VDAC2 (voltage dependent anion channel 2)
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Gene
Gene information from NCBI Gene database.
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| Entrez ID | 7417 |
| Gene name | Voltage dependent anion channel 2 |
| Gene symbol | VDAC2 |
| Synonyms (NCBI Gene) |
POR
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| Chromosome | 10 |
| Chromosome location | 10q22.2 |
| Summary | This gene encodes a member of the voltage-dependent anion channel pore-forming family of proteins that are considered the main pathway for metabolite diffusion across the mitochondrial outer membrane. The encoded protein is also thought to be involved in |
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miRNA
miRNA information provided by mirtarbase database.
250
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Gene ontology (GO)
Gene Ontology (GO) annotations describing the biological processes, molecular functions, and cellular components associated with a gene.
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Other IDs
Other IDs provides unique identifiers for this gene in OMIM, HGNC, and Ensembl databases.
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Protein
Protein information from UniProt database.
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UniProt ID
Unique identifier for the protein in the UniProt database. Click to view detailed protein information.
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P45880 | ||||||||||
| Protein name | Non-selective voltage-gated ion channel VDAC2 (VDAC-2) (hVDAC2) (Outer mitochondrial membrane protein porin 2) | ||||||||||
| Protein function | Non-selective voltage-gated ion channel that mediates the transport of anions and cations through the mitochondrion outer membrane and plasma membrane (PubMed:8420959). The channel adopts an open conformation at zero mV and a closed conformation | ||||||||||
| PDB | 9EIH , 9EII , 9EIJ | ||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: Expressed in erythrocytes (at protein level) (PubMed:27641616). Expressed in all tissues examined (PubMed:8420959). {ECO:0000269|PubMed:27641616, ECO:0000269|PubMed:8420959}. | ||||||||||
| Sequence |
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| Sequence length | 294 | ||||||||||
| Interactions | View interactions | ||||||||||
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Associated diseases
Disease associations from ClinVar categorized as Causal (Pathogenic/Likely Pathogenic) or Unknown.
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