UCK2 (uridine-cytidine kinase 2)
Gene | |
Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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7371 |
Gene name
Gene Name - the full gene name approved by the HGNC.
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Uridine-cytidine kinase 2 |
Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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UCK2 |
Synonyms (NCBI Gene)
Gene synonyms aliases
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TSA903, UK, UMPK |
Chromosome
Chromosome number
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1 |
Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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1q24.1 |
Summary
Summary of gene provided in NCBI Entrez Gene.
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This gene encodes a pyrimidine ribonucleoside kinase. The encoded protein (EC 2.7.1.48) catalyzes phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP), respectively.[provided by RefSeq, Oct 2010] |
miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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Protein | |||||||||||
UniProt ID | Q9BZX2 | ||||||||||
Protein name | Uridine-cytidine kinase 2 (UCK 2) (EC 2.7.1.48) (Cytidine monophosphokinase 2) (Testis-specific protein TSA903) (Uridine monophosphokinase 2) | ||||||||||
Protein function | Phosphorylates uridine and cytidine to uridine monophosphate and cytidine monophosphate (PubMed:11306702, PubMed:11494055). Does not phosphorylate deoxyribonucleosides or purine ribonucleosides (PubMed:11306702). Can use ATP or GTP as a phosphat | ||||||||||
PDB | 1UDW , 1UEI , 1UEJ , 1UFQ , 1UJ2 , 1XRJ , 6N53 , 6N54 , 6N55 , 6PWZ , 7SQL | ||||||||||
Family and domains |
Pfam
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Tissue specificity | TISSUE SPECIFICITY: According to PubMed:8812458; testis-specific. According to PubMed:11306702, placenta-specific. {ECO:0000269|PubMed:8812458}. | ||||||||||
Sequence |
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Sequence length | 261 | ||||||||||
Interactions | View interactions |
Pathways
Pathway information has different metabolic/signaling pathways associated with genes.
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Associated diseases
Disease information provided by ClinVar, GenCC, and GWAS databases.
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