TUBB2A (tubulin beta 2A class IIa)
| Gene | |
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Entrez ID
Entrez Gene ID - the GENE ID in NCBI Gene database.
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7280 |
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Gene name
Gene Name - the full gene name approved by the HGNC.
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Tubulin beta 2A class IIa |
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Gene symbol
Gene Symbol - the official gene symbol approved by the HGNC.
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TUBB2A |
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Synonyms (NCBI Gene)
Gene synonyms aliases
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CDCBM5, TUBB, TUBB2 |
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Chromosome
Chromosome number
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6 |
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Chromosome location
Chromosomal Location - indicates the cytogenetic location of the gene or region on the chromosome.
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6p25.2 |
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Summary
Summary of gene provided in NCBI Entrez Gene.
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Microtubules, key participants in processes such as mitosis and intracellular transport, are composed of heterodimers of alpha- and beta-tubulins. The protein encoded by this gene is a beta-tubulin. Defects in this gene are associated with complex cortica |
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SNPs
SNP information provided by dbSNP.
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miRNA
miRNA information provided by mirtarbase database.
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Gene ontology (GO)
Gene ontology information of associated ontologies with gene provided by GO database.
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Other IDs
Other ids provides unique ids of gene in databases such as OMIM, HGNC, ENSEMBLE.
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| Protein | ||||||||||||||||
| UniProt ID | Q13885 | |||||||||||||||
| Protein name | Tubulin beta-2A chain (Tubulin beta class IIa) | |||||||||||||||
| Protein function | Tubulin is the major constituent of microtubules, a cylinder consisting of laterally associated linear protofilaments composed of alpha- and beta-tubulin heterodimers. Microtubules grow by the addition of GTP-tubulin dimers to the microtubule en | |||||||||||||||
| PDB | 7NVN , 8V3O , 8V3P | |||||||||||||||
| Family and domains |
Pfam
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| Tissue specificity | TISSUE SPECIFICITY: High expression in brain, where it represents 30% of all beta-tubulins. {ECO:0000269|PubMed:20191564}. | |||||||||||||||
| Sequence |
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| Sequence length | 445 | |||||||||||||||
| Interactions | View interactions | |||||||||||||||
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Associated diseases
Disease associations categorized as Causal (pathogenic variants), Unknown (uncertain genetic evidence), or Text Mining (literature-based associations)
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