq
MIRT1500804	hsa-miR-320d	CLIP-seq
MIRT2150661	hsa-miR-323b-3p	CLIP-seq
MIRT1500806	hsa-miR-33a	CLIP-seq
MIRT1500807	hsa-miR-33b	CLIP-seq
MIRT1500808	hsa-miR-340	CLIP-seq
MIRT2150662	hsa-miR-34b	CLIP-seq
MIRT1500809	hsa-miR-3591-5p	CLIP-seq
MIRT1500810	hsa-miR-3606	CLIP-seq
MIRT1500811	hsa-miR-3613-3p	CLIP-seq
MIRT1500813	hsa-miR-3682-3p	CLIP-seq
MIRT1500814	hsa-miR-3688-3p	CLIP-seq
MIRT1500815	hsa-miR-3688-5p	CLIP-seq
MIRT1500816	hsa-miR-382	CLIP-seq
MIRT1500818	hsa-miR-3978	CLIP-seq
MIRT1500820	hsa-miR-4265	CLIP-seq
MIRT1500821	hsa-miR-4296	CLIP-seq
MIRT1500822	hsa-miR-4300	CLIP-seq
MIRT1500823	hsa-miR-4322	CLIP-seq
MIRT1500824	hsa-miR-4417	CLIP-seq
MIRT1500825	hsa-miR-4429	CLIP-seq
MIRT2150663	hsa-miR-4433	CLIP-seq
MIRT1500826	hsa-miR-4437	CLIP-seq
MIRT1500827	hsa-miR-4445	CLIP-seq
MIRT1500828	hsa-miR-4452	CLIP-seq
MIRT1500829	hsa-miR-4457	CLIP-seq
MIRT1500830	hsa-miR-4474-3p	CLIP-seq
MIRT1500833	hsa-miR-450b-5p	CLIP-seq
MIRT1500835	hsa-miR-4534	CLIP-seq
MIRT1500838	hsa-miR-4643	CLIP-seq
MIRT1500839	hsa-miR-4651	CLIP-seq
MIRT1500840	hsa-miR-4662a-5p	CLIP-seq
MIRT1500841	hsa-miR-4674	CLIP-seq
MIRT2150664	hsa-miR-4682	CLIP-seq
MIRT1500843	hsa-miR-4717-3p	CLIP-seq
MIRT2150665	hsa-miR-4720-5p	CLIP-seq
MIRT1500846	hsa-miR-4731-3p	CLIP-seq
MIRT1500848	hsa-miR-4760-3p	CLIP-seq
MIRT1500850	hsa-miR-4782-3p	CLIP-seq
MIRT1500851	hsa-miR-4795-3p	CLIP-seq
MIRT2150666	hsa-miR-4799-3p	CLIP-seq
MIRT1500852	hsa-miR-4801	CLIP-seq
MIRT1500855	hsa-miR-507	CLIP-seq
MIRT1500856	hsa-miR-508-3p	CLIP-seq
MIRT2150667	hsa-miR-516a-3p	CLIP-seq
MIRT1555677	hsa-miR-548aa	CLIP-seq
MIRT1500858	hsa-miR-557	CLIP-seq
MIRT1500859	hsa-miR-579	CLIP-seq
MIRT1500862	hsa-miR-608	CLIP-seq
MIRT1500863	hsa-miR-642b	CLIP-seq
MIRT1500864	hsa-miR-652	CLIP-seq
MIRT1500866	hsa-miR-664	CLIP-seq
MIRT1500868	hsa-miR-920	CLIP-seq
MIRT1500869	hsa-miR-921	CLIP-seq
MIRT2150658	hsa-miR-1256	CLIP-seq
MIRT1500787	hsa-miR-129-5p	CLIP-seq
MIRT2371137	hsa-miR-132	CLIP-seq
MIRT1500788	hsa-miR-142-5p	CLIP-seq
MIRT1500792	hsa-miR-1910	CLIP-seq
MIRT1500793	hsa-miR-1914	CLIP-seq
MIRT2371138	hsa-miR-204	CLIP-seq
MIRT2371139	hsa-miR-211	CLIP-seq
MIRT2150659	hsa-miR-2115	CLIP-seq
MIRT2371140	hsa-miR-212	CLIP-seq
MIRT2150660	hsa-miR-3128	CLIP-seq
MIRT1500797	hsa-miR-3134	CLIP-seq
MIRT1500799	hsa-miR-3200-5p	CLIP-seq
MIRT1500801	hsa-miR-320a	CLIP-seq
MIRT1500802	hsa-miR-320b	CLIP-seq
MIRT1500803	hsa-miR-320c	CLIP-seq
MIRT1500804	hsa-miR-320d	CLIP-seq
MIRT2150661	hsa-miR-323b-3p	CLIP-seq
MIRT1500805	hsa-miR-338-3p	CLIP-seq
MIRT1500806	hsa-miR-33a	CLIP-seq
MIRT1500807	hsa-miR-33b	CLIP-seq
MIRT1500808	hsa-miR-340	CLIP-seq
MIRT2150662	hsa-miR-34b	CLIP-seq
MIRT1500811	hsa-miR-3613-3p	CLIP-seq
MIRT1500812	hsa-miR-365	CLIP-seq
MIRT2371141	hsa-miR-3662	CLIP-seq
MIRT1500814	hsa-miR-3688-3p	CLIP-seq
MIRT1500816	hsa-miR-382	CLIP-seq
MIRT1500817	hsa-miR-3908	CLIP-seq
MIRT1500818	hsa-miR-3978	CLIP-seq
MIRT1500820	hsa-miR-4265	CLIP-seq
MIRT1500821	hsa-miR-4296	CLIP-seq
MIRT1500822	hsa-miR-4300	CLIP-seq
MIRT1500823	hsa-miR-4322	CLIP-seq
MIRT2371142	hsa-miR-4328	CLIP-seq
MIRT1500824	hsa-miR-4417	CLIP-seq
MIRT1500825	hsa-miR-4429	CLIP-seq
MIRT2150663	hsa-miR-4433	CLIP-seq
MIRT1500826	hsa-miR-4437	CLIP-seq
MIRT1500828	hsa-miR-4452	CLIP-seq
MIRT1500829	hsa-miR-4457	CLIP-seq
MIRT1500833	hsa-miR-450b-5p	CLIP-seq
MIRT1500834	hsa-miR-4530	CLIP-seq
MIRT1500835	hsa-miR-4534	CLIP-seq
MIRT1500836	hsa-miR-455-3p	CLIP-seq
MIRT1500837	hsa-miR-4641	CLIP-seq
MIRT1500838	hsa-miR-4643	CLIP-seq
MIRT1500840	hsa-miR-4662a-5p	CLIP-seq
MIRT1500841	hsa-miR-4674	CLIP-seq
MIRT2150664	hsa-miR-4682	CLIP-seq
MIRT1500843	hsa-miR-4717-3p	CLIP-seq
MIRT2150665	hsa-miR-4720-5p	CLIP-seq
MIRT1500846	hsa-miR-4731-3p	CLIP-seq
MIRT1500847	hsa-miR-4738-3p	CLIP-seq
MIRT2371143	hsa-miR-4742-3p	CLIP-seq
MIRT2371144	hsa-miR-4755-5p	CLIP-seq
MIRT1500848	hsa-miR-4760-3p	CLIP-seq
MIRT1500849	hsa-miR-4766-5p	CLIP-seq
MIRT1500851	hsa-miR-4795-3p	CLIP-seq
MIRT2150666	hsa-miR-4799-3p	CLIP-seq
MIRT1500852	hsa-miR-4801	CLIP-seq
MIRT1500855	hsa-miR-507	CLIP-seq
MIRT2371145	hsa-miR-515-5p	CLIP-seq
MIRT2150667	hsa-miR-516a-3p	CLIP-seq
MIRT2371146	hsa-miR-520d-5p	CLIP-seq
MIRT2371147	hsa-miR-524-5p	CLIP-seq
MIRT1500858	hsa-miR-557	CLIP-seq
MIRT1500859	hsa-miR-579	CLIP-seq
MIRT2371148	hsa-miR-587	CLIP-seq
MIRT1500860	hsa-miR-593	CLIP-seq
MIRT2371149	hsa-miR-603	CLIP-seq
MIRT2371150	hsa-miR-623	CLIP-seq
MIRT1500863	hsa-miR-642b	CLIP-seq
MIRT1500864	hsa-miR-652	CLIP-seq
MIRT1500866	hsa-miR-664	CLIP-seq
MIRT2371151	hsa-miR-885-5p	CLIP-seq
MIRT1500868	hsa-miR-920	CLIP-seq
MIRT2150661	hsa-miR-323b-3p	CLIP-seq
MIRT2150662	hsa-miR-34b	CLIP-seq
MIRT1500829	hsa-miR-4457	CLIP-seq
MIRT1500838	hsa-miR-4643	CLIP-seq
MIRT1500843	hsa-miR-4717-3p	CLIP-seq
MIRT1500846	hsa-miR-4731-3p	CLIP-seq
MIRT1500852	hsa-miR-4801	CLIP-seq
MIRT1500863	hsa-miR-642b	CLIP-seq
MIRT1500864	hsa-miR-652	CLIP-seq
MIRT1500811	hsa-miR-3613-3p	CLIP-seq
MIRT1500829	hsa-miR-4457	CLIP-seq
MIRT1500840	hsa-miR-4662a-5p	CLIP-seq
MIRT1500846	hsa-miR-4731-3p	CLIP-seq
MIRT1500852	hsa-miR-4801	CLIP-seq
MIRT2371146	hsa-miR-520d-5p	CLIP-seq
MIRT2371147	hsa-miR-524-5p	CLIP-seq
MIRT1500861	hsa-miR-605	CLIP-seq
MIRT1500783	hsa-miR-1245	CLIP-seq
MIRT2371137	hsa-miR-132	CLIP-seq
MIRT1500788	hsa-miR-142-5p	CLIP-seq
MIRT2371138	hsa-miR-204	CLIP-seq
MIRT2371139	hsa-miR-211	CLIP-seq
MIRT2150659	hsa-miR-2115	CLIP-seq
MIRT2371140	hsa-miR-212	CLIP-seq
MIRT1500795	hsa-miR-219-5p	CLIP-seq
MIRT1557323	hsa-miR-28-3p	CLIP-seq
MIRT1500796	hsa-miR-31	CLIP-seq
MIRT1500797	hsa-miR-3134	CLIP-seq
MIRT1500798	hsa-miR-3145-3p	CLIP-seq
MIRT2664591	hsa-miR-3185	CLIP-seq
MIRT1500799	hsa-miR-3200-5p	CLIP-seq
MIRT1500801	hsa-miR-320a	CLIP-seq
MIRT1500802	hsa-miR-320b	CLIP-seq
MIRT1500803	hsa-miR-320c	CLIP-seq
MIRT1500804	hsa-miR-320d	CLIP-seq
MIRT2150661	hsa-miR-323b-3p	CLIP-seq
MIRT1500808	hsa-miR-340	CLIP-seq
MIRT1500809	hsa-miR-3591-5p	CLIP-seq
MIRT1500810	hsa-miR-3606	CLIP-seq
MIRT1500811	hsa-miR-3613-3p	CLIP-seq
MIRT1500813	hsa-miR-3682-3p	CLIP-seq
MIRT1500814	hsa-miR-3688-3p	CLIP-seq
MIRT1500815	hsa-miR-3688-5p	CLIP-seq
MIRT1500816	hsa-miR-382	CLIP-seq
MIRT1500818	hsa-miR-3978	CLIP-seq
MIRT2371142	hsa-miR-4328	CLIP-seq
MIRT1500825	hsa-miR-4429	CLIP-seq
MIRT2150663	hsa-miR-4433	CLIP-seq
MIRT1500827	hsa-miR-4445	CLIP-seq
MIRT1500829	hsa-miR-4457	CLIP-seq
MIRT1500830	hsa-miR-4474-3p	CLIP-seq
MIRT1500835	hsa-miR-4534	CLIP-seq
MIRT1500838	hsa-miR-4643	CLIP-seq
MIRT1500840	hsa-miR-4662a-5p	CLIP-seq
MIRT2150664	hsa-miR-4682	CLIP-seq
MIRT2664592	hsa-miR-4709-3p	CLIP-seq
MIRT1500843	hsa-miR-4717-3p	CLIP-seq
MIRT1500846	hsa-miR-4731-3p	CLIP-seq
MIRT1500847	hsa-miR-4738-3p	CLIP-seq
MIRT2371143	hsa-miR-4742-3p	CLIP-seq
MIRT2371144	hsa-miR-4755-5p	CLIP-seq
MIRT1500850	hsa-miR-4782-3p	CLIP-seq
MIRT1500851	hsa-miR-4795-3p	CLIP-seq
MIRT1500852	hsa-miR-4801	CLIP-seq
MIRT1500856	hsa-miR-508-3p	CLIP-seq
MIRT2150667	hsa-miR-516a-3p	CLIP-seq
MIRT2371146	hsa-miR-520d-5p	CLIP-seq
MIRT2371147	hsa-miR-524-5p	CLIP-seq
MIRT2371148	hsa-miR-587	CLIP-seq
MIRT1500860	hsa-miR-593	CLIP-seq
MIRT1500861	hsa-miR-605	CLIP-seq
MIRT2371150	hsa-miR-623	CLIP-seq
MIRT1500863	hsa-miR-642b	CLIP-seq
MIRT1500864	hsa-miR-652	CLIP-seq
MIRT2371151	hsa-miR-885-5p	CLIP-seq
MIRT1500869	hsa-miR-921	CLIP-seq
MIRT1500783	hsa-miR-1245	CLIP-seq
MIRT2371137	hsa-miR-132	CLIP-seq
MIRT1500788	hsa-miR-142-5p	CLIP-seq
MIRT2371138	hsa-miR-204	CLIP-seq
MIRT2371139	hsa-miR-211	CLIP-seq
MIRT2150659	hsa-miR-2115	CLIP-seq
MIRT2371140	hsa-miR-212	CLIP-seq
MIRT1500795	hsa-miR-219-5p	CLIP-seq
MIRT1557323	hsa-miR-28-3p	CLIP-seq
MIRT1500796	hsa-miR-31	CLIP-seq
MIRT1500797	hsa-miR-3134	CLIP-seq
MIRT1500798	hsa-miR-3145-3p	CLIP-seq
MIRT2664591	hsa-miR-3185	CLIP-seq
MIRT1500799	hsa-miR-3200-5p	CLIP-seq
MIRT1500801	hsa-miR-320a	CLIP-seq
MIRT1500802	hsa-miR-320b	CLIP-seq
MIRT1500803	hsa-miR-320c	CLIP-seq
MIRT1500804	hsa-miR-320d	CLIP-seq
MIRT2150661	hsa-miR-323b-3p	CLIP-seq
MIRT1500808	hsa-miR-340	CLIP-seq
MIRT1500809	hsa-miR-3591-5p	CLIP-seq
MIRT1500810	hsa-miR-3606	CLIP-seq
MIRT1500811	hsa-miR-3613-3p	CLIP-seq
MIRT1500813	hsa-miR-3682-3p	CLIP-seq
MIRT1500814	hsa-miR-3688-3p	CLIP-seq
MIRT1500815	hsa-miR-3688-5p	CLIP-seq
MIRT1500816	hsa-miR-382	CLIP-seq
MIRT1500818	hsa-miR-3978	CLIP-seq
MIRT2371142	hsa-miR-4328	CLIP-seq
MIRT1500825	hsa-miR-4429	CLIP-seq
MIRT2150663	hsa-miR-4433	CLIP-seq
MIRT1500827	hsa-miR-4445	CLIP-seq
MIRT1500829	hsa-miR-4457	CLIP-seq
MIRT1500830	hsa-miR-4474-3p	CLIP-seq
MIRT1500835	hsa-miR-4534	CLIP-seq
MIRT1500838	hsa-miR-4643	CLIP-seq
MIRT1500840	hsa-miR-4662a-5p	CLIP-seq
MIRT2150664	hsa-miR-4682	CLIP-seq
MIRT2664592	hsa-miR-4709-3p	CLIP-seq
MIRT1500843	hsa-miR-4717-3p	CLIP-seq
MIRT1500846	hsa-miR-4731-3p	CLIP-seq
MIRT1500847	hsa-miR-4738-3p	CLIP-seq
MIRT2371143	hsa-miR-4742-3p	CLIP-seq
MIRT2371144	hsa-miR-4755-5p	CLIP-seq
MIRT1500850	hsa-miR-4782-3p	CLIP-seq
MIRT1500851	hsa-miR-4795-3p	CLIP-seq
MIRT1500852	hsa-miR-4801	CLIP-seq
MIRT1500856	hsa-miR-508-3p	CLIP-seq
MIRT2150667	hsa-miR-516a-3p	CLIP-seq
MIRT2371146	hsa-miR-520d-5p	CLIP-seq
MIRT2371147	hsa-miR-524-5p	CLIP-seq
MIRT2371148	hsa-miR-587	CLIP-seq
MIRT1500860	hsa-miR-593	CLIP-seq
MIRT1500861	hsa-miR-605	CLIP-seq
MIRT2371150	hsa-miR-623	CLIP-seq
MIRT1500863	hsa-miR-642b	CLIP-seq
MIRT1500864	hsa-miR-652	CLIP-seq
MIRT2371151	hsa-miR-885-5p	CLIP-seq
MIRT1500869	hsa-miR-921	CLIP-seq

Show/Hide all(40)

GO ID	Ontology	Definition	Evidence	Reference
GO:0002028	Process	Regulation of sodium ion transport	IDA	16728661
GO:0003779	Function	Actin binding	IEA
GO:0005159	Function	Insulin-like growth factor receptor binding	ISS
GO:0005515	Function	Protein binding	IPI	10713667, 11697890, 12524439, 14676191, 14690447, 14743216, 15023544, 15677482, 16545136, 16672277, 16775625, 16959763, 17700517, 17962809, 17979178, 18045992, 18242179, 18397886, 18458160, 19172738, 19553522, 19615732, 19640509, 19860830, 20642453, 20936779, 21988832, 23075850, 235
GO:0005737	Component	Cytoplasm	IBA
GO:0005737	Component	Cytoplasm	IEA
GO:0005737	Component	Cytoplasm	ISS
GO:0005739	Component	Mitochondrion	IDA	31906564
GO:0005829	Component	Cytosol	TAS
GO:0005886	Component	Plasma membrane	IDA	16728661
GO:0006713	Process	Glucocorticoid catabolic process	IDA	15790729
GO:0006886	Process	Intracellular protein transport	IEA
GO:0006886	Process	Intracellular protein transport	ISS
GO:0007165	Process	Signal transduction	IBA
GO:0008104	Process	Intracellular protein localization	IBA
GO:0014704	Component	Intercalated disc	IC	16728661
GO:0017080	Function	Sodium channel regulator activity	IDA	16728661
GO:0019899	Function	Enzyme binding	IPI	17255105
GO:0019904	Function	Protein domain specific binding	IEA
GO:0019904	Function	Protein domain specific binding	ISS
GO:0021762	Process	Substantia nigra development	HEP	22926577
GO:0035259	Function	Nuclear glucocorticoid receptor binding	IPI	9079630
GO:0042802	Function	Identical protein binding	IEA
GO:0042802	Function	Identical protein binding	IPI	17085597, 17979178
GO:0042921	Process	Nuclear receptor-mediated glucocorticoid signaling pathway	IDA	15790729
GO:0044325	Function	Transmembrane transporter binding	IEA
GO:0044325	Function	Transmembrane transporter binding	IPI	11953308, 16728661
GO:0045202	Component	Synapse	IEA
GO:0045664	Process	Regulation of neuron differentiation	ISS
GO:0045893	Process	Positive regulation of DNA-templated transcription	IDA	15790729
GO:0046982	Function	Protein heterodimerization activity	IPI	11953308
GO:0048167	Process	Regulation of synaptic plasticity	ISS
GO:0050774	Process	Negative regulation of dendrite morphogenesis	IEA
GO:0050774	Process	Negative regulation of dendrite morphogenesis	ISS
GO:0070062	Component	Extracellular exosome	HDA	19056867, 19199708, 20458337
GO:0086010	Process	Membrane depolarization during action potential	IDA	16728661
GO:0098793	Component	Presynapse	IEA
GO:0098978	Component	Glutamatergic synapse	IEA
GO:0099171	Process	Presynaptic modulation of chemical synaptic transmission	IEA
GO:0150048	Component	Cerebellar granule cell to Purkinje cell synapse	IEA

MIM	HGNC	e!Ensembl
113508	12853	ENSG00000128245

Protein

UniProt ID

Q04917

Protein name

14-3-3 protein eta (Protein AS1)

Protein function

Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways. Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif. Binding generally resu

PDB

2C63 , 2C74 , 7NMZ

Family and domains

Pfam

Accession	ID	Position in sequence	Description	Type
PF00244	14-03-2003	10 → 234	14-3-3 protein	Domain

Tissue specificity

TISSUE SPECIFICITY: Expressed mainly in the brain and present in other tissues albeit at lower levels.

Sequence

MGDREQLLQRARLAEQAERYDDMASAMKAVTELNEPLSNEDRNLLSVAYKNVVGARRSSW
RVISSIEQKTMADGNEKKLEKVKAYREKIEKELETVCNDVLSLLDKFLIKNCNDFQYESK
VFYLKMKGDYYRYLAEVASGEKKNSVVEASEAAYKEAFEISKEQMQPTHPIRLGLALNFS
VFYYEIQNAPEQACLLAKQAFDDAIAELDTLNEDSYKDSTLIMQLLRDNLTLWTSDQQDE
EAGEGN

Sequence length

246

Interactions

View interactions

	KEGG		Reactome
	Cell cycle Oocyte meiosis PI3K-Akt signaling pathway Hippo signaling pathway Hepatitis C Viral carcinogenesis		Activation of BAD and translocation to mitochondria RHO GTPases activate PKNs TP53 Regulates Metabolic Genes Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex

Show/Hide Unknown Diseases (2)

Disease merge term	Disease name	Evidence	References	Source
Unknown Includes: (1) ClinVar NON-pathogenic variants (Uncertain, Benign, Conflicting, VUS), (2) GenCC associations, (3) GWAS associations, (4) CBGDA evidence-based associations. NOTE: Diseases with pathogenic evidence are excluded to avoid conflicts.
Breast Cancer	Breast cancer	N/A	N/A	GWAS
Diabetes	Type 2 diabetes	N/A	N/A	GWAS

Show/Hide Text Mining Associations (25)

Disease Name	Relationship Type	References
Associations from Text Mining Disease associations identified through Pubtator
Adenoma Oxyphilic	Associate	29704241
Arthritis Rheumatoid	Associate	24751211, 26449724, 35008549
Arthritis Rheumatoid	Stimulate	30915732
Bipolar Disorder	Associate	19160447
Breast Neoplasms	Associate	20534901
Carcinoma Ductal	Associate	20534901, 21197096
Carcinoma Hepatocellular	Associate	30572915
Cartilage Diseases	Inhibit	35008549
Cognitive Dysfunction	Associate	19160447
Glioma	Associate	26370624
HIV Infections	Associate	33373444
Hypoxia Brain	Associate	38129425
Inflammation	Stimulate	24751211
Joint Diseases	Associate	24751211, 35008549
Mental Disorders	Associate	19160447
Neoplasms	Associate	35902926
Neurocognitive Disorders	Associate	33373444
Osteoporosis	Associate	38129425
Parkinson Disease	Associate	37947401
Psychotic Disorders	Associate	19160447
Schizophrenia	Associate	19160447
Stomach Neoplasms	Associate	37415737
Thyroid Cancer Papillary	Associate	35902926
Thyroid Neoplasms	Associate	33272009
Tuberculosis Multidrug Resistant	Associate	30572915

YWHAH (tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta)